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    Cancer Molecular Biology

    Molecular biology plays an important role in the diagnosis and treatment of cancer. On a biological level, the development of cancer is characterized by the acquisition of genetic mutations which cause abnormal cell growth, eventually resulting in malignant disease. Understanding how molecular damage can cause these cancer-driving mutations can help design optimal treatment regimens

    Webinars

    • APR 10, 2019 | 10:30 AM
      A Sample to Insight Solution for Detection and Classification of Challenging Pathogenic BRCA Mutations
      A Sample to Insight Solution for Detection and Classification...
      The BRCA1 and BRCA2 genes represent the best examples of the modern understanding of cancer molecular genetics. Testing for germline and somatic mutations in BRCA 1/2 has gradually become com...
      Speaker: Anika Joecker, PhD , Jennifer Poitras, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      Sponsored By: QIAGEN
      5
      APR 10, 2019 | 10:30 AM
      Better Knowledge, Better Care: Precision Medicine for Any Cancer, Any Assay, on Your Platform
      Better Knowledge, Better Care: Precision Medicine for Any Cancer,...
      QIAGEN helps your team focus on the opportunities, not the obstacles, with an end-to-end clinical testing solution. During this talk, we will present our clinical decision support solutions,...
      Speaker: Sheryl Elkin, PhD , Dan Richards, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      Sponsored By: QIAGEN
      2
      APR 10, 2019 | 10:30 AM
      CRISPR-Chip: Detection of Unamplified Target Genes via CRISPR/Cas9 Immobilized on a Graphene Biosensors
      CRISPR-Chip: Detection of Unamplified Target Genes via CRISPR/Cas9...
      CRISPR-chip combines two powerful technologies ,CRISPR and Graphene, for rapid detection of nucleic acids. This talk will focus on design and fabrication of CRISPR-chip and its potential util...
      Speaker: Kiana Aran, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      4
      APR 10, 2019 | 9:00 AM
      Novel Applications of Molecular Diagnostics in Infectious Diseases
      Novel Applications of Molecular Diagnostics in Infectious Diseases
      The laboratory diagnosis of infectious diseases has traditionally relied on recovery of pathogens in cultures and for many infections, this approach remains the standard of care. The developm...
      Speaker: Esther Babady, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      7
      APR 10, 2019 | 9:00 AM
      CRISPR Proteins: Enabling the Next-Generation of Molecular Diagnostics
      CRISPR Proteins: Enabling the Next-Generation of Molecular Diagnostics
      Mammoth Biosciences is developing next-generation CRISPR platforms to build rapid, point-of-care molecular diagnostics. Our innovative DETECTR technology leverages novel CRISPR proteins whose...
      Speaker: James Broughton
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      5
      APR 10, 2019 | 9:00 AM
      Validation and Implementation of Quantitative Molecular Assays
      Validation and Implementation of Quantitative Molecular Assays
      Regulatory requirements for verification and validation are complex and often cause confusion among clinical laboratorians, especially in regards to quantitative molecular assays. This presen...
      Speaker: Morgan Pence, PhD, D(ABMM)
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      Sponsored By: Diasorin
      8
      APR 10, 2019 | 7:30 AM
      Keynote Presentation: Clinical Lab 2.0 - How Laboratories Can Thrive in a Value Based Care System
      Keynote Presentation: Clinical Lab 2.0 - How Laboratories Can...
      As reimbursement changes and healthcare moves towards value-based models, the clinical laboratory is faced with the challenge of redefining its value outside the cost per test. This session...
      Speaker: Michael Crossey, MD, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      3
      APR 10, 2019 | 6:00 AM
      Bio-Rad Unity as a Solution for Molecular Quality Control Data Management
      Bio-Rad Unity as a Solution for Molecular Quality Control Data...
      Management of complex quality control (QC) data is essential to insure high quality patient care and maintain regulatory compliance within clinical laboratories. Robust software solutions fo...
