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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • AUG 15, 2018
      Drug Discovery & Development
      Experimental Drug May Treat The Chronic Itch
      Experimental Drug May Treat The Chronic Itch
      Investigators at the University of Zurich have discovered a new approach that treats the chronic itch thanks to two rece ...
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      1
      AUG 15, 2018
      Drug Discovery & Development
      Peripheral Nerve Blockers Treat Facial Pain
      Peripheral Nerve Blockers Treat Facial Pain
      A new research study published American Journal of Emergency Medicine explains the use of peripheral nerve inhibitors in ...
      Written By: Nouran Amin
      1
      AUG 14, 2018
      Drug Discovery & Development
      Single Antiplatelet Drug Reduces Risk of Blood Clots
      Single Antiplatelet Drug Reduces Risk of Blood Clots
      According to the current treatment protocol, patients that undergo minimally invasive aortic heart valve replacements wi ...
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      AUG 14, 2018
      Cancer
      New Drug for Refractory Cutaneous T-cell Lymphoma
      New Drug for Refractory Cutaneous T-cell Lymphoma
      Mogamulizumab was approved by the FDA this month after a very successful Phase III clinical trial demonstrating its effe ...
      Written By: Mauri Brueggeman
      1
      AUG 14, 2018
      Drug Discovery & Development
      Anticancer Drugs Help Plants Fight Infection
      Anticancer Drugs Help Plants Fight Infection
      Drugs used for cancer treatments may now help plants fight diseases. A study conducted at Washington State University (W ...
      Written By: Nouran Amin
      1
      AUG 14, 2018
      Cell & Molecular Biology
      A Totally New Look at the Cell's Powerhouse
      A Totally New Look at the Cell's Powerhouse
      Mitochondria don't only have their own DNA. They also have their own ribosomes.
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      1
      AUG 14, 2018
      Microbiology
      How Ebola Gets Into Cells
      How Ebola Gets Into Cells
      Researchers have learned how Ebola gains entry to cells, which can help us stop it.
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      AUG 10, 2018
      Immunology
      Cancer Cell 'Drones' Battle Immune System
      Cancer Cell 'Drones' Battle Immune System
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      AUG 08, 2018
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      1
      AUG 08, 2018
      Drug Discovery & Development
      Cholesterol Pill For Treating A Brutal Lung Disease
      Cholesterol Pill For Treating A Brutal Lung Disease
      A brutal lung disease called Pulmonary Alveolar Proteinosis (PAP) is caused by a thick substance known as surfactant tha ...
      Written By: Nouran Amin
      2
      AUG 08, 2018
      Drug Discovery & Development
      Injection Improves Corneal Transplant Outcomes
      Injection Improves Corneal Transplant Outcomes
      The common form of tissue transplant is the corneal transplant. Corneal transplantation is performed to correct visual l ...
      Written By: Nouran Amin
      1
      AUG 08, 2018
      Drug Discovery & Development
      Old Drug Offers Novel Treatment For Hair Loss
      Old Drug Offers Novel Treatment For Hair Loss
      According to researchers from The University of Manchester's Centre for Dermatology Research, a recent developed dru ...
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      1
      AUG 07, 2018
      Drug Discovery & Development
      Improving Liver Cancer Therapy
      Improving Liver Cancer Therapy
      According to studies conducted in the United States, the ninth leading causes of cancer deaths is hepatocellular carcino ...
      Written By: Nouran Amin
      1
      AUG 04, 2018
      Technology
      AI Designs Drugs From Scratch
      AI Designs Drugs From Scratch
      Artificial Intelligence (AI) has demonstrated unique qualities in the past decade. Recent research has used AI to furthe ...
      Written By: Nouran Amin
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      AUG 02, 2018
      Videos
      Which is More Damaging to Your Health, Alcohol or Weed?
      Which is More Damaging to Your Health, Alcohol or Weed?
      Marijuana is classified as a Schedule 1 drug under the federal government, making it a challenger for scientists to cond ...
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      AUG 01, 2018
      Cell & Molecular Biology
      Levels of One Molecule, LAC, can Diagnose Depression
      Levels of One Molecule, LAC, can Diagnose Depression
      Depression can be hard to classify and therefore, challenging to treat. New work could help change that.
      Written By: Carmen Leitch
      1
      AUG 01, 2018
      Drug Discovery & Development
      Effective Drug For Disorders of Copper Metabolism
      Effective Drug For Disorders of Copper Metabolism
      According to a paper in the Proceedings of the National Academy of Sciences, a research team led by Dr. Vishal Gohil of ...
