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    Drug screening with cancer cells

    Developing safe and effective drugs to treat cancer involves intensive studies using various model systems including in vitro analysis with cancer cells. Cancer cell lines are generated from the tissue of cancer patients. Developmental drugs are then used to treat the cells in a laboratory setting where the effects on cell growth and death can be monitored.

    Webinars

    • MAR 31, 2020 | 7:00 AM
      Investigation of NK cell-driven tumor immunity using novel image cytometry detection method
      Investigation of NK cell-driven tumor immunity using novel image...
      DATE: March 31, 2020 TIME: 7:00am PT, 10:00am PT Please join us for this webinar, during which we will present and discuss the promotion of NK cell-driven tumor immunity. In addition, we wil...
      Speaker: Lucas Ferrari de Andrade, Ph.D. , Leo Chan, Ph.D.
      Sponsored By: Nexcelom Bioscience
      10
      MAR 27, 2020 | 9:00 AM
      Modified Dental Composite for Bone Repair
      Modified Dental Composite for Bone Repair
      DATE: March 27, 2020 TIME: 9:00am PDT, 12:00pm EDT Osteoporosis causes a decrease in bone density, along with deterioration of the bone’s microarchitecture at a faster rate than normal...
      Speaker: Mayda Arshad
      Sponsored By: Thermo Fisher Scientific/Gibco
      11
      MAR 26, 2020 | 9:00 AM
      Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell Engineering and Beyond
      Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell...
      DATE: March 26, 2020 TIME: 9:00am PST, 12:00pm EST Growing demand for precision therapy and the recent successes with CAR-T cells for cancer treatment...
      Speaker: Namritha Ravinder
      Sponsored By: Thermo Fisher Scientific
      7
      MAR 24, 2020 | 10:00 AM
      Save your time on data analysis with new Batch Analysis feature in Axon pCLAMP 11 Software
      Save your time on data analysis with new Batch Analysis feature...
      DATE: March 24, 2020 TIME: 10:00 am PDT, 1:00pm EDT The Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Rece...
      Speaker: Jeffrey Tang, Ph.D.
      Sponsored By: Molecular Devices
      10
      FEB 26, 2020 | 9:00 AM
      CRISPR Based Screening: Advantages of Transcriptional Activators and Inhibitors
      CRISPR Based Screening: Advantages of Transcriptional Activators...
      CRISPR revolutionized gene editing, but multi-target screening remains a complex goal. In addition, the fast pace of CRISPR technology development has brought sophisticated options for libra...
      Speaker: Andrew Ravanelli, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2 1
      FEB 25, 2020 | 9:00 AM
      CAR-T Generation for Identity, Purity and Potency Assay Testing
      CAR-T Generation for Identity, Purity and Potency Assay Testing
      Learn about how to generate a small scale CAR-T workflow using ThermoFisher products See detailed characterization tools that can be utilized and applied in a CAR-T workflow...
      Speaker: Tia Hexom, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 1
      FEB 05, 2020 | 8:00 AM
      C.E. CREDITS
      Emerging Issues in the Coagulation Laboratory
      Emerging Issues in the Coagulation Laboratory
      Learn how new hemophilia and anticoagulant therapies impact coagulation assays and clinical decisions in our educational session....
      Speaker: Donna Castellone, MS, MASCP, MT(ASCP) SH
      Presented at: Stago EdVantage Virtual University
      Sponsored By: Diagnostica Stago, Inc.
      10 1
      JAN 30, 2020 | 9:00 AM
      An Automated Cancer Organoid Culture Platform to Accelerate Research and Drug Screening
      An Automated Cancer Organoid Culture Platform to Accelerate Research...
      DATE: January 30, 2020 TIME: 9:00am PST, 12:00pm EST Recent advances in in vitro 3D cellular culture technologies, such as organoids, rapidly developed and established novel, more physiologi...
