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    Genetic Disease

    Genetic diseases are disorders stemming from mutations in an individual's DNA sequence. These conditions can be a result of mutations in a single or multiple genes. An example of a genetic disease is cystic fibrosis: an inherited, progressive disease that affects the respiratory system.

    Webinars

    • SEP 17, 2020 | 2:00 PM
      Keynote Presentation: The formation of an International Collaborative Network to find COVID-19 Therapeutics
      Keynote Presentation: The formation of an International Collaborative...
      Learning Objectives: 1. Understanding the integral value of collaboration for advancement in scientific research; how to establish and grow academic, Pharma, and industry connections 2. Lear...
      Speaker: Jacqueline Fabius , Nevan Krogan, PhD
      Presented at: Coronavirus Series
      1
      SEP 17, 2020 | 1:00 PM
      Keynote Presentation: SARS-CoV-2 Susceptibility, Transmission and Reinfection in Domestic Cats
      Keynote Presentation: SARS-CoV-2 Susceptibility, Transmission...
      Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the cause of Coronavirus Disease 2019 (COVID-19) and responsible for the current pandemic. Here, we present an in-depth study...
      Speaker: Jürgen A. Richt, DVM, PhD
      Presented at: Coronavirus Series
      1
      SEP 17, 2020 | 11:00 AM
      Host and Viral Transcriptomes During COVID-19 Infection
      Host and Viral Transcriptomes During COVID-19 Infection
      In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has killed hundreds of thousands of people, including >23,000 in New York City (NYC) alone. The...
      Speaker: Christopher E. Mason, PhD
      Presented at: Coronavirus Series
      3
      SEP 17, 2020 | 9:00 AM
      Preclinical Optical Imaging of Infectious Diseases
      Preclinical Optical Imaging of Infectious Diseases
      PerkinElmer is a global leader in the development of instrumentation and probes for small animal non-invasive imaging, including optical and µCT imaging. Through optical imaging, we ha...
      Speaker: Kevin Francis, PhD
      Presented at: Coronavirus Series
      Sponsored By: PerkinElmer
      1
      SEP 17, 2020 | 9:00 AM
      Purification of cells from SARS-CoV-2 convalescent samples and potentially infectious materials with fluorescent-activated cell sorting
      Purification of cells from SARS-CoV-2 convalescent samples and...
      In recent months, we have seen a large part of the global scientific community shift to infectious disease research. In response, researchers are exploring safer and easier methods to handle...
      Speaker: Joe Ostrand, Ph.D.
      Presented at: Coronavirus Series
      Sponsored By: Miltenyi Biotec
      1
      SEP 17, 2020 | 12:00 AM
      The detection, characterization, and surveillance of the SARS-CoV-2 viral genome using hybridization capture-based NGS assay
      The detection, characterization, and surveillance of the SARS-CoV-2...
      As the spread of infectious diseases, current pandemic, and growing antimicrobial resistance (AMR) continues globally, next-generation sequencing (NGS) became a tool to diagnose infectious d...
      Speaker: Dorottya Nagy-Szakal, MD PhD
      Presented at: Coronavirus Series
      1
      SEP 16, 2020 | 6:00 AM
      A pandemic challenge - Implementing a COVID-19 Antibody test in record time!
      A pandemic challenge - Implementing a COVID-19 Antibody test in...
      Date: September 16, 2020 Time: 7:00am (PDT), 10:00am (EDT) During the early stages of the COVID-19 outbreak in the UK, there was a great deal of uncertainty. Pathology and diagnostic service...
      Speaker: Philip Craddock-Jones , Cecilia Scarponi
      Sponsored By: Ortho Clinical Diagnostics
      13 4
      SEP 10, 2020 | 1:00 PM
      Keynote Presentation: Evolution of host-specific virulence in an RNA virus of Pacific salmonid fish
      Keynote Presentation: Evolution of host-specific virulence in...
      In Pacific Northwest watersheds several species of Pacific salmonid fishes are hosts for the rhabdovirus infectious hematopoietic necrosis virus (IHNV). In this multi-host ecosystem speciali...
