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    Isotope

    Isotope: are variants of a particular chemical element which differ in neutron number and in nucleon number. All isotopes of a given element have the same number of protons but different numbers of neutrons in each atom. Isotopes differ in mass number and the physical properties of atoms, do depend on mass. This is what enables isotopes to be separated from one another.

    Webinars

    • OCT 01, 2020 | 11:00 AM
      Vitamin B6 Addiction in Acute Myeloid Leukemia
      Vitamin B6 Addiction in Acute Myeloid Leukemia
      Date: October 1, 2020 Time: 10:00am (PTD), 1:00pm (EDT) Cancer cells rely on altered metabolism to support their proliferation. We performed a CRISPR/Cas9 functional genomic screen targeting...
      Speaker: Justin Cross
      Sponsored By: Agilent
      12 1
      SEP 23, 2020 | 8:00 AM
      CAR T-Cell Immunotherapy of Solid Tumors - Learning from the Clinic and Lab in Parallel
      CAR T-Cell Immunotherapy of Solid Tumors - Learning from the Clinic...
      Date: Time: Over the last couple of years, it has become apparent that affinity-tuned CAR T cells display enhanced expansion and prolonged persistence in patients and that this strategy can...
      Speaker: John Maher, PhD , Rogier Reijmers, PhD
      LUMICKS
      9 1
      AUG 06, 2020 | 12:00 AM
      Liquid phase Peak Force Infrared Microscopy: Super-resolution Infrared Microscopy in the Aqueous Phase
      Liquid phase Peak Force Infrared Microscopy: Super-resolution...
      Infrared spectroscopy and microscopy directly couples to molecular functional groups, providing chemical information without extrinsic labels. However, conventional infrared spectroscopy and...
      Speaker: Xiaoji Xu, PhD
      Presented at: 2020 Beckman Symposium
      1
      OCT 24, 2019 | 1:30 PM
      Characterization of Biotherapeutics by Chemometric and Machine Learning Analysis of NMR Spectra
      Characterization of Biotherapeutics by Chemometric and Machine...
      With annual sales exceeding $145 billion, growth of biologic therapeutics is outpacing that of small-molecule drugs, and the development, manufacture, and delivery of biologics presents very...
      Speaker: Frank Delaglio, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2019
      4 1
      OCT 24, 2019 | 7:30 AM
      Quantitation of Mycotoxins in Food Matrices Comparing Stable Isotope Dilution Assay (SIDA) with Matrix Matched Calibration Methods by LC-MS/MS
      Quantitation of Mycotoxins in Food Matrices Comparing Stable Isotope...
      Mycotoxins are secondary fungal metabolites produced by mold that may be found in food or feed. They can cause severe health problems in humans and animals, and can result in significant econ...
      Speaker: Dan Li, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2019
      2
      MAR 20, 2019 | 8:00 AM
      Manipulating trypsin digestion conditions to accelerate digestion and improve signal intensity for building a protein-based mass spectrometric assay
      Manipulating trypsin digestion conditions to accelerate digestion...
      DATE: March 20, 2019TIME:  8:00am PDTMultiple aspects need to be considered when building a protein-based mass spectrometric assay such as the selection of signature peptide...
      Speaker: Dr. Yuzi (Emma) Zheng
      Sponsored By: Agilent
      3
      MAR 05, 2019 | 10:00 AM
      Comprehensive Capture of Human Neuropathology by Multiplexed Ion Beam Imaging (MIBI)
      Comprehensive Capture of Human Neuropathology by Multiplexed Ion...
      DATE: March 5, 2019TIME:  10:00am PSTSingle cell analysis, starting with the earliest low parameter fluorescent experiments, helped define the major cell subsets of human ce...
      Speaker: Sean Bendall, PhD
      Sponsored By: IONpath
      2 1
      OCT 30, 2018 | 10:00 AM
      Post-translational Modifications and Data-Independent Acquisitions - Challenges and Opportunities
      Post-translational Modifications and Data-Independent Acquisitions...
      DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
      Speaker: Birgit Schilling, PhD , Matthew Stokes, PhD
      Sponsored By: Cell Signaling Technology
      5
      OCT 25, 2018 | 7:30 AM
      Analytical Approaches to Advance Alzheimer's Disease Research
      Analytical Approaches to Advance Alzheimer's Disease Research
      Alzheimer’s disease is becoming a public health crisis as the anticipated number of sufferers is expected to rise to 15 million in the next 30 years, at least in the US. These numbers a...
      Speaker: Rena Robinson, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2018
      1
      OCT 24, 2018 | 10:30 AM
      Chemometric Methods for Analysis of 2D 1H-13C Methyl NMR Spectra of Monoclonal Antibodies for Higher Order Structure Characterization
      Chemometric Methods for Analysis of 2D 1H-13C Methyl NMR Spectra...
      Two-dimensional (2D) 1H-13C methyl correlated NMR is increasingly being recognized as a powerful tool to characterize the higher order structure (HOS) of monoclonal antibody (mAb) therapeutic...
