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    Cancer Molecular Biology

    Molecular biology plays an important role in the diagnosis and treatment of cancer. On a biological level, the development of cancer is characterized by the acquisition of genetic mutations which cause abnormal cell growth, eventually resulting in malignant disease. Understanding how molecular damage can cause these cancer-driving mutations can help design optimal treatment regimens

    Webinars

    • JUN 20, 2019 | 6:00 AM
      Connecting Genetic and Transcriptional Variation in Acute Myeloid Leukemia at Single-Cell Resolution
      Connecting Genetic and Transcriptional Variation in Acute Myeloid...
      Virtually all tumors are genetically heterogeneous, containing subclonal populations of cells that are defined by distinct mutations. Subclones can have unique phenotypes that influence disea...
      Speaker: Stephen Williams, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      2
      JUN 20, 2019 | 6:00 AM
      Precise DNA Sequencing: A Necessity for Precision Medicine
      Precise DNA Sequencing: A Necessity for Precision Medicine
      It has been noted by many in the community that for Precision Medicine to become a transformative reality, the underlying DNA and RNA sequence data have to become more precise. In my talk, I...
      Speaker: Jonas Korlach, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      1
      JUN 19, 2019 | 10:00 AM
      Getting started in 3D:  Ask an Expert
      Getting started in 3D: Ask an Expert
      DATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...
      Speaker: Mark Kennedy, Ph.D. , Richard Josephson, PhD
      Sponsored By: Thermo Fisher Scientific
      6
      JUN 18, 2019 | 11:00 AM
      Writing the NIH Research (R01) grant: Strategies for Success
      Writing the NIH Research (R01) grant: Strategies for Success
      DATE: June 18, 2019TIME: 11:00am PDT, 2:00pm EDT With highly competitive NIH budgets and ever-increasing restrictions on federal spending, getting noticed and winning...
      Speaker: Christopher Dant, PhD
      Sponsored By: Leica Microsystems
      13
      JUN 05, 2019 | 5:00 PM
      Everyday culture practice - Improving reproducibility in cell culture
      Everyday culture practice - Improving reproducibility in cell...
      DATE: June 5, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal chan...
      Speaker: Jessica Wagener, PhD
      Sponsored By: Eppendorf
      23 2
      MAY 30, 2019 | 6:00 AM
      Improved Cancer Tracking Through Precision Quantification of Circulating Nucleic Acid Biomarkers
      Improved Cancer Tracking Through Precision Quantification of Circulating...
      Oncologists have many options when tasked with treating a patient’s cancer. Unfortunately, many cancer drugs and therapies come with potentially debilitating side effects. As such, it i...
      Speaker: Megan Dueck, PhD
      Presented at: Laboratory Testing & Automation Virtual Event Series 2019
      2
      MAY 21, 2019 | 7:00 AM
      Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
      Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key...
      DATE: May 21, 2019TIMEL 7:00am PT, 10:00am ET Human T cells are central effectors of immunity and cancer immunotherapy. CRISPR-based functional studies in T cells could prioriti...
      Speaker: Eric Shifrut, PhD
      Sponsored By: Thermo Fisher Scientific
      10 1
      MAY 16, 2019 | 4:00 PM
      Towards Standardized Workflows - A focus on microbiome insights
      Towards Standardized Workflows - A focus on microbiome insights
      DATE: May 16, 2019TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST The emergence of NGS is revolutionizing the microbiological sciences and transforming medicine. Deep sequencing has...
      Speaker: Rita Colwell, PhD , Christiane Honisch, PhD
      Sponsored By: Eppendorf
      10 2
      MAY 09, 2019 | 12:00 PM
      A Metagenomic Assay to Interrogate the Role of Virome and Microbiome in Cancer
      A Metagenomic Assay to Interrogate the Role of Virome and Microbiome...
      Screening to identify all known viruses and other pathogenic microorganisms including bacteria, fungus and parasites in human tumor tissues will provide a more comprehensive understanding of...
