Gene Transfer: the insertion of copies of a gene into living cells in order to induce synthesis of the gene's product: the desired gene may be microinjected directly into the cell or it may be inserted into the core of a virus by gene splicing and the virus allowed to infect the cell for replication of the gene in the cell's DNA.
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Gene therapy is defined as the treatment of disease by transfer of genetic material into cells, to prevent, treat and potentially even cure a disease. Gene therapies can work by several mech...
A fundamental challenge for cystic fibrosis (CF) gene therapy is ensuring sufficient transduction of airway epithelial cells to achieve therapeutic correction. Vehicles such as lysophosphati...
CGX10 Cell Isolation System: Introduction, Utility, and Assessment in a GMP-grade Environment for Multiparametric Cell Sorting A future of long-term, minimally toxic immunotherapy personaliz...
AAVs and LNPs are complementary gene transfer systems with respect to immunogenicity, tissue tropism and types of nucleic acids, which can be delivered. AUC provides a wealth of orthogonal a...
Join us for an educational webinar that delves into the fascinating world of Extracellular Vesicles (EVs) and their impact on biomedical research and medicine. In collaboration with ExoVecto...
Adeno-associated virus (AAV) are increasingly produced as they hold tremendous potential in gene therapy. At research level, small quantities are produced for proof of concept studies. Howev...
The use of adeno-associated viruses (AAV) as gene delivery vectors has vast potential for the treatment of many severe human diseases. A small group of intensively studied AAV capsids have b...
Chimeric antigen receptor (CAR)-reprogrammed immune cells offer exciting therapeutic potential for addressing oncology, autoimmune diseases, transplant medicine, and infections. However, cur...
Date: March 30, 2023 Time: 5:00pm (PST), 8:00pm (EST) March 31, 2023 9:00am (JST) Chimeric antigen receptor T cell (CAR-T) therapy is still challenging in targeting solid malignancies. The q...
Date: October 6, 2022 Time: Time: 9:30am IST, 12:00pm SGT, 1:00pm JST, KThe discovery of the CRISPR/Cas9 system has transformed research and now allows straightforward alterations in the geno...
Objective : Evaluation of EDTA-gel blood collection tubes from remote locations for NIPS (Non-invasive prenatal testing). Design: Paired comparisons Population: 61 pregnant women from Britis...