      Speaker: Duane Newton, PhD, D(ABMM), FIDSA
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      Sponsored By: Bio-Rad Laboratories
      10
      APR 10, 2019 | 6:00 AM
      Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
      Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
      Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen detection, genotyping, and disease monitoring. We combine the RNA- targeting CRISPR effector Cas13 with...
      Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      6
      MAR 28, 2019 | 12:00 PM
      The Intersection of Nutrition, Microbiome and Medical Cannabis
      The Intersection of Nutrition, Microbiome and Medical Cannabis
      Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
      Speaker: Debra Kimless, MD
      Presented at: Cannabis Sciences Virtual Event Series 2019
      6
      MAR 28, 2019 | 10:30 AM
      Medical Cannabis Pharmacogenomics and Drug Interactions
      Medical Cannabis Pharmacogenomics and Drug Interactions
      The therapeutic applications of medical cannabis and cannabinoid drugs is controversial, however the number of medical conditions in which cannabinoids and cannabis have shown promise as ther...
      Speaker: Jahan Marcu, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2019
      3
      MAR 27, 2019 | 1:30 PM
      The Role of LIMS in Achieving ISO 17025 Compliance in Cannabis Testing Laboratories
      The Role of LIMS in Achieving ISO 17025 Compliance in Cannabis...
      If your lab has decided to apply for ISO/IEC 17025 accreditation as your state requires it or to demonstrate the reliability of your lab results to potential customers, you may think what nex...
      Speaker: Arun Apte
      Presented at: Cannabis Sciences Virtual Event Series 2019
      13
      MAR 27, 2019 | 12:00 PM
      Controlling Terpenes and Cannabinoids in Flower and Extract
      Controlling Terpenes and Cannabinoids in Flower and Extract
      The cannabis industry has realized that not just one or two compounds of the plant are important for a variety of medical indications. A plethora of metabolites, e.g. terpenes, flavonoids and...
      Speaker: Markus Roggen, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2019
      3 1
      MAR 27, 2019 | 6:00 AM
      Automating Cannabis Testing with LIMS and Laboratory Automation
      Automating Cannabis Testing with LIMS and Laboratory Automation
      Automating Cannabis Testing with Laboratory Information Management Systems (LIMS) Software systems automate not only key aspects of laboratory testing, but provide a comprehensive data manage...
      Speaker: Christine Paszko, PhD, MT (ASCP)
      Presented at: Cannabis Sciences Virtual Event Series 2019
      2
      MAR 26, 2019 | 2:00 PM
      The Role of Endosomes in Prostate Cancer
      The Role of Endosomes in Prostate Cancer
      DATE:  March 26, 2019TIME:  2:00pm PDT, 5:00pm EDT  Prostate cancer is the second most common form of cancer in males, affecting one in eight men by the time t...
      Speaker: Ian Johnson, BSc., Ph.D
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      MAR 21, 2019 | 7:00 AM
      Phenotyping the tumor micro-environment with advanced tissue-based multiplexing assays
      Phenotyping the tumor micro-environment with advanced tissue-based...
      DATE:  March 21,  2019TIME:  7:00am PDT, 10:00am EDT The benefits of multiplex immunohistochemistry assays for tissue analysis are numerous. High-level multipl...
      Speaker: Katir Patel, PhD
      Sponsored By: Ultivue
      11
      MAR 05, 2019 | 10:00 AM
      Comprehensive Capture of Human Neuropathology by Multiplexed Ion Beam Imaging (MIBI)
      Comprehensive Capture of Human Neuropathology by Multiplexed Ion...
      DATE: March 5, 2019TIME:  10:00am PSTSingle cell analysis, starting with the earliest low parameter fluorescent experiments, helped define the major cell subsets of human ce...
      Speaker: Sean Bendall, PhD
      Sponsored By: IONpath
      2 1
      MAR 05, 2019 | 9:00 AM
      Strategies to normalize miRNA expression in serum and plasma.
      Strategies to normalize miRNA expression in serum and plasma.
