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Drug Discovery
Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
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APR 13, 2015Cell & Molecular Biology
A new device developed by UCLA engineers and doctors may eventually help scientists study the development of disease, en ...Written By: Ilene SchneiderAPR 13, 2015Cancer
A new study by researchers at the Technion-Israel Institute of Technology could hold a key to control cancer cell growth ...Written By: Will HectorAPR 09, 2015Genetics & Genomics
In a first study to test a new generation of HIV antibodies in humans, an experimental therapy lowered the virus amount ...Written By: Ilene SchneiderAPR 09, 2015Cannabis Sciences
If you want the benefits of medical marijuana without the "unwanted side effects" of cannabis, new research could leave ...Written By: Judy O'RourkeAPR 08, 2015Immunology
An over-the-counter drug indicated to treat allergy symptoms limited hepatitis C virus activity in infected mice, accord ...Written By: Will HectorAPR 07, 2015Neuroscience
A University of Victoria neuroscientist has discovered that a cancer drug may improve recovery rates for diabetic patien ...Written By: Ilene SchneiderAPR 07, 2015Cancer
Biopharmaceutical firm Berg is joining forces with two prominent Harvard-affiliated medical research institutions, the P ...Written By: Ilene SchneiderAPR 06, 2015Cancer
Personalized melanoma vaccines can be used to marshal a powerful immune response against unique mutations in patients' t ...Written By: Ilene SchneiderAPR 06, 2015Cancer
Most of today's anticancer drugs target the DNA or proteins in tumor cells, but a new discovery by University of Califor ...Written By: Robert WoodardAPR 02, 2015Genetics & Genomics
As a patient prepares to become the first in history to receive his own genetically engineered stem cells for sickle cel ...Written By: Ilene SchneiderAPR 01, 2015Genetics & Genomics
Lung diseases like emphysema and pulmonary fibrosis are common among people with malfunctioning telomeres, the "caps" or ...Written By: Ilene SchneiderAPR 01, 2015Cancer
A drug used for decades to treat leukemia may have other uses in the fight against cancer, researchers at the University ...Written By: Ilene SchneiderMAR 30, 2015Cancer
Nearly 50 years after the "war on cancer" was declared in the United States, precision medicine presages an era of incre ...Written By: Ilene SchneiderMAR 26, 2015Genetics & Genomics
deCODE genetics, Reykjavik, Iceland, a global leader in analyzing and understanding the human genome and wholly-owned su ...Written By: Judy O'RourkeMAR 25, 2015Cardiology
Working with lab animals and human heart cells, scientists from Johns Hopkins and other institutions have identified wha ...Written By: Judy O'RourkeMAR 19, 2015Genetics & Genomics
A clinical trial of the most common sickle cell anemia drug, hydroxyurea, was halted a year early this winter because of ...Written By: Ilene SchneiderMAR 18, 2015Neuroscience
Scientists at The University of Manchester have made an important new discovery about the brain's immune system that cou ...Written By: Ilene SchneiderMAR 18, 2015Genetics & Genomics
The largest genetic study of tuberculosis (TB) susceptibility to date has led to a potentially important new insight int ...Written By: Ilene SchneiderMAR 13, 2015Neuroscience
Queensland scientists have found that non-invasive ultrasound technology can be used to treat Alzheimer's disease and re ...Written By: Ilene SchneiderMAR 13, 2015Chemistry & Physics
A new molecule-making machine could do for chemistry what 3-D printing did for engineering: Make it fast, flexible, and ...Written By: Judy O'RourkeMAR 10, 2015Genetics & Genomics
Stephanie Dutchen, Harvard Medical School
It's been "known" for decades: Sensory, motor and cognitive signals ...Written By: Ilene SchneiderMAR 04, 2015Cell & Molecular Biology
Evolution brings improvements, but it's also a hotbed for lots of diseases that defy treatment.
We see this i ...Written By: Judy O'RourkeFEB 26, 2015Microbiology
Researchers at the University of Georgia have identified a previously unknown process that many bacteria, including thos ...Written By: Judy O'RourkeFEB 25, 2015Cell & Molecular Biology
Scientists have shown that small molecules can "hijack" enzyme function in mice, suggesting a possible preventive mechan ...Written By: Ilene Schneider
APR 13, 2015
Cell & Molecular Biology
A new device developed by UCLA engineers and doctors may eventually help scientists study the development of disease, en
...
