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    CRISPR

    CRISPR is an abbreviation of Clustered Regularly Interspaced Short Palindromic Repeats. The name was minted at a time when the origin and use of the interspacing subsequences were not known. At that time the CRISPRs were described as segments of prokaryotic DNA containing short, repetitive base sequences. In a palindromic repeat, the sequence of nucleotides is the same in both directions. Each repetition is followed by short segments of spacer DNA from previous exposures to foreign DNA (e.g., a virus or plasmid). Small clusters of cas (CRISPR-associated) genes are located next to CRISPR sequences.

    Trending News

    • JUN 25, 2021
      Genetics & Genomics
      Towards More Efficient Plant Engineering with CRISPR-Cas9 Gene Drive
      Towards More Efficient Plant Engineering with CRISPR-Cas9 Gene Drive
      Many people in the world don't have access to enough food. And while humans might find ways to adapt to a changing world ...
      Written By: Carmen Leitch
      1
      JUN 17, 2021
      Clinical & Molecular DX
      A RADICA Approach to Viral Diagnostics
      A RADICA Approach to Viral Diagnostics
        The COVID-19 pandemic has spurred a wave of new technologies for rapid viral diagnostics, given just how critical ...
      Written By: Tara Fernandes
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      JUN 07, 2021
      Cell & Molecular Biology
      Overcoming Challenges to Detect Apoptosis in 3D Cell Structures
      Overcoming Challenges to Detect Apoptosis in 3D Cell Structures
      Researchers are increasingly relying on cells grown in three-dimensional (3D) structures to help answer their research q ...
      Sponsored By: Promega
      1
      JUN 06, 2021
      Cell & Molecular Biology
      Caught in the Act of RNA Transcription
      Caught in the Act of RNA Transcription
      Researchers have now been able to capture an enzyme called RNA polymerase on video as it copies a DNA sequence into an R ...
      Written By: Carmen Leitch
      2
      MAY 26, 2021
      Plants & Animals
      Sterilizing Mosquitos with CRISPR to Control Disease
      Sterilizing Mosquitos with CRISPR to Control Disease
      By knocking out a gene in male mosquitos' testes, researchers demonstrate a powerful population control technique.
      Written By: Anne Medina
      1
      MAY 20, 2021
      Genetics & Genomics
      The rhAmpSeqâ„¢ CRISPR Analysis System for next-generation sequencing analysis of CRISPR edits
      The rhAmpSeqâ„¢ CRISPR Analysis System for next-generation sequencing analysis of CRISPR edits
      CRISPR genome editing generates double-stranded breaks (DSBs) in genomic DNA and is a targeted method by which to achiev ...
      Sponsored By: Integrated DNA Technologies, Inc.
      2
      MAY 12, 2021
      Health & Medicine
      Researchers Discover a New Genetic Disease that Prevents Antibody Formation
      Researchers Discover a New Genetic Disease that Prevents Antibody Formation
      Doctors at the Children's Hospital of Philadelphia discovered a new genetic disease that prevents B cell development.
      Written By: Caroline Wallace
      3
      MAY 06, 2021
      Clinical & Molecular DX
      Using Biology as Technology: A Paradigm Shift
      Using Biology as Technology: A Paradigm Shift
      Digital networks have changed the world by integrating into almost every aspect of our lives, but they have yet to direc ...
      Sponsored By: Cardea Bio
      1
      MAY 03, 2021
      Cell & Molecular Biology
      Are Retrons the Next CRISPR?
      Are Retrons the Next CRISPR?
      After being identified in the 1980s, it was thought that retrons were just an odd feature of some bacterial cells. But e ...
      Written By: Carmen Leitch
      2
      MAY 03, 2021
      Microbiology
      A New Bacterial Defense System is Discovered
      A New Bacterial Defense System is Discovered
      Most DNA that we're familiar with is found in cells in a double-stranded form. So, many years ago, scientists were intri ...
      Written By: Carmen Leitch
      4
      APR 18, 2021
      Cell & Molecular Biology
      Controlling the Epigenome with CRISPRoff & CRISPRon
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      Written By: Carmen Leitch
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      APR 09, 2021
      Cell & Molecular Biology
      CRISPR-SNP Chip Finds Point Mutations in DNA Without PCR
      CRISPR-SNP Chip Finds Point Mutations in DNA Without PCR
      Some diseases, like sickle-cell anemia and familial amyotrophic lateral sclerosis are due to errors in only a single let ...
      Written By: Carmen Leitch
      1
      APR 05, 2021
      Clinical & Molecular DX
      COVID Variants Can't Hide From CRISPR Diagnostic
      COVID Variants Can't Hide From CRISPR Diagnostic
      New variants of the coronaviruses have emerged over the course of the pandemic through the natural evolutionary process ...
      Written By: Tara Fernandes
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      APR 01, 2021
