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Drug Discovery
Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
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NOV 29, 2018Cannabis Sciences
Clinical trials are a necessary part of the drug approval process. All drugs on the market, even the over-the-counter dr ...Written By: Amy LoriauxNOV 29, 2018Chemistry & Physics
60 years ago in the Brookhaven National Laboratory (BNL), the DOE's cutting-edge nuclear research facility located o ...Written By: Daniel DuanNOV 28, 2018Cannabis Sciences
When Canada legalized recreational marijuana this year, there were celebrations country-wide. Peter Tosh played on in th ...Written By: Amy LoriauxNOV 25, 2018Drug Discovery & Development
A downside to aging is that the skeletal muscles lose their ability to heal after muscle injury. However, a recent resea ...Written By: Nouran AminNOV 25, 2018Drug Discovery & Development
Cases of Cutaneous leishmaniasis (CL), a parasitic disease, has increased dramatically in Syria and neighboring countrie ...Written By: Nouran AminNOV 25, 2018Microbiology
First identified in 1993, hantavirus infections can cause dangerous and potentially deadly respiratory infections.Written By: Carmen LeitchNOV 24, 2018Drug Discovery & Development
For decades, anti-malaria drugs--known as Chloroquines, have used to treat cancer. But the role in repurposing these dru ...Written By: Nouran AminNOV 24, 2018Genetics & Genomics
Our genomic sequence is thought to remain the same throughout our lives. But new research has found evidence to the cont ...Written By: Carmen LeitchNOV 23, 2018Cannabis Sciences
The evidence that the endocannabinoid system (ECS) is intimately involved in food intake has been steadily increasing. T ...Written By: Amy LoriauxNOV 22, 2018Cell & Molecular Biology
Researchers at the University of Minnesota have developed a technique to stop the movement of cancer cells.Written By: Carmen LeitchNOV 22, 2018Chemistry & Physics
Transient Receptor Potential Vanilloid 1 cation channel, or TRPV1, plays an important role in the human body in sensing ...Written By: Daniel DuanNOV 22, 2018Drug Discovery & Development
Tamoxifen is currently a drug used in the treatment of breast cancer, and has been used in patients for many years. Now, ...Written By: Nouran AminNOV 21, 2018Drug Discovery & Development
From a failed pain drug, a protein called ‘BH4’, was recently discovered to have surprising implications in ...Written By: Nouran AminNOV 21, 2018Microbiology
In 1999, there were 62 cases of West Nile Virus in New York State. Since then it has spread around the United States.Written By: Carmen LeitchNOV 21, 2018Cell & Molecular Biology
Organoids are advancing research by providing scientists with a 3D model of a human organ. But are they what they seem?Written By: Carmen LeitchNOV 15, 2018Drug Discovery & Development
At Karolinska Institutet in Sweden, a team of scientists from multiple disciplines have worked together to develop an in ...Written By: Nouran AminNOV 15, 2018Drug Discovery & Development
Neuroblastoma is one of the most common childhood cancers and the leading cause of cancer deaths among pediatric patient ...Written By: Nouran AminNOV 15, 2018Drug Discovery & Development
A common condition of the nervous system, Restless Leg Syndrome (RLS) is the overwhelming urge to move the legs. Usually ...Written By: Nouran AminNOV 15, 2018Drug Discovery & Development
In a publication in Trends in Pharmacological Sciences, a subclass of anti-aging compounds, called geroneuroprotectors ( ...Written By: Nouran AminNOV 13, 2018Cell & Molecular Biology
Cells have a barrier around them, which carefully controls what can move across it. That presents a challenge in pharmac ...Written By: Carmen LeitchNOV 13, 2018Drug Discovery & Development
Niemann-Pick type C (NPC) is a rare and fatal neurodegenerative disease. Symptoms of the condition include loss of balan ...Written By: Nouran AminNOV 12, 2018Cancer
Primary malignant liver tumors are rare in children with an occurrence rate of 1-2% of all childhood cancers. Radical su ...Written By: Heba El-wassefNOV 10, 2018Genetics & Genomics
Directed evolution is a Nobel-prize winning technique that has now been simplified and accelerated.Written By: Carmen LeitchNOV 08, 2018Health & Medicine
The benefits of aspirin use in patients with known cardiovascular disease (CVD) are well-established. A 2015 meta-analys ...Written By: Abbie Arce
NOV 29, 2018
Cannabis Sciences
Clinical trials are a necessary part of the drug approval process. All drugs on the market, even the over-the-counter dr
...
