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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • OCT 06, 2018
      Drug Discovery & Development
      New Class of Drugs for Breast Cancer Therapy
      New Class of Drugs for Breast Cancer Therapy
      Scientists at Stevens Institute of Technology have designed a new class of molecules that may hold the potential to add ...
      Written By: Nouran Amin
      2
      OCT 05, 2018
      Cancer
      FDA approves a new drug for an advanced type of skin cancer
      FDA approves a new drug for an advanced type of skin cancer
      As cancer is one of the most challenging diseases in our world, many efforts have been put into researching new ways for ...
      Written By: Heba El-wassef
      1
      OCT 02, 2018
      Drug Discovery & Development
      Compound Found In Fruits and Vegetables May Be The Next Anti-Aging Drug
      Compound Found In Fruits and Vegetables May Be The Next Anti-Aging Drug
      According to early research published in Nature Medicine, it was found possible to increase the longevity of damaged cel ...
      Written By: Nouran Amin
      2
      OCT 02, 2018
      Drug Discovery & Development
      Mycobacterial Lung Disease, FDA Approves New Drug
      Mycobacterial Lung Disease, FDA Approves New Drug
      New drug seeking to treat antibiotic-resistant lung disease has just been approved by the U.S. Food and Drug Administrat ...
      Written By: Nouran Amin
      2
      OCT 02, 2018
      Cell & Molecular Biology
      Approved Drug may Slow the Progression of Alzheimer's
      Approved Drug may Slow the Progression of Alzheimer's
      For many, Alzheimer's disease is just a fact of old age; around 50 percent of people that live to age 85 will get the di ...
      Written By: Carmen Leitch
      1
      OCT 01, 2018
      Cell & Molecular Biology
      Revealing How Antibiotics Work Against Bacteria
      Revealing How Antibiotics Work Against Bacteria
      In a first, researchers have directly observed an antibiotic in action as it disrupted the membrane of a bacterial cell.
      Written By: Carmen Leitch
      1
      SEP 30, 2018
      Drug Discovery & Development
      Vitamin D May Decrease Childhood Obesity
      Vitamin D May Decrease Childhood Obesity
      According to research presented in the in Annual European Society for Pediatric Endocrinology, vitamin D supplements may ...
      Written By: Nouran Amin
      2
      SEP 30, 2018
      Drug Discovery & Development
      Researchers Re-classify the 'Magic Mushroom' Drug
      Researchers Re-classify the 'Magic Mushroom' Drug
      Researchers at John Hopkins have evaluated the safety and efficacy of compound, psilocybin, found in hallucinogenic mush ...
      Written By: Nouran Amin
      2
      SEP 26, 2018
      Microbiology
      Improving Gut Health - with Viruses
      Improving Gut Health - with Viruses
      Viruses don't only infect animals. Some, called bacteriophages, can infect bacteria.
      Written By: Carmen Leitch
      1
      SEP 24, 2018
      Drug Discovery & Development
      Protein Serves as a Potential Drug Target
      Protein Serves as a Potential Drug Target
      Researchers at Van Andel Research Institute (VARI) have shown an atomic-level structure of a protein that may serve as a ...
      Written By: Nouran Amin
      2
      SEP 24, 2018
      Drug Discovery & Development
      Natural Antibiotic Effective for Drug-Resistant Tuberculosis
      Natural Antibiotic Effective for Drug-Resistant Tuberculosis
      A paper published in journal Molecular Cell, describes a naturally occurring antibiotic known as kanglemycin A which is ...
      Written By: Nouran Amin
      2
      SEP 24, 2018
      Drug Discovery & Development
      Pain Management Drug Found Ineffective in Traumatic Injury Patients
      Pain Management Drug Found Ineffective in Traumatic Injury Patients
      Driven by the effort to identify effective non-opioid pain medications, a recent international research study with a pub ...
      Written By: Nouran Amin
      2
      SEP 23, 2018
      Cell & Molecular Biology
      Insulin may be a new Colitis Treatment
      Insulin may be a new Colitis Treatment
      Insulin is a necessary medicine for diabetics, but new work shows that insulin may also be used to treat chronic bowel i ...
      Written By: Carmen Leitch
      1
      SEP 20, 2018
      Drug Discovery & Development
      Chemotherapeutic Drugs Battle Antimalarial Drug Resistance
      Chemotherapeutic Drugs Battle Antimalarial Drug Resistance
      According to the latest research published in the journal Nature Communications, researchers discovered that chemotherap ...
      Written By: Nouran Amin
      2
      SEP 19, 2018
      Cell & Molecular Biology
      A Molecule That Coaxes Muscles to Burn More Fat
      A Molecule That Coaxes Muscles to Burn More Fat
      Scientists have identified an important molecule that is critical to metabolism.
      Written By: Carmen Leitch
      1
      SEP 18, 2018
      Drug Discovery & Development
      Compound Prevents Malaria Transmission in Mosquitoes
      Compound Prevents Malaria Transmission in Mosquitoes
      In a publication in Nature Communications, scientists from the Imperial College London have recently screened 70,000 com ...
