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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • AUG 08, 2019
      Drug Discovery & Development
      Gel Reduces Surgical Scarring
      Gel Reduces Surgical Scarring
      Scientists have found that spraying a gel on the internal tissues of animal post-surgery has significantly reduced scarr ...
      Written By: Nouran Amin
      1
      AUG 07, 2019
      Drug Discovery & Development
      Chemotherapeutics react differently to radiation
      Chemotherapeutics react differently to radiation
      Patients with various types of cancer are almost always treated with a combination of chemotherapy and radiotherapy. In ...
      Written By: Nouran Amin
      1
      AUG 06, 2019
      Cell & Molecular Biology
      Relieving a Mechanism That Could Underlie as Many as 20 Rare Disorders
      Relieving a Mechanism That Could Underlie as Many as 20 Rare Disorders
      Toxic proteinopathies are a group of inherited diseases that are caused when improperly folded proteins accumulate in th ...
      Written By: Carmen Leitch
      2
      AUG 04, 2019
      Drug Discovery & Development
      Does Microdosing Really Boost Productivity and Creativity?
      Does Microdosing Really Boost Productivity and Creativity?
      Microdosing is the practice of ingesting very low doses of psychedelic substances, typically a twentieth of a recreation ...
      Written By: Annie Lennon
      1
      AUG 04, 2019
      Cancer
      The anti-cancer flower
      The anti-cancer flower
      Perhaps you have heard of feverfew, a quite common flowering plant that graces many home gardens. Its cute white petals ...
      Written By: Kathryn DeMuth Sullivan
      2
      AUG 02, 2019
      Drug Discovery & Development
      Can Ecstasy Treat PTSD and Depression?
      Can Ecstasy Treat PTSD and Depression?
      Ecstasy, also known as MDMA or “molly”, is a well-known substance known to induce feelings of euphoria and b ...
      Written By: Annie Lennon
      1
      AUG 01, 2019
      Drug Discovery & Development
      Aspirin Usage Improves Liver Function After Embolization Treatment
      Aspirin Usage Improves Liver Function After Embolization Treatment
      Aspirin usage has been under scrutiny in recent research. But now, studies are bringing aspirin therapy in renewed light ...
      Written By: Nouran Amin
      1
      AUG 01, 2019
      Drug Discovery & Development
      Novel Therapy Shows Promise for Acute Migraines
      Novel Therapy Shows Promise for Acute Migraines
      In a study published in The New England Journal of Medicine, a novel drug, by the name of rimegepant, was found to elimi ...
      Written By: Nouran Amin
      1
      JUL 31, 2019
      Health & Medicine
      Ketamine is not an opioid, and treats depression in a novel way
      Ketamine is not an opioid, and treats depression in a novel way
      In March, the U.S. Food and Drug Administration approved ketamine nasal spray to treat depression. Ketamine has gotten a ...
      Written By: Dr. Nina Lichtenberg
      1
      JUL 30, 2019
      Drug Discovery & Development
      Treating Drug-Resistant Acute Lymphoblastic Leukemia
      Treating Drug-Resistant Acute Lymphoblastic Leukemia
      New therapeutics may have helped improve survival rates for acute lymphoblastic leukemia patients but some patients stil ...
      Written By: Nouran Amin
      1
      JUL 29, 2019
      Drug Discovery & Development
      Compound Found in Wine May Treat Anxiety
      Compound Found in Wine May Treat Anxiety
      A study published in the journal Neuropharmacology claims that a compound found in red wine could be used as therapeutic ...
      Written By: Nouran Amin
      1
      JUL 29, 2019
      Drug Discovery & Development
      Medications Used for Atrial fibrillation May Increase Falls
      Medications Used for Atrial fibrillation May Increase Falls
      Falls among older adults are a growing health concern that often lead to injury, hospitalization, and other severe compl ...
      Written By: Nouran Amin
      1
      JUL 28, 2019
      Genetics & Genomics
      New Drug Targets for Lung Cancer Identified
      New Drug Targets for Lung Cancer Identified
      Researchers at the Salk Institute have now learned why certain genetic mutations lead to cancer growth.
      Written By: Carmen Leitch
      1
      JUL 28, 2019
      Cell & Molecular Biology
      Revealing More About Aging on the Cellular Level
      Revealing More About Aging on the Cellular Level
      Our bodies are made up of trillions and cells, and millions of them die every day.
      Written By: Carmen Leitch
      1
      JUL 25, 2019
      Microbiology
      The Therapeutic Potential of Bacteriophages
      The Therapeutic Potential of Bacteriophages
      There are vast numbers of viruses in our world, and some of them, called bacteriophages, only infect bacteria.
      Written By: Carmen Leitch
      1
      JUL 24, 2019
      Drug Discovery & Development
      HIV Therapeutics Places Risk of Neural Tube Defects
      HIV Therapeutics Places Risk of Neural Tube Defects
      In a study published in the New England Journal of Medicine, women taking an HIV therapeutic drug containing dolutegravi ...
