Follow
Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
-
JAN 09, 2023Cell & Molecular Biology
Polycystic kidney disease (PKD) is a common genetic disorder, and it's thought to affect over 12 million people every ye ...Written By: Carmen LeitchJAN 06, 2023Earth & The Environment
Moira Rodriguez is a 3rd-year Biological Sciences PhD student at the University of Nebraska-Lincoln (UNL) studying plant ...Written By: Laurence Tognetti, MScDEC 30, 2022Health & Medicine
Our immune system has to be able to rapidly mount a response to pathogenic invaders, wounds, and other injuries. But it ...Written By: Carmen LeitchDEC 23, 2022Health & Medicine
While about 30,000 Americans are confirmed to have Lyme disease every year, the CDC has estimated that the number may be ...Written By: Carmen LeitchDEC 15, 2022Cell & Molecular Biology
Aging is linked to a decline in good health and an increase in the risk of many different diseases. People even die simp ...Written By: Carmen LeitchDEC 13, 2022Plants & Animals
Scientists believe COVID-19 is still highly transmissible between species based on computer simulations of mammalian cro ...Written By: Kerry CharronNOV 28, 2022Drug Discovery & Development
An experimental orally-administered drug reduces 'bad cholesterol' in mice by 70%. The corresponding research wa ...Written By: Annie LennonNOV 08, 2022Drug Discovery & Development
Cystic fibrosis (CF) affects over 100,000 people worldwide and is caused by one of several known mutations in the CFTR ( ...Written By: Anusha NaganathanNOV 05, 2022Health & Medicine
A handful of almonds a day could keep your gut healthy by promoting the production of a short-chain fatty acid known as ...Written By: Joshua AehOCT 31, 2022Genetics & Genomics
There is viral DNA in the human genome, and each instance traces back to an ancestor who was infected with a retrovirus. ...Written By: Carmen LeitchOCT 24, 2022Technology
Breast cancer is among the most common types of cancer, particularly among women. In fact, other than skin cancers, it i ...Written By: Ryan VingumOCT 13, 2022Cancer
Point mutations change one or very few nucleotides in DNA, but they cause an estimated 30,000 genetic diseases in humans ...OCT 03, 2022Technology
In a recent study published in Science Robotics, a team of researchers led by the Massachusetts Institute of Technology ...Written By: Laurence Tognetti, MScSEP 26, 2022Clinical & Molecular DX
Diabetes is a chronic disease that causes high levels of blood glucose. This is a result of the pancreas producing insuf ...Written By: Zoe MichaudSEP 25, 2022Microbiology
New research has suggested that bacteria that live in the human mouth could work as model organisms that can help us fin ...Written By: Carmen LeitchSEP 19, 2022Neuroscience
There are important neural circuits in the hypothalamus that help us sense our own hunger and when we feel full after a ...Written By: Carmen LeitchSEP 18, 2022Cell & Molecular Biology
It is extremely challenging to study human development. There are animal models that can tell us how general aspects of ...Written By: Carmen LeitchSEP 14, 2022Drug Discovery & Development
Media Survey Panel vs. Media Screen: An Interview with R&D Scientist Catherine Nguyen on Benefit of Using a Media Survey ...Sponsored By: FUJIFILM Irvine ScientificSEP 14, 2022Genetics & Genomics
Scientists are beginning to reveal the secrets of the long, repetitive sequences in the human genome that were once writ ...Written By: Carmen LeitchSEP 13, 2022Cancer
Introduction Cancer is the second leading cause of death globally. According to estimates from the American Cancer Socie ...Sponsored By: Sino BiologicalSEP 07, 2022Drug Discovery & Development
Achieving high cell densities in long-term cultures is often a challenge facing bioprocessing manufacturers, and one tha ...Sponsored By: FUJIFILM Irvine ScientificSEP 07, 2022Drug Discovery & Development
Diabetes is a chronic disease that requires constant monitoring. Patients have to check the level of sugar, or glucose i ...Written By: Carmen LeitchAUG 26, 2022Genetics & Genomics
Stem cells hold tremendous potential, because they can specialize into any type of cell. During development, stem cells ...Written By: Carmen LeitchAUG 24, 2022Immunology
T cells are on the front lines of the immune system, monitoring the body for pathogens, and springing into action when t ...Written By: Carmen Leitch
JAN 09, 2023
Cell & Molecular Biology
Polycystic kidney disease (PKD) is a common genetic disorder, and it's thought to affect over 12 million people every ye
...
