Coronavirus is a group of RNA viruses that cause a variety of diseases in humans and other animals. COVID-19 is a new disease first identified in Wuhan China, caused by a new coronavirus that has not previously been seen in humans. In COVID-19, "CO" stands for corona, "VI" stands for virus, and D stands for disease and the 19 indicates it was first discovered in 2019. The virus is related (but is not the same) to the SARS-associated coronavirus that caused an outbreak of severe acute respiratory syndrome (SARS) in 2002-2003.
This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
The presentation will provide a review of major emerging zoonotic virus outbreaks from Hendra virus in 1994 in Australia to SARS-CoV-2 in China 2019 and our latest findings on bat biology an...
The University of Louisville Infectious Diseases Laboratory (IDL) is a high-complexity, CLIA-certified laboratory in Louisville, KY. The IDL adopted the Luminex ARIES® platform in 2016 f...
The COVID-19 pandemic continues to have a grip on worldwide health and global economics. Advancing molecular diagnostics is central to the diagnosis and prevention efforts surrounding the de...
When producing a quality vaccine, all manufacturers must confirm the purity as well as the stability of their formulation and final product. Sample quantity and measurement time are often th...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019 and has spread globally, causing a pandemic of respiratory illness designated coronavirus disease 20...
Cases and deaths continue to increase steadily in most states. The pace of increase is faster than we expected, leading us to revise upward IHME forecast of deaths and cases into the future....
To execute COVID-19 testing strategies effectively, labs need to procure reliable components of the workflow without interruption – from reagents to equipment and consumables at the sc...
Dynamic models of infectious disease systems are often used to study the epidemiological characteristics of disease outbreaks, the ecological mechanisms and environmental conditions affectin...
Learning Objectives: 1. Define SARS-CoV-2 immunity, antibody testing, and discuss what is known about the meaning of these tests 2. Identify challenges in doing research during social distan...
This talk goes over the importance of face masks as a pillar of COVID-19 pandemic control. First, we review the epidemiologic evidence for how face masks reduce COVID-19 transmission from st...
The fast spread and deadliness of SARS-CoV-2 has sparked much interest in understanding the underlying genomics and evolutionary patterns of this 30,000bp Coronavirus. Since the first report...
In this talk, Dr. Adalja will discuss the coronavirus family in general highlighting its history. Emphasis will be placed on why this viral family has pandemic potential. Learning Objectives...
Learning Objectives: 1. Learn what RNA and DNA vaccines are and why they are ideal vaccine strategies to respond rapidly to pandemics 2. Understand the key requirements of an effective vacci...
Next-Generation Sequencing (NGS) has been a key technology during the COVIID-19 pandemic and has helped researchers characterize the SARs-CoV-2 genome, perform strain-typing for molecular ep...
SARS-CoV-2 had spread with speed unknown in recent history across the globe, sickening >50M people and killing over 1M. By far the most of the severe cases and deaths were registered amon...
Antibody tests are important tools to assess the efficacy of vaccine candidates and to derive suitable vaccination modalities. High specificity and sensitivity are of great importance for th...
Date: November 13, 2020 10:00am PST, 1:00pm EST Coronavirus disease 2019 (COVID-19) is currently a global pandemic, but human immune responses to the virus remain poorly understood....
Cancer cells can acquire immune resistance resulting in a loss of immunosurveillance. Tumor cells can upregulate PDL-1 which binds to PD-1. This complex inhibits CD8 Tumor Infiltrating cells...
Date: November 9th, 2020 Time: 10:00am PDT SARS-CoV-2 continues to spread rapidly with critically ill patients admitted to the intensive care unit (ICU), where the mortality rate is reported...
Single-cell mass cytometry identifies mechanisms of resistance to immunotherapy in AML 6:30–7:00 am PDT Presented By: Shelley Herbrich, PhD Understanding CD19 negative relapse followin...
T cells are the adaptive immune system’s first responders to any virus, circulating in the blood to detect and quickly multiply to attack the virus, and also support the development of...
The COVID-19 pandemic has resulted in demand for population scale pathogen screening. The most sensitive and reliable method for detecting SARS-CoV-2 remains reverse transcription PCR (RT-PC...
