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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Webinars

    • MAY 23, 2024 | 10:00 AM
      C.E. CREDITS
      Know thy sample: Five methods to quantify your protein and when to use them
      Know thy sample: Five methods to quantify your protein and when...
      Precise protein quantification is a crucial step in workflows involving protein extraction, isolation, and analysis. Accurate knowledge of the concentration of your protein sample is essenti...
      Speaker: Suzanne Smith, B.S. M.S.
      Sponsored By: Thermo Fisher Scientific
      28
      APR 03, 2024 | 12:00 PM
      Increasing iPSC Numbers through Systematic Culture Process Optimization in Bioreactors with Live Q&A
      Increasing iPSC Numbers through Systematic Culture Process Optimization...
      Human induced pluripotent stem cells (hiPSCs) are a powerful tool for innovative approaches, such as drug discovery, in vitro disease modelling, or regenerative therapies. However, such proc...
      Speaker: Dr. Benjamin Wolters, PhD
      Presented at: Bioprocessing Virtual Event Series 2024
      Sponsored By: Eppendorf
      2
      MAR 26, 2024 | 7:00 PM
      C.E. CREDITS
      Educational Webinar: Implementation of a Preemptive Pharmacogenomics Program at a Pediatric Health System
      Educational Webinar: Implementation of a Preemptive Pharmacogenomics...
      The implementation of a preemptive pharmacogenomics (PGx) program in a hospital setting requires a multidisciplinary approach to ensure seamless integration of each stage of the process for...
      Speaker: Steven Melnick. Ph.D., M.D. , Dr. David Mancuso, Pharm.D. CPh , MSPM
      Sponsored By: Thermo Fisher Scientific
      16
      MAR 26, 2024 | 11:00 AM
      Complete and Comprehensive Biomarker Discovery: TerraFlow for Flow Cytometry Analysis
      Complete and Comprehensive Biomarker Discovery: TerraFlow for...
      Ever wonder what you’re missing in your data? The sheer complexity of today’s flow and mass cytometry datasets demands automated solutions. Machine learning plugins only provide...
      Speaker: Dan Freeman , Pratip K. Chattopadhyay
      Sponsored By: terraFlow Bio
      19
      MAR 26, 2024 | 8:00 AM
      C.E. CREDITS
      Educational Webinar: Implementation of a Preemptive Pharmacogenomics Program at a Pediatric Health System
      Educational Webinar: Implementation of a Preemptive Pharmacogenomics...
      The implementation of a preemptive pharmacogenomics (PGx) program in a hospital setting requires a multidisciplinary approach to ensure seamless integration of each stage of the process for...
      Speaker: Steven Melnick. Ph.D., M.D. , Dr. David Mancuso, Pharm.D. CPh , MSPM
      Sponsored By: Thermo Fisher Scientific
      23
      On Demand
      C.E. CREDITS
      Utilizing Digital Microfluidics to Miniaturize and Automate Arrayed CRISPR Screening Workflows
      Utilizing Digital Microfluidics to Miniaturize and Automate Arrayed...
      Learning Objevtives: 1. Demonstrate Knowledge with gene editing, microfluidics and non-viral delivery methods. 2. Review the uses of a low-volume high-throughput transfection platform for ge...
      Speaker: Hugo Sinha, MASc
      Presented at: Laboratory Automation Virtual Event Series 2024
      2
      On Demand
      C.E. CREDITS
      Use of Human Stem Cell Models of Neurological Disease to Advance Drug Discovery
      Use of Human Stem Cell Models of Neurological Disease to Advance...
      Drug discovery programs require a robust panel of models and assays to identify and validate drug targets, support compound optimisation, and run mechanistic studies. Fully human in vitro mo...
      Speaker: Clare Jones, PhD
      Presented at: Neuroscience Virtual Event Series 2024
      2
      On Demand
      C.E. CREDITS
      Mouse Models of Alzheimer's Disease: New Behavioral Approaches
      Mouse Models of Alzheimer's Disease: New Behavioral Approaches
      Recent advances in gene editing has allowed the generation of advanced rodent research models, mimicking some aspects of human conditions. For neurodegenerative disorders such as Alzheimer&r...
      Speaker: Professor Bettina Platt, PhD
      Presented at: Neuroscience Virtual Event Series 2024
      4
      FEB 21, 2024 | 12:00 PM
      Challenging the 'Art' of SPR with Live Q&A
      Challenging the 'Art' of SPR with Live Q&A
      Surface plasmon resonance is a real-time and label-free technique that offers low sample consumption and high throughput when compared to other biophysical techniques and has been widely ado...