      Speaker: Erle Robertson, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: Agilent
      3
      MAY 09, 2019 | 10:30 AM
      Background and Troubleshooting for RT-PCR
      Background and Troubleshooting for RT-PCR
      Real-time PCR, or quantitative qPCR, is a commonly used molecular biology lab technique to determine the actual amount of PCR product at a given cycle. For quantitative reverse transcription...
      Speaker: Gillian Browne, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: MilliporeSigma
      4
      MAY 09, 2019 | 9:00 AM
      Polygenic Risk Scores: PheWas and GWAS and Utility of Biobank Information
      Polygenic Risk Scores: PheWas and GWAS and Utility of Biobank...
      The advent of precision medicine largely depends on the creation of precise and accurate predictive tools. While most late-onset diseases are moderately to highly heritable, using genetic inf...
      Speaker: Guillaume Paré, MD, MSc, FRCPC
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: Illumina
      2 1
      MAY 09, 2019 | 6:00 AM
      AI-Driven Literature Curation for Determining Genomic Variant Pathogenicity
      AI-Driven Literature Curation for Determining Genomic Variant...
      Variant interpretation presents a bottleneck for many labs, posing a challenge to the broader adoption of precision medicine. The ACMG/AMP variant classification framework has provided a foun...
      Speaker: Mark Kiel, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      4
      MAY 08, 2019 | 10:30 AM
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
      Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
      The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
      Speaker: Devendra Mistry, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      MAY 08, 2019 | 10:30 AM
      C.E. CREDITS
      Using Networks to Understand Cancer Risk
      Using Networks to Understand Cancer Risk
      One of the central tenants of biology is that our genetics—our genotype—influences the physical characteristics we manifest—our phenotype. But with more than 25,000 human ge...
      Speaker: John Quackenbush, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      MAY 08, 2019 | 6:00 AM
      C.E. CREDITS
      Novel DNA Methylation in Mammals
      Novel DNA Methylation in Mammals
      Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
      Speaker: Tao Wu, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      MAY 08, 2019 | 9:00 AM
      HPV-based cervical screening: from implementation to future possibilities
      HPV-based cervical screening: from implementation to future possibilities
      DATE: May 8, 2019TIME: 12:00am PDT In 2017 the first national cervical screening programs using human papillomavirus (HPV-based) primary screening were implemented. As these progr...
      Speaker: David Hawkes, PhD
      Sponsored By: Abbott Molecular Diagnostic
      8 2
      APR 25, 2019 | 6:00 AM
      Long-Read Sequencing and Infectious Disease: New Insights Into Longstanding Challenges
      Long-Read Sequencing and Infectious Disease: New Insights Into...
      To reduce the global burden diseases causes by infectious disease, including parasites and bacteria, scientists need better information about mechanisms of virulence, immune evasion, and drug...
      Speaker: Meredith Ashby, PhD
      Presented at: Infectious Disease Virtual Event Series 2019
      Sponsored By: PacBio
      2
      APR 18, 2019 | 9:00 AM
      Deep Learning in Optics
      Deep Learning in Optics
      DATE: April 18, 2019 TIME: 9:00am PDT...
      Speaker: Aydogan Ozcan, PhD , Hongda Wang, MS, BS , Yair Rivenson, PhD , Laurent Bentolila, PhD
      Sponsored By: Leica Microsystems
      4
      APR 10, 2019 | 1:30 PM
      Detection and Interpretation of Complex Myeloid Leukemia Mutations
      Detection and Interpretation of Complex Myeloid Leukemia Mutations
      Myeloid leukemias encompass a group of different diseases that include myeloproliferative neoplasms (MPN), myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). These diseases are d...
      Speaker: Véronique Laloux, PhD , Beate Litzenburger, Ph.D.
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      Sponsored By: QIAGEN
      6
      APR 10, 2019 | 1:30 PM
      Laboratory Medicine Beyond The Box: Value Based Health Care & Diagnostic Evidence
      Laboratory Medicine Beyond The Box: Value Based Health Care &...