      DATE:  March 5, 2019TIME:  09:00am PST, 12:00pm EST MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post tran...
      Speaker: Emily Zeringer , Harita Veereshlingam, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      7
      FEB 27, 2019 | 3:00 PM
      Do You Have the Gut-on-a-Chip?
      Do You Have the Gut-on-a-Chip?
      In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
      Speaker: Elena Naumovska, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      2
      FEB 27, 2019 | 3:00 PM
      Automation Meets Cell Separation: Primary Cells for Drug Discovery Assays
      Automation Meets Cell Separation: Primary Cells for Drug Discovery...
      Whether you are performing killing assays, immunophenotyping of TILs, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery...
      Speaker: Lotta Raty
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Miltenyi Biotec
      2
      FEB 27, 2019 | 1:30 PM
      Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner, for Optimal Identification of Rare Genomic Events Using TruSightTM Oncology 500
      Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner,...
      NTRK fusions are rare but important recent biomarkers linked to response to new TRK inhibitors. Comprehensive genomic profiling on all solid tumors permits detection of rare genomic events an...
      Speaker: Phillip Febbo, MD , Maude Champagne
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Illumina
      4
      FEB 27, 2019 | 12:00 PM
      Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint Blockade in Melanoma
      Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint...
      Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
      Speaker: Sarah Warren, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: NanoString Technologies
      1
      FEB 27, 2019 | 10:30 AM
      Developing Precision Combination Therapies to Overcome Evolution of Therapeutic Resistance
      Developing Precision Combination Therapies to Overcome Evolution...
      Recent clinical successes in cancer genome-inspired personalized medicine have been a major breakthrough in drug discovery. However, 98% of the patients have an incomplete therapeutic respons...
      Speaker: Khyati Shah, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 8:00 AM
      Prepare for success: GMP cell banks as part of a staged, standardized, platform-style cell production process
      Prepare for success: GMP cell banks as part of a staged, standardized,...
      DATE:  February 27, 2019TIME:  8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
      Speaker: Benjamin Fryer
      Sponsored By: Thermo Fisher Scientific/Gibco
      9
    APR 10, 2019 | 10:30 AM
    A Sample to Insight Solution for Detection and Classification of Challenging Pathogenic BRCA Mutations
    A Sample to Insight Solution for Detection and Classification...
    The BRCA1 and BRCA2 genes represent the best examples of the modern understanding of cancer molecular genetics. Testing for germline and somatic mutations in BRCA 1/2 has gradually become com...
    Speaker: Anika Joecker, PhD , Jennifer Poitras, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    Sponsored By: QIAGEN
    5
    APR 10, 2019 | 10:30 AM
    Better Knowledge, Better Care: Precision Medicine for Any Cancer, Any Assay, on Your Platform
    Better Knowledge, Better Care: Precision Medicine for Any Cancer,...
    QIAGEN helps your team focus on the opportunities, not the obstacles, with an end-to-end clinical testing solution. During this talk, we will present our clinical decision support solutions,...
    Speaker: Sheryl Elkin, PhD , Dan Richards, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    Sponsored By: QIAGEN
    2
    APR 10, 2019 | 10:30 AM
    CRISPR-Chip: Detection of Unamplified Target Genes via CRISPR/Cas9 Immobilized on a Graphene Biosensors
    CRISPR-Chip: Detection of Unamplified Target Genes via CRISPR/Cas9...
    CRISPR-chip combines two powerful technologies ,CRISPR and Graphene, for rapid detection of nucleic acids. This talk will focus on design and fabrication of CRISPR-chip and its potential util...
    Speaker: Kiana Aran, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    4
    APR 10, 2019 | 9:00 AM
    Novel Applications of Molecular Diagnostics in Infectious Diseases
    Novel Applications of Molecular Diagnostics in Infectious Diseases
    The laboratory diagnosis of infectious diseases has traditionally relied on recovery of pathogens in cultures and for many infections, this approach remains the standard of care. The developm...