      Speaker: Stuart Knowling, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2024
      Sponsored By: Sartorius
      2
      FEB 21, 2024 | 6:00 AM
      Enhancing Synthesis Workflows Through Computer-Assisted Retrosynthesis with Live Q&A
      Enhancing Synthesis Workflows Through Computer-Assisted Retrosynthesis...
      Advancements in the field of drug discovery and chemical development have necessitated the integration of computer-assisted technologies to expedite processes, uncover efficiencies, and fost...
      Speaker: Dr. Ewa Gajewska, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2024
      Sponsored By: Merck
      2
      FEB 21, 2024 | 6:00 AM
      Leveraging Expert-Curated Knowledge from COSMIC and QIAGEN to Avoid Pitfalls, Qualify Candidate Drug Targets, and Accelerate Early Discovery
      Leveraging Expert-Curated Knowledge from COSMIC and QIAGEN to...
      The cancer drug discovery landscape is shifting. While research continues to grow in cost and complexity, the pace of development has never been faster. Biopharmaceutical companies can&rsquo...
      Speaker: Kyle Nilson, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2024
      Sponsored By: QIAGEN
      2
      On Demand
      C.E. CREDITS
      Proliferation Biomarkers in Drug Discovery and Development, The Immunoassay of Thymidine Kinase 1
      Proliferation Biomarkers in Drug Discovery and Development, The...
      Proliferation biomarkers are proteins that are up-regulated in growing cells. Immunological staining of tumor tissue can provide an indication of the aggressivity of the tumor and provide in...
      Speaker: Martin Shaw
      Presented at: Drug Discovery & Development Virtual Event Series 2024
      3
      On Demand
      C.E. CREDITS
      Development of an Interconnected Gut-Liver Model of Primary Human Origin Using Microphysiological Systems (MPS) for ADME Studies
      Development of an Interconnected Gut-Liver Model of Primary Human...
      Learning Objectives: 1. Summarize the benefits and challenges of current preclinical methods in drug discovery and development. 2. Review new alternative methodologies (NAMs) and microphysio...
      Speaker: Hailey Sze
      Presented at: Drug Discovery & Development Virtual Event Series 2024
      2
      FEB 08, 2024 | 10:00 AM
      Practical Considerations for Designing and Executing High-content Screens
      Practical Considerations for Designing and Executing High-content...
      High-content screening (HCS) is an imaging-based, multi-parametric strategy used in drug development that generates rich datasets through multiplexing strategically chosen fluorescent dyes a...
      Speaker: James Evans
      Sponsored By: Thermo Fisher Scientific
      21
      JAN 23, 2024 | 12:00 PM
      Retaining Cell Viability and Morphology in IPSCs: Vital Tools for Research
      Retaining Cell Viability and Morphology in IPSCs: Vital Tools...
      From drug discovery to organoid modeling of disease, stem cells are increasingly being used in research as a vital tool for scientific investigation. Due to the specialized nature of stem ce...
      Speaker: Daryl Cole
      Presented at: The Future of Biomedicine: Reproducible Advanced Cell Systems and Translational Insights
      3
      DEC 05, 2023 | 3:00 PM
      Revolutionizing Drug Development: Synthetic Nanodiscs
      Revolutionizing Drug Development: Synthetic Nanodiscs
      Most FDA-approved therapeutic drugs target transmembrane proteins, yet the development of monoclonal antibodies for multi-transmembrane protein targets has been limited. Despite the abundanc...
      Speaker: Dr. Donghui Ma
      Sponsored By: DIMA Biotech
      11
      OCT 24, 2023 | 9:00 PM
      Protein Expression Webinar
      Protein Expression Webinar
      This webinar is hosted by Thermo Fisher Scientific in collaboration with the Walter and Eliza Hall Institute of Medical Research (WEHI). The webinar aims to demonstrate the benefits of the E...
      Speaker: Marija Dramicanin, PhD , Roland Leathers, PhD
      Sponsored By: Thermo Fisher Scientific
      15
      OCT 24, 2023 | 10:00 AM
      An epic advance in epigenomics: Automated CUT&RUN enables chromatin profiling for scaled research & drug discovery applications
      An epic advance in epigenomics: Automated CUT&RUN enables chromatin...
      Dynamic changes in chromatin drive gene expression programs during cellular development and contribute to pathological changes underlying disease. To date, efforts to characterize chromatin...
