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    Biomarker Discovery

    Biomarker Discovery is a process in which molecular substances in the body are used to indicate health or disease. One of the biggest challenges in biomarker discovery is the difficulty of identifying medium to low abundance proteins in complex biological samples.

    Webinars

    • SEP 30, 2020 | 9:00 AM
      Massively parallel microbial genome engineering using the Onyxâ„¢ Platform
      Massively parallel microbial genome engineering using the Onyxâ„¢...
      While transformative, first-generation CRISPR technologies remain limited across multiple important dimensions including scalability, editing efficiency, types of modifications available, an...
      Speaker: Nandini Krishnamurthy, PhD
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: Inscripta
      2
      SEP 30, 2020 | 7:30 AM
      Keynote Presentation: Functionalizing Genome Editing Techniques on a Broad Range of Cellular Targets
      Keynote Presentation: Functionalizing Genome Editing Techniques...
      Genome Engineering allows the easy manipulation of genomes down to the nucleotide level. Targeted deep sequencing enables the detection and quantification of low-frequency editing events. Ho...
      Speaker: Shondra Miller, PhD/Director
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 30, 2020 | 6:00 AM
      Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
      Enhancing efficiency and specificity with improved CRISPR components...
      Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
      Speaker: Ashley Jacobi
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: IDT
      2
      SEP 30, 2020 | 12:00 AM
      Applying targeted long-read sequencing to assess an expanded repeat in C9orf72
      Applying targeted long-read sequencing to assess an expanded repeat...
      A repeat expansion in the C9orf72-SMCR8 complex subunit (C9orf72) represents the most common genetic cause of two fatal neurodegenerative diseases: frontotemporal dementia (FTD) and amyotrop...
      Speaker: Marka van Blitterswijk, MD, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
      SEP 30, 2020 | 12:00 AM
      Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics
      Elucidation of remdesivir cytotoxicity pathways through genome-wide...
      The adenosine analogue remdesivir has emerged as a front-line antiviral treatment for SARS-CoV-2, with preliminary evidence that it reduces the duration and severity of illness. Prior clinic...
      Speaker: Minja Velimirovic, MSc, PhD Candidate
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 30, 2020 | 12:00 AM
      CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
      CRISPR/Cas9 as a tool to model and study cancer - insights and...
      Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
      Speaker: Grace R. Anderson, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
      SEP 30, 2020 | 12:00 AM
      In vivo delivery of Cas9 ribonucleoprotein and donor DNA with gold nanoparticles
      In vivo delivery of Cas9 ribonucleoprotein and donor DNA with...
      Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
      Speaker: Niren Murthy
      Presented at: CRISPR Virtual Event Series 2020
      4
      SEP 30, 2020 | 12:00 AM
      An Automated Integrated Multiple Assay Platform utilizing CRISPR-based Transistors for CRISPR Quality Control Applications
      An Automated Integrated Multiple Assay Platform utilizing CRISPR-based...
      Learning Objectives: 1. Using an optics- and label-free approach to CRISPR research 2. Explain current approaches to selecting the most robust gRNA for CRISPR assays 3. The opportunities tha...
      Speaker: Kiana Aran, PhD
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 30, 2020 | 12:00 AM
      Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
      Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
      An extensively debated concern about CRISPR-Cas9 genome editing is that unspecific guide RNA (gRNA) binding may induce off-target mutations. However, accurate prediction of CRISPR-Cas9 off-t...
      Speaker: Adam Ameur
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 28, 2020 | 5:00 PM
      Applying a single-cell GPS to discover novel spatial biomarkers in FFPE tissues
      Applying a single-cell GPS to discover novel spatial biomarkers...
      Date: September 28, 2020 Time: 5:00pm (PDT), 8:00am (HKT), 9:00am (JST) Although there have been dramatic advances in the field of single-cell sequencing, current methods cannot be applied t...
      Speaker: Kohta Miyawaki, MD, PhD , Aaron Mayer, PhD , Oliver Braubach, Ph.D.