      Microbiology
      Mapping the Wild Microbiome to Search for Therapeutic Agents
      Mapping the Wild Microbiome to Search for Therapeutic Agents
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      MAR 09, 2021
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      A 'Plug-and-Play' CRISPR Therapy for Flu and COVID
      A 'Plug-and-Play' CRISPR Therapy for Flu and COVID
      Researchers have developed a CRISPR treatment that could potentially treat both viruses that cause COVID-19 and influenz ...
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      4
      FEB 28, 2021
      Genetics & Genomics
      CRISPR Advances Make the Gene Editor Specific to Tissues & Times
      CRISPR Advances Make the Gene Editor Specific to Tissues & Times
      Research scientists have to be able to manipulate molecules in cells to learn more about their function, what goes wrong ...
      Written By: Carmen Leitch
      1
      FEB 26, 2021
      Genetics & Genomics
      New Genes Can Form From 'Jumping" Gene Fusions
      New Genes Can Form From 'Jumping" Gene Fusions
      Some genes don't stay in the same place in the genome. Sometimes called jumping genes or transposons, this genetic mater ...
      Written By: Carmen Leitch
      3
      FEB 16, 2021
      Cell & Molecular Biology
      A Change in One Gene Might've Made Our Brains Uniquely Human
      A Change in One Gene Might've Made Our Brains Uniquely Human
      Stem cells can be used to create simplified versions of human organs called organoids, enabling researchers to study how ...
      Written By: Carmen Leitch
      1
      JAN 28, 2021
      Immunology
      Killers With a Hit on the Spike
      Killers With a Hit on the Spike
      Natural killer cells, or NK cells, are specialized immune cells of the innate immune system. Their job revolves around e ...
      Written By: Tara Fernandes
      1
      JAN 11, 2021
      Genetics & Genomics
      Treating Progeria With a CRISPR Technique
      Treating Progeria With a CRISPR Technique
      Hutchinson-Gilford progeria syndrome is a rare disorder that impacts around 400 people in the world. Many people have he ...
      Written By: Carmen Leitch
      1
      JAN 03, 2021
      Genetics & Genomics
      Exploiting Genetic Vulnerabilities in Cancer Cells
      Exploiting Genetic Vulnerabilities in Cancer Cells
      Genetic errors can drive cancer, often when critical genes like those that control cell division and proliferation becom ...
      Written By: Carmen Leitch
      1
      DEC 29, 2020
      Microbiology
      How CRISPR Can Help Create a Vaccine for a Common Parasite
      How CRISPR Can Help Create a Vaccine for a Common Parasite
      The parasite Toxoplasma gondii is thought to infect a third of the people on the planet as well as a wide range of other ...
      Written By: Carmen Leitch
      2
      DEC 23, 2020
      Clinical & Molecular DX
      Smartphone Device Uses CRISPR to Check for COVID
      Smartphone Device Uses CRISPR to Check for COVID
      Quick, portable, and ultrasensitive—a new smartphone test for COVID-19 checks all the boxes needed to get a handle ...
      Written By: Tara Fernandes
      1
      DEC 15, 2020
      Plants & Animals
      How an Insect Gained Its Wings
      How an Insect Gained Its Wings
      For decades, researchers have tried to understand how insect wings evolved. It seemed that none of the proposed explanat ...
      Written By: Carmen Leitch
      1
    JUN 25, 2021
    Genetics & Genomics
    Towards More Efficient Plant Engineering with CRISPR-Cas9 Gene Drive
    Towards More Efficient Plant Engineering with CRISPR-Cas9 Gene Drive
    Many people in the world don't have access to enough food. And while humans might find ways to adapt to a changing world ...
    Written By: Carmen Leitch
    1
    JUN 17, 2021
    Clinical & Molecular DX
    A RADICA Approach to Viral Diagnostics
    A RADICA Approach to Viral Diagnostics
      The COVID-19 pandemic has spurred a wave of new technologies for rapid viral diagnostics, given just how critical ...
    Written By: Tara Fernandes
    1
    JUN 07, 2021
    Cell & Molecular Biology
    Overcoming Challenges to Detect Apoptosis in 3D Cell Structures
    Overcoming Challenges to Detect Apoptosis in 3D Cell Structures
    Researchers are increasingly relying on cells grown in three-dimensional (3D) structures to help answer their research q ...
    Sponsored By: Promega
    1
    JUN 06, 2021
    Cell & Molecular Biology
    Caught in the Act of RNA Transcription
    Caught in the Act of RNA Transcription
    Researchers have now been able to capture an enzyme called RNA polymerase on video as it copies a DNA sequence into an R ...
    Written By: Carmen Leitch
    2
    MAY 26, 2021
    Plants & Animals
    Sterilizing Mosquitos with CRISPR to Control Disease
    Sterilizing Mosquitos with CRISPR to Control Disease
    By knocking out a gene in male mosquitos' testes, researchers demonstrate a powerful population control technique.
    Written By: Anne Medina
    1
     
