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    Mutagenesis

    Mutagenesis: is a process by which the genetic information of an organism is changed, resulting in a mutation. It may occur spontaneously in nature, or as a result of exposure to mutagens. It can also be achieved experimentally using laboratory procedures.

    Webinars

    • NOV 01, 2022 | 10:00 AM
      Flow cytometric gene mutation assay, made possible by immunomagnetic separation, achieves OECD regulatory status
      Flow cytometric gene mutation assay, made possible by immunomagnetic...
      Date: November 01, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 6:00pm (CET) Our laboratory developed the Pig-a gene mutation assay as a means to simply and reliably evaluate the potential mutage...
      Speaker: Jeffrey Bemis, Ph.D. , Joe Ostrand, Ph.D.
      Sponsored By: Miltenyi Biotec
      11
      MAY 26, 2022 | 8:00 AM
      Cell-Free Tools to Revolutionize the DNA Construction Paradigm
      Cell-Free Tools to Revolutionize the DNA Construction Paradigm
      Date: May 26, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST), 12:00am JST The industry still relies heavily on PCR and cell-based cloning. Both are decades old methodologies. However,...
      Speaker: Shige Sasaki , Kazu Isono
      Sponsored By: OriCiro Genomics
      6
      OCT 14, 2021 | 7:00 AM
      Heterologous Protein Engineering and characterization of native regulatory elements  in E. coli using Massively Parallel CRISPR Editing
      Heterologous Protein Engineering and characterization of native...
      Date: October 14, 2021 Time: 7:00am (PDT), 10:00am (EDT) Heterologous protein expression in model organisms has many applications, including protein engineering, production of industrial enz...
      Speaker: Tyson Shepherd, PhD
      Sponsored By: Inscripta
      22
      AUG 25, 2021 | 8:00 AM
      Improving heterologous protein production in yeast with massively parallel CRISPR genome editing
      Improving heterologous protein production in yeast with massively...
      Date: August 25, 2021 Time: 8:00am (PDT), 11:00am (EDT) Heterologous protein production is an indispensable tool in biotechnology and biopharma for manufacturing enzymes, protein therapeutic...
      Speaker: Eric Abbate
      Sponsored By: Inscripta
      5 2
      FEB 24, 2021 | 10:00 AM
      Biosafety Enclosures and the Automated Lab: Steps for Success
      Biosafety Enclosures and the Automated Lab: Steps for Success
      DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
      Speaker: David Wasescha , Simon Fogarty
      Sponsored By: Labconco
      15
      JAN 26, 2021 | 8:00 AM
      High-throughput CRISPR editing using the Onyxâ„¢ platform identifies essential residues in proteins
      High-throughput CRISPR editing using the Onyxâ„¢ platform identifies...
      Date: January 26, 2021 Time: 9:00am (PST), 12:00pm (EST) Over the past years, CRISPR/Cas genome editing has quickly become the method of choice for genetic manipulation, owing to its ease-of...
      Speaker: Liselot Dewachter, PhD , Laura Klitten, Ph.D.
      Sponsored By: Inscripta
      13 2
      NOV 12, 2020 | 12:00 AM
      Principles of Effective Method Development in Pathobiology Research
      Principles of Effective Method Development in Pathobiology Research
      Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
      Speaker: Vivian Barry, MS
      Presented at: DISCOVERY Global User Symposium
      2
      OCT 08, 2020 | 6:00 PM
      Multimodal analysis of circulating cell-free RNA (ccfRNA), cell-free DNA (ccfDNA), genomic DNA (gDNA) and CTCs from blood samples in cancer research
      Multimodal analysis of circulating cell-free RNA (ccfRNA), cell-free...
      While circulating cell-free DNA (ccfDNA) and to some extend CTCs from blood are routinely used as analyte in liquid biopsy cancer research applications, circulating cell-free RNA (ccfRNA) ha...
      Speaker: Thorsten Voss, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      4
      OCT 08, 2020 | 6:00 PM
      High-throughput biomarker profiling in immuno-oncology research & development
      High-throughput biomarker profiling in immuno-oncology research...
