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    Mathematical models

    Mathematical models are systems consisting of a set of equations used to describe a set of variables. Pie charts, tables, line graphs, chemical formulas, and diagrams are examples of mathematical models.

    Webinars

    • DEC 03, 2020 | 9:00 AM
      Transmission Dynamics of SARS-CoV-2: Inference and Projection
      Transmission Dynamics of SARS-CoV-2: Inference and Projection
      Dynamic models of infectious disease systems are often used to study the epidemiological characteristics of disease outbreaks, the ecological mechanisms and environmental conditions affectin...
      Speaker: Jeffrey Shaman
      Presented at: Coronavirus Series
      3
      SEP 09, 2020 | 12:00 AM
      Environmental stress shapes the evolution of a plant viruses towards a mutualistic relationship with its host
      Environmental stress shapes the evolution of a plant viruses towards...
      Traditionally, virology has been focused in studying the pathogenic effect of viruses. In the recent years, however, this perception is changing and viruses are being studied as mutualistic...
      Speaker: Santiago F. Elena
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 11:00 PM
      Recombination, lineage-specific mutations and the emergence of SARS-CoV-2
      Recombination, lineage-specific mutations and the emergence of...
      The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
      Speaker: Ioan Filip, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      AUG 06, 2020 | 12:00 AM
      More Exquisitely Adapted Species Have Higher Structural Disorder in Vertebrate Protein Domains
      More Exquisitely Adapted Species Have Higher Structural Disorder...
      Protein structural disorder helps avoid misfolding and aggregation, but in impeding protein folding might also impede function. The balance between these two selective pressures on protein b...
      Speaker: Catherine Weibel
      Presented at: 2020 Beckman Symposium
      1
      JUN 16, 2020 | 8:00 AM
      Measuring molecular interactions by multi-wavelength analytical ultracentrifugation
      Measuring molecular interactions by multi-wavelength analytical...
      DATE: June 16, 2020 TIME: 8:00am PT Multi-wavelength analysis of hydrodynamic data collected on the latest analytical ultracentrifugation instruments provides additional resolution and insig...
      Speaker: Borries Demeler, PhD
      Sponsored By: Beckman Coulter Life Sciences
      22 1
      JUN 09, 2020 | 6:00 AM
      Smart Plastics: Improving qPCR reliability & reproducibility
      Smart Plastics: Improving qPCR reliability & reproducibility
      DATE: June 9, 2020 TIME: 6am PT, 9am ET, 3pm CEST The importance of disposable plastic consumables and their overall impact on the experimental workflow of qPCR has been taken into considera...
      Speaker: Michael Pfaffl, Ph.D. , Tim Schommartz, PhD , Rafal Grzeskowiak, PhD
      Sponsored By: Eppendorf
      39
      APR 08, 2020 | 12:00 AM
      Macroscopic Modeling of Bioreactors for Recombinant Protein Producing Pichia pastoris in Defined Medium
      Macroscopic Modeling of Bioreactors for Recombinant Protein Producing...
      Bioreactor modeling can inform understanding of cellular metabolism—including aspects of growth kinetics, productivity, media consumption, and metabolite secretion—and can be use...
      Speaker: Moo Sun Hong, MS
      Presented at: BioProcessing Virtual Event Series 2020
      2
      MAR 11, 2020 | 12:00 PM
      PANEL: Cracking a Neural Circuit's Function Through High-Resolution Physiology, Connectomics, and Computational Modeling
      PANEL: Cracking a Neural Circuit's Function Through High-Resolution...
      Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
      Speaker: Emre Aksay, PhD , Mark Goldman, PhD , Sebastian Seung, PhD , Ashwin Vishwanathan, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1 1
      MAR 11, 2020 | 10:30 AM
      PANEL: The Berghia Brain Project: A Team Approach to Understanding Whole-Brain Control of State-Dependent, Motivated Behaviors
      PANEL: The Berghia Brain Project: A Team Approach to Understanding...
      The neural basis of simple rhythmic and reflexive behaviors such as swimming and gill withdrawal have been successfully studied in nudibranchs and other gastropod molluscs because the brains...
      Speaker: Paul Katz, PhD , Jeff Lichtman, MD, PhD , William Frost, PhD , Deidre Lyons, PhD , Vince Lyzinski, PhD, B.Sc, M.Sc, M.Sc.E.
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 6:00 AM
      PANEL: Sensorimotor Processing, Decision Making, and Internal States: Towards a Realistic Multiscale Circuit Model of the Larval Zebrafish Brain
      PANEL: Sensorimotor Processing, Decision Making, and Internal...
      We present here a framework to generate a realistic multiscale circuit model of the larval zebrafish brain – the multiscale virtual fish (MVF). The model will be based on algorithms in...
      Speaker: Florian Engert, PhD , Jeff Lichtman, MD, PhD , Haim Sompolinsky
      Presented at: Neuroscience Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Multi-region Neural Network Models of Adaptive and Maladaptive Learning in the Brain
      Multi-region Neural Network Models of Adaptive and Maladaptive...
      In Andalman et al, 2018, we explored the activity of over 10,000 neurons across more than 15 regions imaged simultaneously in larval zebrafish in a novel behavioral challenge paradigm. Compl...
      Speaker: Kanaka Rajan, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 14, 2019 | 10:00 AM
      Identifying Pattern Transitions of Mind and Brain in Psychotherapy: The Nonlinear Dynamics of Human Change Processes
      Identifying Pattern Transitions of Mind and Brain in Psychotherapy:...
