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    Brain Simulation

    Brain Simulation is a computer rendering of the brain involving the replication of neuron electrical and chemical attributes. The neural connectome, a complex wiring, of the target organism is an essential component to the model. The purpose of brain simulation projects are to create a better understanding of the brain and help the diagnosis and treatment of brain diseases.

    Webinars

    • JUL 26, 2023 | 2:30 PM
      Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
      Serine-129 phosphorylation of α-synuclein is an activity-dependent...
      Phosphorylation of α-synuclein at the Serine-129 site (α-syn Ser129P) is an established pathologic hallmark of synucleinopathies and a therapeutic target. In physiologic states,...
      Speaker: Dr. Leonardo Parra-Rivas
      Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
      4
      AUG 25, 2021 | 12:00 AM
      Can Multiscale Computer Modeling Save the Human Genome Project?: Climbing the Omes for Schizophrenia
      Can Multiscale Computer Modeling Save the Human Genome Project?:...
      Multiscale modeling has arisen as a focus of computational systems biology, with the realization that genome, proteome, connectome, etceteromes, will only become comprehensible once placed i...
      Speaker: William Lytton, MD
      Presented at: Neuroscience Virtual Event Series 2021
      3
      AUG 25, 2021 | 12:00 AM
      Rational Thoughts in Neural Codes
      Rational Thoughts in Neural Codes
      Complex behaviors are often driven by an internal model, which integrates sensory information over time and facilitates long-term planning to reach subjective goals. {\color{rev}A fundamenta...
      Speaker: Xaq Pitkow, Ph.D.
      Presented at: Neuroscience Virtual Event Series 2021
      1
      MAR 11, 2020 | 12:00 PM
      PANEL: Cracking a Neural Circuit's Function Through High-Resolution Physiology, Connectomics, and Computational Modeling
      PANEL: Cracking a Neural Circuit's Function Through High-Resolution...
      Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
      Speaker: Emre Aksay, PhD , Mark Goldman, PhD , Sebastian Seung, PhD , Ashwin Vishwanathan, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1 1
      MAR 11, 2020 | 9:00 AM
      Keynote Presentation: The BRAIN Initiative and its Promise for the Treatment of Neuro/Mental/Substance Abuse Disorders
      Keynote Presentation: The BRAIN Initiative and its Promise for...
      The US Brain Research through Advancing Innovative Neurotechnologies is a research program focused on building fundamental knowledge of how brain circuits process information to enable human...
      Speaker: Walter Koroshetz, MD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 9:00 AM
      PANEL: Neural circuit mechanisms of memory replay
      PANEL: Neural circuit mechanisms of memory replay
      Although neuroscience has provided a great deal of information about how neurons work, the fundamental question of how neurons function together in a network to produce cognition has been di...
      Speaker: György Buzsáki, PhD , Attila Losonczy , Mark Schnitzer , Ivan Soltesz
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 6:00 AM
      PANEL: Sensorimotor Processing, Decision Making, and Internal States: Towards a Realistic Multiscale Circuit Model of the Larval Zebrafish Brain
      PANEL: Sensorimotor Processing, Decision Making, and Internal...
      We present here a framework to generate a realistic multiscale circuit model of the larval zebrafish brain – the multiscale virtual fish (MVF). The model will be based on algorithms in...
      Speaker: Florian Engert, PhD , Jeff Lichtman, MD, PhD , Haim Sompolinsky
      Presented at: Neuroscience Virtual Event Series 2020
      1
      SEP 27, 2019 | 9:00 AM
      Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
      Investigating how Tpz-1 may be used as a novel therapeutic agent...
      DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
      Speaker: Jessica Hess
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
      AUG 15, 2019 | 9:00 AM
      Understanding and ameliorating radiation-induced damage to oligodendrocytes
      Understanding and ameliorating radiation-induced damage to oligodendrocytes
      DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
      Speaker: Alexandra Taraboletti, PHD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      JUL 31, 2019 | 9:00 AM
      Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
      Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
      DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
      Speaker: Elizabeth Delery, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7 1
      AUG 21, 2014 | 9:45 AM
      Pathway based analyses for genetic susceptibility to cancer and autoimmune disease
      Pathway based analyses for genetic susceptibility to cancer and...
      In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
      Speaker: Christopher I Amos, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      62
      MAR 20, 2014 | 10:00 AM
      Neuroeconomy; Economic Impact of Neurodegenerative Diseases both in the US and Globally
      Neuroeconomy; Economic Impact of Neurodegenerative Diseases both...
      When speaking of neurodegenerative diseases, average public is not made aware of the true cost that brain related disorders have on annual budget. The true impact on economy is not usually...
      Speaker: Lana Morrow, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      48
      MAR 19, 2014 | 9:00 AM
      Brain Computer Interfaces: Neurotech in the Future of Neuroscience
      Brain Computer Interfaces: Neurotech in the Future of Neuroscience
      When speaking of neurodegenerative diseases, average public is not made aware of the true cost that brain related disorders have on annual budget. The true impact on economy is not usually...
      Speaker: Lana Morrow, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      0
      AUG 21, 2013 | 8:00 AM
      Post Genome-Wide Association Studies
      Post Genome-Wide Association Studies
      In this presentation I describe some of the approaches we are taking to identify the genetic architecture of common complex cancers with a particular focus on the etiology of lung cancer. Can...
      Speaker: Christopher I Amos, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      105
    JUL 26, 2023 | 2:30 PM
    Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
    Serine-129 phosphorylation of α-synuclein is an activity-dependent...
    Phosphorylation of α-synuclein at the Serine-129 site (α-syn Ser129P) is an established pathologic hallmark of synucleinopathies and a therapeutic target. In physiologic states,...
    Speaker: Dr. Leonardo Parra-Rivas
    Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
    4
    AUG 25, 2021 | 12:00 AM
    Can Multiscale Computer Modeling Save the Human Genome Project?: Climbing the Omes for Schizophrenia
    Can Multiscale Computer Modeling Save the Human Genome Project?:...
    Multiscale modeling has arisen as a focus of computational systems biology, with the realization that genome, proteome, connectome, etceteromes, will only become comprehensible once placed i...
    Speaker: William Lytton, MD
    Presented at: Neuroscience Virtual Event Series 2021
    3
    AUG 25, 2021 | 12:00 AM
    Rational Thoughts in Neural Codes
    Rational Thoughts in Neural Codes
    Complex behaviors are often driven by an internal model, which integrates sensory information over time and facilitates long-term planning to reach subjective goals. {\color{rev}A fundamenta...
    Speaker: Xaq Pitkow, Ph.D.
    Presented at: Neuroscience Virtual Event Series 2021
    1
    MAR 11, 2020 | 12:00 PM
    PANEL: Cracking a Neural Circuit's Function Through High-Resolution Physiology, Connectomics, and Computational Modeling
    PANEL: Cracking a Neural Circuit's Function Through High-Resolution...
    Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
    Speaker: Emre Aksay, PhD , Mark Goldman, PhD , Sebastian Seung, PhD , Ashwin Vishwanathan, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1 1
    MAR 11, 2020 | 9:00 AM
    Keynote Presentation: The BRAIN Initiative and its Promise for the Treatment of Neuro/Mental/Substance Abuse Disorders
    Keynote Presentation: The BRAIN Initiative and its Promise for...
    The US Brain Research through Advancing Innovative Neurotechnologies is a research program focused on building fundamental knowledge of how brain circuits process information to enable human...
    Speaker: Walter Koroshetz, MD
    Presented at: Neuroscience Virtual Event Series 2020
    1
     