      Speaker: Gael Kurath, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 12:00 PM
      Bacterial strain typing and genomics characterization of multi-drug resistance with QIAGEN CLC Genomics Workbench
      Bacterial strain typing and genomics characterization of multi-drug...
      In this webinar, we will present QIAGEN CLC Genomics Workbench and its utility for bacterial isolate identification, strain discrimination using core genome multi-locus typing (cgMLST) and d...
      Speaker: Jonathan Jacobs, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      2
      SEP 10, 2020 | 10:00 AM
      Keynote Presentation: Squeezing out understanding from sequences: Genome to Phenome Connections in Viruses of Microbes
      Keynote Presentation: Squeezing out understanding from sequences:...
      Enigmatic and often vilified, viruses are now known to play important and possibly indispensable roles in the biology and ecology of cellular organisms. Evidence of viral impacts are everywh...
      Speaker: K. Eric Wommack
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 12:00 AM
      Host responses to SARS-CoV-2
      Host responses to SARS-CoV-2
      The host response to infection is a critical determinant of virus pathogenicity. Emerging viruses require the host cellular machinery to replicate and successfully infect new hosts, and must...
      Speaker: Angela L. Rasmussen, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      2
      SEP 10, 2020 | 12:00 AM
      A novel strategy to investigate longitudinal changes within the gut microbiome: Insights from mouse models of sepsis and Alzheimer's disease
      A novel strategy to investigate longitudinal changes within the...
      Sepsis is a life-threatening condition that is caused by the immune system’s inability to respond appropriately to an infection. How sepsis can change the gut microbiome in ways that a...
      Speaker: Candice M. Brown, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 12:00 AM
      Insights into Aquatic Biofilm Dynamics by High-Throughput Identification of Bacterial Isolates and Full-Length 16S rRNA Gene Surveys
      Insights into Aquatic Biofilm Dynamics by High-Throughput Identification...
      Microbial biofilms form on all aquatic surfaces and can harbor pathogenic bacteria. In the aquaculture industry, Flavobacteria species can cause serious diseases and lead to high mortality....
      Speaker: Joerg Graf, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 10, 2020 | 12:00 AM
      Challenges in tracking horizontal gene transfer of antimicrobial resistance
      Challenges in tracking horizontal gene transfer of antimicrobial...
      Focusing on the urgent clinical problem of increasing carbapenem resistance in Enterobacteriaceae we have been evaluating detection methods in clinical microbiology and molecular transmissio...
      Speaker: Amy Mathers, MD, D(ABMM)
      Presented at: Microbiology Week Virtual Event Series 2020
      4
      SEP 09, 2020 | 9:00 AM
      Keynote Presentation: Human Monoclonal Antibodies for Emerging Agents
      Keynote Presentation: Human Monoclonal Antibodies for Emerging...
      Epidemics are occurring at an increasing pace and scale. Our laboratory group has developed platform technologies for discovery of broad and potent neutralizing antibodies for many emerging...
      Speaker: James Crowe, MD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 09, 2020 | 7:30 AM
      Using cryo-EM for designing next-gen therapeutics against HIV
      Using cryo-EM for designing next-gen therapeutics against HIV
      HIV currently infects almost 40 million people worldwide. The virus is responsible for ~2 million new infections per year and ~1 million deaths. Like all retroviruses, HIV integrates a viral...
      Speaker: Dmitry Lyumkis, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: Thermo Fisher Scientific
      1
      SEP 09, 2020 | 6:00 AM
      Keynote Presentation: Causes and consequences of immune gene diversity in plants
      Keynote Presentation: Causes and consequences of immune gene diversity...
      My group is addressing fundamental questions in evolutionary biology, using both genome- and phenotype-first approaches. A few years ago, we discovered that Arabidopsis thaliana is a great m...
      Speaker: Detlef Weigel, Executive Director
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 09, 2020 | 12:00 AM
      Leveraging SMRT sequencing to resolve complex immune loci
      Leveraging SMRT sequencing to resolve complex immune loci
      The regions of our genome responsible for encoding the genes that regulate our immune response are some of the most complex and polymorphic known. This complexity encompasses multiple types...
