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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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MAY 17, 2021Cell & Molecular Biology
Human pluripotent stem cell (hPSC) lines are now commonly used across the globe. In the lab, researchers rely on hPSCs t ...Sponsored By: STEMCELL TechnologiesMAY 06, 2021Cell & Molecular Biology
Some genetic diseases are caused by inborn errors - genetic mutations that we're born with and that end up in every cell ...Written By: Carmen LeitchMAY 05, 2021Immunology
Three-dimensional (3D) printing has become a common technique over the past two decades. Now, the technique has been ado ...Written By: Caroline WallaceAPR 22, 2021Cell & Molecular Biology
Research has found that in several human disorders that impact breathing, including two that affect infants, there is an ...Written By: Carmen LeitchAPR 19, 2021Cell & Molecular Biology
New research has shown how variants in an immune gene can lead to a high risk of developing the autoimmune disorder rheu ...Written By: Carmen LeitchAPR 02, 2021Drug Discovery & Development
What are tropical and neglected diseases? Chronic infections that plague developing nations with often little financial ...Written By: Nouran AminMAR 30, 2021Immunology
The immune system encompasses a powerful arsenal of weapons against pathogenic threats. But what stops healthy tissues i ...Written By: Tara FernandesMAR 29, 2021Cancer
Novel research published in Genome Biology investigates the cellular mechanisms at work during cancer metastasis using n ...Written By: Kathryn DeMuth SullivanMAR 24, 2021Cardiology
Scientists have found that it may be possible for people with a rare genetic disorder to prevent fatal strokes by taking ...Written By: Carmen LeitchMAR 24, 2021Drug Discovery & Development
Researchers have found that that three common antiviral and antimalarial therapeutics may be effective in vitro at targe ...Written By: Nouran AminMAR 23, 2021Cell & Molecular Biology
Patients with a disease often see specialists, and there may not be much communication among them when individuals suffe ...Written By: Carmen LeitchMAR 18, 2021Drug Discovery & Development
Researchers have developed a prototype for a new kind of cancer immunotherapy. The therapy uses engineered T-cells to ta ...Written By: Annie LennonMAR 14, 2021Genetics & Genomics
Preterm birth is when a baby is born before the 37th week of pregnancy. The liver, lungs & brain undergo a crucial devel ...Written By: Carmen LeitchMAR 02, 2021Cell & Molecular Biology
Retroviruses can infect cells and insert themselves into the genetic code of their host. Sometime in the past 50,000 yea ...Written By: Carmen LeitchFEB 28, 2021Genetics & Genomics
Research scientists have to be able to manipulate molecules in cells to learn more about their function, what goes wrong ...Written By: Carmen LeitchFEB 21, 2021Genetics & Genomics
Spina bifida is a birth defect that happens when the spinal cord of a developing infant doesn't form correctly, because ...Written By: Carmen LeitchFEB 18, 2021Cell & Molecular Biology
Researchers may have identified a new treatment target for a deadly form of brain cancer. Inhibiting an enzyme called PR ...Written By: Carmen LeitchFEB 16, 2021Microbiology
Viruses that infect bacteria are called phages, and scientists have been interested in whether they can be used to targe ...Written By: Carmen LeitchFEB 07, 2021Cell & Molecular Biology
Animals grow from what looks like a clump of cells, but those cells organize into specific patterns, laying the right fo ...Written By: Carmen LeitchJAN 31, 2021Genetics & Genomics
Cancer is typically related to problems in cells' genomes that lead to uncontrolled cell growth, and the formation of tu ...Written By: Carmen LeitchJAN 24, 2021Cannabis Sciences
Researchers from the University of Queensland, in collaboration with Botanix Pharmaceuticals Limited, have found that ca ...Written By: Annie LennonJAN 20, 2021Microbiology
For the first time, a synthetic version of a non-psychoactive molecule found in marijuana has been shown to kill pathoge ...Written By: Carmen LeitchJAN 10, 2021Cell & Molecular Biology
Mosquitoes are killers; they are thought to be responsible for the deaths of millions of people every year because of th ...Written By: Carmen LeitchJAN 01, 2021Microbiology
Reporting in Nature, scientists have identified a new group of compounds that may help us get out of the antibiotic-resi ...Written By: Carmen Leitch
MAY 17, 2021
Cell & Molecular Biology
Human pluripotent stem cell (hPSC) lines are now commonly used across the globe. In the lab, researchers rely on hPSCs t
...
