Monoclonal antibodies are antibodies that are made by identical immune cells that are all clones of a unique parent cell. Monoclonal antibodies can have monovalent affinity, in that they bind to the same epitope.
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Antibody-drug conjugates (ADCs) are transforming oncology by combining the precision of monoclonal antibodies with the potency of cytotoxic drugs. Yet, developing effective ADCs requires ove...
Bispecific antibodies (bsAbs) represent a versatile and increasingly important class of targeted therapeutics, designed to bind two distinct sites — either two different epitopes on th...
The discovery and optimization of antibodies, whether through traditional methods or with the assistance of artificial intelligence, necessitates rapid and reliable data generation. Here we...
Charge heterogeneity in monoclonal antibodies can negatively impact binding affinity and potency, so it is critical to ensure that individual charge variants of biotherapeutic molecules are...
The human antibody repertoire, or reactome, is a vast and dynamic network of antibody-antigen interactions that plays a crucial role in health and disease. Understanding the complexity of th...
With a comprehensive overview of the developments in immunotherapeutics, this webinar focuses on the utilization of B cells in the production of monoclonal antibodies (mAbs) comparing conven...
In light of the numerous US FDA-approved humanized monoclonal antibodies (mAbs) for cancer immunotherapy, it is surprising that the advancement of B-cell epitope vaccines designed to elicit...
APR 03, 2024 | 9:00 AM
C.E. CREDITS
Cultured mammalian cells, particularly Chinese hamster ovary (CHO) cells are widely used in the biotechnology industry for production of a wide range of therapeutics, predominantly monoclona...
Quantifying critical quality attributes accurately and precisely is an important aspect of regulatory compliance. There is greater demand to optimize processes by integrating advanced analyt...
MAR 20, 2024 | 9:00 AM
C.E. CREDITS
Nanovials are emerging as an accessible platform for performing single-cell functional screening leveraging standard instrumentation, such as flow cytometers and microfluidic single-cell seq...
Most FDA-approved therapeutic drugs target transmembrane proteins, yet the development of monoclonal antibodies for multi-transmembrane protein targets has been limited. Despite the abundanc...