      Speaker: Andrea Johnstone, Ph.D. , Lori Euler
      Sponsored By: Beckman Coulter Life Sciences
      30
      OCT 24, 2023 | 9:00 AM
      Introducing a streamlined solution to capture superior multiomic information at single-base resolution from limited DNA
      Introducing a streamlined solution to capture superior multiomic...
      DNA comprises molecular information stored in genetic and epigenetic bases, both of which are vital to our understanding of biology in health and disease. The interaction of genetics with th...
      Speaker: Páidí Creed, Ph.D. , Nick Harding, Ph.D.
      Sponsored By: biomodal
      9
      OCT 24, 2023 | 8:00 AM
      Scaling Up Organoid Research: A New Approach with Assay-Ready Organoids
      Scaling Up Organoid Research: A New Approach with Assay-Ready...
      Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
      Speaker: Angeline Lim , Andy Bashford
      Sponsored By: Molecular Devices
      9
      OCT 24, 2023 | 10:00 AM
      Scaling Up Organoid Research: A New Approach with Assay-Ready Organoids
      Scaling Up Organoid Research: A New Approach with Assay-Ready...
      Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
      Speaker: Angeline Lim , Andy Bashford
      Sponsored By: Molecular Devices
      12
      OCT 05, 2023 | 1:00 AM
      Upscaling Organoids: Automated solutions for high throughput cell applications
      Upscaling Organoids: Automated solutions for high throughput cell...
      Organoids continue to gain traction in drug discovery efforts as they offer a more biologically relevant disease model than traditional approaches. But they aren't without challenges. Jo...
      Speaker: Nathan Gödde , Mathilde Cordellier
      Sponsored By: Revvity
      21
      OCT 04, 2023 | 10:30 AM
      Empowering Oncology Research: Transmembrane Proteins and Cutting-edge Production Platforms with Live Q&A
      Empowering Oncology Research: Transmembrane Proteins and Cutting-edge...
      Transmembrane proteins play a critical role in signal transduction, cell adhesion, nutrient uptake, and immune response modulation....
      Speaker: Fang-Yi Chu, PhD
      Presented at: Cancer Research & Immuno-Oncology Week Virtual Event Series 2023
      Sponsored By: Sino Biological
      1
      SEP 28, 2023 | 7:00 AM
      Optimizing CAR structures to enhance efficacy in solid tumours; moving from linear to lateral architectures.
      Optimizing CAR structures to enhance efficacy in solid tumours;...
      Webinars will be available for unlimited on-demand viewing after live event. Labroots is approved as a provider of continuing education programs in the clinical laboratory sciences by the AS...
      Speaker: Marc Davies, PhD , Stacie Chvatal, PhD
      Sponsored By: Axion BioSystems
      12
    MAY 23, 2024 | 10:00 AM
    C.E. CREDITS
    Know thy sample: Five methods to quantify your protein and when to use them
    Know thy sample: Five methods to quantify your protein and when...
    Precise protein quantification is a crucial step in workflows involving protein extraction, isolation, and analysis. Accurate knowledge of the concentration of your protein sample is essenti...
    Speaker: Suzanne Smith, B.S. M.S.
    Sponsored By: Thermo Fisher Scientific
    28
    APR 03, 2024 | 12:00 PM
    Increasing iPSC Numbers through Systematic Culture Process Optimization in Bioreactors with Live Q&A
    Increasing iPSC Numbers through Systematic Culture Process Optimization...
    Human induced pluripotent stem cells (hiPSCs) are a powerful tool for innovative approaches, such as drug discovery, in vitro disease modelling, or regenerative therapies. However, such proc...
    Speaker: Dr. Benjamin Wolters, PhD
    Presented at: Bioprocessing Virtual Event Series 2024
    Sponsored By: Eppendorf
    2
    MAR 26, 2024 | 7:00 PM
    C.E. CREDITS
    Educational Webinar: Implementation of a Preemptive Pharmacogenomics Program at a Pediatric Health System
    Educational Webinar: Implementation of a Preemptive Pharmacogenomics...
    The implementation of a preemptive pharmacogenomics (PGx) program in a hospital setting requires a multidisciplinary approach to ensure seamless integration of each stage of the process for...
    Speaker: Steven Melnick. Ph.D., M.D. , Dr. David Mancuso, Pharm.D. CPh , MSPM
    Sponsored By: Thermo Fisher Scientific
    16
    MAR 26, 2024 | 11:00 AM
    Complete and Comprehensive Biomarker Discovery: TerraFlow for Flow Cytometry Analysis
    Complete and Comprehensive Biomarker Discovery: TerraFlow for...
