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    Gene Editing

    Gene Editing: a type of genetic engineering in which DNA is inserted, deleted or replaced in the genome of a living organism using engineered nucleases, or "molecular scissors". These nucleases create site-specific double-strand breaks (DSBs) at desired locations in the genome. The induced double-strand breaks are repaired through nonhomologous end-joining (NHEJ) or homologous recombination (HR), resulting in targeted mutations.

    Trending News

    • JUN 26, 2023
      Genetics & Genomics
      First Gene Therapy to Treat Duchenne Muscular Dystrophy is Approved
      First Gene Therapy to Treat Duchenne Muscular Dystrophy is Approved
      The first gene therapy that can treat Duchenne muscular dystrophy (DMD) has been approved by the U.S. Food and Drug Admi ...
      Written By: Carmen Leitch
      4
      JUN 07, 2023
      Microbiology
      After a Death in a Clinical Trial, Researchers Determine the Likely Cause
      After a Death in a Clinical Trial, Researchers Determine the Likely Cause
      Last year, one person completed a trial of a CRISPR-based treatment for a rare type of Duchenne muscular dystrophy, but ...
      Written By: Carmen Leitch
      6
      MAY 22, 2023
      Cell & Molecular Biology
      A Treatment Approach for Fragile X Syndrome
      A Treatment Approach for Fragile X Syndrome
      Fragile X syndrome is the most commonly inherited form of developmental and intellectual disability. Now scientists may ...
      Written By: Carmen Leitch
      3
      APR 16, 2023
      Cell & Molecular Biology
      Revealing the Impact of Drastic RNA Editing Changes in Schizophrenia
      Revealing the Impact of Drastic RNA Editing Changes in Schizophrenia
      This work has also highlighted the importance of assessing a diverse group of patients when studying a disease.
      Written By: Carmen Leitch
      3
      APR 16, 2023
      Genetics & Genomics
      Gene Transcription Gets Faster but Gains Flaws with Age
      Gene Transcription Gets Faster but Gains Flaws with Age
      Scientists have shown how interventions like a reduced calorie diet can promote healthier aging processes.
      Written By: Carmen Leitch
      4
      APR 07, 2023
      Technology
      New Cell-Sized Micro-Robot Can Identify and Capture Other Cells
      New Cell-Sized Micro-Robot Can Identify and Capture Other Cells
      How small can robots get, and can they assist in human body needs? This is what a team of researchers led by the Univers ...
      Written By: Laurence Tognetti, MSc
      2
      APR 02, 2023
      Genetics & Genomics
      Advances in Spinal Muscular Atrophy Present Potential Treatment Options
      Advances in Spinal Muscular Atrophy Present Potential Treatment Options
      SMA is a leading cause of infant mortality. Most cases of the disease are caused by mutations in a gene called SMN1 that ...
      Written By: Carmen Leitch
      2
      APR 02, 2023
      Microbiology
      A Bacterial Injection System Can Deliver Proteins to Cells
      A Bacterial Injection System Can Deliver Proteins to Cells
      Nature has designed some spectacular micromachines, such as the flagella that propel bacterial cells, or microbial injec ...
      Written By: Carmen Leitch
      3
      MAR 22, 2023
      Genetics & Genomics
      Advanced Gene Editing Method Restores Vision in Mouse Model
      Advanced Gene Editing Method Restores Vision in Mouse Model
      CRISPR is a gene editing technique with incredible potential. But the traditional CRISPR-Cas9 approach involves cutting ...
      Written By: Carmen Leitch
      3
      MAR 19, 2023
      Genetics & Genomics
      Researchers Create Mice From Two Fathers
      Researchers Create Mice From Two Fathers
      A proof-of-concept experiment in which a mouse was produced from two biological fathers has been announced at this year' ...
      Written By: Carmen Leitch
      6
      MAR 15, 2023
      Genetics & Genomics
      Experts Conclude Genome Editing in Human Embryos Still Too Risky
      Experts Conclude Genome Editing in Human Embryos Still Too Risky
      The Third International Summit on Human Genome Editing has concluded, and experts have agreed that human genome editing ...
      Written By: Carmen Leitch
      4
      MAR 08, 2023
      Genetics & Genomics
      How Researchers Engineered a Mouse Model of Bipolar Disorder
      How Researchers Engineered a Mouse Model of Bipolar Disorder
      People with bipolar disorder (BD) have alternating episodes of depression and mania, in which they are abnormally irrita ...
      Written By: Carmen Leitch
      3
      MAR 08, 2023
      Cancer
      Why Automation is Outpacing Traditional Methods for Single-Cell Cloning
      Why Automation is Outpacing Traditional Methods for Single-Cell Cloning
      Genetic modification of mammalian cells has vast use in biotherapeutics development and basic research applications. An ...
      Sponsored By: Sartorius
      3
      FEB 27, 2023
      Genetics & Genomics
      Building More Resilient Wheat
      Building More Resilient Wheat
