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    Gene Editing

    Gene Editing: a type of genetic engineering in which DNA is inserted, deleted or replaced in the genome of a living organism using engineered nucleases, or "molecular scissors". These nucleases create site-specific double-strand breaks (DSBs) at desired locations in the genome. The induced double-strand breaks are repaired through nonhomologous end-joining (NHEJ) or homologous recombination (HR), resulting in targeted mutations.

    Trending News

    • DEC 01, 2022
      Genetics & Genomics
      How the CRISPR Gene Editor Can Activate Protein Scissors
      How the CRISPR Gene Editor Can Activate Protein Scissors
      The CRISPR/Cas9 gene editing tool has changed biomedical research, and has even been used in the clinic in a few cases t ...
      Written By: Carmen Leitch
      3
      NOV 30, 2022
      Immunology
      Rogue, Cancer-Linked Immune Cells Found to Drive Autoimmune Disorders
      Rogue, Cancer-Linked Immune Cells Found to Drive Autoimmune Disorders
      Leukemia patients are more likely to get autoimmune disorders like aplastic anemia or rheumatoid arthritis than unaffect ...
      Written By: Carmen Leitch
      1
      NOV 10, 2022
      Neuroscience
      HUSH - A Complex That Silences Genes & Helps Control Brain Architecture
      HUSH - A Complex That Silences Genes & Helps Control Brain Architecture
      The HUSH (human silencing hub) protein complex is known to silence genes, and researchers have thought that it could be ...
      Written By: Carmen Leitch
      1
      NOV 09, 2022
      Genetics & Genomics
      Want to Study Copy Number Alterations in Cells? Bring MACHETE
      Want to Study Copy Number Alterations in Cells? Bring MACHETE
      Sure, MACHETE is a cool name, but the researchers that developed the technique are hoping people don't focus solely on t ...
      Written By: Carmen Leitch
      1
      NOV 06, 2022
      Genetics & Genomics
      The Lone Participant in a CRISPR Therapy Trial has Died
      The Lone Participant in a CRISPR Therapy Trial has Died
      In August of this year, a single patient was enrolled in a trial that used CRISPR to correct a genetic mutation that led ...
      Written By: Carmen Leitch
      3
      OCT 27, 2022
      Genetics & Genomics
      Creating a Gene Therapy to Treat an Iron Storage Disorder
      Creating a Gene Therapy to Treat an Iron Storage Disorder
      Hereditary hemochromatosis (HH) is caused by genetic mutations that lead to the abnormal accumulation of iron in differe ...
      Written By: Carmen Leitch
      4
      OCT 25, 2022
      Cell & Molecular Biology
      Liver Disease Discovery Resolves Controversy
      Liver Disease Discovery Resolves Controversy
      Liver diseases are a serious health problem. Chronic liver disease is estimated to impact over 1.5 billion people.
      Written By: Carmen Leitch
      4
      OCT 21, 2022
      Genetics & Genomics
      Recognizing the Importance of SARS-CoV-2 'Accessory' Genes
      Recognizing the Importance of SARS-CoV-2 'Accessory' Genes
      The genome of the virus that causes COVID-19, SARS-CoV-2, is very small. But it encodes for more than just the spike pro ...
      Written By: Carmen Leitch
      3
      OCT 20, 2022
      Microbiology
      Building a Better Beer Through Microbiology
      Building a Better Beer Through Microbiology
      Belgium as long been known for its beer, and now, Belgian researchers have used genetic technology to improve the brew.
      Written By: Carmen Leitch
      2
      OCT 13, 2022
      Cancer
      Gene Editing Beyond CRISPR-Cas9: Base Editors
      Gene Editing Beyond CRISPR-Cas9: Base Editors
      Point mutations change one or very few nucleotides in DNA, but they cause an estimated 30,000 genetic diseases in humans ...
      Sponsored By: MaxCyte®
      6
      SEP 25, 2022
      Cell & Molecular Biology
      New Imaging Tools Provide Insights Into Cell Stress
      New Imaging Tools Provide Insights Into Cell Stress
      In cells, active genes are transcribed into mRNA molecules, which can be edited and processed in a variety of ways, to u ...
      Written By: Carmen Leitch
      2
      SEP 22, 2022
      Cell & Molecular Biology
      Human Protein Crucial to Infection & Disease is Discovered
      Human Protein Crucial to Infection & Disease is Discovered
      The pandemic virus SARS-CoV-2 caused many scientists to begin studying infectious disease, in search of ways to stop the ...
      Written By: Carmen Leitch
      3
      SEP 06, 2022
      Genetics & Genomics
      Reduced A-to-I Editing in RNA Linked to Autoimmune Disorder Risk
      Reduced A-to-I Editing in RNA Linked to Autoimmune Disorder Risk
      The genome contains the sequences for protein-coding genes, but before those seuquences are translated into protein, the ...
      Written By: Carmen Leitch
      2
      SEP 05, 2022
      Cell & Molecular Biology
      Making Genetic Engineering at the Chromosome Level Possible
      Making Genetic Engineering at the Chromosome Level Possible
      An image by Wang Qiang shows a mouse that carries two chromosomes fused together, the first engineered karyotype in mice ...
