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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • MAY 19, 2020
      Drug Discovery & Development
      COVID-19 Vaccine On Track for Late 2020
      COVID-19 Vaccine On Track for Late 2020
      Moderna, a biotechnology company based in Massachusetts, has released information on its vaccine against COVID-19 from i ...
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      MAY 18, 2020
      Cancer
      How do Ohnologs affect Cancer?
      How do Ohnologs affect Cancer?
      Genetics can be complicated to say the least. Sometimes it can be as simple as a single mutation in one gene that causes ...
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      MAY 17, 2020
      Cell & Molecular Biology
      Potential Treatment for Brain and Spinal Cord Injury is IDed
      Potential Treatment for Brain and Spinal Cord Injury is IDed
      Treatment options are limited for people that have suffered swelling-inducing injuries to their brain and spinal cord. N ...
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      MAY 16, 2020
      Neuroscience
      Stem Cell Method (Parkinson's) Could Avoid Transplant Rejection
      Stem Cell Method (Parkinson's) Could Avoid Transplant Rejection
      Researchers at McLean Hospital and Massachusetts General Hospital (MGH) have tested a stem cell treatment method that av ...
      Written By: Amanda Mikyska
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      MAY 16, 2020
      Cannabis Sciences
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      Body's Own Cannabis Helps Us Forget Traumatic Events
      Researchers have found that anandamide, often referred to as the body’s own cannabis, may help us forget traumatic ...
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      MAY 16, 2020
      Cancer
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      Red Blood Cells: More than just an Oxygen Delivery Service
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      2
      MAY 14, 2020
      Drug Discovery & Development
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      MAY 14, 2020
      Cancer
      New hope for immunotherapy for pediatric brain cancer
      New hope for immunotherapy for pediatric brain cancer
      Pediatric brain cancer is an especially tough pill to swallow. While one in four children does not survive medulloblasto ...
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      MAY 14, 2020
      Immunology
      Antibody-laden Nanoparticles to Help COVID Patients Breathe Easy
      Antibody-laden Nanoparticles to Help COVID Patients Breathe Easy
      Antibodies are a powerful countermeasure against COVID-19. Not only can they relieve symptoms in patients experiencing s ...
      Written By: Tara Fernandes
      1
      MAY 13, 2020
      Drug Discovery & Development
      Approved Treatment for RET-mutant Cancers
      Approved Treatment for RET-mutant Cancers
      A drug was recently approved for treating three types of RET-mutant cancers: 1) non-small cell lung cancer (NSCLC) 2) ad ...
      Written By: Nouran Amin
      1
      MAY 13, 2020
      Drug Discovery & Development
      Drug Targets Off Episodes of Parkinson
      Drug Targets Off Episodes of Parkinson
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      MAY 13, 2020
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      Fecal Transplant Helps Fight off Antibiotic Resistance
      Fecal Transplant Helps Fight off Antibiotic Resistance
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      MAY 13, 2020
      Drug Discovery & Development
      FDA Fast Tracks Vaccine for COVID-19
      FDA Fast Tracks Vaccine for COVID-19
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      2
      MAY 12, 2020
      Drug Discovery & Development
      Novel Drug Approved for Non-Small Cell Lung Cancer
      Novel Drug Approved for Non-Small Cell Lung Cancer
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      MAY 12, 2020
      Cannabis Sciences
      Study Shows Cannabis May Block COVID-19 Infection
      Study Shows Cannabis May Block COVID-19 Infection
      Researchers from the University of Lethbridge, Canada, have found that cannabis may be able to block COVID-19 infections ...
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      MAY 12, 2020
      Drug Discovery & Development
      Does Herbal Drink from Madagascar Cure COVID-19?
      Does Herbal Drink from Madagascar Cure COVID-19?
      Andry Rajoelina, the president of Madagascar, an island off the coast of Southern Africa, has made claims that his count ...
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      MAY 12, 2020
      Immunology
      Disabling Genes in Immune Cells Prevents Obesity
      Disabling Genes in Immune Cells Prevents Obesity
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      MAY 11, 2020
      Cancer
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      Using Deep Learning to Diagnose Breast Cancer Sub-Types
      Cancer and computer programming may not sound like two things that go together. However, advanced programming techniques ...
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      MAY 10, 2020
      Drug Discovery & Development
      Antiviral Drug Treats Naso-Pharyngeal Cancer
      Antiviral Drug Treats Naso-Pharyngeal Cancer
      Scientists at Hong Kong Baptist University (HKBU) developed a novel anti-Epstein-Barr virus (EBV) drug that can shrink t ...
      Written By: Nouran Amin
      1
      MAY 09, 2020
      Cancer
      Examining a Combination Therapy Against Gastric Cancer
      Examining a Combination Therapy Against Gastric Cancer
      Often when it comes to treatments for cancer, designing or discovering new leads can take years. One of the common pract ...