Sponsored By:
STEMCELL Technologies
MAY 06, 2021
Cell & Molecular Biology
Some genetic diseases are caused by inborn errors - genetic mutations that we're born with and that end up in every cell
...
Written By:
Carmen Leitch
MAY 05, 2021
Immunology
Three-dimensional (3D) printing has become a common technique over the past two decades. Now, the technique has been ado
...
Written By:
Caroline Wallace
APR 22, 2021
Cell & Molecular Biology
Research has found that in several human disorders that impact breathing, including two that affect infants, there is an
...
Written By:
Carmen Leitch
APR 19, 2021
Cell & Molecular Biology
New research has shown how variants in an immune gene can lead to a high risk of developing the autoimmune disorder rheu
...
Written By:
Carmen Leitch
APR 02, 2021
Drug Discovery & Development
What are tropical and neglected diseases? Chronic infections that plague developing nations with often little financial
...
Written By:
Nouran Amin
MAR 30, 2021
Immunology
The immune system encompasses a powerful arsenal of weapons against pathogenic threats. But what stops healthy tissues i
...
Written By:
Tara Fernandes
MAR 29, 2021
Cancer
Novel research published in Genome Biology investigates the cellular mechanisms at work during cancer metastasis using n
...
Written By:
Kathryn DeMuth Sullivan
MAR 24, 2021
Cardiology
Scientists have found that it may be possible for people with a rare genetic disorder to prevent fatal strokes by taking
...
Written By:
Carmen Leitch
MAR 24, 2021
Drug Discovery & Development
Researchers have found that that three common antiviral and antimalarial therapeutics may be effective in vitro at targe
...
Written By:
Nouran Amin
MAR 23, 2021
Cell & Molecular Biology
Patients with a disease often see specialists, and there may not be much communication among them when individuals suffe
...
Written By:
Carmen Leitch
MAR 18, 2021
Drug Discovery & Development
Researchers have developed a prototype for a new kind of cancer immunotherapy. The therapy uses engineered T-cells to ta
...
Written By:
Annie Lennon
MAR 14, 2021
Genetics & Genomics
Preterm birth is when a baby is born before the 37th week of pregnancy. The liver, lungs & brain undergo a crucial devel
...
Written By:
Carmen Leitch
MAR 02, 2021
Cell & Molecular Biology
Retroviruses can infect cells and insert themselves into the genetic code of their host. Sometime in the past 50,000 yea
...
Written By:
Carmen Leitch
FEB 28, 2021
Genetics & Genomics
Research scientists have to be able to manipulate molecules in cells to learn more about their function, what goes wrong
...
Written By:
Carmen Leitch
FEB 21, 2021
Genetics & Genomics
Spina bifida is a birth defect that happens when the spinal cord of a developing infant doesn't form correctly, because
...
Written By:
Carmen Leitch
FEB 18, 2021
Cell & Molecular Biology
Researchers may have identified a new treatment target for a deadly form of brain cancer. Inhibiting an enzyme called PR
...
Written By:
Carmen Leitch
FEB 16, 2021
Microbiology
Viruses that infect bacteria are called phages, and scientists have been interested in whether they can be used to targe
...
Written By:
Carmen Leitch
FEB 07, 2021
Cell & Molecular Biology
Animals grow from what looks like a clump of cells, but those cells organize into specific patterns, laying the right fo
...
Written By:
Carmen Leitch
JAN 31, 2021
Genetics & Genomics
Cancer is typically related to problems in cells' genomes that lead to uncontrolled cell growth, and the formation of tu
...
Written By:
Carmen Leitch
JAN 24, 2021
Cannabis Sciences
Researchers from the University of Queensland, in collaboration with Botanix Pharmaceuticals Limited, have found that ca
...
Written By:
Annie Lennon
JAN 20, 2021
Microbiology
For the first time, a synthetic version of a non-psychoactive molecule found in marijuana has been shown to kill pathoge
...
Written By:
Carmen Leitch
JAN 10, 2021
Cell & Molecular Biology
Mosquitoes are killers; they are thought to be responsible for the deaths of millions of people every year because of th
...
Written By:
Carmen Leitch
JAN 01, 2021
Microbiology
Reporting in Nature, scientists have identified a new group of compounds that may help us get out of the antibiotic-resi
...
Written By:
Carmen Leitch