    Ever wonder what you’re missing in your data? The sheer complexity of today’s flow and mass cytometry datasets demands automated solutions. Machine learning plugins only provide...
    Speaker: Dan Freeman , Pratip K. Chattopadhyay
    Sponsored By: terraFlow Bio
    19
    MAR 26, 2024 | 8:00 AM
    C.E. CREDITS
    Educational Webinar: Implementation of a Preemptive Pharmacogenomics Program at a Pediatric Health System
    Educational Webinar: Implementation of a Preemptive Pharmacogenomics...
    The implementation of a preemptive pharmacogenomics (PGx) program in a hospital setting requires a multidisciplinary approach to ensure seamless integration of each stage of the process for...
    Speaker: Steven Melnick. Ph.D., M.D. , Dr. David Mancuso, Pharm.D. CPh , MSPM
    Sponsored By: Thermo Fisher Scientific
    23
     
     
  • On Demand
    C.E. CREDITS
    Utilizing Digital Microfluidics to Miniaturize and Automate Arrayed CRISPR Screening Workflows
    Utilizing Digital Microfluidics to Miniaturize and Automate Arrayed...
    Learning Objevtives: 1. Demonstrate Knowledge with gene editing, microfluidics and non-viral delivery methods. 2. Review the uses of a low-volume high-throughput transfection platform for ge...
    Speaker: Hugo Sinha, MASc
    Presented at: Laboratory Automation Virtual Event Series 2024
    2
    On Demand
    C.E. CREDITS
    Use of Human Stem Cell Models of Neurological Disease to Advance Drug Discovery
    Use of Human Stem Cell Models of Neurological Disease to Advance...
    Drug discovery programs require a robust panel of models and assays to identify and validate drug targets, support compound optimisation, and run mechanistic studies. Fully human in vitro mo...
    Speaker: Clare Jones, PhD
    Presented at: Neuroscience Virtual Event Series 2024
    2
    On Demand
    C.E. CREDITS
    Mouse Models of Alzheimer's Disease: New Behavioral Approaches
    Mouse Models of Alzheimer's Disease: New Behavioral Approaches
    Recent advances in gene editing has allowed the generation of advanced rodent research models, mimicking some aspects of human conditions. For neurodegenerative disorders such as Alzheimer&r...
    Speaker: Professor Bettina Platt, PhD
    Presented at: Neuroscience Virtual Event Series 2024
    4
    FEB 21, 2024 | 12:00 PM
    Challenging the 'Art' of SPR with Live Q&A
    Challenging the 'Art' of SPR with Live Q&A
    Surface plasmon resonance is a real-time and label-free technique that offers low sample consumption and high throughput when compared to other biophysical techniques and has been widely ado...
    Speaker: Stuart Knowling, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2024
    Sponsored By: Sartorius
    2
    FEB 21, 2024 | 6:00 AM
    Enhancing Synthesis Workflows Through Computer-Assisted Retrosynthesis with Live Q&A
    Enhancing Synthesis Workflows Through Computer-Assisted Retrosynthesis...
    Advancements in the field of drug discovery and chemical development have necessitated the integration of computer-assisted technologies to expedite processes, uncover efficiencies, and fost...
    Speaker: Dr. Ewa Gajewska, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2024
    Sponsored By: Merck
    2
     
     
  • FEB 21, 2024 | 6:00 AM
    Leveraging Expert-Curated Knowledge from COSMIC and QIAGEN to Avoid Pitfalls, Qualify Candidate Drug Targets, and Accelerate Early Discovery
    Leveraging Expert-Curated Knowledge from COSMIC and QIAGEN to...
    The cancer drug discovery landscape is shifting. While research continues to grow in cost and complexity, the pace of development has never been faster. Biopharmaceutical companies can&rsquo...
    Speaker: Kyle Nilson, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2024
    Sponsored By: QIAGEN
    2
    On Demand
    C.E. CREDITS
    Proliferation Biomarkers in Drug Discovery and Development, The Immunoassay of Thymidine Kinase 1
    Proliferation Biomarkers in Drug Discovery and Development, The...
    Proliferation biomarkers are proteins that are up-regulated in growing cells. Immunological staining of tumor tissue can provide an indication of the aggressivity of the tumor and provide in...