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      2
      MAY 08, 2020
      Drug Discovery & Development
      Cholesterol Drugs May Boost Healthy Gut Bacteria in Obese People
      Cholesterol Drugs May Boost Healthy Gut Bacteria in Obese People
      While statins have long been known for their efficacy in treating high cholesterol, until recently, there was no evidenc ...
      Written By: Annie Lennon
      1
      MAY 07, 2020
      Immunology
      New COVID-19 Vaccine Defends Monkeys Against Infection
      New COVID-19 Vaccine Defends Monkeys Against Infection
      Researchers from Beijing-based Sinovac Biotech have reported preliminary results of a study into the development of a va ...
      Written By: Tara Fernandes
      2
      MAY 06, 2020
      Cancer
      Olanzapine useful for cancer patients managing nausea unrelated to chemo
      Olanzapine useful for cancer patients managing nausea unrelated to chemo
      A study published last week in JAMA Oncology reports that a generic drug called Olanzapine could be useful for cancer pa ...
      Written By: Kathryn DeMuth Sullivan
      2
      MAY 06, 2020
      Drug Discovery & Development
      Why Doctors are Repurposing Drugs to Treat COVID-19
      Why Doctors are Repurposing Drugs to Treat COVID-19
      Creating a drug from scratch is a lengthy process. Often taking years, given the rate of infection and deadliness of COV ...
      Written By: Annie Lennon
      1
    MAY 19, 2020
    Drug Discovery & Development
    COVID-19 Vaccine On Track for Late 2020
    COVID-19 Vaccine On Track for Late 2020
    Moderna, a biotechnology company based in Massachusetts, has released information on its vaccine against COVID-19 from i ...
    Written By: Annie Lennon
    2
    MAY 18, 2020
    Cancer
    How do Ohnologs affect Cancer?
    How do Ohnologs affect Cancer?
    Genetics can be complicated to say the least. Sometimes it can be as simple as a single mutation in one gene that causes ...
    Written By: Jasper Cantrell
    1
    MAY 17, 2020
    Cell & Molecular Biology
    Potential Treatment for Brain and Spinal Cord Injury is IDed
    Potential Treatment for Brain and Spinal Cord Injury is IDed
    Treatment options are limited for people that have suffered swelling-inducing injuries to their brain and spinal cord. N ...
    Written By: Carmen Leitch
    1 1
    MAY 16, 2020
    Neuroscience
    Stem Cell Method (Parkinson's) Could Avoid Transplant Rejection
    Stem Cell Method (Parkinson's) Could Avoid Transplant Rejection
    Researchers at McLean Hospital and Massachusetts General Hospital (MGH) have tested a stem cell treatment method that av ...
    Written By: Amanda Mikyska
    1
    MAY 16, 2020
    Cannabis Sciences
    Body's Own Cannabis Helps Us Forget Traumatic Events
    Body's Own Cannabis Helps Us Forget Traumatic Events
    Researchers have found that anandamide, often referred to as the body’s own cannabis, may help us forget traumatic ...
    Written By: Annie Lennon
    1 1
     
     
  • MAY 16, 2020
    Cancer
    Red Blood Cells: More than just an Oxygen Delivery Service
    Red Blood Cells: More than just an Oxygen Delivery Service
    The human body is a complex network of systems that often interact and affect each other. Recent work shows that red blo ...
    Written By: Jasper Cantrell
    2
    MAY 14, 2020
    Drug Discovery & Development
    Therapeutic for Gastrointestinal Tumors
    Therapeutic for Gastrointestinal Tumors
    The FDA has approved ripretinib (Qinlock) which is the first drug for fourth-line treatment of advanced gastrointestinal ...
    Written By: Nouran Amin
    1
    MAY 14, 2020
    Cancer
    New hope for immunotherapy for pediatric brain cancer
    New hope for immunotherapy for pediatric brain cancer
    Pediatric brain cancer is an especially tough pill to swallow. While one in four children does not survive medulloblasto ...
    Written By: Kathryn DeMuth Sullivan
    2
    MAY 14, 2020
    Immunology
    Antibody-laden Nanoparticles to Help COVID Patients Breathe Easy
    Antibody-laden Nanoparticles to Help COVID Patients Breathe Easy
    Antibodies are a powerful countermeasure against COVID-19. Not only can they relieve symptoms in patients experiencing s ...
    Written By: Tara Fernandes
    1
    MAY 13, 2020
    Drug Discovery & Development
    Approved Treatment for RET-mutant Cancers
    Approved Treatment for RET-mutant Cancers
    A drug was recently approved for treating three types of RET-mutant cancers: 1) non-small cell lung cancer (NSCLC) 2) ad ...
