Cell: is the smallest structural and functional unit of an organism, typically microscopic and consisting of cytoplasm and a nucleus enclosed in a membrane. Microscopic organisms typically consist of a single cell, which is either eukaryotic or prokaryotic.
Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
One of the most common pathologically relevant mutated variants of ALK-2 (activin receptor-like kinase-2) has a point mutation (R206H) in its Ser/Thr kinase domain that promotes uncontrolled...
Natural light-harvesting systems, such as photosynthetic pigment-protein complexes, efficiently transfer energy through space with high efficiency. Ultimately, we would like to understand th...
DATE: August 6th, 2020 TIME: 10:00am PT In recent years Lilly has implemented a Next Generation Research (NGR) initiative to improve the value output of the R&D portfolio. One of the NGR...
Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
Recent advances in super-resolution fluorescence microscopy based on single-molecule imaging have led to ~10 nm spatial resolution and exciting science. We are developing new approaches to a...
Despite the increasing number of effective anti-cancer therapies, successful treatment is limited by the development of drug resistance. While the contribution of genetic factors to drug res...
Unique physical, chemical, and optical phenomena arise when materials are confined to the nanoscale. We are accustomed to making observations for the behavior of living systems on a macrosco...
Auxin is a hormone crucial in nearly every aspect of plant growth and development. Advancing our understanding of auxin signaling in maize and other crop plants may provide needed tools for...
DATE: July 30, 2020 TIME: 10:00am PT Regenerative medicine has become a key focus worldwide and the number of stem cell, especially pluripotent stem cell (PSC)-based clinical trials are rapi...
Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
The cytolytic activity of Immune cells toward cancer cells is finely regulated through several pathways and receptors. Although end point assays have been routinely used to measure cell kill...
B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
Background: Acute liver injury (ALI) is characterised by hepatocyte death and liver inflammation. Macrophages play a pivotal role in ALI by phagocytosing dead cells and producing pro-regener...
Three dimensional (3D) spheroidal cell models have become a mainstay in life science research to provide the most in vivo-like environment. Performing media exchanges and washes with unattac...
Metastasis is the main cause of death in cancer patients and one of the most complex biological processes in human diseases (Hanahan et al., 2011). The development of therapies designed to f...
In this webinar we provide a detailed review of available methods for measuring cell proliferation, with a particular focus on recent assay innovations, including both 2D and 3D formats. Thi...
Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
One of the most common pathologically relevant mutated variants of ALK-2 (activin receptor-like kinase-2) has a point mutation (R206H) in its Ser/Thr kinase domain that promotes uncontrolled...
Natural light-harvesting systems, such as photosynthetic pigment-protein complexes, efficiently transfer energy through space with high efficiency. Ultimately, we would like to understand th...
DATE: August 6th, 2020 TIME: 10:00am PT In recent years Lilly has implemented a Next Generation Research (NGR) initiative to improve the value output of the R&D portfolio. One of the NGR...
Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
Recent advances in super-resolution fluorescence microscopy based on single-molecule imaging have led to ~10 nm spatial resolution and exciting science. We are developing new approaches to a...
Despite the increasing number of effective anti-cancer therapies, successful treatment is limited by the development of drug resistance. While the contribution of genetic factors to drug res...
Unique physical, chemical, and optical phenomena arise when materials are confined to the nanoscale. We are accustomed to making observations for the behavior of living systems on a macrosco...
Auxin is a hormone crucial in nearly every aspect of plant growth and development. Advancing our understanding of auxin signaling in maize and other crop plants may provide needed tools for...
DATE: July 30, 2020 TIME: 10:00am PT Regenerative medicine has become a key focus worldwide and the number of stem cell, especially pluripotent stem cell (PSC)-based clinical trials are rapi...
Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
The cytolytic activity of Immune cells toward cancer cells is finely regulated through several pathways and receptors. Although end point assays have been routinely used to measure cell kill...
B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
Background: Acute liver injury (ALI) is characterised by hepatocyte death and liver inflammation. Macrophages play a pivotal role in ALI by phagocytosing dead cells and producing pro-regener...
Three dimensional (3D) spheroidal cell models have become a mainstay in life science research to provide the most in vivo-like environment. Performing media exchanges and washes with unattac...
Metastasis is the main cause of death in cancer patients and one of the most complex biological processes in human diseases (Hanahan et al., 2011). The development of therapies designed to f...
In this webinar we provide a detailed review of available methods for measuring cell proliferation, with a particular focus on recent assay innovations, including both 2D and 3D formats. Thi...
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