      Sponsored By: Akoya Biosciences
      12
      SEP 23, 2020 | 11:30 AM
      Break-out: Setting Yourself Up for Core Success - A panel discussion
      Break-out: Setting Yourself Up for Core Success - A panel discussion
      Suspension by day, imaging by night: how to efficiently manage your system and optimize utilization Presented By: Jared K. Burks, PhD Mass cytometry, be it suspension or imaging, opens the d...
      Speaker: Jared K. Burks, PhD , Matthew Cochran, MS , Emily Thrash, PhD , Akil Merchant, MD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      1
      SEP 17, 2020 | 3:30 PM
      SARS-CoV-2 Testing Today and a New Serology Approach For High Throughput Screening
      SARS-CoV-2 Testing Today and a New Serology Approach For High...
      Richard Hughes: New immunogenicity strategies to meet the needs of a developing pandemic Shortly after the COVID-19 pandemic began, the subject of serological testing for anti-viral antibodi...
      Speaker: Russell Garlick, PhD , Richard Hughes , Joel Lefferts, PhD, HCLD, DABCC
      Presented at: Coronavirus Series
      Sponsored By: LGC Seracare
      1
      SEP 16, 2020 | 9:00 AM
      Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
      Deep multi-omic phenotyping of biospecimens for immuno-oncology...
      Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
      Speaker: Dr. Shawn Fahl
      Sponsored By: Miltenyi Biotec
      11
      SEP 15, 2020 | 8:00 AM
      Next generation ultra high content analysis of the tumor immune microenvironment using MICS technology
      Next generation ultra high content analysis of the tumor immune...
      DATE: September 15, 2020 TIME: 08:00am PT Tumorigenesis and cancer progression are affected by the tumor immune microenvironment (TIME). The TIME not only influences the efficiency of existi...
      Speaker: Stefan Eulitz
      Sponsored By: Miltenyi Biotec
      15 2
      SEP 04, 2020 | 8:00 AM
      Incorporation and Automation of RNAscope Technology into your COVID-19 Viral Pathogenesis Research
      Incorporation and Automation of RNAscope Technology into your...
      Date: September 4, 2020 Time: 8:00am (PTD), 11:00am (ETD) Direct detection of viral RNA in human or other animal cells by RNA in situ hybridization (ISH) is a powerful tool to establish the...
      Speaker: Jyoti Phatak-Sheldon , Andrea De Biase, M.S. , Damian Cockfield
      Sponsored By: Leica Biosystems, ACD - A Bio-Techne Brand
      14 8
      SEP 03, 2020 | 9:00 AM
      The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
      The Complexities of SV Analytical Ultracentrifugation: AAVs are...
      DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
      Speaker: Dr. Lake Paul
      Sponsored By: Beckman Coulter Life Sciences
      12
      AUG 06, 2020 | 10:00 AM
      Single Cell Antibody Discovery Using 'Islands of Automation'
      Single Cell Antibody Discovery Using 'Islands of Automation'
      DATE: August 6th, 2020 TIME: 10:00am PT In recent years Lilly has implemented a Next Generation Research (NGR) initiative to improve the value output of the R&D portfolio. One of the NGR...
      Speaker: Paul Anderson
      Sponsored By: Beckman Coulter Life Sciences
      16 5
      JUL 23, 2020 | 10:00 AM
      Understanding the potential impact of the gut microbiome on SARS-CoV-2 Research
      Understanding the potential impact of the gut microbiome on SARS-CoV-2...
      DATE: July 23, 2020 TIME: 10:00am PDT, 1:00pm EDT SARS-CoV-2 virus has impacted billions of lives globally and has spurred many scientists to address some of the biggest questions regarding...
      Speaker: Heesun Shin
      Sponsored By: Thermo Fisher Scientific
      44 8
      JUL 07, 2020 | 9:30 AM
      Evaluating tumor-immune cell interactions in human lung cancer using multiparametric and spatially resolved tissue analysis
      Evaluating tumor-immune cell interactions in human lung cancer...
      ...
      Speaker: Kurt Schalper, MD, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      1
      JUL 07, 2020 | 8:00 AM
      Development of an extraction-free, saliva-based workflow for SARS-CoV-2 detection with the Biomarkâ„¢ HD platform
      Development of an extraction-free, saliva-based workflow for SARS-CoV-2...