      Written By: Carmen Leitch
      3
      SEP 01, 2022
      Cell & Molecular Biology
      Craspase - A CRISPR System That Cuts Proteins
      Craspase - A CRISPR System That Cuts Proteins
      The CRISPR/Cas9 gene editing system has revolutionized biomedical research, and has now even been used in the clinic is ...
      Written By: Carmen Leitch
      2
      AUG 17, 2022
      Cell & Molecular Biology
      An Antiviral Defense Mechanism That's Shared Across All Domains of Life
      An Antiviral Defense Mechanism That's Shared Across All Domains of Life
      Surprisingly similar mechanisms of pattern recognition can be found among incredibly diverse organisms.
      Written By: Carmen Leitch
      2
      AUG 14, 2022
      Immunology
      After Transplant, Another Person is Cured of HIV
      After Transplant, Another Person is Cured of HIV
      For the second time this year and only the fourth time ever, researchers have announced that a person has been cured of ...
      Written By: Carmen Leitch
      3
      AUG 10, 2022
      Genetics & Genomics
      CRISPR/Cas9 Gene Editing can be Toxic to Cells & Disrupt Genome Stability
      CRISPR/Cas9 Gene Editing can be Toxic to Cells & Disrupt Genome Stability
      Errors in human genes can lead to many different types of diseases, and scientists have been searching for ways to corre ...
      Written By: Carmen Leitch
      2
      AUG 04, 2022
      Cell & Molecular Biology
      Massive Gene Transfer From Bacteria to Fly is Discovered
      Massive Gene Transfer From Bacteria to Fly is Discovered
      Researchers used new long-read genetic sequencing technology to show that there are bacterial genomes within the genome ...
      Written By: Carmen Leitch
      1
      AUG 02, 2022
      Clinical & Molecular DX
      CRISPR Technology Breaks New Ground with Edits to Gene that Regulates Cholesterol
      CRISPR Technology Breaks New Ground with Edits to Gene that Regulates Cholesterol
      In 2013, scientists described a method for editing the genome of eukaryotic cells (such at those found in humans) using ...
      Written By: Zoe Michaud
      1
      JUL 31, 2022
      Genetics & Genomics
      A Brief History of Human Gene Editing
      A Brief History of Human Gene Editing
      DNA was characterized in 1953, and shortly after, the nature of the genetic code was revealed.
      Written By: Carmen Leitch
      4
      JUL 01, 2022
      Cannabis Sciences
      Firefly Genes Provide Insights into Cannabis Biology
      Firefly Genes Provide Insights into Cannabis Biology
      A team of University of Connecticut researchers are using firefly genes to understand molecular mechanisms involved in t ...
      Written By: Kerry Charron
      1
      JUN 20, 2022
      Cell & Molecular Biology
      Rethinking What We Know About Blood Cell Formation
      Rethinking What We Know About Blood Cell Formation
      An image by Sachin H. Patel/Boston Children's Hospital shows embryonic multipotent progenitor cells in a mouse embryo's ...
      Written By: Carmen Leitch
      2
      JUN 02, 2022
      Genetics & Genomics
      'Short Term' Gene-Editing Corrects a Disease-Causing Mutation
      'Short Term' Gene-Editing Corrects a Disease-Causing Mutation
      There are about three billion bases in the human genome, and each letter is either an adenine (A), thymine (T), cytosine ...
      Written By: Carmen Leitch
      3
    DEC 01, 2022
    Genetics & Genomics
    How the CRISPR Gene Editor Can Activate Protein Scissors
    How the CRISPR Gene Editor Can Activate Protein Scissors
    The CRISPR/Cas9 gene editing tool has changed biomedical research, and has even been used in the clinic in a few cases t ...
    Written By: Carmen Leitch
    3
    NOV 30, 2022
    Immunology
    Rogue, Cancer-Linked Immune Cells Found to Drive Autoimmune Disorders
    Rogue, Cancer-Linked Immune Cells Found to Drive Autoimmune Disorders
    Leukemia patients are more likely to get autoimmune disorders like aplastic anemia or rheumatoid arthritis than unaffect ...
    Written By: Carmen Leitch
    1
    NOV 10, 2022
    Neuroscience
    HUSH - A Complex That Silences Genes & Helps Control Brain Architecture
    HUSH - A Complex That Silences Genes & Helps Control Brain Architecture
    The HUSH (human silencing hub) protein complex is known to silence genes, and researchers have thought that it could be ...
    Written By: Carmen Leitch
    1
    NOV 09, 2022
    Genetics & Genomics
    Want to Study Copy Number Alterations in Cells? Bring MACHETE
    Want to Study Copy Number Alterations in Cells? Bring MACHETE
    Sure, MACHETE is a cool name, but the researchers that developed the technique are hoping people don't focus solely on t ...
    Written By: Carmen Leitch
    1
    NOV 06, 2022
    Genetics & Genomics
    The Lone Participant in a CRISPR Therapy Trial has Died
    The Lone Participant in a CRISPR Therapy Trial has Died
    In August of this year, a single patient was enrolled in a trial that used CRISPR to correct a genetic mutation that led ...
    Written By: Carmen Leitch
    3
     
