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Drug Discovery
Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
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JAN 13, 2020Drug Discovery & Development
Currently Alzheimer’s disease is thought to affect around 50 million people around the world, with this figure dou ...Written By: Annie LennonJAN 12, 2020Cell & Molecular Biology
Altering two signaling pathways extended the lives of a research model called C elegans by an astonishing 500 percent.Written By: Carmen LeitchJAN 06, 2020Drug Discovery & Development
A study published by PNAS explains breakthrough research around designing drugs that target C. diff bacterial infections ...Written By: Nouran AminJAN 04, 2020Cardiology
Heart disease is the top killer in the Western world. This is partially because, if one manages to survive an initial he ...Written By: Annie LennonJAN 03, 2020Drug Discovery & Development
Previously considered to be narcotic, and under tight regulation as an illicit drug for decades, research from recent ye ...Written By: Annie LennonJAN 03, 2020Drug Discovery & Development
Researchers from Georgetown University have found that combining a drug used for epilepsy, bipolar disorder, and migrain ...Written By: Annie LennonJAN 02, 2020Cancer
In order to mimic the microenvironment of a tumor in the human body, researchers from Kyoto University have developed a ...Written By: Kathryn DeMuth SullivanJAN 02, 2020Drug Discovery & Development
In 2019, an estimated 46,000 Americans died from pancreatic cancer. Now, the Food and Drug Administration (FDA) has appr ...Written By: Annie LennonDEC 30, 2019Microbiology
Advances in genetic technologies made it possible for researchers to learn more about the vast community of microbes tha ...Written By: Carmen LeitchDEC 27, 2019Microbiology
It takes a long time for a drug to be approved for use in humans; repurposing existing drugs is one way to get around th ...Written By: Carmen LeitchDEC 27, 2019Drug Discovery & Development
UK regulators claim to have found a link between at least ten suicides and a powerful acne drug, manufactured under the ...Written By: Annie LennonDEC 25, 2019Drug Discovery & Development
The US Food and Drug Administration has granted accelerated approval to new breast cancer drug, trastuzumab deruxtecan. ...Written By: Annie LennonDEC 23, 2019Cell & Molecular Biology
In 2018, around ten million people around the globe were sickened by tuberculosis (TB) and about 1.5 million people were ...Written By: Carmen LeitchDEC 23, 2019Drug Discovery & Development
As announced by the Dutch Ophthalmic Research Center in a press release, a new eye solution was recently approved by the ...Written By: Nouran AminDEC 23, 2019Drug Discovery & Development
The U.S. Food and Drug Administration (FDA) has approved DAYVIGO™ (lemborexant) in 5 mg and 10 mg for the treatmen ...Written By: Nouran AminDEC 23, 2019Drug Discovery & Development
The US Food and Drug Administration (FDA) has approved an atypical antipsychotic Caplyta (lumateperone; Intra-Cellular T ...Written By: Nouran AminDEC 22, 2019Genetics & Genomics
Researchers at Ohio State University have developed a new gene therapy that makes use of exosomes, fluid sacs released i ...Written By: Annie LennonDEC 22, 2019Drug Discovery & Development
The U.S Food and Drug Administration has now approved a new medication for migraines. The drug is called ‘ubrogepa ...Written By: Nouran AminDEC 21, 2019Drug Discovery & Development
Scientists at the University of Nottingham are seeking new ways to improve vaccine use in the protection against the bac ...Written By: Nouran AminDEC 21, 2019Drug Discovery & Development
With the efficacy of selective serotonin reuptake inhibitors such as Prozac increasingly coming under question, the sear ...Written By: Annie LennonDEC 20, 2019Drug Discovery & Development
The life-threatening and treatment-resistant seizure disorder among children known as the ‘Dravet Syndrome’ ...Written By: Nouran AminDEC 20, 2019Genetics & Genomics
Down’s Syndrome (DS) is a genetic disorder brought on by the presence of all of part of a third copy of chromosome ...Written By: Annie LennonDEC 19, 2019Technology
Although artificial intelligence has many advantages in the drug discovery process, challenges still remain--one being t ...Written By: Nouran AminDEC 19, 2019Drug Discovery & Development
Every year, almost 70,000 people die from an overdose in the US. Now, a company called MindMed is testing a compound der ...Written By: Annie Lennon
JAN 13, 2020
Drug Discovery & Development
Currently Alzheimer’s disease is thought to affect around 50 million people around the world, with this figure dou
...