    Speaker: Martin Shaw
    Presented at: Drug Discovery & Development Virtual Event Series 2024
    3
    On Demand
    C.E. CREDITS
    Development of an Interconnected Gut-Liver Model of Primary Human Origin Using Microphysiological Systems (MPS) for ADME Studies
    Development of an Interconnected Gut-Liver Model of Primary Human...
    Learning Objectives: 1. Summarize the benefits and challenges of current preclinical methods in drug discovery and development. 2. Review new alternative methodologies (NAMs) and microphysio...
    Speaker: Hailey Sze
    Presented at: Drug Discovery & Development Virtual Event Series 2024
    2
    FEB 08, 2024 | 10:00 AM
    Practical Considerations for Designing and Executing High-content Screens
    Practical Considerations for Designing and Executing High-content...
    High-content screening (HCS) is an imaging-based, multi-parametric strategy used in drug development that generates rich datasets through multiplexing strategically chosen fluorescent dyes a...
    Speaker: James Evans
    Sponsored By: Thermo Fisher Scientific
    21
    JAN 23, 2024 | 12:00 PM
    Retaining Cell Viability and Morphology in IPSCs: Vital Tools for Research
    Retaining Cell Viability and Morphology in IPSCs: Vital Tools...
    From drug discovery to organoid modeling of disease, stem cells are increasingly being used in research as a vital tool for scientific investigation. Due to the specialized nature of stem ce...
    Speaker: Daryl Cole
    Presented at: The Future of Biomedicine: Reproducible Advanced Cell Systems and Translational Insights
    3
     
     
  • DEC 05, 2023 | 3:00 PM
    Revolutionizing Drug Development: Synthetic Nanodiscs
    Revolutionizing Drug Development: Synthetic Nanodiscs
    Most FDA-approved therapeutic drugs target transmembrane proteins, yet the development of monoclonal antibodies for multi-transmembrane protein targets has been limited. Despite the abundanc...
    Speaker: Dr. Donghui Ma
    Sponsored By: DIMA Biotech
    11
    OCT 24, 2023 | 9:00 PM
    Protein Expression Webinar
    Protein Expression Webinar
    This webinar is hosted by Thermo Fisher Scientific in collaboration with the Walter and Eliza Hall Institute of Medical Research (WEHI). The webinar aims to demonstrate the benefits of the E...
    Speaker: Marija Dramicanin, PhD , Roland Leathers, PhD
    Sponsored By: Thermo Fisher Scientific
    15
    OCT 24, 2023 | 10:00 AM
    An epic advance in epigenomics: Automated CUT&RUN enables chromatin profiling for scaled research & drug discovery applications
    An epic advance in epigenomics: Automated CUT&RUN enables chromatin...
    Dynamic changes in chromatin drive gene expression programs during cellular development and contribute to pathological changes underlying disease. To date, efforts to characterize chromatin...
    Speaker: Andrea Johnstone, Ph.D. , Lori Euler
    Sponsored By: Beckman Coulter Life Sciences
    30
    OCT 24, 2023 | 9:00 AM
    Introducing a streamlined solution to capture superior multiomic information at single-base resolution from limited DNA
    Introducing a streamlined solution to capture superior multiomic...
    DNA comprises molecular information stored in genetic and epigenetic bases, both of which are vital to our understanding of biology in health and disease. The interaction of genetics with th...
    Speaker: Páidí Creed, Ph.D. , Nick Harding, Ph.D.
    Sponsored By: biomodal
    9
    OCT 24, 2023 | 8:00 AM
    Scaling Up Organoid Research: A New Approach with Assay-Ready Organoids
    Scaling Up Organoid Research: A New Approach with Assay-Ready...
    Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
    Speaker: Angeline Lim , Andy Bashford
    Sponsored By: Molecular Devices
    9
     
     
  • OCT 24, 2023 | 10:00 AM
    Scaling Up Organoid Research: A New Approach with Assay-Ready Organoids
    Scaling Up Organoid Research: A New Approach with Assay-Ready...
    Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
    Speaker: Angeline Lim , Andy Bashford
    Sponsored By: Molecular Devices
    12
    OCT 05, 2023 | 1:00 AM
    Upscaling Organoids: Automated solutions for high throughput cell applications
    Upscaling Organoids: Automated solutions for high throughput cell...
    Organoids continue to gain traction in drug discovery efforts as they offer a more biologically relevant disease model than traditional approaches. But they aren't without challenges. Jo...
    Speaker: Nathan Gödde , Mathilde Cordellier
    Sponsored By: Revvity
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