Mutagenesis
Mutagenesis: is a process by which the genetic information of an organism is changed, resulting in a mutation. It may occur spontaneously in nature, or as a result of exposure to mutagens. It can also be achieved experimentally using laboratory procedures.
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JAN 31, 2019 7:30 AM PSTC.E. CREDITS
JAN 31, 2019 7:30 AM PSTProdrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...Speaker: A.C. Matin, PhDPresented at:BioProcessing 2019OCT 11, 2018 1:30 PM PDTC.E. CREDITS
OCT 11, 2018 1:30 PM PDTRecent work has identified epigenomic features of distal regulatory elements to be dynamic and defining indicators of cellular specification and transformation. Of particular relevance is our...Speaker: Martin Hirst, PhDPresented at:Cancer Research & Oncology 2018OCT 11, 2018 1:30 PM PDTC.E. CREDITS
OCT 11, 2018 1:30 PM PDTAs the most common female malignancy, breast cancer is the most likely reason that a woman will die of cancer around the world. Breast cancer mortality has dropped in the U.S. by 35% since 19...Speaker: Benjamin Anderson, MDPresented at:Cancer Research & Oncology 2018OCT 11, 2018 12:00 PM PDTC.E. CREDITS
OCT 11, 2018 12:00 PM PDTAlthough targeted therapies often elicit profound initial patient responses, these effects are transient due to residual disease leading to acquired resistance. How tumors transition between...Speaker: Khyati Shah, PhDPresented at:Cancer Research & Oncology 2018OCT 11, 2018 12:00 PM PDTC.E. CREDITS
OCT 11, 2018 12:00 PM PDTLung cancer is the leading cause of cancer-related mortality worldwide. Large-scale sequencing studies have revealed the complex genomic landscape of NSCLC and genomic differences between lun...Speaker: Nicholas McGranahan, PhDPresented at:Cancer Research & Oncology 2018OCT 11, 2018 10:30 AM PDTC.E. CREDITS
OCT 11, 2018 10:30 AM PDTAntibodies are extremely valuable and ubiquitous tools in life science research, but in spite of their widespread use in immunoassays over the past several decades, there is still a lack of u...Speaker: Chandra Mohan, PhDPresented at:Cancer Research & Oncology 2018Sponsored By: MilliporeSigmaOCT 11, 2018 10:30 AM PDTC.E. CREDITS
OCT 11, 2018 10:30 AM PDTTwo projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...Speaker: Kevin Williams, PhDPresented at:Cancer Research & Oncology 2018OCT 11, 2018 9:00 AM PDTC.E. CREDITS
OCT 11, 2018 9:00 AM PDTThe oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...Speaker: Jason De Melo, PhDPresented at:Cancer Research & Oncology 2018OCT 11, 2018 9:00 AM PDTC.E. CREDITS
OCT 11, 2018 9:00 AM PDTIn the last two decades, large amount of next-generation sequencing (NGS) and -omics data has been generated in the field of immuno-oncology. Generating hypotheses by analyzing hundreds if no...Speaker: Devendra Mistry, PhDPresented at:Cancer Research & Oncology 2018Sponsored By: QIAGENOCT 11, 2018 7:30 AM PDTC.E. CREDITS
OCT 11, 2018 7:30 AM PDTIn the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...Speaker: Krastan Blagoev, PhDPresented at:Cancer Research & Oncology 2018OCT 11, 2018 6:00 AM PDTC.E. CREDITS
OCT 11, 2018 6:00 AM PDTPacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...Speaker: Jonas Korlach, PhDPresented at:Cancer Research & Oncology 2018OCT 10, 2018 12:00 PM PDTC.E. CREDITS
OCT 10, 2018 12:00 PM PDTRNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...Speaker: Jonathan Shaffer, MBA, PhDPresented at:Cancer Research & Oncology 2018Sponsored By: QIAGENOCT 10, 2018 12:00 PM PDTC.E. CREDITS