      Integration of technology is influencing practice in the clinical laboratory and treatment of patients in the clinical practice arena. As laboratories begin to move from a volume to value mod...
      Speaker: Elizabeth Marlowe, PhD, D(ABMM) , Joanna Sickler, MPH, MBA
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      4
      APR 10, 2019 | 1:30 PM
      Tools & Processes for Making Evidence-Based Policy Decisions
      Tools & Processes for Making Evidence-Based Policy Decisions
      The exponential advents of advances in techniques and types of molecular diagnostic testing, and modifying strategies for these tests, are encouraging; but these evolutions simultaneously con...
      Speaker: Eugean Jiwanmall, MPH, MBA
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      3
      APR 10, 2019 | 12:00 PM
      Digital Biosensors and the Internet of Biology
      Digital Biosensors and the Internet of Biology
      The prevailing philosophy in biological testing has been to focus on simple tests with easy to interpret information such as ELISA or lateral flow assays. At the same time, there has been a d...
      Speaker: Brett Goldsmith, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      4
      APR 10, 2019 | 12:00 PM
      Best Practices for Implementing NGS and Positioning for Future Growth: Perspectives from 2 Labs
      Best Practices for Implementing NGS and Positioning for Future...
      Personalized medicine driven by genomic-based treatments continues to increase in importance. Representatives from two distinct healthcare entities – a regional reference lab and commun...
      Speaker: Tony Magliocco, MD , Keith Gligorich, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      Sponsored By: Illumina
      7
      APR 10, 2019 | 12:00 PM
      Transforming Oncology with ctDNA+ctRNA Liquid Biopsy Solutions
      Transforming Oncology with ctDNA+ctRNA Liquid Biopsy Solutions
      Determining which patients would derive clinical benefit from immunotherapy is a compelling clinical question. Biomarkers have been shown to predict therapy outcome in various types of cancer...
      Speaker: Shidong Jia, MD, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      4
    JUN 20, 2019 | 6:00 AM
    Connecting Genetic and Transcriptional Variation in Acute Myeloid Leukemia at Single-Cell Resolution
    Connecting Genetic and Transcriptional Variation in Acute Myeloid...
    Virtually all tumors are genetically heterogeneous, containing subclonal populations of cells that are defined by distinct mutations. Subclones can have unique phenotypes that influence disea...
    Speaker: Stephen Williams, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    2
    JUN 20, 2019 | 6:00 AM
    Precise DNA Sequencing: A Necessity for Precision Medicine
    Precise DNA Sequencing: A Necessity for Precision Medicine
    It has been noted by many in the community that for Precision Medicine to become a transformative reality, the underlying DNA and RNA sequence data have to become more precise. In my talk, I...
    Speaker: Jonas Korlach, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    1
    JUN 19, 2019 | 10:00 AM
    Getting started in 3D:  Ask an Expert
    Getting started in 3D: Ask an Expert
    DATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...
    Speaker: Mark Kennedy, Ph.D. , Richard Josephson, PhD
    Sponsored By: Thermo Fisher Scientific
    6
    JUN 18, 2019 | 11:00 AM
    Writing the NIH Research (R01) grant: Strategies for Success
    Writing the NIH Research (R01) grant: Strategies for Success
    DATE: June 18, 2019TIME: 11:00am PDT, 2:00pm EDT With highly competitive NIH budgets and ever-increasing restrictions on federal spending, getting noticed and winning...
    Speaker: Christopher Dant, PhD
    Sponsored By: Leica Microsystems
    13
    JUN 05, 2019 | 5:00 PM
    Everyday culture practice - Improving reproducibility in cell culture
    Everyday culture practice - Improving reproducibility in cell...
    DATE: June 5, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal chan...