There are an urgent need for antivirals to treat the newly emerged SARS-CoV-2. We set out to develop cell-based screens to repurpose existing drugs for use against SARS-CoV-2. Our goal was t...
This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
The presentation will provide a review of major emerging zoonotic virus outbreaks from Hendra virus in 1994 in Australia to SARS-CoV-2 in China 2019 and our latest findings on bat biology an...
The University of Louisville Infectious Diseases Laboratory (IDL) is a high-complexity, CLIA-certified laboratory in Louisville, KY. The IDL adopted the Luminex ARIES® platform in 2016 f...
The COVID-19 pandemic continues to have a grip on worldwide health and global economics. Advancing molecular diagnostics is central to the diagnosis and prevention efforts surrounding the de...
When producing a quality vaccine, all manufacturers must confirm the purity as well as the stability of their formulation and final product. Sample quantity and measurement time are often th...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019 and has spread globally, causing a pandemic of respiratory illness designated coronavirus disease 20...
Cases and deaths continue to increase steadily in most states. The pace of increase is faster than we expected, leading us to revise upward IHME forecast of deaths and cases into the future....
To execute COVID-19 testing strategies effectively, labs need to procure reliable components of the workflow without interruption – from reagents to equipment and consumables at the sc...
Dynamic models of infectious disease systems are often used to study the epidemiological characteristics of disease outbreaks, the ecological mechanisms and environmental conditions affectin...
Learning Objectives: 1. Define SARS-CoV-2 immunity, antibody testing, and discuss what is known about the meaning of these tests 2. Identify challenges in doing research during social distan...
This talk goes over the importance of face masks as a pillar of COVID-19 pandemic control. First, we review the epidemiologic evidence for how face masks reduce COVID-19 transmission from st...
The fast spread and deadliness of SARS-CoV-2 has sparked much interest in understanding the underlying genomics and evolutionary patterns of this 30,000bp Coronavirus. Since the first report...
In this talk, Dr. Adalja will discuss the coronavirus family in general highlighting its history. Emphasis will be placed on why this viral family has pandemic potential. Learning Objectives...
Learning Objectives: 1. Learn what RNA and DNA vaccines are and why they are ideal vaccine strategies to respond rapidly to pandemics 2. Understand the key requirements of an effective vacci...
Next-Generation Sequencing (NGS) has been a key technology during the COVIID-19 pandemic and has helped researchers characterize the SARs-CoV-2 genome, perform strain-typing for molecular ep...
SARS-CoV-2 had spread with speed unknown in recent history across the globe, sickening >50M people and killing over 1M. By far the most of the severe cases and deaths were registered amon...
Antibody tests are important tools to assess the efficacy of vaccine candidates and to derive suitable vaccination modalities. High specificity and sensitivity are of great importance for th...
Date: November 13, 2020 10:00am PST, 1:00pm EST Coronavirus disease 2019 (COVID-19) is currently a global pandemic, but human immune responses to the virus remain poorly understood....
Cancer cells can acquire immune resistance resulting in a loss of immunosurveillance. Tumor cells can upregulate PDL-1 which binds to PD-1. This complex inhibits CD8 Tumor Infiltrating cells...
Date: November 9th, 2020 Time: 10:00am PDT SARS-CoV-2 continues to spread rapidly with critically ill patients admitted to the intensive care unit (ICU), where the mortality rate is reported...
Single-cell mass cytometry identifies mechanisms of resistance to immunotherapy in AML 6:30–7:00 am PDT Presented By: Shelley Herbrich, PhD Understanding CD19 negative relapse followin...
T cells are the adaptive immune system’s first responders to any virus, circulating in the blood to detect and quickly multiply to attack the virus, and also support the development of...
The COVID-19 pandemic has resulted in demand for population scale pathogen screening. The most sensitive and reliable method for detecting SARS-CoV-2 remains reverse transcription PCR (RT-PC...
There are an urgent need for antivirals to treat the newly emerged SARS-CoV-2. We set out to develop cell-based screens to repurpose existing drugs for use against SARS-CoV-2. Our goal was t...
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