      Speaker: Brooke Schuster
      Sponsored By: Thermo Fisher Scientific/Gibco
      10
      JAN 23, 2020 | 9:00 AM
      A Workflow for Knock-in Genome Editing: Simplified
      A Workflow for Knock-in Genome Editing: Simplified
      DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
      Speaker: Matthew Poling, PhD
      Sponsored By: Thermo Fisher Scientific
      17
      JAN 14, 2020 | 8:00 AM
      CiPA initiative and validation of high-throughput methods to characterize compound effects in human iPSC-derived cardiomyocytes
      CiPA initiative and validation of high-throughput methods to characterize...
      DATE: January 14, 2019 TIME: 8:00am PST Drug-induced QT interval prolongation and Torsades de Pointes (TdP) arrhythmias are the leading causes for drug withdrawals from market and compound a...
      Speaker: Muthukrishnan Renganathan, PhD , Panida Lertkiatmongkol, PhD , Oksana Sirenko, PhD , Carole Crittenden
      Sponsored By: Molecular Devices, Eurofins Discovery
      3
      JAN 01, 2020 | 6:00 AM
      Human Tissue models for better therapies
      Human Tissue models for better therapies
      The OrganoPlate is a microtiterplate based Organ-on-a-Chip platform for high throughput drug safety and efficacy screening. It contains up to 96 cell culture chambers that allow co-culture o...
      Speaker: Sebastiaan Trietsch, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
      Uncovering the mechanism of stress-resistant DNA replication in...
      Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
      Speaker: Chames Kermi, PhD, PharmD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Organoids: A Revolutionary New Tool for Drug Screening
      Organoids: A Revolutionary New Tool for Drug Screening
      “The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
      Speaker: Rekha Pal, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Microfabricated Human Liver Tissues for Drug Development
      Microfabricated Human Liver Tissues for Drug Development
      The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...
      Speaker: Salman Khetani, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      DEC 05, 2019 | 9:00 AM
      Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments
      Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments
      DATE: December 5, 2019TIME: 9:00am PST, 12:00pm EST Characterization of the spatial distribution and abundance of proteins and mRNAs with morphological context within tissues e...
      Speaker: Mathias Holpert, PhD , Traci DeGeer, BS, HT (ASCP) HTL, QIHC
      Sponsored By: Leica Biosystems, NanoString Technologies
      8
      OCT 29, 2019 | 7:00 AM
      Optimizing high-content screening tools for physiologically-relevant 3D in vitro models
      Optimizing high-content screening tools for physiologically-relevant...
      DATE: October 29, 2019TIME: 7:00am PDT3D cell culture systems have recently emerged as tools for reproducing the cellular environment and the organization of tissues/organs, where cel...
      Speaker: Elodie Vandenhaute , Zied Souguir , Daniel O'Connor
      Sponsored By: Molecular Devices
      8
      OCT 09, 2019 | 7:30 AM
      Keynote Presentation: Pairing protein profiling with drug screens uncovers an effective therapy against high risk leukemia
      Keynote Presentation: Pairing protein profiling with drug screens...
      Acute lymphoblastic leukemia is the most common cancer in children and adolescents. While current treatments have resulted in 85-90% cure, the remaining 10-15% cases represent the leading cau...
      Speaker: Ernesto Diaz-Flores, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      2
      SEP 27, 2019 | 9:00 AM
      Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
      Investigating how Tpz-1 may be used as a novel therapeutic agent...
      DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
      Speaker: Jessica Hess
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
      SEP 24, 2019 | 8:00 AM
      Interrogating 3D spheroid versus 2D monolayer cell models in drug discovery using cell health microplate assays
      Interrogating 3D spheroid versus 2D monolayer cell models in drug...
      DATE: September 24, 2019TIME: 7:00am PDTHigh throughput screening (HTS) is an effective method for identifying putative active compounds for therapeutics. Assays that evaluate changes i...
      Speaker: Dr. Adyary Fallarero, Ph.D. Adjunct Professor/Docent in Pharmaceutical Biology , Dr. Leticia Montoya, Ph.D., Chemistry and Biochemistry
      Sponsored By: Thermo Fisher Scientific
      9
      SEP 17, 2019 | 6:00 AM
      Post-translational modification enrichment and quantitation for precision medicine and drug development
      Post-translational modification enrichment and quantitation for...
