High throughput cell biology is the use of automation equipment with classical cell biology techniques to address biological questions that are otherwise unattainable using conventional methods. It may incorporate techniques from optics, chemistry, biology or image analysis to permit rapid, highly parallel research into how cells function, interact with each other and how pathogens exploit them in disease. High-throughput biology serves as one facet of what has also been called "omics research" - the interface between large scale biology (genome, proteome, transcriptome), technology and researchers. High throughput cell biology has a definite focus on the cell, and methods accessing the cell such as imaging, gene expression microarrays, or genome wide screening. The basic idea is to take methods normally performed on their own and do a very large number of them without impacting their quality.
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Dynamic changes in chromatin drive gene expression programs during cellular development and contribute to pathological changes underlying disease. To date, efforts to characterize chromatin...
Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
Patient-derived tumoroids, also known as cancer organoids, hold potential as cost-effective models for cancer immunotherapy research. Patient-derived tumor models, which mimic the tumor micr...
Epigenetic modifications such as DNA methylation have long shown promise as potential biomarkers to diagnose and guide treatment of many human diseases, including multiple types of cancers....
Organoids continue to gain traction in drug discovery efforts as they offer a more biologically relevant disease model than traditional approaches. But they aren't without challenges. Jo...
Preliminary data indicate the presence of inflammatory derangements in AML, necessitating a comprehensive examination of inflammatory effector cytokines involved in AML pathogenesis and ther...
Effective cellular therapies for solid tumors remain elusive. Advances in gene editing and synthetic biology offer great potential for improving the safety and functionality of engineered ce...
The multiplexing capability of tandem mass tags (TMT) has driven quantitative proteomic experimental designs towards larger numbers of samples. In order to efficiently process hundreds to th...
Advancements in Next Generation Sequencing (NGS) are changing the genomics industry, favoring those with scale. Quest Diagnostics' clinical expertise, combined with our infrastructure, p...
Antibiotic resistance is a global health threat and an emerging micropollutant of concern. Monitoring antibiotic resistance genes (ARGs) from environmental samples requires advanced molecula...
Genetically modified cell models accelerate the development of safe and effective therapeutics, making them indispensable in the quest for new drugs. Through manipulation of cell line geneti...
Feeding the world in the midst of climate change and an ever-growing population demands scientists have access to scalable, flexible and sustainable genomic tools that add value to animal br...
Achieving consistent AAV quantification with the QuantStudio Absolute Q AutoRun dPCR Suite Accurate quantification of AAV vectors is crucial for quality control and timely decision-making du...
Date: May 31, 2023 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CET) Single-cell genomics has facilitated the understanding of mechanisms involved in various biological processes such as tumor...
Affinite Instruments is a developer and supplier of SPR analysis instruments, related consumables, and software. Focusing on the mission of SPR for everyone, this webinar will review the ben...
The most common complaint cannabis producers have about their testing labs is that the turnaround time is too long. Without test results, they cannot package, label, or sell their product, w...
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