      The climate is changing and making droughts more severe and frequent. That is expected to impact food production too, as ...
      Written By: Carmen Leitch
      1
      FEB 24, 2023
      Genetics & Genomics
      The 'Sixth Sense' May be Far More Common Than we Knew
      The 'Sixth Sense' May be Far More Common Than we Knew
      The earth has a magnetic field, and some animals such as monarch butterflies and turtles can use it to navigate during l ...
      Written By: Carmen Leitch
      3
      FEB 08, 2023
      Cell & Molecular Biology
      Intermittent Fasting Triggers Liver Cell Growth in Mice
      Intermittent Fasting Triggers Liver Cell Growth in Mice
      An intermittent fasting https://www.hopkinsmedicine.org/health/wellness-and-prevention/intermittent-fasting-what-is-it-a ...
      Written By: Carmen Leitch
      1
      FEB 05, 2023
      Cell & Molecular Biology
      How the Loss of a Protein May Improve Stroke Recovery
      How the Loss of a Protein May Improve Stroke Recovery
      Astrocytes are named for their star shape, and these cells, once thought to be supporting players, are now being appreci ...
      Written By: Carmen Leitch
      1
      FEB 03, 2023
      Chemistry & Physics
      The (Unimportant?) Role of Love Hormones in Prairie Voles
      The (Unimportant?) Role of Love Hormones in Prairie Voles
      New research finds that oxytocin may not be as important in prairie voles as it is in other mammals.
      Written By: Brittany Kenyon-Flatt
      1
      JAN 25, 2023
      Technology
      Researchers Use Mice to Experiment with Silica Nano-Sized Capsules Carrying Gene-Editing Tools
      Researchers Use Mice to Experiment with Silica Nano-Sized Capsules Carrying Gene-Editing Tools
      In a recent study published in Advanced Materials, a team of researchers at the University of Wisconsin-Madison have dev ...
      Written By: Laurence Tognetti, MSc
      1
      JAN 08, 2023
      Genetics & Genomics
      Challenges and Successes in Human CRISPR Trials
      Challenges and Successes in Human CRISPR Trials
      A human trial of a CRISPR therapy was recently halted for adverse events. But the technology has tremendous potential to ...
      Written By: Carmen Leitch
      2
      JAN 05, 2023
      Cell & Molecular Biology
      CRISPR-Cas12a2 - A New Kind of Gene Scissors
      CRISPR-Cas12a2 - A New Kind of Gene Scissors
      Microbes have long been engaged in an arms race for dominance, and they have molecular weapons, and defense mechanisms. ...
      Written By: Carmen Leitch
      1
      JAN 01, 2023
      Genetics & Genomics
      How Gene Editing Could Spare Billions of Chicks Every Year
      How Gene Editing Could Spare Billions of Chicks Every Year
      In December 2022, researchers reported that they'd developed a technique in which single-sex litters could be created. T ...
      Written By: Carmen Leitch
      2
      DEC 27, 2022
      Genetics & Genomics
      Correcting Genetic Mutations Leading to Heart Disease with CRISPR
      Correcting Genetic Mutations Leading to Heart Disease with CRISPR
      The researchers are hopeful that people in the clinic can be treated with this method within a few years.
      Written By: Carmen Leitch
      1
      DEC 23, 2022
      Genetics & Genomics
      Gene Therapy Successfully Treats Artemis-SCID Patients
      Gene Therapy Successfully Treats Artemis-SCID Patients
      Mutations in a handful of genes can cause severe combined immunodeficiency (SCID), which severely disrupts the body's ab ...
      Written By: Carmen Leitch
      2
    JUN 26, 2023
    Genetics & Genomics
    First Gene Therapy to Treat Duchenne Muscular Dystrophy is Approved
    First Gene Therapy to Treat Duchenne Muscular Dystrophy is Approved
    The first gene therapy that can treat Duchenne muscular dystrophy (DMD) has been approved by the U.S. Food and Drug Admi ...
    Written By: Carmen Leitch
    4
    JUN 07, 2023
    Microbiology
    After a Death in a Clinical Trial, Researchers Determine the Likely Cause
    After a Death in a Clinical Trial, Researchers Determine the Likely Cause
    Last year, one person completed a trial of a CRISPR-based treatment for a rare type of Duchenne muscular dystrophy, but ...
    Written By: Carmen Leitch
    6
    MAY 22, 2023
    Cell & Molecular Biology
    A Treatment Approach for Fragile X Syndrome
    A Treatment Approach for Fragile X Syndrome
    Fragile X syndrome is the most commonly inherited form of developmental and intellectual disability. Now scientists may ...
    Written By: Carmen Leitch
    3
    APR 16, 2023
    Cell & Molecular Biology
    Revealing the Impact of Drastic RNA Editing Changes in Schizophrenia
    Revealing the Impact of Drastic RNA Editing Changes in Schizophrenia
    This work has also highlighted the importance of assessing a diverse group of patients when studying a disease.
    Written By: Carmen Leitch
    3
    APR 16, 2023
    Genetics & Genomics
    Gene Transcription Gets Faster but Gains Flaws with Age
    Gene Transcription Gets Faster but Gains Flaws with Age
    Scientists have shown how interventions like a reduced calorie diet can promote healthier aging processes.
    Written By: Carmen Leitch
    4
     