Written By:
Carmen Leitch
JAN 06, 2023
Earth & The Environment
Moira Rodriguez is a 3rd-year Biological Sciences PhD student at the University of Nebraska-Lincoln (UNL) studying plant
...
Written By:
Laurence Tognetti, MSc
DEC 30, 2022
Health & Medicine
Our immune system has to be able to rapidly mount a response to pathogenic invaders, wounds, and other injuries. But it
...
Written By:
Carmen Leitch
DEC 23, 2022
Health & Medicine
While about 30,000 Americans are confirmed to have Lyme disease every year, the CDC has estimated that the number may be
...
Written By:
Carmen Leitch
DEC 15, 2022
Cell & Molecular Biology
Aging is linked to a decline in good health and an increase in the risk of many different diseases. People even die simp
...
Written By:
Carmen Leitch
DEC 13, 2022
Plants & Animals
Scientists believe COVID-19 is still highly transmissible between species based on computer simulations of mammalian cro
...
Written By:
Kerry Charron
NOV 28, 2022
Drug Discovery & Development
An experimental orally-administered drug reduces 'bad cholesterol' in mice by 70%. The corresponding research wa
...
Written By:
Annie Lennon
NOV 08, 2022
Drug Discovery & Development
Cystic fibrosis (CF) affects over 100,000 people worldwide and is caused by one of several known mutations in the CFTR (
...
Written By:
Anusha Naganathan
NOV 05, 2022
Health & Medicine
A handful of almonds a day could keep your gut healthy by promoting the production of a short-chain fatty acid known as
...
Written By:
Joshua Aeh
OCT 31, 2022
Genetics & Genomics
There is viral DNA in the human genome, and each instance traces back to an ancestor who was infected with a retrovirus.
...
Written By:
Carmen Leitch
OCT 24, 2022
Technology
Breast cancer is among the most common types of cancer, particularly among women. In fact, other than skin cancers, it i
...
Written By:
Ryan Vingum
OCT 13, 2022
Cancer
Point mutations change one or very few nucleotides in DNA, but they cause an estimated 30,000 genetic diseases in humans
...
OCT 03, 2022
Technology
In a recent study published in Science Robotics, a team of researchers led by the Massachusetts Institute of Technology
...
Written By:
Laurence Tognetti, MSc
SEP 26, 2022
Clinical & Molecular DX
Diabetes is a chronic disease that causes high levels of blood glucose. This is a result of the pancreas producing insuf
...
Written By:
Zoe Michaud
SEP 25, 2022
Microbiology
New research has suggested that bacteria that live in the human mouth could work as model organisms that can help us fin
...
Written By:
Carmen Leitch
SEP 19, 2022
Neuroscience
There are important neural circuits in the hypothalamus that help us sense our own hunger and when we feel full after a
...
Written By:
Carmen Leitch
SEP 18, 2022
Cell & Molecular Biology
It is extremely challenging to study human development. There are animal models that can tell us how general aspects of
...
Written By:
Carmen Leitch
SEP 14, 2022
Drug Discovery & Development
Media Survey Panel vs. Media Screen: An Interview with R&D Scientist Catherine Nguyen on Benefit of Using a Media Survey
...
Sponsored By:
FUJIFILM Irvine Scientific
SEP 14, 2022
Genetics & Genomics
Scientists are beginning to reveal the secrets of the long, repetitive sequences in the human genome that were once writ
...
Written By:
Carmen Leitch
SEP 13, 2022
Cancer
Introduction Cancer is the second leading cause of death globally. According to estimates from the American Cancer Socie
...
Sponsored By:
Sino Biological
SEP 07, 2022
Drug Discovery & Development
Achieving high cell densities in long-term cultures is often a challenge facing bioprocessing manufacturers, and one tha
...
Sponsored By:
FUJIFILM Irvine Scientific
SEP 07, 2022
Drug Discovery & Development
Diabetes is a chronic disease that requires constant monitoring. Patients have to check the level of sugar, or glucose i
...
Written By:
Carmen Leitch
AUG 26, 2022
Genetics & Genomics
Stem cells hold tremendous potential, because they can specialize into any type of cell. During development, stem cells
...
Written By:
Carmen Leitch
AUG 24, 2022
Immunology
T cells are on the front lines of the immune system, monitoring the body for pathogens, and springing into action when t
...
Written By:
Carmen Leitch