     
  • MAY 20, 2021
    Genetics & Genomics
    The rhAmpSeqâ„¢ CRISPR Analysis System for next-generation sequencing analysis of CRISPR edits
    The rhAmpSeqâ„¢ CRISPR Analysis System for next-generation sequencing analysis of CRISPR edits
    CRISPR genome editing generates double-stranded breaks (DSBs) in genomic DNA and is a targeted method by which to achiev ...
    Sponsored By: Integrated DNA Technologies, Inc.
    2
    MAY 12, 2021
    Health & Medicine
    Researchers Discover a New Genetic Disease that Prevents Antibody Formation
    Researchers Discover a New Genetic Disease that Prevents Antibody Formation
    Doctors at the Children's Hospital of Philadelphia discovered a new genetic disease that prevents B cell development.
    Written By: Caroline Wallace
    3
    MAY 06, 2021
    Clinical & Molecular DX
    Using Biology as Technology: A Paradigm Shift
    Using Biology as Technology: A Paradigm Shift
    Digital networks have changed the world by integrating into almost every aspect of our lives, but they have yet to direc ...
    Sponsored By: Cardea Bio
    1
    MAY 03, 2021
    Cell & Molecular Biology
    Are Retrons the Next CRISPR?
    Are Retrons the Next CRISPR?
    After being identified in the 1980s, it was thought that retrons were just an odd feature of some bacterial cells. But e ...
    Written By: Carmen Leitch
    2
    MAY 03, 2021
    Microbiology
    A New Bacterial Defense System is Discovered
    A New Bacterial Defense System is Discovered
    Most DNA that we're familiar with is found in cells in a double-stranded form. So, many years ago, scientists were intri ...
    Written By: Carmen Leitch
    4
     