Written By:
Ilene Schneider
APR 13, 2015
Cancer
A new study by researchers at the Technion-Israel Institute of Technology could hold a key to control cancer cell growth
...
Written By:
Will Hector
APR 09, 2015
Genetics & Genomics
In a first study to test a new generation of HIV antibodies in humans, an experimental therapy lowered the virus amount
...
Written By:
Ilene Schneider
APR 09, 2015
Cannabis Sciences
If you want the benefits of medical marijuana without the "unwanted side effects" of cannabis, new research could leave
...
Written By:
Judy O'Rourke
APR 08, 2015
Immunology
An over-the-counter drug indicated to treat allergy symptoms limited hepatitis C virus activity in infected mice, accord
...
Written By:
Will Hector
APR 07, 2015
Neuroscience
A University of Victoria neuroscientist has discovered that a cancer drug may improve recovery rates for diabetic patien
...
Written By:
Ilene Schneider
APR 07, 2015
Cancer
Biopharmaceutical firm Berg is joining forces with two prominent Harvard-affiliated medical research institutions, the P
...
Written By:
Ilene Schneider
APR 06, 2015
Cancer
Personalized melanoma vaccines can be used to marshal a powerful immune response against unique mutations in patients' t
...
Written By:
Ilene Schneider
APR 06, 2015
Cancer
Most of today's anticancer drugs target the DNA or proteins in tumor cells, but a new discovery by University of Califor
...
Written By:
Robert Woodard
APR 02, 2015
Genetics & Genomics
As a patient prepares to become the first in history to receive his own genetically engineered stem cells for sickle cel
...
Written By:
Ilene Schneider
APR 01, 2015
Genetics & Genomics
Lung diseases like emphysema and pulmonary fibrosis are common among people with malfunctioning telomeres, the "caps" or
...
Written By:
Ilene Schneider
APR 01, 2015
Cancer
A drug used for decades to treat leukemia may have other uses in the fight against cancer, researchers at the University
...
Written By:
Ilene Schneider
MAR 30, 2015
Cancer
Nearly 50 years after the "war on cancer" was declared in the United States, precision medicine presages an era of incre
...
Written By:
Ilene Schneider
MAR 26, 2015
Genetics & Genomics
deCODE genetics, Reykjavik, Iceland, a global leader in analyzing and understanding the human genome and wholly-owned su
...
Written By:
Judy O'Rourke
MAR 25, 2015
Cardiology
Working with lab animals and human heart cells, scientists from Johns Hopkins and other institutions have identified wha
...
Written By:
Judy O'Rourke
MAR 19, 2015
Genetics & Genomics
A clinical trial of the most common sickle cell anemia drug, hydroxyurea, was halted a year early this winter because of
...
Written By:
Ilene Schneider
MAR 18, 2015
Neuroscience
Scientists at The University of Manchester have made an important new discovery about the brain's immune system that cou
...
Written By:
Ilene Schneider
MAR 18, 2015
Genetics & Genomics
The largest genetic study of tuberculosis (TB) susceptibility to date has led to a potentially important new insight int
...
Written By:
Ilene Schneider
MAR 13, 2015
Neuroscience
Queensland scientists have found that non-invasive ultrasound technology can be used to treat Alzheimer's disease and re
...
Written By:
Ilene Schneider
MAR 13, 2015
Chemistry & Physics
A new molecule-making machine could do for chemistry what 3-D printing did for engineering: Make it fast, flexible, and
...
Written By:
Judy O'Rourke
MAR 10, 2015
Genetics & Genomics
Stephanie Dutchen, Harvard Medical School
It's been "known" for decades: Sensory, motor and cognitive signals ...
It's been "known" for decades: Sensory, motor and cognitive signals ...
Written By:
Ilene Schneider
MAR 04, 2015
Cell & Molecular Biology
Evolution brings improvements, but it's also a hotbed for lots of diseases that defy treatment.
We see this i ...
We see this i ...
Written By:
Judy O'Rourke
FEB 26, 2015
Microbiology
Researchers at the University of Georgia have identified a previously unknown process that many bacteria, including thos
...
Written By:
Judy O'Rourke
FEB 25, 2015
Cell & Molecular Biology
Scientists have shown that small molecules can "hijack" enzyme function in mice, suggesting a possible preventive mechan
...
Written By:
Ilene Schneider