      An actual way of understanding complex systems in psychology and psychiatry is by building mathematical models on the functioning of mental, behavioral, or neural systems (computational syste...
      Speaker: Günter Schiepek, PhD
      Presented at: Neuroscience Virtual Event Series 2019
      2
      MAR 13, 2019 | 2:40 PM
      Clinical Updates: Closed Loop Deep Brain Stimulation in Parkinson's Disease Using Patient Specific Biomarkers and Therapeutic Windows
      Clinical Updates: Closed Loop Deep Brain Stimulation in Parkinson's...
      Deep brain stimulation (DBS) is an established therapy for cardinal motor signs and medication-related complications in Parkinson’s disease (PD). Current DBS therapy is limited to &ldqu...
      Speaker: Helen Bronte-Stewart, MD, MS
      Presented at: Neuroscience Virtual Event Series 2019
      1
      FEB 27, 2019 | 6:00 AM
      Biomarkers of Aging
      Biomarkers of Aging
      Ageing is a complex process that has been observed in all biological systems at every level of organisation. Some anti-ageing interventions have demonstrated life-extending effects in model o...
      Speaker: Alex Zhavoronkov, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      OCT 11, 2018 | 10:30 AM
      Drug Targeting for Inflammatory Breast Cancer
      Drug Targeting for Inflammatory Breast Cancer
      Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
      Speaker: Kevin Williams, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 11, 2018 | 9:00 AM
      Destabilization and Degradation of MYC: More Ways Than One
      Destabilization and Degradation of MYC: More Ways Than One
      The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
      Speaker: Jason De Melo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 7:30 AM
      Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
      Keynote Presentation: In Advanced Cancers Curative Therapies Must...
      In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
      Speaker: Krastan Blagoev, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 6:00 AM
      Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
      Revealing the Hidden Landscape of Structural Variants in Cancer...
      PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
      Speaker: Jonas Korlach, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
      Speaker: Jerome Galon, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Sample to Insight:  Everything You Need to Know About RNA Sequencing
      Sample to Insight: Everything You Need to Know About RNA Sequencing
      RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
      Speaker: Jonathan Shaffer, PhD, MBA
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      OCT 10, 2018 | 9:00 AM
      Understanding Cancer Through Whole-Genome Screening
      Understanding Cancer Through Whole-Genome Screening
      High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
      Speaker: Andrew Ravanelli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: MilliporeSigma
      5
      OCT 10, 2018 | 9:00 AM
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
      In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
      Speaker: Paul Sondel, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 7:30 AM
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
      Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
      Speaker: Karin Rodland, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 10, 2018 | 6:00 AM
      Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
      Precise Detection of T-Cell Receptors Using RNAseq With Unique...
      Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
      Speaker: Samuel Rulli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
    DEC 03, 2020 | 9:00 AM
    Transmission Dynamics of SARS-CoV-2: Inference and Projection
    Transmission Dynamics of SARS-CoV-2: Inference and Projection
    Dynamic models of infectious disease systems are often used to study the epidemiological characteristics of disease outbreaks, the ecological mechanisms and environmental conditions affectin...
    Speaker: Jeffrey Shaman
    Presented at: Coronavirus Series
    3
    SEP 09, 2020 | 12:00 AM
    Environmental stress shapes the evolution of a plant viruses towards a mutualistic relationship with its host
    Environmental stress shapes the evolution of a plant viruses towards...
    Traditionally, virology has been focused in studying the pathogenic effect of viruses. In the recent years, however, this perception is changing and viruses are being studied as mutualistic...
    Speaker: Santiago F. Elena
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 11:00 PM
    Recombination, lineage-specific mutations and the emergence of SARS-CoV-2
    Recombination, lineage-specific mutations and the emergence of...
    The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
    Speaker: Ioan Filip, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    AUG 06, 2020 | 12:00 AM
    More Exquisitely Adapted Species Have Higher Structural Disorder in Vertebrate Protein Domains
    More Exquisitely Adapted Species Have Higher Structural Disorder...
    Protein structural disorder helps avoid misfolding and aggregation, but in impeding protein folding might also impede function. The balance between these two selective pressures on protein b...
    Speaker: Catherine Weibel
    Presented at: 2020 Beckman Symposium
    1
    JUN 16, 2020 | 8:00 AM
    Measuring molecular interactions by multi-wavelength analytical ultracentrifugation
    Measuring molecular interactions by multi-wavelength analytical...
    DATE: June 16, 2020 TIME: 8:00am PT Multi-wavelength analysis of hydrodynamic data collected on the latest analytical ultracentrifugation instruments provides additional resolution and insig...
    Speaker: Borries Demeler, PhD
    Sponsored By: Beckman Coulter Life Sciences
    22 1
     
