Gene Therapy: Gene therapy is designed to introduce genetic material into cells to compensate for abnormal genes or to make a beneficial protein. If a mutated gene causes a necessary protein to be faulty or missing, gene therapy may be able to introduce a normal copy of the gene to restore the function of the protein.
The downstream processing of virus particles, vesicles, RNAs, plasmids and other forms of DNA, contains multiple interdependent steps, each requiring optimization for best results. This webi...
Determining the purity of LNPs loaded with nucleic acids can be challenging due to their size heterogeneity. Here, we present analytical ultracentrifugation (AUC) methods that use multiwavel...
CGX10 Cell Isolation System: Introduction, Utility, and Assessment in a GMP-grade Environment for Multiparametric Cell Sorting A future of long-term, minimally toxic immunotherapy personaliz...
Tumor genomic profiling can be complicated, especially for diseases that commonly have multiple different genomic biomarkers of interest, such as non-small cell lung cancer (NSCLC) and color...
AAVs and LNPs are complementary gene transfer systems with respect to immunogenicity, tissue tropism and types of nucleic acids, which can be delivered. AUC provides a wealth of orthogonal a...
To bring your cutting-edge cell and gene therapies to the patients that need them as quickly as possible, you need access to the most knowledgeable scientists, innovative technologies, metho...
In the past decade, gene editing has been increasingly emphasized as an essential tool for therapy development. This has led to significant scientific advances in understanding disease mecha...
Gene therapy holds potential for treating neurological diseases by delivering genetic information into specific cell types. However, selective and efficient targeting of cell types remains c...
This webinar is hosted by Thermo Fisher Scientific in collaboration with the Walter and Eliza Hall Institute of Medical Research (WEHI). The webinar aims to demonstrate the benefits of the E...
To bring your cutting-edge cell and gene therapies to the patients that need them as quickly as possible, you need access to the most knowledgeable scientists, innovative technologies, metho...
For patients with advanced non-small cell lung cancer (NSCLC), tissue samples are typically small biopsies. These samples undergo standard of care evaluation for >10 biomarkers to identif...
In the world of advanced medical research, the convergence of synthetic biology and cellular immunotherapy has inaugurated a new era in field of cancer treatment. Simultaneously, life scienc...