    Speaker: Esther Babady, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    7
    APR 10, 2019 | 9:00 AM
    CRISPR Proteins: Enabling the Next-Generation of Molecular Diagnostics
    CRISPR Proteins: Enabling the Next-Generation of Molecular Diagnostics
    Mammoth Biosciences is developing next-generation CRISPR platforms to build rapid, point-of-care molecular diagnostics. Our innovative DETECTR technology leverages novel CRISPR proteins whose...
    Speaker: James Broughton
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    5
     
     
  • APR 10, 2019 | 9:00 AM
    Validation and Implementation of Quantitative Molecular Assays
    Validation and Implementation of Quantitative Molecular Assays
    Regulatory requirements for verification and validation are complex and often cause confusion among clinical laboratorians, especially in regards to quantitative molecular assays. This presen...
    Speaker: Morgan Pence, PhD, D(ABMM)
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    Sponsored By: Diasorin
    8
    APR 10, 2019 | 7:30 AM
    Keynote Presentation: Clinical Lab 2.0 - How Laboratories Can Thrive in a Value Based Care System
    Keynote Presentation: Clinical Lab 2.0 - How Laboratories Can...
    As reimbursement changes and healthcare moves towards value-based models, the clinical laboratory is faced with the challenge of redefining its value outside the cost per test. This session...
    Speaker: Michael Crossey, MD, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    3
    APR 10, 2019 | 6:00 AM
    Bio-Rad Unity as a Solution for Molecular Quality Control Data Management
    Bio-Rad Unity as a Solution for Molecular Quality Control Data...
    Management of complex quality control (QC) data is essential to insure high quality patient care and maintain regulatory compliance within clinical laboratories. Robust software solutions fo...
    Speaker: Duane Newton, PhD, D(ABMM), FIDSA
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    Sponsored By: Bio-Rad Laboratories
    10
    APR 10, 2019 | 6:00 AM
    Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
    Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
    Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen detection, genotyping, and disease monitoring. We combine the RNA- targeting CRISPR effector Cas13 with...
    Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    6
    MAR 28, 2019 | 12:00 PM
    The Intersection of Nutrition, Microbiome and Medical Cannabis
    The Intersection of Nutrition, Microbiome and Medical Cannabis
    Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
    Speaker: Debra Kimless, MD
    Presented at: Cannabis Sciences Virtual Event Series 2019
    6
     
     
  • MAR 28, 2019 | 10:30 AM
    Medical Cannabis Pharmacogenomics and Drug Interactions
    Medical Cannabis Pharmacogenomics and Drug Interactions
    The therapeutic applications of medical cannabis and cannabinoid drugs is controversial, however the number of medical conditions in which cannabinoids and cannabis have shown promise as ther...
    Speaker: Jahan Marcu, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2019
    3
    MAR 27, 2019 | 1:30 PM
    The Role of LIMS in Achieving ISO 17025 Compliance in Cannabis Testing Laboratories
    The Role of LIMS in Achieving ISO 17025 Compliance in Cannabis...
    If your lab has decided to apply for ISO/IEC 17025 accreditation as your state requires it or to demonstrate the reliability of your lab results to potential customers, you may think what nex...
    Speaker: Arun Apte
    Presented at: Cannabis Sciences Virtual Event Series 2019
    13
    MAR 27, 2019 | 12:00 PM
    Controlling Terpenes and Cannabinoids in Flower and Extract
    Controlling Terpenes and Cannabinoids in Flower and Extract
    The cannabis industry has realized that not just one or two compounds of the plant are important for a variety of medical indications. A plethora of metabolites, e.g. terpenes, flavonoids and...
    Speaker: Markus Roggen, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2019
    3 1
    MAR 27, 2019 | 6:00 AM
    Automating Cannabis Testing with LIMS and Laboratory Automation
    Automating Cannabis Testing with LIMS and Laboratory Automation
    Automating Cannabis Testing with Laboratory Information Management Systems (LIMS) Software systems automate not only key aspects of laboratory testing, but provide a comprehensive data manage...