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      JUL 31, 2018
      Drug Discovery & Development
      DNA For Drug Development?
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      JUL 31, 2018
      Drug Discovery & Development
      Pill Approved For Endometriosis Treatment
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      A first drug, by the name of Elagolix, to treat for endometriosis-related pain, has recently become approved by the US F ...
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      1
      JUL 31, 2018
      Drug Discovery & Development
      Two Molecules Identified For Treating Traumatic Brain Injury (TBI)
      Two Molecules Identified For Treating Traumatic Brain Injury (TBI)
      Scientists at Rutgers University have discovered two molecules that protect nerve cells, serving as motivation to develo ...
      Written By: Nouran Amin
      1
      JUL 30, 2018
      Genetics & Genomics
      Therapeutic Created for a Rare Genetic Disease
      Therapeutic Created for a Rare Genetic Disease
      There is new hope for people that suffer from a rare genetic disease called Hereditary angioedema (HAE).
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      1
      JUL 29, 2018
      Microbiology
      Revealing why Sepsis Causes Organs to Fail
      Revealing why Sepsis Causes Organs to Fail
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      JUL 28, 2018
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      23andMe Announces Partnership with Drug Company GSK
      The collaboration aims to improve personalized therapeutics.
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      1
      JUL 25, 2018
      Videos
      What the Cockroach Genome can Teach us
      What the Cockroach Genome can Teach us
      The genome of the cockroach was recently sequenced, and scientists have gained some insight into why they are so tough.
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    AUG 15, 2018
    Drug Discovery & Development
    Experimental Drug May Treat The Chronic Itch
    Experimental Drug May Treat The Chronic Itch
    Investigators at the University of Zurich have discovered a new approach that treats the chronic itch thanks to two rece ...
    Written By: Nouran Amin
    1
    AUG 15, 2018
    Drug Discovery & Development
    Peripheral Nerve Blockers Treat Facial Pain
    Peripheral Nerve Blockers Treat Facial Pain
    A new research study published American Journal of Emergency Medicine explains the use of peripheral nerve inhibitors in ...
    Written By: Nouran Amin
    1
    AUG 14, 2018
    Drug Discovery & Development
    Single Antiplatelet Drug Reduces Risk of Blood Clots
    Single Antiplatelet Drug Reduces Risk of Blood Clots
    According to the current treatment protocol, patients that undergo minimally invasive aortic heart valve replacements wi ...
    Written By: Nouran Amin
    1
    AUG 14, 2018
    Cancer
    New Drug for Refractory Cutaneous T-cell Lymphoma
    New Drug for Refractory Cutaneous T-cell Lymphoma
    Mogamulizumab was approved by the FDA this month after a very successful Phase III clinical trial demonstrating its effe ...
    Written By: Mauri Brueggeman
    1
    AUG 14, 2018
    Drug Discovery & Development
    Anticancer Drugs Help Plants Fight Infection
    Anticancer Drugs Help Plants Fight Infection
    Drugs used for cancer treatments may now help plants fight diseases. A study conducted at Washington State University (W ...
    Written By: Nouran Amin
    1
     
     
  • AUG 14, 2018
    Cell & Molecular Biology
    A Totally New Look at the Cell's Powerhouse
    A Totally New Look at the Cell's Powerhouse
    Mitochondria don't only have their own DNA. They also have their own ribosomes.
    Written By: Carmen Leitch
    1
    AUG 14, 2018
    Microbiology
    How Ebola Gets Into Cells
    How Ebola Gets Into Cells
    Researchers have learned how Ebola gains entry to cells, which can help us stop it.
    Written By: Carmen Leitch
    2
    AUG 10, 2018
    Immunology
    Cancer Cell 'Drones' Battle Immune System
    Cancer Cell 'Drones' Battle Immune System
    Cancer cells release PD-L1 containing exosomes that circulate in the blood and stop T cells before they can reach tumors ...
    Written By: Caitlin Williams
    1
    AUG 08, 2018
    Videos
    A Harbinger of Hope for Alzheimer's Patients?
    A Harbinger of Hope for Alzheimer's Patients?
    The search for effective treatments for Alzheimer’s disease is ongoing, but overall, hasn’t been productive. ...