      Soluble cytokine biomarkers are the master regulators of cell-to-cell communication-- the means by which one cell tells another what to do or where to go. Determining the biomarker signature...
      Speaker: Jenny Koenitzer, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      3
      OCT 08, 2020 | 4:30 PM
      Multiplex detection of oncogenic mutations using LNA-based assays on the QIAcuity digital PCR system
      Multiplex detection of oncogenic mutations using LNA-based assays...
      Multiplex detection of oncogenic mutations using LNA-based assays on the QIAcuity digital PCR system Digital PCR (dPCR) enables specific and sensitive detection of genetic alterations in onc...
      Speaker: Dr. Özlem Karalay
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      2
      OCT 08, 2020 | 3:00 PM
      Reducing biological variance in tumor-antigen expression to standardize potency testing for immunotherapies
      Reducing biological variance in tumor-antigen expression to standardize...
      The continued rapid expansion of immunotherapies, including both in vivo and ex vivo therapeutics, has driven the development and adoption of novel tools to study, asses and understand these...
      Speaker: Benjamin Borgo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      1
      OCT 08, 2020 | 1:30 PM
      Nucleic acid preparation - DNA, RNA and retrieving both from the same FFPE sample
      Nucleic acid preparation - DNA, RNA and retrieving both from the...
      Martin highlights various factors impacting molecular analysis from FFPE samples and key challenges and considerations while working with this precious yet challenging sample type. Learning...
      Speaker: Martin Schlumpberger, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      2
      OCT 08, 2020 | 12:00 PM
      ZooMAb® Antibodies- a Novel Recombinant Antibody Technology
      ZooMAb® Antibodies- a Novel Recombinant Antibody Technology
      Antibodies have become one of the most important tools in life science research, allowing the detection, quantitation, and determination of changes in proteins and other molecules with respe...
      Speaker: Wayne Speckmann, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2
      OCT 08, 2020 | 10:30 AM
      Keynote Presentation: Principles of Effective Method Development in Pathobiology Research.
      Keynote Presentation: Principles of Effective Method Development...
      Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
      Speaker: Vivian Barry, MS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: Roche Diagnostics
      1
      OCT 08, 2020 | 9:00 AM
      Blood-based detection of EGFR and KRAS mutations for NSCLC patients using multiplexed droplet digital PCR
      Blood-based detection of EGFR and KRAS mutations for NSCLC patients...
      Mutations in the epidermal growth factor receptor gene (EGFR) and the known Kirsten rat sarcoma viral oncogene (KRAS) are significant drivers in the development of non-small-cell lung cancer...
      Speaker: Hestia Mellert, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: Bio-Rad Laboratories
      2
      OCT 08, 2020 | 7:30 AM
      Keynote Presentation: RNA Splicing and Ancestry-related Molecular Targets in Precision Oncology and Cancer Disparities
      Keynote Presentation: RNA Splicing and Ancestry-related Molecular...
      Individuals of under-represented minority ancestry are at disproportional risk for higher incidence and mortality rates for particular cancers. The unequal burden of cancer in certain racial...
      Speaker: Steven R. Patierno, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      4
      OCT 08, 2020 | 6:00 AM
      Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
      Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
      Every patient is different and so is every tumor! The term “personalized oncology” today is largely associated with sequencing approaches. Current publications proof more and mor...
      Speaker: Christian Regenbrecht, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: Luminex - A DiaSorin Company
      1
      OCT 08, 2020 | 12:00 AM
      Getting Under the Hood of Racial Disparities in Prostate Cancer
      Getting Under the Hood of Racial Disparities in Prostate Cancer
      Learning Objectives: 1. Understand the evolving epidemiology of prostate cancer in the the US and globally, and the excess burden of disease borne by men of African ancestry 2. Describe the...
      Speaker: Matthew R. Cooperberg, MD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      1
      OCT 08, 2020 | 12:00 AM
      The biology of cancer disparities: an innate immunity story
      The biology of cancer disparities: an innate immunity story
      Cancer disparities among persons of African descent are driven by both biological and nonbiological factors. There is evidence in breast cancer that psychosocial factors (environment, socioe...