    Speaker: Christine Paszko, PhD, MT (ASCP)
    Presented at: Cannabis Sciences Virtual Event Series 2019
    2
    MAR 26, 2019 | 2:00 PM
    The Role of Endosomes in Prostate Cancer
    The Role of Endosomes in Prostate Cancer
    DATE:  March 26, 2019TIME:  2:00pm PDT, 5:00pm EDT  Prostate cancer is the second most common form of cancer in males, affecting one in eight men by the time t...
    Speaker: Ian Johnson, BSc., Ph.D
    Sponsored By: Thermo Fisher Scientific/Gibco
    7
     
     
  • MAR 21, 2019 | 7:00 AM
    Phenotyping the tumor micro-environment with advanced tissue-based multiplexing assays
    Phenotyping the tumor micro-environment with advanced tissue-based...
    DATE:  March 21,  2019TIME:  7:00am PDT, 10:00am EDT The benefits of multiplex immunohistochemistry assays for tissue analysis are numerous. High-level multipl...
    Speaker: Katir Patel, PhD
    Sponsored By: Ultivue
    11
    MAR 05, 2019 | 10:00 AM
    Comprehensive Capture of Human Neuropathology by Multiplexed Ion Beam Imaging (MIBI)
    Comprehensive Capture of Human Neuropathology by Multiplexed Ion...
    DATE: March 5, 2019TIME:  10:00am PSTSingle cell analysis, starting with the earliest low parameter fluorescent experiments, helped define the major cell subsets of human ce...
    Speaker: Sean Bendall, PhD
    Sponsored By: IONpath
    2 1
    MAR 05, 2019 | 9:00 AM
    Strategies to normalize miRNA expression in serum and plasma.
    Strategies to normalize miRNA expression in serum and plasma.
    DATE:  March 5, 2019TIME:  09:00am PST, 12:00pm EST MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post tran...
    Speaker: Emily Zeringer , Harita Veereshlingam, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    7
    FEB 27, 2019 | 3:00 PM
    Do You Have the Gut-on-a-Chip?
    Do You Have the Gut-on-a-Chip?
    In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
    Speaker: Elena Naumovska, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    2
    FEB 27, 2019 | 3:00 PM
    Automation Meets Cell Separation: Primary Cells for Drug Discovery Assays
    Automation Meets Cell Separation: Primary Cells for Drug Discovery...
    Whether you are performing killing assays, immunophenotyping of TILs, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery...
    Speaker: Lotta Raty
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Miltenyi Biotec
    2
     
     
  • FEB 27, 2019 | 1:30 PM
    Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner, for Optimal Identification of Rare Genomic Events Using TruSightTM Oncology 500
    Comprehensive NTRK Fusion Detection, Agnostic of the Fusion Partner,...
    NTRK fusions are rare but important recent biomarkers linked to response to new TRK inhibitors. Comprehensive genomic profiling on all solid tumors permits detection of rare genomic events an...
    Speaker: Phillip Febbo, MD , Maude Champagne
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Illumina
    4
    FEB 27, 2019 | 12:00 PM
    Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint Blockade in Melanoma
    Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint...
    Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
    Speaker: Sarah Warren, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: NanoString Technologies
    1
    FEB 27, 2019 | 10:30 AM
    Developing Precision Combination Therapies to Overcome Evolution of Therapeutic Resistance
    Developing Precision Combination Therapies to Overcome Evolution...
    Recent clinical successes in cancer genome-inspired personalized medicine have been a major breakthrough in drug discovery. However, 98% of the patients have an incomplete therapeutic respons...
    Speaker: Khyati Shah, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 8:00 AM
    Prepare for success: GMP cell banks as part of a staged, standardized, platform-style cell production process
    Prepare for success: GMP cell banks as part of a staged, standardized,...
    DATE:  February 27, 2019TIME:  8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
    Speaker: Benjamin Fryer
    Sponsored By: Thermo Fisher Scientific/Gibco
    9
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