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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • JAN 25, 2020
      Drug Discovery & Development
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      Taking Psychedelics Improves Mood, says Yale Researchers
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      JAN 23, 2020
      Cell & Molecular Biology
      Scientists Engineer Venom-Producing Organoids
      Scientists Engineer Venom-Producing Organoids
      Snake venom is also a source of therapeutics, and a potential source of new medicines.
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      JAN 22, 2020
      Cannabis Sciences
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      JAN 21, 2020
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      Medical Marijuana Ineffective for Long Term Pain Management
      Medical Marijuana Ineffective for Long Term Pain Management
      Medicinal cannabis may not as effective as once thought as a solution for sleep problems for those with chronic pain in ...
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      JAN 21, 2020
      Drug Discovery & Development
      Drug Targets Gastrointestinal Cancer
      Drug Targets Gastrointestinal Cancer
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      JAN 21, 2020
      Cancer
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      A gene for leukemia triggers the growth of stem blood cells
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      JAN 21, 2020
      Cell & Molecular Biology
      Repurposing Existing Drugs to Treat Cancer
      Repurposing Existing Drugs to Treat Cancer
      Drugs have to be rigorously tested before they can be offered to patients, so it can be much easier to find more than on ...
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      JAN 20, 2020
      Cancer
      Did you know these non-cancer drugs can also fight cancer?
      Did you know these non-cancer drugs can also fight cancer?
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      JAN 20, 2020
      Cell & Molecular Biology
      Using Modified Red Blood Cells As a Drug Delivery System
      Using Modified Red Blood Cells As a Drug Delivery System
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      JAN 18, 2020
      Drug Discovery & Development
      Drug Combo Targets Osteoarthritis
      Drug Combo Targets Osteoarthritis
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      JAN 17, 2020
      Cancer
      Could salt nanoparticles kill cancer?
      Could salt nanoparticles kill cancer?
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      JAN 16, 2020
      Health & Medicine
      Babies in Africa Receive World's First Malaria Vaccine
      Babies in Africa Receive World's First Malaria Vaccine
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      JAN 16, 2020
      Cancer
      FLASH proton therapy: faster and more effective
      FLASH proton therapy: faster and more effective
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      JAN 16, 2020
      Drug Discovery & Development
      Fatty Acid Supplement Repairs Brain After Stroke in Mice
      Fatty Acid Supplement Repairs Brain After Stroke in Mice
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      JAN 15, 2020
      Drug Discovery & Development
      FDA Approves Drugs Faster than Ever- But is That Good?
      FDA Approves Drugs Faster than Ever- But is That Good?
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      JAN 15, 2020
      Drug Discovery & Development
      Treating Malaria: Molecular Understanding of Drug Interactions
      Treating Malaria: Molecular Understanding of Drug Interactions
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      2
      JAN 15, 2020
      Drug Discovery & Development
      A New Drug Target for Substance Abuse
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      JAN 15, 2020
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      Acid-Reflux Drugs May Negatively Impact Breast Cancer Survivors
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      JAN 15, 2020
      Cancer
      Hope for patients with AML
      Hope for patients with AML
      Research published recently in the medical journal EMBO Molecular Medicine brings hope for leukemia patients with a repo ...
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      1
      JAN 14, 2020
      Cancer
      Could the flu vaccine shrink cancer tumors?
      Could the flu vaccine shrink cancer tumors?
      If you’ve been to the doctor recently, you’ve probably been asked if you want a flu shot this year. The flu ...
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      2
      JAN 14, 2020
      Drug Discovery & Development
      Promising Treatment for Dementia: Antibiotics
      Promising Treatment for Dementia: Antibiotics
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      JAN 14, 2020
      Genetics & Genomics
      Genetic Study Reveals Drug Targets for Several Diseases
      Genetic Study Reveals Drug Targets for Several Diseases
      Some genetic mutations are due to a change in only one base of the genetic code, while others involve large regions of t ...
      Written By: Carmen Leitch
      1
      JAN 14, 2020
      Drug Discovery & Development
      Can Silica Treat Obesity and Diabetes?