     
  • JUN 09, 2020 | 6:00 AM
    Smart Plastics: Improving qPCR reliability & reproducibility
    Smart Plastics: Improving qPCR reliability & reproducibility
    DATE: June 9, 2020 TIME: 6am PT, 9am ET, 3pm CEST The importance of disposable plastic consumables and their overall impact on the experimental workflow of qPCR has been taken into considera...
    Speaker: Michael Pfaffl, Ph.D. , Tim Schommartz, PhD , Rafal Grzeskowiak, PhD
    Sponsored By: Eppendorf
    39
    APR 08, 2020 | 12:00 AM
    Macroscopic Modeling of Bioreactors for Recombinant Protein Producing Pichia pastoris in Defined Medium
    Macroscopic Modeling of Bioreactors for Recombinant Protein Producing...
    Bioreactor modeling can inform understanding of cellular metabolism—including aspects of growth kinetics, productivity, media consumption, and metabolite secretion—and can be use...
    Speaker: Moo Sun Hong, MS
    Presented at: BioProcessing Virtual Event Series 2020
    2
    MAR 11, 2020 | 12:00 PM
    PANEL: Cracking a Neural Circuit's Function Through High-Resolution Physiology, Connectomics, and Computational Modeling
    PANEL: Cracking a Neural Circuit's Function Through High-Resolution...
    Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
    Speaker: Emre Aksay, PhD , Mark Goldman, PhD , Sebastian Seung, PhD , Ashwin Vishwanathan, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1 1
    MAR 11, 2020 | 10:30 AM
    PANEL: The Berghia Brain Project: A Team Approach to Understanding Whole-Brain Control of State-Dependent, Motivated Behaviors
    PANEL: The Berghia Brain Project: A Team Approach to Understanding...
    The neural basis of simple rhythmic and reflexive behaviors such as swimming and gill withdrawal have been successfully studied in nudibranchs and other gastropod molluscs because the brains...
    Speaker: Paul Katz, PhD , Jeff Lichtman, MD, PhD , William Frost, PhD , Deidre Lyons, PhD , Vince Lyzinski, PhD, B.Sc, M.Sc, M.Sc.E.
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 11, 2020 | 6:00 AM
    PANEL: Sensorimotor Processing, Decision Making, and Internal States: Towards a Realistic Multiscale Circuit Model of the Larval Zebrafish Brain
    PANEL: Sensorimotor Processing, Decision Making, and Internal...
    We present here a framework to generate a realistic multiscale circuit model of the larval zebrafish brain – the multiscale virtual fish (MVF). The model will be based on algorithms in...
    Speaker: Florian Engert, PhD , Jeff Lichtman, MD, PhD , Haim Sompolinsky
    Presented at: Neuroscience Virtual Event Series 2020
    1
     