      Speaker: Luke Arbogast, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2018
      1
      SEP 27, 2017 | 10:30 AM
      Combining Seahorse XF analysis with stable isotope tracing to reveal novel drug targets for metabolic and neurodegenerative disease
      Combining Seahorse XF analysis with stable isotope tracing to...
      To study cell metabolism, our laboratory has found it exceedingly informative to integrate Agilent Seahorse XF Analyzers with mass spectrometry-based measurements of metabolomics and stable i...
      Speaker: Ajit Divakaruni, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      Sponsored By: Agilent
      1
      JAN 27, 2017 | 4:00 AM
      WEBINAR: Highly Multiplexed Single Cell Analysis Of Tumor Heterogeneity Through Time and Space by Mass Cytometry
      WEBINAR: Highly Multiplexed Single Cell Analysis Of Tumor Heterogeneity...
      DATE: January 27, 2017TIME: 4:00am PT, 7:00am ET, 1:00pm CETThe study of the tumor ecosystem and its cell-to-cell communications is essential to enable an understanding of tumor biology...
      Speaker: Bernd Bodenmiller, PhD , Randall Wetzel, PhD
      Sponsored By: Cell Signaling Technology, Cell Signaling Technology
      16
      NOV 11, 2015 | 7:30 AM
      Keynote: Evolution of Standardization in Laboratory Medicine
      Keynote: Evolution of Standardization in Laboratory Medicine
      There is agreement among clinicians that laboratory analyses are indispensable for correct diagnosis of disease, therapy, and patient monitoring. It is evident that laboratory data should be...
      Speaker: Linda Thienpont, PhD, PHARM, Clinical Chemist
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
      4
      OCT 30, 2014 | 3:00 PM
      Probing cancer metabolism using isotope tracers to identify therapeutic targets
      Probing cancer metabolism using isotope tracers to identify therapeutic...
      Oncogenic mutations in isocitrate dehydrogenase 1 (IDH1) or 2 (IDH2) compromise their normal activity and induce NADPH-dependent (D)2-hydroxyglutarate (2HG) production within the cytosol or m...
      Speaker: Christian Metallo, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 29, 2014 | 12:00 PM
      Improving the Robustness and Reproducibility of Quantitative Proteomics
      Improving the Robustness and Reproducibility of Quantitative Proteomics
      Proteomics technology has improved dramatically over the last decade. The technology developments have largely been directed around instrument hardware, where instruments have been developed...
      Speaker: Michael MacCoss, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      6
    OCT 01, 2020 | 11:00 AM
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    Date: October 1, 2020 Time: 10:00am (PTD), 1:00pm (EDT) Cancer cells rely on altered metabolism to support their proliferation. We performed a CRISPR/Cas9 functional genomic screen targeting...
    Speaker: Justin Cross
    Sponsored By: Agilent
    12 1
    SEP 23, 2020 | 8:00 AM
    CAR T-Cell Immunotherapy of Solid Tumors - Learning from the Clinic and Lab in Parallel
    CAR T-Cell Immunotherapy of Solid Tumors - Learning from the Clinic...
    Date: Time: Over the last couple of years, it has become apparent that affinity-tuned CAR T cells display enhanced expansion and prolonged persistence in patients and that this strategy can...
    Speaker: John Maher, PhD , Rogier Reijmers, PhD
    LUMICKS
    9 1
    AUG 06, 2020 | 12:00 AM
    Liquid phase Peak Force Infrared Microscopy: Super-resolution Infrared Microscopy in the Aqueous Phase
    Liquid phase Peak Force Infrared Microscopy: Super-resolution...
    Infrared spectroscopy and microscopy directly couples to molecular functional groups, providing chemical information without extrinsic labels. However, conventional infrared spectroscopy and...
    Speaker: Xiaoji Xu, PhD
    Presented at: 2020 Beckman Symposium
    1
    OCT 24, 2019 | 1:30 PM
    Characterization of Biotherapeutics by Chemometric and Machine Learning Analysis of NMR Spectra
    Characterization of Biotherapeutics by Chemometric and Machine...
    With annual sales exceeding $145 billion, growth of biologic therapeutics is outpacing that of small-molecule drugs, and the development, manufacture, and delivery of biologics presents very...
    Speaker: Frank Delaglio, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2019
    4 1
    OCT 24, 2019 | 7:30 AM
    Quantitation of Mycotoxins in Food Matrices Comparing Stable Isotope Dilution Assay (SIDA) with Matrix Matched Calibration Methods by LC-MS/MS
    Quantitation of Mycotoxins in Food Matrices Comparing Stable Isotope...
    Mycotoxins are secondary fungal metabolites produced by mold that may be found in food or feed. They can cause severe health problems in humans and animals, and can result in significant econ...
    Speaker: Dan Li, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2019
    2
     