      Speaker: Melissa L. Smith, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 09, 2020 | 12:00 AM
      A New KIR Haplotype MSA Empowers Two New Interpretation Algorithms
      A New KIR Haplotype MSA Empowers Two New Interpretation Algorithms
      Human chromosome 19q13.4 contains genes encoding killer-cell immunoglobulin-like receptors (KIR). The region has certain properties such as single nucleotide variation, structural variation,...
      Speaker: David Roe
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 09, 2020 | 12:00 AM
      Environmental stress shapes the evolution of a plant viruses towards a mutualistic relationship with its host
      Environmental stress shapes the evolution of a plant viruses towards...
      Traditionally, virology has been focused in studying the pathogenic effect of viruses. In the recent years, however, this perception is changing and viruses are being studied as mutualistic...
      Speaker: Santiago F. Elena
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 09, 2020 | 12:00 AM
      How Plant Virology Informs Emergence of Zoonotic Viruses Such as SARS-COV-2
      How Plant Virology Informs Emergence of Zoonotic Viruses Such...
      The statement by Dimitri Ivanovsky in 1882 that "the sap of leaves infected with tobacco mosaic disease retains its infectious properties even after filtration through Chamberland filte...
      Speaker: Michael Goodin, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      3
      SEP 08, 2020 | 11:00 PM
      Deep Learning by Analogy: Applying Text and Image Processing Techniques to Sequence Analysis
      Deep Learning by Analogy: Applying Text and Image Processing Techniques...
      Over the past five years there has been an explosion of research the deep learning field. Companies like Google, Facebook, and OpenAI have created neural networks that are significantly more...
      Speaker: Will Dampier, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 11:00 PM
      Applications of Machine Learning to Predict Clinical Provenance of Haemophilus influenzae
      Applications of Machine Learning to Predict Clinical Provenance...
      Background: Haemophilus influenzae is the causative agent of multiple human disease conditions among multiple sites in the human body. Underlying genetic mechanisms are elusive, particularly...
      Speaker: Joshua Earl, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 11:00 PM
      Recombination, lineage-specific mutations and the emergence of SARS-CoV-2
      Recombination, lineage-specific mutations and the emergence of...
      The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
      Speaker: Ioan Filip, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
    SEP 17, 2020 | 2:00 PM
    Keynote Presentation: The formation of an International Collaborative Network to find COVID-19 Therapeutics
    Keynote Presentation: The formation of an International Collaborative...
    Learning Objectives: 1. Understanding the integral value of collaboration for advancement in scientific research; how to establish and grow academic, Pharma, and industry connections 2. Lear...
    Speaker: Jacqueline Fabius , Nevan Krogan, PhD
    Presented at: Coronavirus Series
    1
    SEP 17, 2020 | 1:00 PM
    Keynote Presentation: SARS-CoV-2 Susceptibility, Transmission and Reinfection in Domestic Cats
    Keynote Presentation: SARS-CoV-2 Susceptibility, Transmission...
    Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the cause of Coronavirus Disease 2019 (COVID-19) and responsible for the current pandemic. Here, we present an in-depth study...
    Speaker: Jürgen A. Richt, DVM, PhD
    Presented at: Coronavirus Series
    1
    SEP 17, 2020 | 11:00 AM
    Host and Viral Transcriptomes During COVID-19 Infection
    Host and Viral Transcriptomes During COVID-19 Infection
    In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has killed hundreds of thousands of people, including >23,000 in New York City (NYC) alone. The...
    Speaker: Christopher E. Mason, PhD
    Presented at: Coronavirus Series
    3
    SEP 17, 2020 | 9:00 AM
    Preclinical Optical Imaging of Infectious Diseases
    Preclinical Optical Imaging of Infectious Diseases
    PerkinElmer is a global leader in the development of instrumentation and probes for small animal non-invasive imaging, including optical and µCT imaging. Through optical imaging, we ha...
    Speaker: Kevin Francis, PhD
    Presented at: Coronavirus Series
    Sponsored By: PerkinElmer
    1
    SEP 17, 2020 | 9:00 AM
    Purification of cells from SARS-CoV-2 convalescent samples and potentially infectious materials with fluorescent-activated cell sorting
    Purification of cells from SARS-CoV-2 convalescent samples and...