      Speaker: K. Sean Kimbro, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      1
      OCT 08, 2020 | 12:00 AM
      We Don't Care What You Know Until You Show Us That You Care': Characterizing Access to Healthcare among Black, Hispanic and White Cancer Survivors
      We Don't Care What You Know Until You Show Us That You Care':...
      Background: Healthcare access (HCA) encompasses five important dimensions: Affordability, Availability, Accessibility, Accommodation and Acceptability. Published studies of cancer typically...
      Speaker: Tomi Akinyemiju, PhD, MS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      2
      OCT 08, 2020 | 12:00 AM
      Hereditary Cancer Genetics
      Hereditary Cancer Genetics
      Learning Objectives: 1. To provide an overview of relevant hereditary cancer syndromes 2. To encourage providers to obtain a thorough family history 3. To educate providers about available r...
      Speaker: Rinki Agarwal, MD FACOG,FACMG
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      4
      OCT 08, 2020 | 12:00 AM
      Transcriptome analysis of breast cancer clinical specimens with long-read sequencer
      Transcriptome analysis of breast cancer clinical specimens with...
      Changes in transcriptional regulation are thought to be one of the key drivers of carcinogenesis. Although next-generation sequencer revolutionized transcriptome analysis, there are limitati...
      Speaker: Masahito Kawazu, MD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      1
      OCT 07, 2020 | 1:30 PM
      Artificial Intelligence in Digital Pathology
      Artificial Intelligence in Digital Pathology
      Join Branden Hopkinson, Product Marketing Manager at Visiopharm, who will talk about using AI classifiers to find patterns in your images and which artificial intelligence method will work b...
      Speaker: Branden Hopkinson, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: Visiopharm®
      3
      OCT 07, 2020 | 12:00 PM
      Drugging the Undruggable Cancer Targets
      Drugging the Undruggable Cancer Targets
      Cancer is a multifactorial disease, and its genesis and progression are extremely complex. The scope of precision oncology is rapidly expanding to address previously undruggable targets. The...
      Speaker: Dr. Ming Liu
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: ChemPartner
      1
    NOV 01, 2022 | 10:00 AM
    Flow cytometric gene mutation assay, made possible by immunomagnetic separation, achieves OECD regulatory status
    Flow cytometric gene mutation assay, made possible by immunomagnetic...
    Date: November 01, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 6:00pm (CET) Our laboratory developed the Pig-a gene mutation assay as a means to simply and reliably evaluate the potential mutage...
    Speaker: Jeffrey Bemis, Ph.D. , Joe Ostrand, Ph.D.
    Sponsored By: Miltenyi Biotec
    11
    MAY 26, 2022 | 8:00 AM
    Cell-Free Tools to Revolutionize the DNA Construction Paradigm
    Cell-Free Tools to Revolutionize the DNA Construction Paradigm
    Date: May 26, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST), 12:00am JST The industry still relies heavily on PCR and cell-based cloning. Both are decades old methodologies. However,...
    Speaker: Shige Sasaki , Kazu Isono
    Sponsored By: OriCiro Genomics
    6
    OCT 14, 2021 | 7:00 AM
    Heterologous Protein Engineering and characterization of native regulatory elements  in E. coli using Massively Parallel CRISPR Editing
    Heterologous Protein Engineering and characterization of native...
    Date: October 14, 2021 Time: 7:00am (PDT), 10:00am (EDT) Heterologous protein expression in model organisms has many applications, including protein engineering, production of industrial enz...
    Speaker: Tyson Shepherd, PhD
    Sponsored By: Inscripta
    22
    AUG 25, 2021 | 8:00 AM
    Improving heterologous protein production in yeast with massively parallel CRISPR genome editing
    Improving heterologous protein production in yeast with massively...
    Date: August 25, 2021 Time: 8:00am (PDT), 11:00am (EDT) Heterologous protein production is an indispensable tool in biotechnology and biopharma for manufacturing enzymes, protein therapeutic...