OCT 10, 2018 12:00 PM PDTTo date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...Speaker: Jerome Galon, PhDPresented at:Cancer Research & Oncology 2018OCT 10, 2018 10:30 AM PDTC.E. CREDITS
OCT 10, 2018 10:30 AM PDTPancreatic tumors are dynamic pseudo-organs that contain numerous cell types interacting to create unique physiology. A typical pancreatic tumor is made up largely of stromal fibroblasts and...Speaker: Costas A. Lyssiotis, PhDPresented at:Cancer Research & Oncology 2018Sponsored By: AgilentOCT 10, 2018 10:30 AM PDTC.E. CREDITS
OCT 10, 2018 10:30 AM PDTThe microbiome signatures in the context of gynecologic cancers (endometrial and ovarian) and the potential for their clinical use will be discussed. The use of microfluidic technologies to i...Speaker: Marina Walther-Antonio, PhDPresented at:Cancer Research & Oncology 2018OCT 10, 2018 9:00 AM PDTC.E. CREDITS
OCT 10, 2018 9:00 AM PDTIn prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...Speaker: Paul Sondel, MD, PhDPresented at:Cancer Research & Oncology 2018OCT 10, 2018 9:00 AM PDTC.E. CREDITS
OCT 10, 2018 9:00 AM PDTHigh-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance. Millipor...Speaker: Andrew Ravanelli, PhDPresented at:Cancer Research & Oncology 2018Sponsored By: MilliporeSigmaOCT 10, 2018 7:30 AM PDTC.E. CREDITS
OCT 10, 2018 7:30 AM PDTMolecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...Speaker: Karin Rodland, PhDPresented at:Cancer Research & Oncology 2018OCT 10, 2018 6:00 AM PDTC.E. CREDITS
OCT 10, 2018 6:00 AM PDTWith over 265,000 new cases per year and over 50,000 deaths, breast and ovarian cancers represent a significant health burden in the USA. Prior work has demonstrated that CD4 helper T c...Speaker: Keith Knutson, PhDPresented at:Cancer Research & Oncology 2018OCT 10, 2018 6:00 AM PDTC.E. CREDITS
OCT 10, 2018 6:00 AM PDTUnderstanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...Speaker: Samuel Rulli, PhDPresented at:Cancer Research & Oncology 2018Sponsored By: QIAGENAUG 09, 2018 8:00 AM CESTC.E. CREDITS
AUG 09, 2018 8:00 AM CESTDATE: August 9, 2018TIME: 8:00am PDT, 11:00am EDT Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive...Speaker: Nicole de Leeuw, PhD , Kristina Cusmano-Ozog, MDSponsored By: Thermo Fisher Scientific - Applied BiosystemsMAR 14, 2018 10:30 AM PDTC.E. CREDITS
MAR 14, 2018 10:30 AM PDTCRISPR Cas9 nucleases have revolutionized gene editing enabling unprecedented efficiency of targeted mutagenesis. Even with such powerful technology at hand, sophisticated projects, su...Speaker: Jeremy LehmannPresented at:Neuroscience 2018Sponsored By: MilliporeSigmaSEP 19, 2017 10:30 AM PDT
SEP 19, 2017 10:30 AM PDTDATE: September 19, 2017TIME: 10:30am PDT/ 1:30pm EDT/ 7:30pm CESTPart 1 – Cigall Kadoch, Ph.D. (30 min.)Exome- and genome-wide sequencing studies in human cancer have...Speaker: Cigall Kadoch, PhD , Chris Fry, PhDSponsored By: Cell Signaling TechnologySEP 14, 2017 6:00 AM PDT
SEP 14, 2017 6:00 AM PDTA rapidly growing number of viruses of lower eukaryotes have been reported in the past few decades. These have enhanced our understanding of virus evolution and diversity. Simultaneously, som...Speaker: Nobuhiro Suzuki, PhDPresented at:Microbiology & Immunology 2017
JAN 31, 2019
7:30 AM PST
C.E. CREDITS
JAN 31, 2019
7:30 AM PST
Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
Speaker:
A.C. Matin, PhD
Presented at:BioProcessing 2019
OCT 11, 2018
1:30 PM PDT
C.E. CREDITS
OCT 11, 2018
1:30 PM PDT
Recent work has identified epigenomic features of distal regulatory elements to be dynamic and defining indicators of cellular specification and transformation. Of particular relevance is our...
