Chromatography: an analytical technique commonly used for separating a mixture of chemical substances into its individual components, so that the individual components can be thoroughly analyzed. . The mixture is dissolved in a fluid called the mobile phase, which carries it through a structure holding another material called the stationary phase. The various constituents of the mixture travel at different speeds, causing them to separate. The separation is based on differential partitioning between the mobile and stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus affect the separation.
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Imaged isoelectric focusing (icIEF) has been established as the standard technique for profiling charge heterogeneity, which is a critical quality attribute (CQA) of biotherapeutics....
Advancements in protein and gene therapy research have led to more complex modalities being developed. In addition, the desire for a deeper understanding of these molecules enhances the need...
APR 20, 2023 | 6:00 AM
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The use of Δ8-THC in consumer products has caused safety concerns in the US. Though Δ9-THC is the main intoxicating component in the cannabis plant, its isomer, Δ8-THC, nat...
APR 05, 2023 | 5:30 AM
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In search of the next generation chromatographic technique for antibody purification, our team has developed an affinity chromatography method using the unconventional nucleotide binding sit...
OCT 24, 2022 | 10:00 AM
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Date: October 24, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) The incredible success of mRNA vaccines against COVID-19 has generated a surge of interest and investment in the devel...
Date: September 29, 2022 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CEST) Accurate mass analysis coupled with liquid chromatography is a powerful qualitative and quantitative tool that affor...
Date: September 14, 2022 Time: 8:00am (PDT), 11:00am (EDT), 6:00pm (CEST) Lipid nanoparticles (LNPs) are widely used vehicles for oligonucleotide-based therapeutics and vaccines, which are c...
Date: September 13, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Preparedness against pandemic diseases demands rapid-response vaccine technology and ready-to-use analytical methods...
Date: August 11, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Proteins have long been recognized as novel molecules due to their broad therapeutic applications. However, with the nu...
Date: May 17, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 8:00pm (CEST) Gene therapeutics have great potential to treat many severe diseases in an unprecedented, targeted manner. The biopharmace...
APR 06, 2022 | 11:30 AM
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The vast structural diversity of proteins is responsible for their functional versatility, but also makes their expression and purification a demanding task. Tagging proteins with affinity t...
APR 06, 2022 | 9:00 AM
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There is growing interest in the development of integrated continuous bioprocesses for the production of important biotherapeutics due to the potential for enhanced productivity, greater fle...
MAR 23, 2022 | 11:55 PM
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In-house testing is not required federally; however, states differ in their requirements. Cannabis extraction laboratories need to test extracts for pesticides, heavy metals, residual solven...