     
  • OCT 27, 2022
    Genetics & Genomics
    Creating a Gene Therapy to Treat an Iron Storage Disorder
    Creating a Gene Therapy to Treat an Iron Storage Disorder
    Hereditary hemochromatosis (HH) is caused by genetic mutations that lead to the abnormal accumulation of iron in differe ...
    Written By: Carmen Leitch
    4
    OCT 25, 2022
    Cell & Molecular Biology
    Liver Disease Discovery Resolves Controversy
    Liver Disease Discovery Resolves Controversy
    Liver diseases are a serious health problem. Chronic liver disease is estimated to impact over 1.5 billion people.
    Written By: Carmen Leitch
    4
    OCT 21, 2022
    Genetics & Genomics
    Recognizing the Importance of SARS-CoV-2 'Accessory' Genes
    Recognizing the Importance of SARS-CoV-2 'Accessory' Genes
    The genome of the virus that causes COVID-19, SARS-CoV-2, is very small. But it encodes for more than just the spike pro ...
    Written By: Carmen Leitch
    3
    OCT 20, 2022
    Microbiology
    Building a Better Beer Through Microbiology
    Building a Better Beer Through Microbiology
    Belgium as long been known for its beer, and now, Belgian researchers have used genetic technology to improve the brew.
    Written By: Carmen Leitch
    2
    OCT 13, 2022
    Cancer
    Gene Editing Beyond CRISPR-Cas9: Base Editors
    Gene Editing Beyond CRISPR-Cas9: Base Editors
    Point mutations change one or very few nucleotides in DNA, but they cause an estimated 30,000 genetic diseases in humans ...
    Sponsored By: MaxCyte®
    6
     