     
  • APR 07, 2023
    Technology
    New Cell-Sized Micro-Robot Can Identify and Capture Other Cells
    New Cell-Sized Micro-Robot Can Identify and Capture Other Cells
    How small can robots get, and can they assist in human body needs? This is what a team of researchers led by the Univers ...
    Written By: Laurence Tognetti, MSc
    2
    APR 02, 2023
    Genetics & Genomics
    Advances in Spinal Muscular Atrophy Present Potential Treatment Options
    Advances in Spinal Muscular Atrophy Present Potential Treatment Options
    SMA is a leading cause of infant mortality. Most cases of the disease are caused by mutations in a gene called SMN1 that ...
    Written By: Carmen Leitch
    2
    APR 02, 2023
    Microbiology
    A Bacterial Injection System Can Deliver Proteins to Cells
    A Bacterial Injection System Can Deliver Proteins to Cells
    Nature has designed some spectacular micromachines, such as the flagella that propel bacterial cells, or microbial injec ...
    Written By: Carmen Leitch
    3
    MAR 22, 2023
    Genetics & Genomics
    Advanced Gene Editing Method Restores Vision in Mouse Model
    Advanced Gene Editing Method Restores Vision in Mouse Model
    CRISPR is a gene editing technique with incredible potential. But the traditional CRISPR-Cas9 approach involves cutting ...
    Written By: Carmen Leitch
    3
    MAR 19, 2023
    Genetics & Genomics
    Researchers Create Mice From Two Fathers
    Researchers Create Mice From Two Fathers
    A proof-of-concept experiment in which a mouse was produced from two biological fathers has been announced at this year' ...
    Written By: Carmen Leitch
    6
     
