Chromatography: an analytical technique commonly used for separating a mixture of chemical substances into its individual components, so that the individual components can be thoroughly analyzed. . The mixture is dissolved in a fluid called the mobile phase, which carries it through a structure holding another material called the stationary phase. The various constituents of the mixture travel at different speeds, causing them to separate. The separation is based on differential partitioning between the mobile and stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus affect the separation.
-
Unlock the full potential of your LC-MS system with Thermo Scientific™ Chromeleon™ software features. This webinar will demonstrate the system suitability test with intelligent r...
Efficient purification of plasmids, proteins, and antibodies is critical for drug target identification, drug candidate development, and fundamental research. However, traditional column-bas...
Hydrogen/deuterium exchange-mass spectrometry (HDX-MS) is a powerful technique for studying protein dynamics, however its widespread application has been constrained by high sample consumpti...
Double-stranded RNA (dsRNA) is a well-recognized byproduct of in vitro transcription that poses significant challenges for the use of synthetic mRNA in research and therapeutic applications....
At Evotec, we turn great science into real-world medicines; faster, smarter and at exceptional quality. We partner with biotech, pharma and academic institutions to deliver from disease unde...
Brain-derived extracellular vesicle (EV) biomarkers represent a promising frontier for liquid biopsy development targeting the nervous system. They offer strong potential for enabling minima...
Traumatic brain injury, together with adjacent brain conditions such as Alzheimer’s disease, is a global health crisis. In this presentation, Aleksandra Hemm, Product Manager from Ther...
Discover how Novartis and Genedata partnered in the development of a robust, efficient, and user-friendly New Peak Detection (NPD) workflow to facilitate the implementation of the Multi-Attr...
Join us for an expert-led webinar with Adham Ahmed as he delves into the intricacies of developing robust and reliable reversed-phase chromatography methods. This session will cover critical...
The HIV-1 Nef accessory factor promotes viral replication and immune escape of HIV-infected cells, making it an attractive drug target. Our team previously identified small molecules that bi...
The purification of proteins and antibodies is a critical process in biotechnology and pharmaceutical industries. Traditional methods often involve single-use materials, leading to high cost...
Membrane proteins are the gateway to cells and are involved in many critical functions. Each membrane protein is unique, and their complexity makes it difficult to fit into a standardized ex...
Analytical ultracentrifugation is an established method during the development of therapeutic proteins and antibodies and contributes supporting information regarding the size, oligomerizati...
Developing and validating RUO targeted quantitative methods for clinical applications presents many challenges to researchers. Resulting LC-MSn methods cover diverse molecular classes of com...
FEB 04, 2025 | 7:00 AM
C.E. CREDITS
Protein biomarker discovery, validation and utilization require technologies that deliver proteome insights with breadth and depth. Liquid chromatography mass spectrometry (LC-MS), the gold-...
Adeno-associated viruses (AAVs) are as small, replication-defective, non-enveloped viruses, serving as vectors for gene therapy. AAV vectors play a transformative role in delivering therapeu...
The field of ion chromatography (IC) has become indispensable for the analysis of ionic and small polar compounds. Its applications are extensive, ranging from drinking water analysis to foo...
September 19, 2024 | 10 AM EDT, 7AM PDT, 4 PM CEST
The sample throughput of high-sensitivity liquid chromatography-mass spectrometry (LC-MS) proteomics analysis is restricted by the pressure limitations of LC and column hardware, with some m...
As the most widely used viral vector for gene therapies, Adeno-Associated Viruses (AAVs) present unique advantages, including their ability to enter both dividing and non-dividing cells, the...
The recognition of mRNA molecules as a transformative class of therapeutic drugs has soared, particularly with the development of COVID 19 mRNA vaccines. The cancer treatment landscape is si...
APR 03, 2024 | 10:30 AM
C.E. CREDITS
We are leading the way in developing integrated online sampling and Process Analytical Technology (PAT) workflows for quick monitoring of critical quality attributes (CQA) to produce advance...
Today, we are accustomed to updating software on a regular basis. Whether it's our phone's operating system, or our game consoles, we like to keep things up to date with top tier sup...
This talk will focus on doing method validation work in an environment where data is gathered from laboratory information system and chromatography data system. We’ll see how these sys...