      Written By: Nouran Amin
      1
      JUL 24, 2019
      Drug Discovery & Development
      Understanding The Anti-Malarial Drug Primaquine (PQ)
      Understanding The Anti-Malarial Drug Primaquine (PQ)
      Scientists at the Liverpool School of Tropical Medicine (LSTM) have advanced their experiments to understand the mode of ...
      Written By: Nouran Amin
      1
      JUL 23, 2019
      Drug Discovery & Development
      Maintenance of Shelf-Stable Drugs
      Maintenance of Shelf-Stable Drugs
      In a study published in the Proceedings of the National Academy of Sciences, scientists have designed a mathematical mod ...
      Written By: Nouran Amin
      1
      JUL 23, 2019
      Microbiology
      Specific Gut Microbes Slow ALS Progression in a Mouse Model
      Specific Gut Microbes Slow ALS Progression in a Mouse Model
      We've come a long way in the five years since the ice bucket challenge drew attention to amyotrophic lateral sclerosis ( ...
      Written By: Carmen Leitch
      1
      JUL 19, 2019
      Drug Discovery & Development
      Anti-cancer Drug Disguises as Fat
      Anti-cancer Drug Disguises as Fat
      According to a study published in the Journal of the American Chemical Society (JACS), a new drug-delivery system disgui ...
      Written By: Nouran Amin
      2
      JUL 19, 2019
      Clinical & Molecular DX
      Possible Non-Hormonal Treatment For Endometriosis On Horizon
      Possible Non-Hormonal Treatment For Endometriosis On Horizon
      With over 200,000 cases reported annually, endometriosis is a big concern in women’s health. Scientists don’ ...
      Written By: Abbie Arce
      1
      JUL 17, 2019
      Drug Discovery & Development
      The Composition of Cerebrospinal Fluid in MS patients Could Be The Key To Treatments That Halt Progression
      The Composition of Cerebrospinal Fluid in MS patients Could Be The Key To Treatments That Halt Progression
      The range of disability for individuals living with multiple sclerosis (MS) varies significantly depending on the relaps ...
      Written By: Nouran Amin
      1
      JUL 14, 2019
      Cell & Molecular Biology
      Scratching a Chronic Itch
      Scratching a Chronic Itch
      There are many potential reasons why skin might itch, but this annoying condition can significantly impact quality of li ...
      Written By: Carmen Leitch
      2
      JUL 13, 2019
      Cell & Molecular Biology
      Learning More About the Causes of Endometriosis Pain
      Learning More About the Causes of Endometriosis Pain
      Endometriosis can be an extremely painful disorder that significantly impacts quality of life.
      Written By: Carmen Leitch
      1
    AUG 08, 2019
    Drug Discovery & Development
    Gel Reduces Surgical Scarring
    Gel Reduces Surgical Scarring
    Scientists have found that spraying a gel on the internal tissues of animal post-surgery has significantly reduced scarr ...
    Written By: Nouran Amin
    1
    AUG 07, 2019
    Drug Discovery & Development
    Chemotherapeutics react differently to radiation
    Chemotherapeutics react differently to radiation
    Patients with various types of cancer are almost always treated with a combination of chemotherapy and radiotherapy. In ...
    Written By: Nouran Amin
    1
    AUG 06, 2019
    Cell & Molecular Biology
    Relieving a Mechanism That Could Underlie as Many as 20 Rare Disorders
    Relieving a Mechanism That Could Underlie as Many as 20 Rare Disorders
    Toxic proteinopathies are a group of inherited diseases that are caused when improperly folded proteins accumulate in th ...
    Written By: Carmen Leitch
    2
    AUG 04, 2019
    Drug Discovery & Development
    Does Microdosing Really Boost Productivity and Creativity?
    Does Microdosing Really Boost Productivity and Creativity?
    Microdosing is the practice of ingesting very low doses of psychedelic substances, typically a twentieth of a recreation ...
    Written By: Annie Lennon
    1
    AUG 04, 2019
    Cancer
    The anti-cancer flower
    The anti-cancer flower
    Perhaps you have heard of feverfew, a quite common flowering plant that graces many home gardens. Its cute white petals ...
    Written By: Kathryn DeMuth Sullivan
    2
     
     
  • AUG 02, 2019
    Drug Discovery & Development
    Can Ecstasy Treat PTSD and Depression?
    Can Ecstasy Treat PTSD and Depression?
    Ecstasy, also known as MDMA or “molly”, is a well-known substance known to induce feelings of euphoria and b ...
    Written By: Annie Lennon
    1
    AUG 01, 2019
    Drug Discovery & Development
    Aspirin Usage Improves Liver Function After Embolization Treatment
    Aspirin Usage Improves Liver Function After Embolization Treatment
    Aspirin usage has been under scrutiny in recent research. But now, studies are bringing aspirin therapy in renewed light ...
    Written By: Nouran Amin
    1
    AUG 01, 2019
    Drug Discovery & Development
    Novel Therapy Shows Promise for Acute Migraines
    Novel Therapy Shows Promise for Acute Migraines
    In a study published in The New England Journal of Medicine, a novel drug, by the name of rimegepant, was found to elimi ...