    In recent months, we have seen a large part of the global scientific community shift to infectious disease research. In response, researchers are exploring safer and easier methods to handle...
    Speaker: Joe Ostrand, Ph.D.
    Presented at: Coronavirus Series
    Sponsored By: Miltenyi Biotec
    1
     
     
  • SEP 17, 2020 | 12:00 AM
    The detection, characterization, and surveillance of the SARS-CoV-2 viral genome using hybridization capture-based NGS assay
    The detection, characterization, and surveillance of the SARS-CoV-2...
    As the spread of infectious diseases, current pandemic, and growing antimicrobial resistance (AMR) continues globally, next-generation sequencing (NGS) became a tool to diagnose infectious d...
    Speaker: Dorottya Nagy-Szakal, MD PhD
    Presented at: Coronavirus Series
    1
    SEP 16, 2020 | 6:00 AM
    A pandemic challenge - Implementing a COVID-19 Antibody test in record time!
    A pandemic challenge - Implementing a COVID-19 Antibody test in...
    Date: September 16, 2020 Time: 7:00am (PDT), 10:00am (EDT) During the early stages of the COVID-19 outbreak in the UK, there was a great deal of uncertainty. Pathology and diagnostic service...
    Speaker: Philip Craddock-Jones , Cecilia Scarponi
    Sponsored By: Ortho Clinical Diagnostics
    13 4
    SEP 10, 2020 | 1:00 PM
    Keynote Presentation: Evolution of host-specific virulence in an RNA virus of Pacific salmonid fish
    Keynote Presentation: Evolution of host-specific virulence in...
    In Pacific Northwest watersheds several species of Pacific salmonid fishes are hosts for the rhabdovirus infectious hematopoietic necrosis virus (IHNV). In this multi-host ecosystem speciali...
    Speaker: Gael Kurath, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 10, 2020 | 12:00 PM
    Bacterial strain typing and genomics characterization of multi-drug resistance with QIAGEN CLC Genomics Workbench
    Bacterial strain typing and genomics characterization of multi-drug...
    In this webinar, we will present QIAGEN CLC Genomics Workbench and its utility for bacterial isolate identification, strain discrimination using core genome multi-locus typing (cgMLST) and d...
    Speaker: Jonathan Jacobs, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    2
    SEP 10, 2020 | 10:00 AM
    Keynote Presentation: Squeezing out understanding from sequences: Genome to Phenome Connections in Viruses of Microbes
    Keynote Presentation: Squeezing out understanding from sequences:...
    Enigmatic and often vilified, viruses are now known to play important and possibly indispensable roles in the biology and ecology of cellular organisms. Evidence of viral impacts are everywh...
    Speaker: K. Eric Wommack
    Presented at: Microbiology Week Virtual Event Series 2020
    1
     
     
  • SEP 10, 2020 | 12:00 AM
    Host responses to SARS-CoV-2
    Host responses to SARS-CoV-2
    The host response to infection is a critical determinant of virus pathogenicity. Emerging viruses require the host cellular machinery to replicate and successfully infect new hosts, and must...
    Speaker: Angela L. Rasmussen, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    2
    SEP 10, 2020 | 12:00 AM
    A novel strategy to investigate longitudinal changes within the gut microbiome: Insights from mouse models of sepsis and Alzheimer's disease
    A novel strategy to investigate longitudinal changes within the...
    Sepsis is a life-threatening condition that is caused by the immune system’s inability to respond appropriately to an infection. How sepsis can change the gut microbiome in ways that a...
    Speaker: Candice M. Brown, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 10, 2020 | 12:00 AM
    Insights into Aquatic Biofilm Dynamics by High-Throughput Identification of Bacterial Isolates and Full-Length 16S rRNA Gene Surveys
    Insights into Aquatic Biofilm Dynamics by High-Throughput Identification...
    Microbial biofilms form on all aquatic surfaces and can harbor pathogenic bacteria. In the aquaculture industry, Flavobacteria species can cause serious diseases and lead to high mortality....
    Speaker: Joerg Graf, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 10, 2020 | 12:00 AM
    Challenges in tracking horizontal gene transfer of antimicrobial resistance
    Challenges in tracking horizontal gene transfer of antimicrobial...