Speaker:
Martin Hirst, PhD
Presented at:Cancer Research & Oncology 2018
OCT 11, 2018
1:30 PM PDT
C.E. CREDITS
OCT 11, 2018
1:30 PM PDT
As the most common female malignancy, breast cancer is the most likely reason that a woman will die of cancer around the world. Breast cancer mortality has dropped in the U.S. by 35% since 19...
Speaker:
Benjamin Anderson, MD
Presented at:Cancer Research & Oncology 2018
OCT 11, 2018
12:00 PM PDT
C.E. CREDITS
OCT 11, 2018
12:00 PM PDT
Although targeted therapies often elicit profound initial patient responses, these effects are transient due to residual disease leading to acquired resistance. How tumors transition between...
Speaker:
Khyati Shah, PhD
Presented at:Cancer Research & Oncology 2018
OCT 11, 2018
12:00 PM PDT
C.E. CREDITS
OCT 11, 2018
12:00 PM PDT
Lung cancer is the leading cause of cancer-related mortality worldwide. Large-scale sequencing studies have revealed the complex genomic landscape of NSCLC and genomic differences between lun...
Speaker:
Nicholas McGranahan, PhD
Presented at:Cancer Research & Oncology 2018
OCT 11, 2018
10:30 AM PDT
C.E. CREDITS
OCT 11, 2018
10:30 AM PDT
Antibodies are extremely valuable and ubiquitous tools in life science research, but in spite of their widespread use in immunoassays over the past several decades, there is still a lack of u...
Speaker:
Chandra Mohan, PhD
Presented at:Cancer Research & Oncology 2018
Sponsored By: MilliporeSigma
OCT 11, 2018
10:30 AM PDT
C.E. CREDITS
OCT 11, 2018
10:30 AM PDT
Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
Speaker:
Kevin Williams, PhD
Presented at:Cancer Research & Oncology 2018
OCT 11, 2018
9:00 AM PDT
C.E. CREDITS
OCT 11, 2018
9:00 AM PDT
The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
Speaker:
Jason De Melo, PhD
Presented at:Cancer Research & Oncology 2018
OCT 11, 2018
9:00 AM PDT
C.E. CREDITS
OCT 11, 2018
9:00 AM PDT
In the last two decades, large amount of next-generation sequencing (NGS) and -omics data has been generated in the field of immuno-oncology. Generating hypotheses by analyzing hundreds if no...
Speaker:
Devendra Mistry, PhD
Presented at:Cancer Research & Oncology 2018
Sponsored By: QIAGEN
OCT 11, 2018
7:30 AM PDT
C.E. CREDITS
OCT 11, 2018
7:30 AM PDT
In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
Speaker:
Krastan Blagoev, PhD
Presented at:Cancer Research & Oncology 2018
OCT 11, 2018
6:00 AM PDT
C.E. CREDITS
OCT 11, 2018
6:00 AM PDT
PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
Speaker:
Jonas Korlach, PhD
Presented at:Cancer Research & Oncology 2018
OCT 10, 2018
12:00 PM PDT
C.E. CREDITS
OCT 10, 2018
12:00 PM PDT
RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
Speaker:
Jonathan Shaffer, MBA, PhD
Presented at:Cancer Research & Oncology 2018
Sponsored By: QIAGEN
OCT 10, 2018
12:00 PM PDT
C.E. CREDITS
OCT 10, 2018
12:00 PM PDT
To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
Speaker:
Jerome Galon, PhD
Presented at:Cancer Research & Oncology 2018
OCT 10, 2018
10:30 AM PDT
C.E. CREDITS
OCT 10, 2018
10:30 AM PDT
Pancreatic tumors are dynamic pseudo-organs that contain numerous cell types interacting to create unique physiology. A typical pancreatic tumor is made up largely of stromal fibroblasts and...