Written By:
Annie Lennon
JAN 12, 2020
Cell & Molecular Biology
Altering two signaling pathways extended the lives of a research model called C elegans by an astonishing 500 percent.
Written By:
Carmen Leitch
JAN 06, 2020
Drug Discovery & Development
A study published by PNAS explains breakthrough research around designing drugs that target C. diff bacterial infections
...
Written By:
Nouran Amin
JAN 04, 2020
Cardiology
Heart disease is the top killer in the Western world. This is partially because, if one manages to survive an initial he
...
Written By:
Annie Lennon
JAN 03, 2020
Drug Discovery & Development
Previously considered to be narcotic, and under tight regulation as an illicit drug for decades, research from recent ye
...
Written By:
Annie Lennon
JAN 03, 2020
Drug Discovery & Development
Researchers from Georgetown University have found that combining a drug used for epilepsy, bipolar disorder, and migrain
...
Written By:
Annie Lennon
JAN 02, 2020
Cancer
In order to mimic the microenvironment of a tumor in the human body, researchers from Kyoto University have developed a
...
Written By:
Kathryn DeMuth Sullivan
JAN 02, 2020
Drug Discovery & Development
In 2019, an estimated 46,000 Americans died from pancreatic cancer. Now, the Food and Drug Administration (FDA) has appr
...
Written By:
Annie Lennon
DEC 30, 2019
Microbiology
Advances in genetic technologies made it possible for researchers to learn more about the vast community of microbes tha
...
Written By:
Carmen Leitch
DEC 27, 2019
Microbiology
It takes a long time for a drug to be approved for use in humans; repurposing existing drugs is one way to get around th
...
Written By:
Carmen Leitch
DEC 27, 2019
Drug Discovery & Development
UK regulators claim to have found a link between at least ten suicides and a powerful acne drug, manufactured under the
...
Written By:
Annie Lennon
DEC 25, 2019
Drug Discovery & Development
The US Food and Drug Administration has granted accelerated approval to new breast cancer drug, trastuzumab deruxtecan.
...
Written By:
Annie Lennon
DEC 23, 2019
Cell & Molecular Biology
In 2018, around ten million people around the globe were sickened by tuberculosis (TB) and about 1.5 million people were
...
Written By:
Carmen Leitch
DEC 23, 2019
Drug Discovery & Development
As announced by the Dutch Ophthalmic Research Center in a press release, a new eye solution was recently approved by the
...
Written By:
Nouran Amin
DEC 23, 2019
Drug Discovery & Development
The U.S. Food and Drug Administration (FDA) has approved DAYVIGO™ (lemborexant) in 5 mg and 10 mg for the treatmen
...
Written By:
Nouran Amin
DEC 23, 2019
Drug Discovery & Development
The US Food and Drug Administration (FDA) has approved an atypical antipsychotic Caplyta (lumateperone; Intra-Cellular T
...
Written By:
Nouran Amin
DEC 22, 2019
Genetics & Genomics
Researchers at Ohio State University have developed a new gene therapy that makes use of exosomes, fluid sacs released i
...
Written By:
Annie Lennon
DEC 22, 2019
Drug Discovery & Development
The U.S Food and Drug Administration has now approved a new medication for migraines. The drug is called ‘ubrogepa
...
Written By:
Nouran Amin
DEC 21, 2019
Drug Discovery & Development
Scientists at the University of Nottingham are seeking new ways to improve vaccine use in the protection against the bac
...
Written By:
Nouran Amin
DEC 21, 2019
Drug Discovery & Development
With the efficacy of selective serotonin reuptake inhibitors such as Prozac increasingly coming under question, the sear
...
Written By:
Annie Lennon
DEC 20, 2019
Drug Discovery & Development
The life-threatening and treatment-resistant seizure disorder among children known as the ‘Dravet Syndrome’
...
Written By:
Nouran Amin
DEC 20, 2019
Genetics & Genomics
Down’s Syndrome (DS) is a genetic disorder brought on by the presence of all of part of a third copy of chromosome
...
Written By:
Annie Lennon
DEC 19, 2019
Technology
Although artificial intelligence has many advantages in the drug discovery process, challenges still remain--one being t
...
Written By:
Nouran Amin
DEC 19, 2019
Drug Discovery & Development
Every year, almost 70,000 people die from an overdose in the US. Now, a company called MindMed is testing a compound der
...
Written By:
Annie Lennon