    Speaker: Eric Abbate
    Sponsored By: Inscripta
    5 2
    FEB 24, 2021 | 10:00 AM
    Biosafety Enclosures and the Automated Lab: Steps for Success
    Biosafety Enclosures and the Automated Lab: Steps for Success
    DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
    Speaker: David Wasescha , Simon Fogarty
    Sponsored By: Labconco
    15
     
     
  • JAN 26, 2021 | 8:00 AM
    High-throughput CRISPR editing using the Onyxâ„¢ platform identifies essential residues in proteins
    High-throughput CRISPR editing using the Onyxâ„¢ platform identifies...
    Date: January 26, 2021 Time: 9:00am (PST), 12:00pm (EST) Over the past years, CRISPR/Cas genome editing has quickly become the method of choice for genetic manipulation, owing to its ease-of...
    Speaker: Liselot Dewachter, PhD , Laura Klitten, Ph.D.
    Sponsored By: Inscripta
    13 2
    NOV 12, 2020 | 12:00 AM
    Principles of Effective Method Development in Pathobiology Research
    Principles of Effective Method Development in Pathobiology Research
    Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
    Speaker: Vivian Barry, MS
    Presented at: DISCOVERY Global User Symposium
    2
    OCT 08, 2020 | 6:00 PM
    Multimodal analysis of circulating cell-free RNA (ccfRNA), cell-free DNA (ccfDNA), genomic DNA (gDNA) and CTCs from blood samples in cancer research
    Multimodal analysis of circulating cell-free RNA (ccfRNA), cell-free...
    While circulating cell-free DNA (ccfDNA) and to some extend CTCs from blood are routinely used as analyte in liquid biopsy cancer research applications, circulating cell-free RNA (ccfRNA) ha...
    Speaker: Thorsten Voss, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    4
    OCT 08, 2020 | 6:00 PM
    High-throughput biomarker profiling in immuno-oncology research & development
    High-throughput biomarker profiling in immuno-oncology research...
    Soluble cytokine biomarkers are the master regulators of cell-to-cell communication-- the means by which one cell tells another what to do or where to go. Determining the biomarker signature...
    Speaker: Jenny Koenitzer, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    3
    OCT 08, 2020 | 4:30 PM
    Multiplex detection of oncogenic mutations using LNA-based assays on the QIAcuity digital PCR system
    Multiplex detection of oncogenic mutations using LNA-based assays...
    Multiplex detection of oncogenic mutations using LNA-based assays on the QIAcuity digital PCR system Digital PCR (dPCR) enables specific and sensitive detection of genetic alterations in onc...
    Speaker: Dr. Özlem Karalay
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    2
     
     
  • OCT 08, 2020 | 3:00 PM
    Reducing biological variance in tumor-antigen expression to standardize potency testing for immunotherapies
    Reducing biological variance in tumor-antigen expression to standardize...
    The continued rapid expansion of immunotherapies, including both in vivo and ex vivo therapeutics, has driven the development and adoption of novel tools to study, asses and understand these...
    Speaker: Benjamin Borgo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    1
    OCT 08, 2020 | 1:30 PM
    Nucleic acid preparation - DNA, RNA and retrieving both from the same FFPE sample
    Nucleic acid preparation - DNA, RNA and retrieving both from the...
    Martin highlights various factors impacting molecular analysis from FFPE samples and key challenges and considerations while working with this precious yet challenging sample type. Learning...
    Speaker: Martin Schlumpberger, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    2
    OCT 08, 2020 | 12:00 PM
    ZooMAb® Antibodies- a Novel Recombinant Antibody Technology
    ZooMAb® Antibodies- a Novel Recombinant Antibody Technology
    Antibodies have become one of the most important tools in life science research, allowing the detection, quantitation, and determination of changes in proteins and other molecules with respe...
    Speaker: Wayne Speckmann, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2
    OCT 08, 2020 | 10:30 AM
    Keynote Presentation: Principles of Effective Method Development in Pathobiology Research.
    Keynote Presentation: Principles of Effective Method Development...
    Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
    Speaker: Vivian Barry, MS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: Roche Diagnostics
    1
    OCT 08, 2020 | 9:00 AM
    Blood-based detection of EGFR and KRAS mutations for NSCLC patients using multiplexed droplet digital PCR
    Blood-based detection of EGFR and KRAS mutations for NSCLC patients...
    Mutations in the epidermal growth factor receptor gene (EGFR) and the known Kirsten rat sarcoma viral oncogene (KRAS) are significant drivers in the development of non-small-cell lung cancer...
    Speaker: Hestia Mellert, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: Bio-Rad Laboratories
    2
     
     
  • OCT 08, 2020 | 7:30 AM
    Keynote Presentation: RNA Splicing and Ancestry-related Molecular Targets in Precision Oncology and Cancer Disparities
    Keynote Presentation: RNA Splicing and Ancestry-related Molecular...
    Individuals of under-represented minority ancestry are at disproportional risk for higher incidence and mortality rates for particular cancers. The unequal burden of cancer in certain racial...
    Speaker: Steven R. Patierno, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    4
    OCT 08, 2020 | 6:00 AM
    Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
    Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
    Every patient is different and so is every tumor! The term “personalized oncology” today is largely associated with sequencing approaches. Current publications proof more and mor...
    Speaker: Christian Regenbrecht, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: Luminex - A DiaSorin Company
    1
    OCT 08, 2020 | 12:00 AM
    Getting Under the Hood of Racial Disparities in Prostate Cancer
    Getting Under the Hood of Racial Disparities in Prostate Cancer
    Learning Objectives: 1. Understand the evolving epidemiology of prostate cancer in the the US and globally, and the excess burden of disease borne by men of African ancestry 2. Describe the...
    Speaker: Matthew R. Cooperberg, MD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    1
    OCT 08, 2020 | 12:00 AM
    The biology of cancer disparities: an innate immunity story
    The biology of cancer disparities: an innate immunity story
    Cancer disparities among persons of African descent are driven by both biological and nonbiological factors. There is evidence in breast cancer that psychosocial factors (environment, socioe...
    Speaker: K. Sean Kimbro, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    1
    OCT 08, 2020 | 12:00 AM
    We Don't Care What You Know Until You Show Us That You Care': Characterizing Access to Healthcare among Black, Hispanic and White Cancer Survivors
    We Don't Care What You Know Until You Show Us That You Care':...
    Background: Healthcare access (HCA) encompasses five important dimensions: Affordability, Availability, Accessibility, Accommodation and Acceptability. Published studies of cancer typically...
    Speaker: Tomi Akinyemiju, PhD, MS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    2
     
     
  • OCT 08, 2020 | 12:00 AM
    Hereditary Cancer Genetics
    Hereditary Cancer Genetics
    Learning Objectives: 1. To provide an overview of relevant hereditary cancer syndromes 2. To encourage providers to obtain a thorough family history 3. To educate providers about available r...
    Speaker: Rinki Agarwal, MD FACOG,FACMG
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    4
    OCT 08, 2020 | 12:00 AM
    Transcriptome analysis of breast cancer clinical specimens with long-read sequencer
    Transcriptome analysis of breast cancer clinical specimens with...
    Changes in transcriptional regulation are thought to be one of the key drivers of carcinogenesis. Although next-generation sequencer revolutionized transcriptome analysis, there are limitati...
    Speaker: Masahito Kawazu, MD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    1
    OCT 07, 2020 | 1:30 PM
    Artificial Intelligence in Digital Pathology
    Artificial Intelligence in Digital Pathology
    Join Branden Hopkinson, Product Marketing Manager at Visiopharm, who will talk about using AI classifiers to find patterns in your images and which artificial intelligence method will work b...
    Speaker: Branden Hopkinson, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: Visiopharm®
    3
    OCT 07, 2020 | 12:00 PM
    Drugging the Undruggable Cancer Targets
    Drugging the Undruggable Cancer Targets
    Cancer is a multifactorial disease, and its genesis and progression are extremely complex. The scope of precision oncology is rapidly expanding to address previously undruggable targets. The...
    Speaker: Dr. Ming Liu
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: ChemPartner
    1
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