      Written By: Nouran Amin
      2
      SEP 18, 2018
      Drug Discovery & Development
      More Challenges in Immunotherapeutic Developments
      More Challenges in Immunotherapeutic Developments
      Fighting disease using the immune system is the body’s most prized possession and it does so by utilizing immunoth ...
      Written By: Nouran Amin
      2
      SEP 15, 2018
      Videos
      A Hangover Cure in a Pill
      A Hangover Cure in a Pill
      A night of drinking can lead to a morning of regret for many people, but science is working on a solution for the physic ...
      Written By: Carmen Leitch
      1
      SEP 11, 2018
      Drug Discovery & Development
      Stimuli-Responsive Nanoparticles as a Drug Delivery Method
      Stimuli-Responsive Nanoparticles as a Drug Delivery Method
      Researchers at Washington State University (WSU), who were finding a way to fight an inflammatory response that causes o ...
      Written By: Nouran Amin
      1
      SEP 11, 2018
      Drug Discovery & Development
      Widely-Used Drug Contributed To Skin Cancer
      Widely-Used Drug Contributed To Skin Cancer
      In a research study at the University of Dundee, Queen Mary University of London and the Wellcome Sanger Institute, a dr ...
      Written By: Nouran Amin
      1
      SEP 11, 2018
      Drug Discovery & Development
      Potential Non-Antibiotic Drug For Tuberculosis
      Potential Non-Antibiotic Drug For Tuberculosis
      After 10 years of research, scientists at the University of Manchester have created the first non-antibiotic drug that c ...
      Written By: Nouran Amin
      1 1
      SEP 08, 2018
      Drug Discovery & Development
      Protein Associated With ALS Inspires Drug Treatments
      Protein Associated With ALS Inspires Drug Treatments
      Neurodegenerative diseases, such as degenerative ataxia or amyotrophic lateral sclerosis (ALS), will progressively cause ...
      Written By: Nouran Amin
      1
      SEP 07, 2018
      Videos
      The Therapeutic Potential of Venoms
      The Therapeutic Potential of Venoms
      Over 220,000 species, around 15 percent of the world's described animals, are known to be venomous.
      Written By: Carmen Leitch
      2
      SEP 05, 2018
      Clinical & Molecular DX
      Iron-based MRI Contrast Outperforms Less Safe Method
      Iron-based MRI Contrast Outperforms Less Safe Method
      A new method for loading iron inside nanoparticles creates MRI contrast agents that work better than the mainstay gadoli ...
      Written By: Futurity (futurity.org)
      1
    OCT 06, 2018
    Drug Discovery & Development
    New Class of Drugs for Breast Cancer Therapy
    New Class of Drugs for Breast Cancer Therapy
    Scientists at Stevens Institute of Technology have designed a new class of molecules that may hold the potential to add ...
    Written By: Nouran Amin
    2
    OCT 05, 2018
    Cancer
    FDA approves a new drug for an advanced type of skin cancer
    FDA approves a new drug for an advanced type of skin cancer
    As cancer is one of the most challenging diseases in our world, many efforts have been put into researching new ways for ...
    Written By: Heba El-wassef
    1
    OCT 02, 2018
    Drug Discovery & Development
    Compound Found In Fruits and Vegetables May Be The Next Anti-Aging Drug
    Compound Found In Fruits and Vegetables May Be The Next Anti-Aging Drug
    According to early research published in Nature Medicine, it was found possible to increase the longevity of damaged cel ...
    Written By: Nouran Amin
    2
    OCT 02, 2018
    Drug Discovery & Development
    Mycobacterial Lung Disease, FDA Approves New Drug
    Mycobacterial Lung Disease, FDA Approves New Drug
    New drug seeking to treat antibiotic-resistant lung disease has just been approved by the U.S. Food and Drug Administrat ...
    Written By: Nouran Amin
    2
    OCT 02, 2018
    Cell & Molecular Biology
    Approved Drug may Slow the Progression of Alzheimer's
    Approved Drug may Slow the Progression of Alzheimer's
    For many, Alzheimer's disease is just a fact of old age; around 50 percent of people that live to age 85 will get the di ...
    Written By: Carmen Leitch
    1
     
     
  • OCT 01, 2018
    Cell & Molecular Biology
    Revealing How Antibiotics Work Against Bacteria
    Revealing How Antibiotics Work Against Bacteria
    In a first, researchers have directly observed an antibiotic in action as it disrupted the membrane of a bacterial cell.
    Written By: Carmen Leitch
    1
    SEP 30, 2018
    Drug Discovery & Development
    Vitamin D May Decrease Childhood Obesity
    Vitamin D May Decrease Childhood Obesity
    According to research presented in the in Annual European Society for Pediatric Endocrinology, vitamin D supplements may ...
    Written By: Nouran Amin
    2
    SEP 30, 2018
    Drug Discovery & Development
    Researchers Re-classify the 'Magic Mushroom' Drug
    Researchers Re-classify the 'Magic Mushroom' Drug
    Researchers at John Hopkins have evaluated the safety and efficacy of compound, psilocybin, found in hallucinogenic mush ...