      DATE: September 17, 2019TIME: 6:00 am PDT, 9:00am EDT, 2:00pm BST, 3:00pm CEST Abstract: Learning Objectives: one two Webina...
      Speaker: Connie Jimenez, PhD , Manuel Tzouros, PhD
      Sponsored By: Cell Signaling Technology
      8 2
      AUG 22, 2019 | 6:00 AM
      In Vitro Screening Approaches to Estimate Human Hepatic Responses to Xenobiotic Exposures
      In Vitro Screening Approaches to Estimate Human Hepatic Responses...
      Prediction of human response to chemical exposures is the primary challenge of pharmaceutical and environmental toxicology research. The complexity of human responses to xenobiotic exposures...
      Speaker: Stephen Ferguson, PhD
      Presented at: Forensics & Toxicology 2019
      1
      AUG 14, 2019 | 9:00 AM
      Continuous Improvement in Sample Management
      Continuous Improvement in Sample Management
      DATE: August 14, 2019TIME: 9:00am PT. 12:00pm ET Implementation of Lean Methodology in Biobanking Operations to standardize sample management processes is effective. Each proce...
      Speaker: Bill Lovatt , Jay Patel , Zachary Kogler
      Sponsored By: Brooks Life Sciences
      3
      JUL 30, 2019 | 6:00 AM
      Overview of the new ERA Guidelines: Changes and Revisions
      Overview of the new ERA Guidelines: Changes and Revisions
      DATE: July 30, 2019TIME: 6:00am PT, 9:00am ET The current version of the EMA Guideline for the environmental risk assessment of human drugs was published in 2006. This guidance...
      Speaker: Erick Nfon, PhD
      Sponsored By: Smithers
      4
      JUN 20, 2019 | 6:00 AM
      See Further: Expanded Carrier Screening Tools That Take You From Sample to Insight
      See Further: Expanded Carrier Screening Tools That Take You From...
      Inherited disorders affect millions of people globally. These diseases significantly impact lives of patients and their families, and in addition, also results in substantial socio-economic i...
      Speaker: Raed Samara, PhD , Rupert Yip, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
    MAR 31, 2020 | 7:00 AM
    Investigation of NK cell-driven tumor immunity using novel image cytometry detection method
    Investigation of NK cell-driven tumor immunity using novel image...
    DATE: March 31, 2020 TIME: 7:00am PT, 10:00am PT Please join us for this webinar, during which we will present and discuss the promotion of NK cell-driven tumor immunity. In addition, we wil...
    Speaker: Lucas Ferrari de Andrade, Ph.D. , Leo Chan, Ph.D.
    Sponsored By: Nexcelom Bioscience
    10
    MAR 27, 2020 | 9:00 AM
    Modified Dental Composite for Bone Repair
    Modified Dental Composite for Bone Repair
    DATE: March 27, 2020 TIME: 9:00am PDT, 12:00pm EDT Osteoporosis causes a decrease in bone density, along with deterioration of the bone’s microarchitecture at a faster rate than normal...
    Speaker: Mayda Arshad
    Sponsored By: Thermo Fisher Scientific/Gibco
    11
    MAR 26, 2020 | 9:00 AM
    Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell Engineering and Beyond
    Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell...
    DATE: March 26, 2020 TIME: 9:00am PST, 12:00pm EST Growing demand for precision therapy and the recent successes with CAR-T cells for cancer treatment...
    Speaker: Namritha Ravinder
    Sponsored By: Thermo Fisher Scientific
    7
    MAR 24, 2020 | 10:00 AM
    Save your time on data analysis with new Batch Analysis feature in Axon pCLAMP 11 Software
    Save your time on data analysis with new Batch Analysis feature...
    DATE: March 24, 2020 TIME: 10:00 am PDT, 1:00pm EDT The Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Rece...
    Speaker: Jeffrey Tang, Ph.D.
    Sponsored By: Molecular Devices
    10
    FEB 26, 2020 | 9:00 AM
    CRISPR Based Screening: Advantages of Transcriptional Activators and Inhibitors
    CRISPR Based Screening: Advantages of Transcriptional Activators...