    Speaker: Jessica Wagener, PhD
    Sponsored By: Eppendorf
    23 2
     
     
  • MAY 30, 2019 | 6:00 AM
    Improved Cancer Tracking Through Precision Quantification of Circulating Nucleic Acid Biomarkers
    Improved Cancer Tracking Through Precision Quantification of Circulating...
    Oncologists have many options when tasked with treating a patient’s cancer. Unfortunately, many cancer drugs and therapies come with potentially debilitating side effects. As such, it i...
    Speaker: Megan Dueck, PhD
    Presented at: Laboratory Testing & Automation Virtual Event Series 2019
    2
    MAY 21, 2019 | 7:00 AM
    Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
    Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key...
    DATE: May 21, 2019TIMEL 7:00am PT, 10:00am ET Human T cells are central effectors of immunity and cancer immunotherapy. CRISPR-based functional studies in T cells could prioriti...
    Speaker: Eric Shifrut, PhD
    Sponsored By: Thermo Fisher Scientific
    10 1
    MAY 16, 2019 | 4:00 PM
    Towards Standardized Workflows - A focus on microbiome insights
    Towards Standardized Workflows - A focus on microbiome insights
    DATE: May 16, 2019TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST The emergence of NGS is revolutionizing the microbiological sciences and transforming medicine. Deep sequencing has...
    Speaker: Rita Colwell, PhD , Christiane Honisch, PhD
    Sponsored By: Eppendorf
    10 2
    MAY 09, 2019 | 12:00 PM
    A Metagenomic Assay to Interrogate the Role of Virome and Microbiome in Cancer
    A Metagenomic Assay to Interrogate the Role of Virome and Microbiome...
    Screening to identify all known viruses and other pathogenic microorganisms including bacteria, fungus and parasites in human tumor tissues will provide a more comprehensive understanding of...
    Speaker: Erle Robertson, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: Agilent
    3
    MAY 09, 2019 | 10:30 AM
    Background and Troubleshooting for RT-PCR
    Background and Troubleshooting for RT-PCR
    Real-time PCR, or quantitative qPCR, is a commonly used molecular biology lab technique to determine the actual amount of PCR product at a given cycle. For quantitative reverse transcription...
    Speaker: Gillian Browne, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: MilliporeSigma
    4
     
     
  • MAY 09, 2019 | 9:00 AM
    Polygenic Risk Scores: PheWas and GWAS and Utility of Biobank Information
    Polygenic Risk Scores: PheWas and GWAS and Utility of Biobank...
    The advent of precision medicine largely depends on the creation of precise and accurate predictive tools. While most late-onset diseases are moderately to highly heritable, using genetic inf...
    Speaker: Guillaume Paré, MD, MSc, FRCPC
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: Illumina
    2 1
    MAY 09, 2019 | 6:00 AM
    AI-Driven Literature Curation for Determining Genomic Variant Pathogenicity
    AI-Driven Literature Curation for Determining Genomic Variant...
    Variant interpretation presents a bottleneck for many labs, posing a challenge to the broader adoption of precision medicine. The ACMG/AMP variant classification framework has provided a foun...
    Speaker: Mark Kiel, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    4
    MAY 08, 2019 | 10:30 AM
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders Using Ingenuity Pathway Analysis Software and OmicSoft OncoLand Datasets from QIAGEN
    Discovering Cellular Mechanisms and Biomarkers in Anti-PD1 Non-Responders...
    The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
    Speaker: Devendra Mistry, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
    MAY 08, 2019 | 10:30 AM
    C.E. CREDITS
    Using Networks to Understand Cancer Risk
    Using Networks to Understand Cancer Risk
    One of the central tenants of biology is that our genetics—our genotype—influences the physical characteristics we manifest—our phenotype. But with more than 25,000 human ge...