     
  • SEP 25, 2022
    Cell & Molecular Biology
    New Imaging Tools Provide Insights Into Cell Stress
    New Imaging Tools Provide Insights Into Cell Stress
    In cells, active genes are transcribed into mRNA molecules, which can be edited and processed in a variety of ways, to u ...
    Written By: Carmen Leitch
    2
    SEP 22, 2022
    Cell & Molecular Biology
    Human Protein Crucial to Infection & Disease is Discovered
    Human Protein Crucial to Infection & Disease is Discovered
    The pandemic virus SARS-CoV-2 caused many scientists to begin studying infectious disease, in search of ways to stop the ...
    Written By: Carmen Leitch
    3
    SEP 06, 2022
    Genetics & Genomics
    Reduced A-to-I Editing in RNA Linked to Autoimmune Disorder Risk
    Reduced A-to-I Editing in RNA Linked to Autoimmune Disorder Risk
    The genome contains the sequences for protein-coding genes, but before those seuquences are translated into protein, the ...
    Written By: Carmen Leitch
    2
    SEP 05, 2022
    Cell & Molecular Biology
    Making Genetic Engineering at the Chromosome Level Possible
    Making Genetic Engineering at the Chromosome Level Possible
    An image by Wang Qiang shows a mouse that carries two chromosomes fused together, the first engineered karyotype in mice ...
    Written By: Carmen Leitch
    3
    SEP 01, 2022
    Cell & Molecular Biology
    Craspase - A CRISPR System That Cuts Proteins
    Craspase - A CRISPR System That Cuts Proteins
    The CRISPR/Cas9 gene editing system has revolutionized biomedical research, and has now even been used in the clinic is ...
    Written By: Carmen Leitch
    2
     
     
  • AUG 17, 2022
    Cell & Molecular Biology
    An Antiviral Defense Mechanism That's Shared Across All Domains of Life
    An Antiviral Defense Mechanism That's Shared Across All Domains of Life
    Surprisingly similar mechanisms of pattern recognition can be found among incredibly diverse organisms.
    Written By: Carmen Leitch
    2
    AUG 14, 2022
    Immunology
    After Transplant, Another Person is Cured of HIV
    After Transplant, Another Person is Cured of HIV
    For the second time this year and only the fourth time ever, researchers have announced that a person has been cured of ...
    Written By: Carmen Leitch
    3
    AUG 10, 2022
    Genetics & Genomics
    CRISPR/Cas9 Gene Editing can be Toxic to Cells & Disrupt Genome Stability
    CRISPR/Cas9 Gene Editing can be Toxic to Cells & Disrupt Genome Stability
    Errors in human genes can lead to many different types of diseases, and scientists have been searching for ways to corre ...
    Written By: Carmen Leitch
    2
    AUG 04, 2022
    Cell & Molecular Biology
    Massive Gene Transfer From Bacteria to Fly is Discovered
    Massive Gene Transfer From Bacteria to Fly is Discovered
    Researchers used new long-read genetic sequencing technology to show that there are bacterial genomes within the genome ...
    Written By: Carmen Leitch
    1
    AUG 02, 2022
    Clinical & Molecular DX
    CRISPR Technology Breaks New Ground with Edits to Gene that Regulates Cholesterol
    CRISPR Technology Breaks New Ground with Edits to Gene that Regulates Cholesterol
    In 2013, scientists described a method for editing the genome of eukaryotic cells (such at those found in humans) using ...
    Written By: Zoe Michaud
    1
     
     
  • JUL 31, 2022
    Genetics & Genomics
    A Brief History of Human Gene Editing
    A Brief History of Human Gene Editing
    DNA was characterized in 1953, and shortly after, the nature of the genetic code was revealed.
    Written By: Carmen Leitch
    4
    JUL 01, 2022
    Cannabis Sciences
    Firefly Genes Provide Insights into Cannabis Biology
    Firefly Genes Provide Insights into Cannabis Biology
    A team of University of Connecticut researchers are using firefly genes to understand molecular mechanisms involved in t ...
    Written By: Kerry Charron
    1
    JUN 20, 2022
    Cell & Molecular Biology
    Rethinking What We Know About Blood Cell Formation
    Rethinking What We Know About Blood Cell Formation
    An image by Sachin H. Patel/Boston Children's Hospital shows embryonic multipotent progenitor cells in a mouse embryo's ...
    Written By: Carmen Leitch
    2
    JUN 02, 2022
    Genetics & Genomics
    'Short Term' Gene-Editing Corrects a Disease-Causing Mutation
    'Short Term' Gene-Editing Corrects a Disease-Causing Mutation
    There are about three billion bases in the human genome, and each letter is either an adenine (A), thymine (T), cytosine ...
    Written By: Carmen Leitch
    3
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