      The need for high-throughput laboratory testing to identify SARS-CoV-2 infected individuals has reached nearly unprecedented levels. This demand has also led to supply chain issues that have...
      Speaker: David King, PhD , Richard Head, MS
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      1
      JUL 02, 2020 | 12:45 PM
      Strategies to normalize miRNA expression in serum and plasma
      Strategies to normalize miRNA expression in serum and plasma
      MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post transcriptional level. They are known to play a critical role in multiple biologi...
      Speaker: Emily Zeringer , Harita Veereshlingam, PhD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      2
      JUN 17, 2020 | 1:30 PM
      Will we have a vaccine for COVID-19? 5 reasons for optimism!
      Will we have a vaccine for COVID-19? 5 reasons for optimism!
      The COVID-19 pandemic has resulted in over 7 million cases and more than 428000 cases to date. While public health interventions and social distancing measures have been effective in slowing...
      Speaker: Rob Kozak, PhD FCCM
      Presented at: Coronavirus Series
      1
      JUN 17, 2020 | 7:30 AM
      Development of Luminex Based Serological Test for COVID-19 Diagnosis and Monitoring
      Development of Luminex Based Serological Test for COVID-19 Diagnosis...
      Coronavirus disease 2019 (Covid-19) is a global pandemic that has impacted the lives of the entire world’s population. Accurate and effective testing mechanisms to identify those with...
      Speaker: Imad Tarhoni, MD, PhD
      Presented at: Coronavirus Series
      Sponsored By: Luminex - A DiaSorin Company
      2
      JUN 03, 2020 | 7:00 AM
      High throughput biomarker profiling for immuno-oncology research using MILLIPLEX® assays
      High throughput biomarker profiling for immuno-oncology research...
      Dr. Koenitzer will present an overview of her current research in immune suppression. After a brief introduction to the MILLIPLEX® multiplex immunoassay portfolio, Dr. Koenitzer will dis...
      Speaker: Jenny Koenitzer, PhD , Yan Nikhamin, MS, MBA
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      1
    SEP 30, 2020 | 9:00 AM
    Massively parallel microbial genome engineering using the Onyxâ„¢ Platform
    Massively parallel microbial genome engineering using the Onyxâ„¢...
    While transformative, first-generation CRISPR technologies remain limited across multiple important dimensions including scalability, editing efficiency, types of modifications available, an...
    Speaker: Nandini Krishnamurthy, PhD
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: Inscripta
    2
    SEP 30, 2020 | 7:30 AM
    Keynote Presentation: Functionalizing Genome Editing Techniques on a Broad Range of Cellular Targets
    Keynote Presentation: Functionalizing Genome Editing Techniques...
    Genome Engineering allows the easy manipulation of genomes down to the nucleotide level. Targeted deep sequencing enables the detection and quantification of low-frequency editing events. Ho...
    Speaker: Shondra Miller, PhD/Director
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 30, 2020 | 6:00 AM
    Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
    Enhancing efficiency and specificity with improved CRISPR components...
    Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
    Speaker: Ashley Jacobi
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: IDT
    2
    SEP 30, 2020 | 12:00 AM
    Applying targeted long-read sequencing to assess an expanded repeat in C9orf72
    Applying targeted long-read sequencing to assess an expanded repeat...
    A repeat expansion in the C9orf72-SMCR8 complex subunit (C9orf72) represents the most common genetic cause of two fatal neurodegenerative diseases: frontotemporal dementia (FTD) and amyotrop...
    Speaker: Marka van Blitterswijk, MD, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
    SEP 30, 2020 | 12:00 AM
    Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics
    Elucidation of remdesivir cytotoxicity pathways through genome-wide...
    The adenosine analogue remdesivir has emerged as a front-line antiviral treatment for SARS-CoV-2, with preliminary evidence that it reduces the duration and severity of illness. Prior clinic...
    Speaker: Minja Velimirovic, MSc, PhD Candidate
    Presented at: CRISPR Virtual Event Series 2020
    1
     
     
  • SEP 30, 2020 | 12:00 AM
    CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
    CRISPR/Cas9 as a tool to model and study cancer - insights and...
    Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
    Speaker: Grace R. Anderson, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
    SEP 30, 2020 | 12:00 AM
    In vivo delivery of Cas9 ribonucleoprotein and donor DNA with gold nanoparticles
    In vivo delivery of Cas9 ribonucleoprotein and donor DNA with...
    Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
    Speaker: Niren Murthy
    Presented at: CRISPR Virtual Event Series 2020
    4
    SEP 30, 2020 | 12:00 AM
    An Automated Integrated Multiple Assay Platform utilizing CRISPR-based Transistors for CRISPR Quality Control Applications
    An Automated Integrated Multiple Assay Platform utilizing CRISPR-based...
    Learning Objectives: 1. Using an optics- and label-free approach to CRISPR research 2. Explain current approaches to selecting the most robust gRNA for CRISPR assays 3. The opportunities tha...
    Speaker: Kiana Aran, PhD
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 30, 2020 | 12:00 AM
    Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
    Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
    An extensively debated concern about CRISPR-Cas9 genome editing is that unspecific guide RNA (gRNA) binding may induce off-target mutations. However, accurate prediction of CRISPR-Cas9 off-t...
    Speaker: Adam Ameur
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 28, 2020 | 5:00 PM
    Applying a single-cell GPS to discover novel spatial biomarkers in FFPE tissues
    Applying a single-cell GPS to discover novel spatial biomarkers...
    Date: September 28, 2020 Time: 5:00pm (PDT), 8:00am (HKT), 9:00am (JST) Although there have been dramatic advances in the field of single-cell sequencing, current methods cannot be applied t...
    Speaker: Kohta Miyawaki, MD, PhD , Aaron Mayer, PhD , Oliver Braubach, Ph.D.
    Sponsored By: Akoya Biosciences
    12
     
     
  • SEP 23, 2020 | 11:30 AM
    Break-out: Setting Yourself Up for Core Success - A panel discussion
    Break-out: Setting Yourself Up for Core Success - A panel discussion
    Suspension by day, imaging by night: how to efficiently manage your system and optimize utilization Presented By: Jared K. Burks, PhD Mass cytometry, be it suspension or imaging, opens the d...
    Speaker: Jared K. Burks, PhD , Matthew Cochran, MS , Emily Thrash, PhD , Akil Merchant, MD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    1
    SEP 17, 2020 | 3:30 PM
    SARS-CoV-2 Testing Today and a New Serology Approach For High Throughput Screening
    SARS-CoV-2 Testing Today and a New Serology Approach For High...
    Richard Hughes: New immunogenicity strategies to meet the needs of a developing pandemic Shortly after the COVID-19 pandemic began, the subject of serological testing for anti-viral antibodi...
    Speaker: Russell Garlick, PhD , Richard Hughes , Joel Lefferts, PhD, HCLD, DABCC
    Presented at: Coronavirus Series
    Sponsored By: LGC Seracare
    1
    SEP 16, 2020 | 9:00 AM
    Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
    Deep multi-omic phenotyping of biospecimens for immuno-oncology...
    Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
    Speaker: Dr. Shawn Fahl
    Sponsored By: Miltenyi Biotec
    11
    SEP 15, 2020 | 8:00 AM
    Next generation ultra high content analysis of the tumor immune microenvironment using MICS technology
    Next generation ultra high content analysis of the tumor immune...
    DATE: September 15, 2020 TIME: 08:00am PT Tumorigenesis and cancer progression are affected by the tumor immune microenvironment (TIME). The TIME not only influences the efficiency of existi...
    Speaker: Stefan Eulitz
    Sponsored By: Miltenyi Biotec
    15 2
    SEP 04, 2020 | 8:00 AM
    Incorporation and Automation of RNAscope Technology into your COVID-19 Viral Pathogenesis Research
    Incorporation and Automation of RNAscope Technology into your...
    Date: September 4, 2020 Time: 8:00am (PTD), 11:00am (ETD) Direct detection of viral RNA in human or other animal cells by RNA in situ hybridization (ISH) is a powerful tool to establish the...