Written By:
Amy Loriaux
NOV 29, 2018
Chemistry & Physics
60 years ago in the Brookhaven National Laboratory (BNL), the DOE's cutting-edge nuclear research facility located o
...
Written By:
Daniel Duan
NOV 28, 2018
Cannabis Sciences
When Canada legalized recreational marijuana this year, there were celebrations country-wide. Peter Tosh played on in th
...
Written By:
Amy Loriaux
NOV 25, 2018
Drug Discovery & Development
A downside to aging is that the skeletal muscles lose their ability to heal after muscle injury. However, a recent resea
...
Written By:
Nouran Amin
NOV 25, 2018
Drug Discovery & Development
Cases of Cutaneous leishmaniasis (CL), a parasitic disease, has increased dramatically in Syria and neighboring countrie
...
Written By:
Nouran Amin
NOV 25, 2018
Microbiology
First identified in 1993, hantavirus infections can cause dangerous and potentially deadly respiratory infections.
Written By:
Carmen Leitch
NOV 24, 2018
Drug Discovery & Development
For decades, anti-malaria drugs--known as Chloroquines, have used to treat cancer. But the role in repurposing these dru
...
Written By:
Nouran Amin
NOV 24, 2018
Genetics & Genomics
Our genomic sequence is thought to remain the same throughout our lives. But new research has found evidence to the cont
...
Written By:
Carmen Leitch
NOV 23, 2018
Cannabis Sciences
The evidence that the endocannabinoid system (ECS) is intimately involved in food intake has been steadily increasing. T
...
Written By:
Amy Loriaux
NOV 22, 2018
Cell & Molecular Biology
Researchers at the University of Minnesota have developed a technique to stop the movement of cancer cells.
Written By:
Carmen Leitch
NOV 22, 2018
Chemistry & Physics
Transient Receptor Potential Vanilloid 1 cation channel, or TRPV1, plays an important role in the human body in sensing
...
Written By:
Daniel Duan
NOV 22, 2018
Drug Discovery & Development
Tamoxifen is currently a drug used in the treatment of breast cancer, and has been used in patients for many years. Now,
...
Written By:
Nouran Amin
NOV 21, 2018
Drug Discovery & Development
From a failed pain drug, a protein called ‘BH4’, was recently discovered to have surprising implications in
...
Written By:
Nouran Amin
NOV 21, 2018
Microbiology
In 1999, there were 62 cases of West Nile Virus in New York State. Since then it has spread around the United States.
Written By:
Carmen Leitch
NOV 21, 2018
Cell & Molecular Biology
Organoids are advancing research by providing scientists with a 3D model of a human organ. But are they what they seem?
Written By:
Carmen Leitch
NOV 15, 2018
Drug Discovery & Development
At Karolinska Institutet in Sweden, a team of scientists from multiple disciplines have worked together to develop an in
...
Written By:
Nouran Amin
NOV 15, 2018
Drug Discovery & Development
Neuroblastoma is one of the most common childhood cancers and the leading cause of cancer deaths among pediatric patient
...
Written By:
Nouran Amin
NOV 15, 2018
Drug Discovery & Development
A common condition of the nervous system, Restless Leg Syndrome (RLS) is the overwhelming urge to move the legs. Usually
...
Written By:
Nouran Amin
NOV 15, 2018
Drug Discovery & Development
In a publication in Trends in Pharmacological Sciences, a subclass of anti-aging compounds, called geroneuroprotectors (
...
Written By:
Nouran Amin
NOV 13, 2018
Cell & Molecular Biology
Cells have a barrier around them, which carefully controls what can move across it. That presents a challenge in pharmac
...
Written By:
Carmen Leitch
NOV 13, 2018
Drug Discovery & Development
Niemann-Pick type C (NPC) is a rare and fatal neurodegenerative disease. Symptoms of the condition include loss of balan
...
Written By:
Nouran Amin
NOV 12, 2018
Cancer
Primary malignant liver tumors are rare in children with an occurrence rate of 1-2% of all childhood cancers. Radical su
...
Written By:
Heba El-wassef
NOV 10, 2018
Genetics & Genomics
Directed evolution is a Nobel-prize winning technique that has now been simplified and accelerated.
Written By:
Carmen Leitch
NOV 08, 2018
Health & Medicine
The benefits of aspirin use in patients with known cardiovascular disease (CVD) are well-established. A 2015 meta-analys
...
Written By:
Abbie Arce