Speaker:
Costas A. Lyssiotis, PhD
Presented at:Cancer Research & Oncology 2018
Sponsored By: Agilent
OCT 10, 2018
10:30 AM PDT
C.E. CREDITS
OCT 10, 2018
10:30 AM PDT
The microbiome signatures in the context of gynecologic cancers (endometrial and ovarian) and the potential for their clinical use will be discussed. The use of microfluidic technologies to i...
Speaker:
Marina Walther-Antonio, PhD
Presented at:Cancer Research & Oncology 2018
OCT 10, 2018
9:00 AM PDT
C.E. CREDITS
OCT 10, 2018
9:00 AM PDT
In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
Speaker:
Paul Sondel, MD, PhD
Presented at:Cancer Research & Oncology 2018
OCT 10, 2018
9:00 AM PDT
C.E. CREDITS
OCT 10, 2018
9:00 AM PDT
High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance. Millipor...
Speaker:
Andrew Ravanelli, PhD
Presented at:Cancer Research & Oncology 2018
Sponsored By: MilliporeSigma
OCT 10, 2018
7:30 AM PDT
C.E. CREDITS
OCT 10, 2018
7:30 AM PDT
Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
Speaker:
Karin Rodland, PhD
Presented at:Cancer Research & Oncology 2018
OCT 10, 2018
6:00 AM PDT
C.E. CREDITS
OCT 10, 2018
6:00 AM PDT
With over 265,000 new cases per year and over 50,000 deaths, breast and ovarian cancers represent a significant health burden in the USA. Prior work has demonstrated that CD4 helper T c...
Speaker:
Keith Knutson, PhD
Presented at:Cancer Research & Oncology 2018
OCT 10, 2018
6:00 AM PDT
C.E. CREDITS
OCT 10, 2018
6:00 AM PDT
Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
Speaker:
Samuel Rulli, PhD
Presented at:Cancer Research & Oncology 2018
Sponsored By: QIAGEN
AUG 09, 2018
8:00 AM CEST
C.E. CREDITS
AUG 09, 2018
8:00 AM CEST
DATE: August 9, 2018TIME: 8:00am PDT, 11:00am EDT Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive...
Speaker:
Nicole de Leeuw, PhD
,
Kristina Cusmano-Ozog, MD
Sponsored By: Thermo Fisher Scientific - Applied Biosystems
MAR 14, 2018
10:30 AM PDT
C.E. CREDITS
MAR 14, 2018
10:30 AM PDT
CRISPR Cas9 nucleases have revolutionized gene editing enabling unprecedented efficiency of targeted mutagenesis. Even with such powerful technology at hand, sophisticated projects, su...
Speaker:
Jeremy Lehmann
Presented at:Neuroscience 2018
Sponsored By: MilliporeSigma
SEP 19, 2017
10:30 AM PDT
SEP 19, 2017
10:30 AM PDT
DATE: September 19, 2017TIME: 10:30am PDT/ 1:30pm EDT/ 7:30pm CESTPart 1 – Cigall Kadoch, Ph.D. (30 min.)Exome- and genome-wide sequencing studies in human cancer have...
Speaker:
Cigall Kadoch, PhD
,
Chris Fry, PhD
Sponsored By: Cell Signaling Technology
SEP 14, 2017
6:00 AM PDT
SEP 14, 2017
6:00 AM PDT
A rapidly growing number of viruses of lower eukaryotes have been reported in the past few decades. These have enhanced our understanding of virus evolution and diversity. Simultaneously, som...
Speaker:
Nobuhiro Suzuki, PhD
Presented at:Microbiology & Immunology 2017
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