    Speaker: Jyoti Phatak-Sheldon , Andrea De Biase, M.S. , Damian Cockfield
    Sponsored By: Leica Biosystems, ACD - A Bio-Techne Brand
    14 8
     
     
  • SEP 03, 2020 | 9:00 AM
    The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
    The Complexities of SV Analytical Ultracentrifugation: AAVs are...
    DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
    Speaker: Dr. Lake Paul
    Sponsored By: Beckman Coulter Life Sciences
    12
    AUG 06, 2020 | 10:00 AM
    Single Cell Antibody Discovery Using 'Islands of Automation'
    Single Cell Antibody Discovery Using 'Islands of Automation'
    DATE: August 6th, 2020 TIME: 10:00am PT In recent years Lilly has implemented a Next Generation Research (NGR) initiative to improve the value output of the R&D portfolio. One of the NGR...
    Speaker: Paul Anderson
    Sponsored By: Beckman Coulter Life Sciences
    16 5
    JUL 23, 2020 | 10:00 AM
    Understanding the potential impact of the gut microbiome on SARS-CoV-2 Research
    Understanding the potential impact of the gut microbiome on SARS-CoV-2...
    DATE: July 23, 2020 TIME: 10:00am PDT, 1:00pm EDT SARS-CoV-2 virus has impacted billions of lives globally and has spurred many scientists to address some of the biggest questions regarding...
    Speaker: Heesun Shin
    Sponsored By: Thermo Fisher Scientific
    44 8
    JUL 07, 2020 | 9:30 AM
    Evaluating tumor-immune cell interactions in human lung cancer using multiparametric and spatially resolved tissue analysis
    Evaluating tumor-immune cell interactions in human lung cancer...
    ...
    Speaker: Kurt Schalper, MD, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    1
    JUL 07, 2020 | 8:00 AM
    Development of an extraction-free, saliva-based workflow for SARS-CoV-2 detection with the Biomarkâ„¢ HD platform
    Development of an extraction-free, saliva-based workflow for SARS-CoV-2...
    The need for high-throughput laboratory testing to identify SARS-CoV-2 infected individuals has reached nearly unprecedented levels. This demand has also led to supply chain issues that have...
    Speaker: David King, PhD , Richard Head, MS
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    1
     
     
  • JUL 02, 2020 | 12:45 PM
    Strategies to normalize miRNA expression in serum and plasma
    Strategies to normalize miRNA expression in serum and plasma
    MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post transcriptional level. They are known to play a critical role in multiple biologi...
    Speaker: Emily Zeringer , Harita Veereshlingam, PhD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    2
    JUN 17, 2020 | 1:30 PM
    Will we have a vaccine for COVID-19? 5 reasons for optimism!
    Will we have a vaccine for COVID-19? 5 reasons for optimism!
    The COVID-19 pandemic has resulted in over 7 million cases and more than 428000 cases to date. While public health interventions and social distancing measures have been effective in slowing...
    Speaker: Rob Kozak, PhD FCCM
    Presented at: Coronavirus Series
    1
    JUN 17, 2020 | 7:30 AM
    Development of Luminex Based Serological Test for COVID-19 Diagnosis and Monitoring
    Development of Luminex Based Serological Test for COVID-19 Diagnosis...
    Coronavirus disease 2019 (Covid-19) is a global pandemic that has impacted the lives of the entire world’s population. Accurate and effective testing mechanisms to identify those with...
    Speaker: Imad Tarhoni, MD, PhD
    Presented at: Coronavirus Series
    Sponsored By: Luminex - A DiaSorin Company
    2
    JUN 03, 2020 | 7:00 AM
    High throughput biomarker profiling for immuno-oncology research using MILLIPLEX® assays
    High throughput biomarker profiling for immuno-oncology research...
    Dr. Koenitzer will present an overview of her current research in immune suppression. After a brief introduction to the MILLIPLEX® multiplex immunoassay portfolio, Dr. Koenitzer will dis...
    Speaker: Jenny Koenitzer, PhD , Yan Nikhamin, MS, MBA
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    1
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