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GPCR
GPCR: G-protein-coupled receptors (GPCRs) are the largest and most diverse group of membrane receptors in eukaryotes. These cell surface receptors act like an inbox for messages in the form of light energy, peptides, lipids, sugars, and proteins. Such messages inform cells about the presence or absence of life-sustaining light or nutrients in their environment, or they convey information sent by other cells.
MAY 10, 2017 | 4:00 AM
CALIXAR has developed an innovative detergent/surfactant based approach consisting on native isolation and stabilization of therapeutic membrane protein targets such as GPCRs, ion channels, t...
MAY 01, 2017 | 8:00 AM
Developing therapies for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficaciou...
APR 05, 2017 | 9:00 AM
G protein coupled receptors (GPCRs) are the targets of 30-40% of all approved drugs. However many approaches successfully applied to drug discovery for soluble protein targets have made a lim...
FEB 20, 2017 | 8:00 AM
Biosensors are now a well-established technology in the study of small molecules. This talk will focus on several aspects of this type of work that biosensor users can be expected to ex...
NOV 09, 2016 | 9:00 AM
DATE: November 9th, 2016
TIME: 9:00 AM PT, 12:00 PM ET
The screening and functional characterization of novel ligands for G-Protein Coupled Receptors (GPCR) remains a key focus in drug di...
OCT 11, 2016 | 7:00 AM
Date: October 11th, 2016Time: 10:00AM EST, 4:00PM CEST, 3:00PM BST, 7:00AM PSTPlate readers first became available about 30 years ago and have become the workhorses of researc...
SEP 16, 2015 | 5:00 AM
The antibiotic pipeline is broken, with a dearth of new antibiotics, a collapse in pharmaceutical company research1, and the exhaustion of chemical diversity contained in pharma libraries. "T...