    Written By: Nouran Amin
    1
     
     
  • MAY 13, 2020
    Drug Discovery & Development
    Drug Targets Off Episodes of Parkinson
    Drug Targets Off Episodes of Parkinson
    A novel drug was approved by the FDA to target the “off” episodes of Parkinson disease. The drug is referred ...
    Written By: Nouran Amin
    1
    MAY 13, 2020
    Drug Discovery & Development
    Fecal Transplant Helps Fight off Antibiotic Resistance
    Fecal Transplant Helps Fight off Antibiotic Resistance
    Fecal transplants work by transporting fecal matter from healthy donors to those who are less healthy. Now, a study has ...
    Written By: Annie Lennon
    1
    MAY 13, 2020
    Drug Discovery & Development
    FDA Fast Tracks Vaccine for COVID-19
    FDA Fast Tracks Vaccine for COVID-19
    Biopharmaceutical company, Moderna, has announced that the US Food and Drug Administration has approved its experimental ...
    Written By: Annie Lennon
    2
    MAY 12, 2020
    Drug Discovery & Development
    Novel Drug Approved for Non-Small Cell Lung Cancer
    Novel Drug Approved for Non-Small Cell Lung Cancer
    The US Food and Drug Administration (FDA) recently approved a therapeutic for treating metastatic non-small cell lung ca ...
    Written By: Nouran Amin
    1
    MAY 12, 2020
    Cannabis Sciences
    Study Shows Cannabis May Block COVID-19 Infection
    Study Shows Cannabis May Block COVID-19 Infection
    Researchers from the University of Lethbridge, Canada, have found that cannabis may be able to block COVID-19 infections ...
    Written By: Annie Lennon
    3 4
     
     
  • MAY 12, 2020
    Drug Discovery & Development
    Does Herbal Drink from Madagascar Cure COVID-19?
    Does Herbal Drink from Madagascar Cure COVID-19?
    Andry Rajoelina, the president of Madagascar, an island off the coast of Southern Africa, has made claims that his count ...
    Written By: Annie Lennon
    1
    MAY 12, 2020
    Immunology
    Disabling Genes in Immune Cells Prevents Obesity
    Disabling Genes in Immune Cells Prevents Obesity
    Obesity is a $1.7 trillion problem in the United States — a value almost 10% of the nation’s gross domestic ...
    Written By: Tara Fernandes
    1
    MAY 11, 2020
    Cancer
    Using Deep Learning to Diagnose Breast Cancer Sub-Types
    Using Deep Learning to Diagnose Breast Cancer Sub-Types
    Cancer and computer programming may not sound like two things that go together. However, advanced programming techniques ...
    Written By: Jasper Cantrell
    1
    MAY 10, 2020
    Drug Discovery & Development
    Antiviral Drug Treats Naso-Pharyngeal Cancer
    Antiviral Drug Treats Naso-Pharyngeal Cancer
    Scientists at Hong Kong Baptist University (HKBU) developed a novel anti-Epstein-Barr virus (EBV) drug that can shrink t ...
    Written By: Nouran Amin
    1
    MAY 09, 2020
    Cancer
    Examining a Combination Therapy Against Gastric Cancer
    Examining a Combination Therapy Against Gastric Cancer
    Often when it comes to treatments for cancer, designing or discovering new leads can take years. One of the common pract ...
    Written By: Jasper Cantrell
    2
     
     
  • MAY 08, 2020
    Drug Discovery & Development
    Cholesterol Drugs May Boost Healthy Gut Bacteria in Obese People
    Cholesterol Drugs May Boost Healthy Gut Bacteria in Obese People
    While statins have long been known for their efficacy in treating high cholesterol, until recently, there was no evidenc ...
    Written By: Annie Lennon
    1
    MAY 07, 2020
    Immunology
    New COVID-19 Vaccine Defends Monkeys Against Infection
    New COVID-19 Vaccine Defends Monkeys Against Infection
    Researchers from Beijing-based Sinovac Biotech have reported preliminary results of a study into the development of a va ...
    Written By: Tara Fernandes
    2
    MAY 06, 2020
    Cancer
    Olanzapine useful for cancer patients managing nausea unrelated to chemo
    Olanzapine useful for cancer patients managing nausea unrelated to chemo
    A study published last week in JAMA Oncology reports that a generic drug called Olanzapine could be useful for cancer pa ...
    Written By: Kathryn DeMuth Sullivan
    2
    MAY 06, 2020
    Drug Discovery & Development
    Why Doctors are Repurposing Drugs to Treat COVID-19
    Why Doctors are Repurposing Drugs to Treat COVID-19
    Creating a drug from scratch is a lengthy process. Often taking years, given the rate of infection and deadliness of COV ...
    Written By: Annie Lennon
    1
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