     
  • MAR 15, 2023
    Genetics & Genomics
    Experts Conclude Genome Editing in Human Embryos Still Too Risky
    Experts Conclude Genome Editing in Human Embryos Still Too Risky
    The Third International Summit on Human Genome Editing has concluded, and experts have agreed that human genome editing ...
    Written By: Carmen Leitch
    4
    MAR 08, 2023
    Genetics & Genomics
    How Researchers Engineered a Mouse Model of Bipolar Disorder
    How Researchers Engineered a Mouse Model of Bipolar Disorder
    People with bipolar disorder (BD) have alternating episodes of depression and mania, in which they are abnormally irrita ...
    Written By: Carmen Leitch
    3
    MAR 08, 2023
    Cancer
    Why Automation is Outpacing Traditional Methods for Single-Cell Cloning
    Why Automation is Outpacing Traditional Methods for Single-Cell Cloning
    Genetic modification of mammalian cells has vast use in biotherapeutics development and basic research applications. An ...
    Sponsored By: Sartorius
    3
    FEB 27, 2023
    Genetics & Genomics
    Building More Resilient Wheat
    Building More Resilient Wheat
    The climate is changing and making droughts more severe and frequent. That is expected to impact food production too, as ...
    Written By: Carmen Leitch
    1
    FEB 24, 2023
    Genetics & Genomics
    The 'Sixth Sense' May be Far More Common Than we Knew
    The 'Sixth Sense' May be Far More Common Than we Knew
    The earth has a magnetic field, and some animals such as monarch butterflies and turtles can use it to navigate during l ...
    Written By: Carmen Leitch
    3
     
     
  • FEB 08, 2023
    Cell & Molecular Biology
    Intermittent Fasting Triggers Liver Cell Growth in Mice
    Intermittent Fasting Triggers Liver Cell Growth in Mice
    An intermittent fasting https://www.hopkinsmedicine.org/health/wellness-and-prevention/intermittent-fasting-what-is-it-a ...
    Written By: Carmen Leitch
    1
    FEB 05, 2023
    Cell & Molecular Biology
    How the Loss of a Protein May Improve Stroke Recovery
    How the Loss of a Protein May Improve Stroke Recovery
    Astrocytes are named for their star shape, and these cells, once thought to be supporting players, are now being appreci ...
    Written By: Carmen Leitch
    1
    FEB 03, 2023
    Chemistry & Physics
    The (Unimportant?) Role of Love Hormones in Prairie Voles
    The (Unimportant?) Role of Love Hormones in Prairie Voles
    New research finds that oxytocin may not be as important in prairie voles as it is in other mammals.
    Written By: Brittany Kenyon-Flatt
    1
    JAN 25, 2023
    Technology
    Researchers Use Mice to Experiment with Silica Nano-Sized Capsules Carrying Gene-Editing Tools
    Researchers Use Mice to Experiment with Silica Nano-Sized Capsules Carrying Gene-Editing Tools
    In a recent study published in Advanced Materials, a team of researchers at the University of Wisconsin-Madison have dev ...
    Written By: Laurence Tognetti, MSc
    1
    JAN 08, 2023
    Genetics & Genomics
    Challenges and Successes in Human CRISPR Trials
    Challenges and Successes in Human CRISPR Trials
    A human trial of a CRISPR therapy was recently halted for adverse events. But the technology has tremendous potential to ...
    Written By: Carmen Leitch
    2
     
     
  • JAN 05, 2023
    Cell & Molecular Biology
    CRISPR-Cas12a2 - A New Kind of Gene Scissors
    CRISPR-Cas12a2 - A New Kind of Gene Scissors
    Microbes have long been engaged in an arms race for dominance, and they have molecular weapons, and defense mechanisms. ...
    Written By: Carmen Leitch
    1
    JAN 01, 2023
    Genetics & Genomics
    How Gene Editing Could Spare Billions of Chicks Every Year
    How Gene Editing Could Spare Billions of Chicks Every Year
    In December 2022, researchers reported that they'd developed a technique in which single-sex litters could be created. T ...
    Written By: Carmen Leitch
    2
    DEC 27, 2022
    Genetics & Genomics
    Correcting Genetic Mutations Leading to Heart Disease with CRISPR
    Correcting Genetic Mutations Leading to Heart Disease with CRISPR
    The researchers are hopeful that people in the clinic can be treated with this method within a few years.
    Written By: Carmen Leitch
    1
    DEC 23, 2022
    Genetics & Genomics
    Gene Therapy Successfully Treats Artemis-SCID Patients
    Gene Therapy Successfully Treats Artemis-SCID Patients
    Mutations in a handful of genes can cause severe combined immunodeficiency (SCID), which severely disrupts the body's ab ...
    Written By: Carmen Leitch
    2
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