     
  • APR 18, 2021
    Cell & Molecular Biology
    Controlling the Epigenome with CRISPRoff & CRISPRon
    Controlling the Epigenome with CRISPRoff & CRISPRon
    Some parts of the genome are simple; many genes encode for proteins, and if there is an error in one of those protein-co ...
    Written By: Carmen Leitch
    1
    APR 09, 2021
    Cell & Molecular Biology
    CRISPR-SNP Chip Finds Point Mutations in DNA Without PCR
    CRISPR-SNP Chip Finds Point Mutations in DNA Without PCR
    Some diseases, like sickle-cell anemia and familial amyotrophic lateral sclerosis are due to errors in only a single let ...
    Written By: Carmen Leitch
    1
    APR 05, 2021
    Clinical & Molecular DX
    COVID Variants Can't Hide From CRISPR Diagnostic
    COVID Variants Can't Hide From CRISPR Diagnostic
    New variants of the coronaviruses have emerged over the course of the pandemic through the natural evolutionary process ...
    Written By: Tara Fernandes
    1
    APR 01, 2021
    Microbiology
    Mapping the Wild Microbiome to Search for Therapeutic Agents
    Mapping the Wild Microbiome to Search for Therapeutic Agents
    Many people think of bacteria as disgusting germs, but there are plenty of important bacterial species that provide us w ...
    Written By: Carmen Leitch
    1
    MAR 09, 2021
    Immunology
    A 'Plug-and-Play' CRISPR Therapy for Flu and COVID
    A 'Plug-and-Play' CRISPR Therapy for Flu and COVID
    Researchers have developed a CRISPR treatment that could potentially treat both viruses that cause COVID-19 and influenz ...
    Written By: Tara Fernandes
    4
     
     
  • FEB 28, 2021
    Genetics & Genomics
    CRISPR Advances Make the Gene Editor Specific to Tissues & Times
    CRISPR Advances Make the Gene Editor Specific to Tissues & Times
    Research scientists have to be able to manipulate molecules in cells to learn more about their function, what goes wrong ...
    Written By: Carmen Leitch
    1
    FEB 26, 2021
    Genetics & Genomics
    New Genes Can Form From 'Jumping" Gene Fusions
    New Genes Can Form From 'Jumping" Gene Fusions
    Some genes don't stay in the same place in the genome. Sometimes called jumping genes or transposons, this genetic mater ...
    Written By: Carmen Leitch
    3
    FEB 16, 2021
    Cell & Molecular Biology
    A Change in One Gene Might've Made Our Brains Uniquely Human
    A Change in One Gene Might've Made Our Brains Uniquely Human
    Stem cells can be used to create simplified versions of human organs called organoids, enabling researchers to study how ...
    Written By: Carmen Leitch
    1
    JAN 28, 2021
    Immunology
    Killers With a Hit on the Spike
    Killers With a Hit on the Spike
    Natural killer cells, or NK cells, are specialized immune cells of the innate immune system. Their job revolves around e ...
    Written By: Tara Fernandes
    1
    JAN 11, 2021
    Genetics & Genomics
    Treating Progeria With a CRISPR Technique
    Treating Progeria With a CRISPR Technique
    Hutchinson-Gilford progeria syndrome is a rare disorder that impacts around 400 people in the world. Many people have he ...
    Written By: Carmen Leitch
    1
     
     
  • JAN 03, 2021
    Genetics & Genomics
    Exploiting Genetic Vulnerabilities in Cancer Cells
    Exploiting Genetic Vulnerabilities in Cancer Cells
    Genetic errors can drive cancer, often when critical genes like those that control cell division and proliferation becom ...
    Written By: Carmen Leitch
    1
    DEC 29, 2020
    Microbiology
    How CRISPR Can Help Create a Vaccine for a Common Parasite
    How CRISPR Can Help Create a Vaccine for a Common Parasite
    The parasite Toxoplasma gondii is thought to infect a third of the people on the planet as well as a wide range of other ...
    Written By: Carmen Leitch
    2
    DEC 23, 2020
    Clinical & Molecular DX
    Smartphone Device Uses CRISPR to Check for COVID
    Smartphone Device Uses CRISPR to Check for COVID
    Quick, portable, and ultrasensitive—a new smartphone test for COVID-19 checks all the boxes needed to get a handle ...
    Written By: Tara Fernandes
    1
    DEC 15, 2020
    Plants & Animals
    How an Insect Gained Its Wings
    How an Insect Gained Its Wings
    For decades, researchers have tried to understand how insect wings evolved. It seemed that none of the proposed explanat ...
    Written By: Carmen Leitch
    1
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