    CRISPR revolutionized gene editing, but multi-target screening remains a complex goal. In addition, the fast pace of CRISPR technology development has brought sophisticated options for libra...
    Speaker: Andrew Ravanelli, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2 1
     
     
  • FEB 25, 2020 | 9:00 AM
    CAR-T Generation for Identity, Purity and Potency Assay Testing
    CAR-T Generation for Identity, Purity and Potency Assay Testing
    Learn about how to generate a small scale CAR-T workflow using ThermoFisher products See detailed characterization tools that can be utilized and applied in a CAR-T workflow...
    Speaker: Tia Hexom, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 1
    FEB 05, 2020 | 8:00 AM
    C.E. CREDITS
    Emerging Issues in the Coagulation Laboratory
    Emerging Issues in the Coagulation Laboratory
    Learn how new hemophilia and anticoagulant therapies impact coagulation assays and clinical decisions in our educational session....
    Speaker: Donna Castellone, MS, MASCP, MT(ASCP) SH
    Presented at: Stago EdVantage Virtual University
    Sponsored By: Diagnostica Stago, Inc.
    10 1
    JAN 30, 2020 | 9:00 AM
    An Automated Cancer Organoid Culture Platform to Accelerate Research and Drug Screening
    An Automated Cancer Organoid Culture Platform to Accelerate Research...
    DATE: January 30, 2020 TIME: 9:00am PST, 12:00pm EST Recent advances in in vitro 3D cellular culture technologies, such as organoids, rapidly developed and established novel, more physiologi...
    Speaker: Brooke Schuster
    Sponsored By: Thermo Fisher Scientific/Gibco
    10
    JAN 23, 2020 | 9:00 AM
    A Workflow for Knock-in Genome Editing: Simplified
    A Workflow for Knock-in Genome Editing: Simplified
    DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
    Speaker: Matthew Poling, PhD
    Sponsored By: Thermo Fisher Scientific
    17
    JAN 14, 2020 | 8:00 AM
    CiPA initiative and validation of high-throughput methods to characterize compound effects in human iPSC-derived cardiomyocytes
    CiPA initiative and validation of high-throughput methods to characterize...
    DATE: January 14, 2019 TIME: 8:00am PST Drug-induced QT interval prolongation and Torsades de Pointes (TdP) arrhythmias are the leading causes for drug withdrawals from market and compound a...
    Speaker: Muthukrishnan Renganathan, PhD , Panida Lertkiatmongkol, PhD , Oksana Sirenko, PhD , Carole Crittenden
    Sponsored By: Molecular Devices, Eurofins Discovery
    3
     
     
  • JAN 01, 2020 | 6:00 AM
    Human Tissue models for better therapies
    Human Tissue models for better therapies
    The OrganoPlate is a microtiterplate based Organ-on-a-Chip platform for high throughput drug safety and efficacy screening. It contains up to 96 cell culture chambers that allow co-culture o...
    Speaker: Sebastiaan Trietsch, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
    Uncovering the mechanism of stress-resistant DNA replication in...
    Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
    Speaker: Chames Kermi, PhD, PharmD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Organoids: A Revolutionary New Tool for Drug Screening
    Organoids: A Revolutionary New Tool for Drug Screening
    “The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
    Speaker: Rekha Pal, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Microfabricated Human Liver Tissues for Drug Development
    Microfabricated Human Liver Tissues for Drug Development
    The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...
    Speaker: Salman Khetani, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    DEC 05, 2019 | 9:00 AM
    Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments
    Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments
    DATE: December 5, 2019TIME: 9:00am PST, 12:00pm EST Characterization of the spatial distribution and abundance of proteins and mRNAs with morphological context within tissues e...
    Speaker: Mathias Holpert, PhD , Traci DeGeer, BS, HT (ASCP) HTL, QIHC
    Sponsored By: Leica Biosystems, NanoString Technologies
    8
     
     
  • OCT 29, 2019 | 7:00 AM
    Optimizing high-content screening tools for physiologically-relevant 3D in vitro models
    Optimizing high-content screening tools for physiologically-relevant...