      Can Silica Treat Obesity and Diabetes?
      Silica particles, specifically ‘mesoporous silica particles (MSPs)’ are engineered molecular traps that may ...
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      JAN 13, 2020
      Cancer
      The anti-cancer properties of bitter melon
      The anti-cancer properties of bitter melon
      New research published in the journal Cell Communication and Signaling suggests that bitter melon, also known as bitter ...
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    JAN 25, 2020
    Drug Discovery & Development
    Taking Psychedelics Improves Mood, says Yale Researchers
    Taking Psychedelics Improves Mood, says Yale Researchers
    Psychedelics have long been known for their potential to enable deep reflection and modulate people’s moods. But e ...
    Written By: Annie Lennon
    2
    JAN 23, 2020
    Cell & Molecular Biology
    Scientists Engineer Venom-Producing Organoids
    Scientists Engineer Venom-Producing Organoids
    Snake venom is also a source of therapeutics, and a potential source of new medicines.
    Written By: Carmen Leitch
    1
    JAN 22, 2020
    Cannabis Sciences
    Antibiotic Properties Found in Cannabis Compound
    Antibiotic Properties Found in Cannabis Compound
    The World Health Organization has identified antibiotic resistance, when bacteria no longer respond to antibiotics, as o ...
    Written By: Annie Lennon
    3
    JAN 21, 2020
    Cannabis Sciences
    Medical Marijuana Ineffective for Long Term Pain Management
    Medical Marijuana Ineffective for Long Term Pain Management
    Medicinal cannabis may not as effective as once thought as a solution for sleep problems for those with chronic pain in ...
    Written By: Annie Lennon
    1
    JAN 21, 2020
    Drug Discovery & Development
    Drug Targets Gastrointestinal Cancer
    Drug Targets Gastrointestinal Cancer
    The FDA has recently approved Ayvakit (avapritinib) for the treatment of unresectable and metastatic gastrointestinal st ...
    Written By: Nouran Amin
    1
     
     
  • JAN 21, 2020
    Cancer
    A gene for leukemia triggers the growth of stem blood cells
    A gene for leukemia triggers the growth of stem blood cells
    New research from the University of Colorado Cancer Center has identified a way to make hematopoietic stem cells from a ...
    Written By: Kathryn DeMuth Sullivan
    1
    JAN 21, 2020
    Cell & Molecular Biology
    Repurposing Existing Drugs to Treat Cancer
    Repurposing Existing Drugs to Treat Cancer
    Drugs have to be rigorously tested before they can be offered to patients, so it can be much easier to find more than on ...
    Written By: Carmen Leitch
    1
    JAN 20, 2020
    Cancer
    Did you know these non-cancer drugs can also fight cancer?
    Did you know these non-cancer drugs can also fight cancer?
    A study from MIT. Harvard and the Dana-Farber Cancer Institute has concluded that almost 50 existing non-oncological dru ...
    Written By: Kathryn DeMuth Sullivan
    2
    JAN 20, 2020
    Cell & Molecular Biology
    Using Modified Red Blood Cells As a Drug Delivery System
    Using Modified Red Blood Cells As a Drug Delivery System
    For a drug to be effective, it has to get to the right place to exert its impact.
    Written By: Carmen Leitch
    2
    JAN 18, 2020
    Drug Discovery & Development
    Drug Combo Targets Osteoarthritis
    Drug Combo Targets Osteoarthritis
    Individuals suffering from osteoarthritis often face challenges of limited treatment options mainly pain relievers or jo ...
    Written By: Nouran Amin
    2
     
     
  • JAN 17, 2020
    Cancer
    Could salt nanoparticles kill cancer?
    Could salt nanoparticles kill cancer?
    Could salt be the key to killing cancer cells? A new study published in Advanced Materials reports success in using sodi ...