     
  • JAN 01, 2020 | 6:00 AM
    Multi-region Neural Network Models of Adaptive and Maladaptive Learning in the Brain
    Multi-region Neural Network Models of Adaptive and Maladaptive...
    In Andalman et al, 2018, we explored the activity of over 10,000 neurons across more than 15 regions imaged simultaneously in larval zebrafish in a novel behavioral challenge paradigm. Compl...
    Speaker: Kanaka Rajan, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 14, 2019 | 10:00 AM
    Identifying Pattern Transitions of Mind and Brain in Psychotherapy: The Nonlinear Dynamics of Human Change Processes
    Identifying Pattern Transitions of Mind and Brain in Psychotherapy:...
    An actual way of understanding complex systems in psychology and psychiatry is by building mathematical models on the functioning of mental, behavioral, or neural systems (computational syste...
    Speaker: Günter Schiepek, PhD
    Presented at: Neuroscience Virtual Event Series 2019
    2
    MAR 13, 2019 | 2:40 PM
    Clinical Updates: Closed Loop Deep Brain Stimulation in Parkinson's Disease Using Patient Specific Biomarkers and Therapeutic Windows
    Clinical Updates: Closed Loop Deep Brain Stimulation in Parkinson's...
    Deep brain stimulation (DBS) is an established therapy for cardinal motor signs and medication-related complications in Parkinson’s disease (PD). Current DBS therapy is limited to &ldqu...
    Speaker: Helen Bronte-Stewart, MD, MS
    Presented at: Neuroscience Virtual Event Series 2019
    1
    FEB 27, 2019 | 6:00 AM
    Biomarkers of Aging
    Biomarkers of Aging
    Ageing is a complex process that has been observed in all biological systems at every level of organisation. Some anti-ageing interventions have demonstrated life-extending effects in model o...
    Speaker: Alex Zhavoronkov, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    OCT 11, 2018 | 10:30 AM
    Drug Targeting for Inflammatory Breast Cancer
    Drug Targeting for Inflammatory Breast Cancer
    Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
    Speaker: Kevin Williams, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
     
     
  • OCT 11, 2018 | 9:00 AM
    Destabilization and Degradation of MYC: More Ways Than One
    Destabilization and Degradation of MYC: More Ways Than One
    The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
    Speaker: Jason De Melo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 7:30 AM
    Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
    Keynote Presentation: In Advanced Cancers Curative Therapies Must...
    In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
    Speaker: Krastan Blagoev, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 6:00 AM
    Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
    Revealing the Hidden Landscape of Structural Variants in Cancer...
    PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
    Speaker: Jonas Korlach, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 12:00 PM
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
    Speaker: Jerome Galon, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 12:00 PM
    Sample to Insight:  Everything You Need to Know About RNA Sequencing
    Sample to Insight: Everything You Need to Know About RNA Sequencing
    RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
    Speaker: Jonathan Shaffer, PhD, MBA
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
     
     
  • OCT 10, 2018 | 9:00 AM
    Understanding Cancer Through Whole-Genome Screening
    Understanding Cancer Through Whole-Genome Screening
    High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
    Speaker: Andrew Ravanelli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: MilliporeSigma
    5
    OCT 10, 2018 | 9:00 AM
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
    In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
    Speaker: Paul Sondel, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 7:30 AM
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
    Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
    Speaker: Karin Rodland, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 10, 2018 | 6:00 AM
    Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
    Precise Detection of T-Cell Receptors Using RNAseq With Unique...
    Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
    Speaker: Samuel Rulli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
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