    Written By: Nouran Amin
    1
    JUL 31, 2019
    Health & Medicine
    Ketamine is not an opioid, and treats depression in a novel way
    Ketamine is not an opioid, and treats depression in a novel way
    In March, the U.S. Food and Drug Administration approved ketamine nasal spray to treat depression. Ketamine has gotten a ...
    Written By: Dr. Nina Lichtenberg
    1
    JUL 30, 2019
    Drug Discovery & Development
    Treating Drug-Resistant Acute Lymphoblastic Leukemia
    Treating Drug-Resistant Acute Lymphoblastic Leukemia
    New therapeutics may have helped improve survival rates for acute lymphoblastic leukemia patients but some patients stil ...
    Written By: Nouran Amin
    1
     
     
  • JUL 29, 2019
    Drug Discovery & Development
    Compound Found in Wine May Treat Anxiety
    Compound Found in Wine May Treat Anxiety
    A study published in the journal Neuropharmacology claims that a compound found in red wine could be used as therapeutic ...
    Written By: Nouran Amin
    1
    JUL 29, 2019
    Drug Discovery & Development
    Medications Used for Atrial fibrillation May Increase Falls
    Medications Used for Atrial fibrillation May Increase Falls
    Falls among older adults are a growing health concern that often lead to injury, hospitalization, and other severe compl ...
    Written By: Nouran Amin
    1
    JUL 28, 2019
    Genetics & Genomics
    New Drug Targets for Lung Cancer Identified
    New Drug Targets for Lung Cancer Identified
    Researchers at the Salk Institute have now learned why certain genetic mutations lead to cancer growth.
    Written By: Carmen Leitch
    1
    JUL 28, 2019
    Cell & Molecular Biology
    Revealing More About Aging on the Cellular Level
    Revealing More About Aging on the Cellular Level
    Our bodies are made up of trillions and cells, and millions of them die every day.
    Written By: Carmen Leitch
    1
    JUL 25, 2019
    Microbiology
    The Therapeutic Potential of Bacteriophages
    The Therapeutic Potential of Bacteriophages
    There are vast numbers of viruses in our world, and some of them, called bacteriophages, only infect bacteria.
    Written By: Carmen Leitch
    1
     
     
  • JUL 24, 2019
    Drug Discovery & Development
    HIV Therapeutics Places Risk of Neural Tube Defects
    HIV Therapeutics Places Risk of Neural Tube Defects
    In a study published in the New England Journal of Medicine, women taking an HIV therapeutic drug containing dolutegravi ...
    Written By: Nouran Amin
    1
    JUL 24, 2019
    Drug Discovery & Development
    Understanding The Anti-Malarial Drug Primaquine (PQ)
    Understanding The Anti-Malarial Drug Primaquine (PQ)
    Scientists at the Liverpool School of Tropical Medicine (LSTM) have advanced their experiments to understand the mode of ...
    Written By: Nouran Amin
    1
    JUL 23, 2019
    Drug Discovery & Development
    Maintenance of Shelf-Stable Drugs
    Maintenance of Shelf-Stable Drugs
    In a study published in the Proceedings of the National Academy of Sciences, scientists have designed a mathematical mod ...
    Written By: Nouran Amin
    1
    JUL 23, 2019
    Microbiology
    Specific Gut Microbes Slow ALS Progression in a Mouse Model
    Specific Gut Microbes Slow ALS Progression in a Mouse Model
    We've come a long way in the five years since the ice bucket challenge drew attention to amyotrophic lateral sclerosis ( ...
    Written By: Carmen Leitch
    1
    JUL 19, 2019
    Drug Discovery & Development
    Anti-cancer Drug Disguises as Fat
    Anti-cancer Drug Disguises as Fat
    According to a study published in the Journal of the American Chemical Society (JACS), a new drug-delivery system disgui ...
    Written By: Nouran Amin
    2
     
     
  • JUL 19, 2019
    Clinical & Molecular DX
    Possible Non-Hormonal Treatment For Endometriosis On Horizon
    Possible Non-Hormonal Treatment For Endometriosis On Horizon
    With over 200,000 cases reported annually, endometriosis is a big concern in women’s health. Scientists don’ ...
    Written By: Abbie Arce
    1
    JUL 17, 2019
    Drug Discovery & Development
    The Composition of Cerebrospinal Fluid in MS patients Could Be The Key To Treatments That Halt Progression
    The Composition of Cerebrospinal Fluid in MS patients Could Be The Key To Treatments That Halt Progression
    The range of disability for individuals living with multiple sclerosis (MS) varies significantly depending on the relaps ...
    Written By: Nouran Amin
    1
    JUL 14, 2019
    Cell & Molecular Biology
    Scratching a Chronic Itch
    Scratching a Chronic Itch
    There are many potential reasons why skin might itch, but this annoying condition can significantly impact quality of li ...
    Written By: Carmen Leitch
    2
    JUL 13, 2019
    Cell & Molecular Biology
    Learning More About the Causes of Endometriosis Pain
    Learning More About the Causes of Endometriosis Pain
    Endometriosis can be an extremely painful disorder that significantly impacts quality of life.
    Written By: Carmen Leitch
    1
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