     
  • MAR 11, 2020 | 9:00 AM
    PANEL: Neural circuit mechanisms of memory replay
    PANEL: Neural circuit mechanisms of memory replay
    Although neuroscience has provided a great deal of information about how neurons work, the fundamental question of how neurons function together in a network to produce cognition has been di...
    Speaker: György Buzsáki, PhD , Attila Losonczy , Mark Schnitzer , Ivan Soltesz
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 11, 2020 | 6:00 AM
    PANEL: Sensorimotor Processing, Decision Making, and Internal States: Towards a Realistic Multiscale Circuit Model of the Larval Zebrafish Brain
    PANEL: Sensorimotor Processing, Decision Making, and Internal...
    We present here a framework to generate a realistic multiscale circuit model of the larval zebrafish brain – the multiscale virtual fish (MVF). The model will be based on algorithms in...
    Speaker: Florian Engert, PhD , Jeff Lichtman, MD, PhD , Haim Sompolinsky
    Presented at: Neuroscience Virtual Event Series 2020
    1
    SEP 27, 2019 | 9:00 AM
    Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
    Investigating how Tpz-1 may be used as a novel therapeutic agent...
    DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
    Speaker: Jessica Hess
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
    AUG 15, 2019 | 9:00 AM
    Understanding and ameliorating radiation-induced damage to oligodendrocytes
    Understanding and ameliorating radiation-induced damage to oligodendrocytes
    DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
    Speaker: Alexandra Taraboletti, PHD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    JUL 31, 2019 | 9:00 AM
    Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
    Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
    DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
    Speaker: Elizabeth Delery, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7 1
     
     
  • AUG 21, 2014 | 9:45 AM
    Pathway based analyses for genetic susceptibility to cancer and autoimmune disease
    Pathway based analyses for genetic susceptibility to cancer and...
    In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
    Speaker: Christopher I Amos, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    62
    MAR 20, 2014 | 10:00 AM
    Neuroeconomy; Economic Impact of Neurodegenerative Diseases both in the US and Globally
    Neuroeconomy; Economic Impact of Neurodegenerative Diseases both...
    When speaking of neurodegenerative diseases, average public is not made aware of the true cost that brain related disorders have on annual budget. The true impact on economy is not usually...
    Speaker: Lana Morrow, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    48
    MAR 19, 2014 | 9:00 AM
    Brain Computer Interfaces: Neurotech in the Future of Neuroscience
    Brain Computer Interfaces: Neurotech in the Future of Neuroscience
    When speaking of neurodegenerative diseases, average public is not made aware of the true cost that brain related disorders have on annual budget. The true impact on economy is not usually...
    Speaker: Lana Morrow, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    0
    AUG 21, 2013 | 8:00 AM
    Post Genome-Wide Association Studies
    Post Genome-Wide Association Studies
    In this presentation I describe some of the approaches we are taking to identify the genetic architecture of common complex cancers with a particular focus on the etiology of lung cancer. Can...
    Speaker: Christopher I Amos, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    105
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