    Written By: Nouran Amin
    2
    SEP 26, 2018
    Microbiology
    Improving Gut Health - with Viruses
    Improving Gut Health - with Viruses
    Viruses don't only infect animals. Some, called bacteriophages, can infect bacteria.
    Written By: Carmen Leitch
    1
    SEP 24, 2018
    Drug Discovery & Development
    Protein Serves as a Potential Drug Target
    Protein Serves as a Potential Drug Target
    Researchers at Van Andel Research Institute (VARI) have shown an atomic-level structure of a protein that may serve as a ...
    Written By: Nouran Amin
    2
     
     
  • SEP 24, 2018
    Drug Discovery & Development
    Natural Antibiotic Effective for Drug-Resistant Tuberculosis
    Natural Antibiotic Effective for Drug-Resistant Tuberculosis
    A paper published in journal Molecular Cell, describes a naturally occurring antibiotic known as kanglemycin A which is ...
    Written By: Nouran Amin
    2
    SEP 24, 2018
    Drug Discovery & Development
    Pain Management Drug Found Ineffective in Traumatic Injury Patients
    Pain Management Drug Found Ineffective in Traumatic Injury Patients
    Driven by the effort to identify effective non-opioid pain medications, a recent international research study with a pub ...
    Written By: Nouran Amin
    2
    SEP 23, 2018
    Cell & Molecular Biology
    Insulin may be a new Colitis Treatment
    Insulin may be a new Colitis Treatment
    Insulin is a necessary medicine for diabetics, but new work shows that insulin may also be used to treat chronic bowel i ...
    Written By: Carmen Leitch
    1
    SEP 20, 2018
    Drug Discovery & Development
    Chemotherapeutic Drugs Battle Antimalarial Drug Resistance
    Chemotherapeutic Drugs Battle Antimalarial Drug Resistance
    According to the latest research published in the journal Nature Communications, researchers discovered that chemotherap ...
    Written By: Nouran Amin
    2
    SEP 19, 2018
    Cell & Molecular Biology
    A Molecule That Coaxes Muscles to Burn More Fat
    A Molecule That Coaxes Muscles to Burn More Fat
    Scientists have identified an important molecule that is critical to metabolism.
    Written By: Carmen Leitch
    1
     
     
  • SEP 18, 2018
    Drug Discovery & Development
    Compound Prevents Malaria Transmission in Mosquitoes
    Compound Prevents Malaria Transmission in Mosquitoes
    In a publication in Nature Communications, scientists from the Imperial College London have recently screened 70,000 com ...
    Written By: Nouran Amin
    2
    SEP 18, 2018
    Drug Discovery & Development
    More Challenges in Immunotherapeutic Developments
    More Challenges in Immunotherapeutic Developments
    Fighting disease using the immune system is the body’s most prized possession and it does so by utilizing immunoth ...
    Written By: Nouran Amin
    2
    SEP 15, 2018
    Videos
    A Hangover Cure in a Pill
    A Hangover Cure in a Pill
    A night of drinking can lead to a morning of regret for many people, but science is working on a solution for the physic ...
    Written By: Carmen Leitch
    1
    SEP 11, 2018
    Drug Discovery & Development
    Stimuli-Responsive Nanoparticles as a Drug Delivery Method
    Stimuli-Responsive Nanoparticles as a Drug Delivery Method
    Researchers at Washington State University (WSU), who were finding a way to fight an inflammatory response that causes o ...
    Written By: Nouran Amin
    1
    SEP 11, 2018
    Drug Discovery & Development
    Widely-Used Drug Contributed To Skin Cancer
    Widely-Used Drug Contributed To Skin Cancer
    In a research study at the University of Dundee, Queen Mary University of London and the Wellcome Sanger Institute, a dr ...
    Written By: Nouran Amin
    1
     
     
  • SEP 11, 2018
    Drug Discovery & Development
    Potential Non-Antibiotic Drug For Tuberculosis
    Potential Non-Antibiotic Drug For Tuberculosis
    After 10 years of research, scientists at the University of Manchester have created the first non-antibiotic drug that c ...
    Written By: Nouran Amin
    1 1
    SEP 08, 2018
    Drug Discovery & Development
    Protein Associated With ALS Inspires Drug Treatments
    Protein Associated With ALS Inspires Drug Treatments
    Neurodegenerative diseases, such as degenerative ataxia or amyotrophic lateral sclerosis (ALS), will progressively cause ...
    Written By: Nouran Amin
    1
    SEP 07, 2018
    Videos
    The Therapeutic Potential of Venoms
    The Therapeutic Potential of Venoms
    Over 220,000 species, around 15 percent of the world's described animals, are known to be venomous.
    Written By: Carmen Leitch
    2
    SEP 05, 2018
    Clinical & Molecular DX
    Iron-based MRI Contrast Outperforms Less Safe Method
    Iron-based MRI Contrast Outperforms Less Safe Method
    A new method for loading iron inside nanoparticles creates MRI contrast agents that work better than the mainstay gadoli ...
    Written By: Futurity (futurity.org)
    1
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