     
  • MAR 20, 2019 | 8:00 AM
    Manipulating trypsin digestion conditions to accelerate digestion and improve signal intensity for building a protein-based mass spectrometric assay
    Manipulating trypsin digestion conditions to accelerate digestion...
    DATE: March 20, 2019TIME:  8:00am PDTMultiple aspects need to be considered when building a protein-based mass spectrometric assay such as the selection of signature peptide...
    Speaker: Dr. Yuzi (Emma) Zheng
    Sponsored By: Agilent
    3
    MAR 05, 2019 | 10:00 AM
    Comprehensive Capture of Human Neuropathology by Multiplexed Ion Beam Imaging (MIBI)
    Comprehensive Capture of Human Neuropathology by Multiplexed Ion...
    DATE: March 5, 2019TIME:  10:00am PSTSingle cell analysis, starting with the earliest low parameter fluorescent experiments, helped define the major cell subsets of human ce...
    Speaker: Sean Bendall, PhD
    Sponsored By: IONpath
    2 1
    OCT 30, 2018 | 10:00 AM
    Post-translational Modifications and Data-Independent Acquisitions - Challenges and Opportunities
    Post-translational Modifications and Data-Independent Acquisitions...
    DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
    Speaker: Birgit Schilling, PhD , Matthew Stokes, PhD
    Sponsored By: Cell Signaling Technology
    5
    OCT 25, 2018 | 7:30 AM
    Analytical Approaches to Advance Alzheimer's Disease Research
    Analytical Approaches to Advance Alzheimer's Disease Research
    Alzheimer’s disease is becoming a public health crisis as the anticipated number of sufferers is expected to rise to 15 million in the next 30 years, at least in the US. These numbers a...
    Speaker: Rena Robinson, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2018
    1
    OCT 24, 2018 | 10:30 AM
    Chemometric Methods for Analysis of 2D 1H-13C Methyl NMR Spectra of Monoclonal Antibodies for Higher Order Structure Characterization
    Chemometric Methods for Analysis of 2D 1H-13C Methyl NMR Spectra...
    Two-dimensional (2D) 1H-13C methyl correlated NMR is increasingly being recognized as a powerful tool to characterize the higher order structure (HOS) of monoclonal antibody (mAb) therapeutic...
    Speaker: Luke Arbogast, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2018
    1
     
     
  • SEP 27, 2017 | 10:30 AM
    Combining Seahorse XF analysis with stable isotope tracing to reveal novel drug targets for metabolic and neurodegenerative disease
    Combining Seahorse XF analysis with stable isotope tracing to...
    To study cell metabolism, our laboratory has found it exceedingly informative to integrate Agilent Seahorse XF Analyzers with mass spectrometry-based measurements of metabolomics and stable i...
    Speaker: Ajit Divakaruni, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    Sponsored By: Agilent
    1
    JAN 27, 2017 | 4:00 AM
    WEBINAR: Highly Multiplexed Single Cell Analysis Of Tumor Heterogeneity Through Time and Space by Mass Cytometry
    WEBINAR: Highly Multiplexed Single Cell Analysis Of Tumor Heterogeneity...
    DATE: January 27, 2017TIME: 4:00am PT, 7:00am ET, 1:00pm CETThe study of the tumor ecosystem and its cell-to-cell communications is essential to enable an understanding of tumor biology...
    Speaker: Bernd Bodenmiller, PhD , Randall Wetzel, PhD
    Sponsored By: Cell Signaling Technology, Cell Signaling Technology
    16
    NOV 11, 2015 | 7:30 AM
    Keynote: Evolution of Standardization in Laboratory Medicine
    Keynote: Evolution of Standardization in Laboratory Medicine
    There is agreement among clinicians that laboratory analyses are indispensable for correct diagnosis of disease, therapy, and patient monitoring. It is evident that laboratory data should be...
    Speaker: Linda Thienpont, PhD, PHARM, Clinical Chemist
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
    4
    OCT 30, 2014 | 3:00 PM
    Probing cancer metabolism using isotope tracers to identify therapeutic targets
    Probing cancer metabolism using isotope tracers to identify therapeutic...
    Oncogenic mutations in isocitrate dehydrogenase 1 (IDH1) or 2 (IDH2) compromise their normal activity and induce NADPH-dependent (D)2-hydroxyglutarate (2HG) production within the cytosol or m...
    Speaker: Christian Metallo, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
    OCT 29, 2014 | 12:00 PM
    Improving the Robustness and Reproducibility of Quantitative Proteomics
    Improving the Robustness and Reproducibility of Quantitative Proteomics
    Proteomics technology has improved dramatically over the last decade. The technology developments have largely been directed around instrument hardware, where instruments have been developed...
    Speaker: Michael MacCoss, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    6
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