    Focusing on the urgent clinical problem of increasing carbapenem resistance in Enterobacteriaceae we have been evaluating detection methods in clinical microbiology and molecular transmissio...
    Speaker: Amy Mathers, MD, D(ABMM)
    Presented at: Microbiology Week Virtual Event Series 2020
    4
    SEP 09, 2020 | 9:00 AM
    Keynote Presentation: Human Monoclonal Antibodies for Emerging Agents
    Keynote Presentation: Human Monoclonal Antibodies for Emerging...
    Epidemics are occurring at an increasing pace and scale. Our laboratory group has developed platform technologies for discovery of broad and potent neutralizing antibodies for many emerging...
    Speaker: James Crowe, MD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
     
     
  • SEP 09, 2020 | 7:30 AM
    Using cryo-EM for designing next-gen therapeutics against HIV
    Using cryo-EM for designing next-gen therapeutics against HIV
    HIV currently infects almost 40 million people worldwide. The virus is responsible for ~2 million new infections per year and ~1 million deaths. Like all retroviruses, HIV integrates a viral...
    Speaker: Dmitry Lyumkis, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: Thermo Fisher Scientific
    1
    SEP 09, 2020 | 6:00 AM
    Keynote Presentation: Causes and consequences of immune gene diversity in plants
    Keynote Presentation: Causes and consequences of immune gene diversity...
    My group is addressing fundamental questions in evolutionary biology, using both genome- and phenotype-first approaches. A few years ago, we discovered that Arabidopsis thaliana is a great m...
    Speaker: Detlef Weigel, Executive Director
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 09, 2020 | 12:00 AM
    Leveraging SMRT sequencing to resolve complex immune loci
    Leveraging SMRT sequencing to resolve complex immune loci
    The regions of our genome responsible for encoding the genes that regulate our immune response are some of the most complex and polymorphic known. This complexity encompasses multiple types...
    Speaker: Melissa L. Smith, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 09, 2020 | 12:00 AM
    A New KIR Haplotype MSA Empowers Two New Interpretation Algorithms
    A New KIR Haplotype MSA Empowers Two New Interpretation Algorithms
    Human chromosome 19q13.4 contains genes encoding killer-cell immunoglobulin-like receptors (KIR). The region has certain properties such as single nucleotide variation, structural variation,...
    Speaker: David Roe
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 09, 2020 | 12:00 AM
    Environmental stress shapes the evolution of a plant viruses towards a mutualistic relationship with its host
    Environmental stress shapes the evolution of a plant viruses towards...
    Traditionally, virology has been focused in studying the pathogenic effect of viruses. In the recent years, however, this perception is changing and viruses are being studied as mutualistic...
    Speaker: Santiago F. Elena
    Presented at: Microbiology Week Virtual Event Series 2020
    1
     
     
  • SEP 09, 2020 | 12:00 AM
    How Plant Virology Informs Emergence of Zoonotic Viruses Such as SARS-COV-2
    How Plant Virology Informs Emergence of Zoonotic Viruses Such...
    The statement by Dimitri Ivanovsky in 1882 that "the sap of leaves infected with tobacco mosaic disease retains its infectious properties even after filtration through Chamberland filte...
    Speaker: Michael Goodin, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    3
    SEP 08, 2020 | 11:00 PM
    Deep Learning by Analogy: Applying Text and Image Processing Techniques to Sequence Analysis
    Deep Learning by Analogy: Applying Text and Image Processing Techniques...
    Over the past five years there has been an explosion of research the deep learning field. Companies like Google, Facebook, and OpenAI have created neural networks that are significantly more...
    Speaker: Will Dampier, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 11:00 PM
    Applications of Machine Learning to Predict Clinical Provenance of Haemophilus influenzae
    Applications of Machine Learning to Predict Clinical Provenance...
    Background: Haemophilus influenzae is the causative agent of multiple human disease conditions among multiple sites in the human body. Underlying genetic mechanisms are elusive, particularly...
    Speaker: Joshua Earl, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 11:00 PM
    Recombination, lineage-specific mutations and the emergence of SARS-CoV-2
    Recombination, lineage-specific mutations and the emergence of...
    The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
    Speaker: Ioan Filip, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
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