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GPCR
GPCR: G-protein-coupled receptors (GPCRs) are the largest and most diverse group of membrane receptors in eukaryotes. These cell surface receptors act like an inbox for messages in the form of light energy, peptides, lipids, sugars, and proteins. Such messages inform cells about the presence or absence of life-sustaining light or nutrients in their environment, or they convey information sent by other cells.
FEB 22, 2023 | 10:30 AM
Immunogens with native conformation and a high-throughput IgG cloning platform are two of the most important key components for high quality lead antibody molecules discovery. DIMABIO’...
FEB 22, 2023 | 5:30 AM
G Protein Coupled Receptors (GPCRs) are therapeutic targets for many medications used to treat a variety of disease states. A large number of genetic variants have been identified in the gen...
FEB 15, 2023 | 7:00 AM
Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
AUG 17, 2022 | 10:00 PM
Date: August 18, 2022 Time: 3pm AEST | 1pm SGT | 2pm JP/KR Kirsten rat sarcoma viral oncogene homologue (KRAS) is the most frequently mutated oncogene, present in approximately 25% of tumors...
JUL 19, 2022 | 8:00 AM
Date: July 19, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Cryo-EM is rapidly becoming the method of choice for structural biologists and biochemists around the world, helping thes...
JUN 22, 2022 | 10:00 AM
Date: June 22, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Rabbits have a robust and unique immune system that enables the generated antibodies with superior specificity, affinity,...
APR 26, 2022 | 8:00 AM
Date: April 26, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) C-C motif chemokine receptor-like 2 (CCRL2), is a non-signaling 7TM receptor, referred to as an atypical chemokine recep...
FEB 23, 2022 | 11:55 PM
The explosion of biomedical data such as in genomics, structure biology and pharmacology can provide new opportunities to improve our understanding of human physiology and disease. Understan...
FEB 23, 2022 | 11:55 PM
Adhesion G protein-coupled receptors (aGPCRs) are an ancient class of receptors that represent some of the largest transmembrane-integrated proteins in humans. Besides classic features of GP...
FEB 23, 2022 | 7:30 AM
Receptors that respond to hormones, neurotransmitters, chemokines and growth factors traffic to the cell surface where they are activated by ligands and signal via coupling to molecules such...
OCT 20, 2021 | 9:00 AM
Date: October 20, 2021 Time: 9:00am PDT Cryo-electron microscopy (cryo-EM) is rapidly evolving to be the primary tool for structure determination of membrane proteins. However, generation of...
JUN 15, 2021 | 10:00 AM
Date: June 15, 2021 Time: 10:00am (PDT), 1:00pm (EDT) SPRm (Surface Plasmon Resonance Microscopy) is a novel technology that enables label-free and real-time binding affinity and kinetics of...
MAY 11, 2021 | 10:00 AM
Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
MAR 16, 2021 | 10:00 AM
Date: March 16, 2021 Time: 10:00am (PST) Scientific progress and breakthroughs today are often too expensive for most institutions to acquire. Each year, the National Institutes of Health (N...
FEB 24, 2021 | 1:30 PM
G protein-coupled receptors (GPCRs) are among the most intensively studied drug targets, and account for about ~34% of all drugs approved by the FDA. Examples of drugs targeting GPCRs includ...
FEB 24, 2021 | 12:00 PM
Stable cell lines are critical tools of cellular assays in drug discovery and development. Over-expressing cell lines are needed to screen for hits, while functional cell lines are needed fo...