    Written By: Brenda Kelley Kim
    1
    AUG 08, 2018
    Drug Discovery & Development
    Cholesterol Pill For Treating A Brutal Lung Disease
    Cholesterol Pill For Treating A Brutal Lung Disease
    A brutal lung disease called Pulmonary Alveolar Proteinosis (PAP) is caused by a thick substance known as surfactant tha ...
    Written By: Nouran Amin
    2
     
     
  • AUG 08, 2018
    Drug Discovery & Development
    Injection Improves Corneal Transplant Outcomes
    Injection Improves Corneal Transplant Outcomes
    The common form of tissue transplant is the corneal transplant. Corneal transplantation is performed to correct visual l ...
    Written By: Nouran Amin
    1
    AUG 08, 2018
    Drug Discovery & Development
    Old Drug Offers Novel Treatment For Hair Loss
    Old Drug Offers Novel Treatment For Hair Loss
    According to researchers from The University of Manchester's Centre for Dermatology Research, a recent developed dru ...
    Written By: Nouran Amin
    1
    AUG 07, 2018
    Drug Discovery & Development
    Improving Liver Cancer Therapy
    Improving Liver Cancer Therapy
    According to studies conducted in the United States, the ninth leading causes of cancer deaths is hepatocellular carcino ...
    Written By: Nouran Amin
    1
    AUG 04, 2018
    Technology
    AI Designs Drugs From Scratch
    AI Designs Drugs From Scratch
    Artificial Intelligence (AI) has demonstrated unique qualities in the past decade. Recent research has used AI to furthe ...
    Written By: Nouran Amin
    1
    AUG 02, 2018
    Videos
    Which is More Damaging to Your Health, Alcohol or Weed?
    Which is More Damaging to Your Health, Alcohol or Weed?
    Marijuana is classified as a Schedule 1 drug under the federal government, making it a challenger for scientists to cond ...
    Written By: Amanda Kahl
    1
     
     
  • AUG 01, 2018
    Cell & Molecular Biology
    Levels of One Molecule, LAC, can Diagnose Depression
    Levels of One Molecule, LAC, can Diagnose Depression
    Depression can be hard to classify and therefore, challenging to treat. New work could help change that.
    Written By: Carmen Leitch
    1
    AUG 01, 2018
    Drug Discovery & Development
    Effective Drug For Disorders of Copper Metabolism
    Effective Drug For Disorders of Copper Metabolism
    According to a paper in the Proceedings of the National Academy of Sciences, a research team led by Dr. Vishal Gohil of ...
    Written By: Nouran Amin
    1
    JUL 31, 2018
    Drug Discovery & Development
    DNA For Drug Development?
    DNA For Drug Development?
    Genetic data of individuals who were customers of DNA testing service for the purpose of understanding their ancestry an ...
    Written By: Nouran Amin
    1
    JUL 31, 2018
    Drug Discovery & Development
    Pill Approved For Endometriosis Treatment
    Pill Approved For Endometriosis Treatment
    A first drug, by the name of Elagolix, to treat for endometriosis-related pain, has recently become approved by the US F ...
    Written By: Nouran Amin
    1
    JUL 31, 2018
    Drug Discovery & Development
    Two Molecules Identified For Treating Traumatic Brain Injury (TBI)
    Two Molecules Identified For Treating Traumatic Brain Injury (TBI)
    Scientists at Rutgers University have discovered two molecules that protect nerve cells, serving as motivation to develo ...
    Written By: Nouran Amin
    1
     
     
  • JUL 30, 2018
    Genetics & Genomics
    Therapeutic Created for a Rare Genetic Disease
    Therapeutic Created for a Rare Genetic Disease
    There is new hope for people that suffer from a rare genetic disease called Hereditary angioedema (HAE).
    Written By: Carmen Leitch
    1
    JUL 29, 2018
    Microbiology
    Revealing why Sepsis Causes Organs to Fail
    Revealing why Sepsis Causes Organs to Fail
    The Staphylococcus aureus bacterium can cause devastating illnesses - called staph infections - and lead to organ failur ...
    Written By: Carmen Leitch
    2
    JUL 28, 2018
    Videos
    23andMe Announces Partnership with Drug Company GSK
    23andMe Announces Partnership with Drug Company GSK
    The collaboration aims to improve personalized therapeutics.
    Written By: Carmen Leitch
    1
    JUL 25, 2018
    Videos
    What the Cockroach Genome can Teach us
    What the Cockroach Genome can Teach us
    The genome of the cockroach was recently sequenced, and scientists have gained some insight into why they are so tough.
    Written By: Carmen Leitch
    2
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