    Speaker: John Quackenbush, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
    MAY 08, 2019 | 6:00 AM
    C.E. CREDITS
    Novel DNA Methylation in Mammals
    Novel DNA Methylation in Mammals
    Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
    Speaker: Tao Wu, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
     
     
  • MAY 08, 2019 | 9:00 AM
    HPV-based cervical screening: from implementation to future possibilities
    HPV-based cervical screening: from implementation to future possibilities
    DATE: May 8, 2019TIME: 12:00am PDT In 2017 the first national cervical screening programs using human papillomavirus (HPV-based) primary screening were implemented. As these progr...
    Speaker: David Hawkes, PhD
    Sponsored By: Abbott Molecular Diagnostic
    8 2
    APR 25, 2019 | 6:00 AM
    Long-Read Sequencing and Infectious Disease: New Insights Into Longstanding Challenges
    Long-Read Sequencing and Infectious Disease: New Insights Into...
    To reduce the global burden diseases causes by infectious disease, including parasites and bacteria, scientists need better information about mechanisms of virulence, immune evasion, and drug...
    Speaker: Meredith Ashby, PhD
    Presented at: Infectious Disease Virtual Event Series 2019
    Sponsored By: PacBio
    2
    APR 18, 2019 | 9:00 AM
    Deep Learning in Optics
    Deep Learning in Optics
    DATE: April 18, 2019 TIME: 9:00am PDT...
    Speaker: Aydogan Ozcan, PhD , Hongda Wang, MS, BS , Yair Rivenson, PhD , Laurent Bentolila, PhD
    Sponsored By: Leica Microsystems
    4
    APR 10, 2019 | 1:30 PM
    Detection and Interpretation of Complex Myeloid Leukemia Mutations
    Detection and Interpretation of Complex Myeloid Leukemia Mutations
    Myeloid leukemias encompass a group of different diseases that include myeloproliferative neoplasms (MPN), myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). These diseases are d...
    Speaker: Véronique Laloux, PhD , Beate Litzenburger, Ph.D.
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    Sponsored By: QIAGEN
    6
    APR 10, 2019 | 1:30 PM
    Laboratory Medicine Beyond The Box: Value Based Health Care & Diagnostic Evidence
    Laboratory Medicine Beyond The Box: Value Based Health Care &...
    Integration of technology is influencing practice in the clinical laboratory and treatment of patients in the clinical practice arena. As laboratories begin to move from a volume to value mod...
    Speaker: Elizabeth Marlowe, PhD, D(ABMM) , Joanna Sickler, MPH, MBA
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    4
     
     
  • APR 10, 2019 | 1:30 PM
    Tools & Processes for Making Evidence-Based Policy Decisions
    Tools & Processes for Making Evidence-Based Policy Decisions
    The exponential advents of advances in techniques and types of molecular diagnostic testing, and modifying strategies for these tests, are encouraging; but these evolutions simultaneously con...
    Speaker: Eugean Jiwanmall, MPH, MBA
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    3
    APR 10, 2019 | 12:00 PM
    Digital Biosensors and the Internet of Biology
    Digital Biosensors and the Internet of Biology
    The prevailing philosophy in biological testing has been to focus on simple tests with easy to interpret information such as ELISA or lateral flow assays. At the same time, there has been a d...
    Speaker: Brett Goldsmith, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    4
    APR 10, 2019 | 12:00 PM
    Best Practices for Implementing NGS and Positioning for Future Growth: Perspectives from 2 Labs
    Best Practices for Implementing NGS and Positioning for Future...
    Personalized medicine driven by genomic-based treatments continues to increase in importance. Representatives from two distinct healthcare entities – a regional reference lab and commun...
    Speaker: Tony Magliocco, MD , Keith Gligorich, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    Sponsored By: Illumina
    7
    APR 10, 2019 | 12:00 PM
    Transforming Oncology with ctDNA+ctRNA Liquid Biopsy Solutions
    Transforming Oncology with ctDNA+ctRNA Liquid Biopsy Solutions
    Determining which patients would derive clinical benefit from immunotherapy is a compelling clinical question. Biomarkers have been shown to predict therapy outcome in various types of cancer...
    Speaker: Shidong Jia, MD, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    4
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