    Written By: Kathryn DeMuth Sullivan
    1 1
    JAN 16, 2020
    Health & Medicine
    Babies in Africa Receive World's First Malaria Vaccine
    Babies in Africa Receive World's First Malaria Vaccine
    Would you accept a vaccine that was only 40% effective? For those at risk of malaria, the answer is likely a resounding, ...
    Written By: Tiffany Dazet
    1
    JAN 16, 2020
    Cancer
    FLASH proton therapy: faster and more effective
    FLASH proton therapy: faster and more effective
    A new technique called FLASH proposes a new type of radiation therapy. The technique is composed of an ultra-high dose r ...
    Written By: Kathryn DeMuth Sullivan
    3
    JAN 16, 2020
    Drug Discovery & Development
    Fatty Acid Supplement Repairs Brain After Stroke in Mice
    Fatty Acid Supplement Repairs Brain After Stroke in Mice
    Researchers have found that supplements containing short chain fatty acids (SCFAs) may be able to help the brain recover ...
    Written By: Annie Lennon
    1
    JAN 15, 2020
    Drug Discovery & Development
    FDA Approves Drugs Faster than Ever- But is That Good?
    FDA Approves Drugs Faster than Ever- But is That Good?
    The Food and Drug Administration (FDA) is approving new drugs for patients on less and less evidence thanks to special p ...
    Written By: Annie Lennon
    1
     
     
  • JAN 15, 2020
    Drug Discovery & Development
    Treating Malaria: Molecular Understanding of Drug Interactions
    Treating Malaria: Molecular Understanding of Drug Interactions
    Crystallization is a process central to drug development that despite centuries of facilitating a particular method, che ...
    Written By: Nouran Amin
    2
    JAN 15, 2020
    Drug Discovery & Development
    A New Drug Target for Substance Abuse
    A New Drug Target for Substance Abuse
    Research carried out by the University of Minnesota Medical School indicates a new drug target for treating a drug addic ...
    Written By: Nouran Amin
    1
    JAN 15, 2020
    Drug Discovery & Development
    Acid-Reflux Drugs May Negatively Impact Breast Cancer Survivors
    Acid-Reflux Drugs May Negatively Impact Breast Cancer Survivors
    Many of us have taken some form of an acid-reflux drug—especially after a meal that causes discomfort. However, no ...
    Written By: Nouran Amin
    1
    JAN 15, 2020
    Cancer
    Hope for patients with AML
    Hope for patients with AML
    Research published recently in the medical journal EMBO Molecular Medicine brings hope for leukemia patients with a repo ...
    Written By: Kathryn DeMuth Sullivan
    1
    JAN 14, 2020
    Cancer
    Could the flu vaccine shrink cancer tumors?
    Could the flu vaccine shrink cancer tumors?
    If you’ve been to the doctor recently, you’ve probably been asked if you want a flu shot this year. The flu ...
    Written By: Kathryn DeMuth Sullivan
    2
     
     
  • JAN 14, 2020
    Drug Discovery & Development
    Promising Treatment for Dementia: Antibiotics
    Promising Treatment for Dementia: Antibiotics
    A class of antibiotics, known as the ‘aminoglycosides’ may serve as a promising treatment for frontotemporal ...
    Written By: Nouran Amin
    1
    JAN 14, 2020
    Genetics & Genomics
    Genetic Study Reveals Drug Targets for Several Diseases
    Genetic Study Reveals Drug Targets for Several Diseases
    Some genetic mutations are due to a change in only one base of the genetic code, while others involve large regions of t ...
    Written By: Carmen Leitch
    1
    JAN 14, 2020
    Drug Discovery & Development
    Can Silica Treat Obesity and Diabetes?
    Can Silica Treat Obesity and Diabetes?
    Silica particles, specifically ‘mesoporous silica particles (MSPs)’ are engineered molecular traps that may ...
    Written By: Nouran Amin
    1
    JAN 13, 2020
    Cancer
    The anti-cancer properties of bitter melon
    The anti-cancer properties of bitter melon
    New research published in the journal Cell Communication and Signaling suggests that bitter melon, also known as bitter ...
    Written By: Kathryn DeMuth Sullivan
    1 1
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