    DATE: October 29, 2019TIME: 7:00am PDT3D cell culture systems have recently emerged as tools for reproducing the cellular environment and the organization of tissues/organs, where cel...
    Speaker: Elodie Vandenhaute , Zied Souguir , Daniel O'Connor
    Sponsored By: Molecular Devices
    8
    OCT 09, 2019 | 7:30 AM
    Keynote Presentation: Pairing protein profiling with drug screens uncovers an effective therapy against high risk leukemia
    Keynote Presentation: Pairing protein profiling with drug screens...
    Acute lymphoblastic leukemia is the most common cancer in children and adolescents. While current treatments have resulted in 85-90% cure, the remaining 10-15% cases represent the leading cau...
    Speaker: Ernesto Diaz-Flores, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    2
    SEP 27, 2019 | 9:00 AM
    Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
    Investigating how Tpz-1 may be used as a novel therapeutic agent...
    DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
    Speaker: Jessica Hess
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
    SEP 24, 2019 | 8:00 AM
    Interrogating 3D spheroid versus 2D monolayer cell models in drug discovery using cell health microplate assays
    Interrogating 3D spheroid versus 2D monolayer cell models in drug...
    DATE: September 24, 2019TIME: 7:00am PDTHigh throughput screening (HTS) is an effective method for identifying putative active compounds for therapeutics. Assays that evaluate changes i...
    Speaker: Dr. Adyary Fallarero, Ph.D. Adjunct Professor/Docent in Pharmaceutical Biology , Dr. Leticia Montoya, Ph.D., Chemistry and Biochemistry
    Sponsored By: Thermo Fisher Scientific
    9
    SEP 17, 2019 | 6:00 AM
    Post-translational modification enrichment and quantitation for precision medicine and drug development
    Post-translational modification enrichment and quantitation for...
    DATE: September 17, 2019TIME: 6:00 am PDT, 9:00am EDT, 2:00pm BST, 3:00pm CEST Abstract: Learning Objectives: one two Webina...
    Speaker: Connie Jimenez, PhD , Manuel Tzouros, PhD
    Sponsored By: Cell Signaling Technology
    8 2
     
     
  • AUG 22, 2019 | 6:00 AM
    In Vitro Screening Approaches to Estimate Human Hepatic Responses to Xenobiotic Exposures
    In Vitro Screening Approaches to Estimate Human Hepatic Responses...
    Prediction of human response to chemical exposures is the primary challenge of pharmaceutical and environmental toxicology research. The complexity of human responses to xenobiotic exposures...
    Speaker: Stephen Ferguson, PhD
    Presented at: Forensics & Toxicology 2019
    1
    AUG 14, 2019 | 9:00 AM
    Continuous Improvement in Sample Management
    Continuous Improvement in Sample Management
    DATE: August 14, 2019TIME: 9:00am PT. 12:00pm ET Implementation of Lean Methodology in Biobanking Operations to standardize sample management processes is effective. Each proce...
    Speaker: Bill Lovatt , Jay Patel , Zachary Kogler
    Sponsored By: Brooks Life Sciences
    3
    JUL 30, 2019 | 6:00 AM
    Overview of the new ERA Guidelines: Changes and Revisions
    Overview of the new ERA Guidelines: Changes and Revisions
    DATE: July 30, 2019TIME: 6:00am PT, 9:00am ET The current version of the EMA Guideline for the environmental risk assessment of human drugs was published in 2006. This guidance...
    Speaker: Erick Nfon, PhD
    Sponsored By: Smithers
    4
    JUN 20, 2019 | 6:00 AM
    See Further: Expanded Carrier Screening Tools That Take You From Sample to Insight
    See Further: Expanded Carrier Screening Tools That Take You From...
    Inherited disorders affect millions of people globally. These diseases significantly impact lives of patients and their families, and in addition, also results in substantial socio-economic i...
    Speaker: Raed Samara, PhD , Rupert Yip, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
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