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    Phenotypic Screening

    Phenotypic Screening: is a type of screening that is used in biological research and drug discovery which is utilized to identify substances like molecules, peptides for RNAi that can change the phenotype of a cell or an organism. Phenotypic screening has been highly employed in the discovery of new drugs.

    Webinars

    • FEB 22, 2023 | 7:30 AM
      Keynote Presentation: Molecular Pharmacology Profiling: the Precursor to Preclinical Development
      Keynote Presentation: Molecular Pharmacology Profiling: the Precursor...
      In general, once a receptor drug target has been validated for the treatment of a particular condition, either a high throughput screen is carried out to identify potential hits, or existing...
      Speaker: Professor Kevin Pfleger, MA, PhD, FBPhS
      Presented at: Drug Discovery & Development Virtual Event Series 2023
      2
      DEC 08, 2022 | 10:00 AM
      Re-think High Content Screening: Part 1 - Why old technology doesn't cut it in the new world
      Re-think High Content Screening: Part 1 - Why old technology doesn't...
      Date: November 08, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) In this webinar, scientists from Araceli Biosciences examine how high content screening (HCS) needs have changed in th...
      Speaker: Dr. Maggie Vantangoli Policelli
      Sponsored By: Araceli Biosciences
      11
      APR 26, 2022 | 7:00 AM
      High-Content Phenotypic Screening - Answering Questions You Haven't Even Asked Yet
      High-Content Phenotypic Screening - Answering Questions You Haven't...
      Date: April 19, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) High-content (HC) phenotypic profiling approaches are a powerful tool to study the effect of biological, genetic, and ch...
      Speaker: Dr. Angeline Lim , Dr. Victor Wong
      Sponsored By: Molecular Devices
      5
      JAN 20, 2022 | 11:00 AM
      How to streamline your variant classification workflow with HGMD
      How to streamline your variant classification workflow with HGMD
      Date: January 20, 2022 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CEST) The Human Gene Mutation Database (HGMD) is a one-of-a-kind resource containing data for hundreds of thousands of varia...
      Speaker: Malaina Gaddis, PhD
      Sponsored By: QIAGEN
      14
      DEC 02, 2021 | 8:00 AM
      Early identification of target candidates for pancreatic adenocarcinoma immunotherapy
      Early identification of target candidates for pancreatic adenocarcinoma...
      Date: December 2, 2021 Time: 8:00am (PDT), 11:00am (EDT) Effective immunotherapy of pancreatic ductal adenocarcinoma (PDAC) is hampered by the lack of suitable tumor-specific antigens. To ad...
      Speaker: Olaf Hardt, PhD
      Sponsored By: Miltenyi Biotec
      5
      OCT 26, 2021 | 9:00 AM
      Hemoglobinopathy Testing: What are the Key Points a Lab Should Consider?
      Hemoglobinopathy Testing: What are the Key Points a Lab Should...
      Date: October 26, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Capillary Electrophoresis plays an important role in the diagnosis of hemoglobinopathy carriers and patients. The general flow is the...
      Speaker: Dr. Cornelis Harteveld
      Sponsored By: Sebia, Inc.
      19
      OCT 06, 2021 | 10:30 AM
      Early Identification of Target Candidates for Pancreatic Adenocarcinoma Immunotherapy
      Early Identification of Target Candidates for Pancreatic Adenocarcinoma...
      Effective immunotherapy of pancreatic ductal adenocarcinoma (PDAC) is hampered by the lack of suitable tumor-specific antigens. To address this challenge, we have combined high-throughput fl...
      Speaker: Olaf Hardt, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2021
      Sponsored By: Miltenyi Biotec
      1
      AUG 25, 2021 | 10:30 AM
      Methods for Culturing Primary Adult CNS Neurons
      Methods for Culturing Primary Adult CNS Neurons
      In 1910, Harrison published the first report of frog embryonic sympathetic ganglia grown in hanging drops of lymph for a few days, where single neurons extended nerve fibers with complex gro...
      Speaker: Erna van Niekerk, Ph.D.
      Presented at: Neuroscience Virtual Event Series 2021
      Sponsored By: Miltenyi Biotec
      2
      JUL 29, 2021 | 9:00 AM
      Expanded Carrier Screening Research in the Genomic Era
      Expanded Carrier Screening Research in the Genomic Era
      Date: July 29, 2021 Time: 1:00am (PDT), 4:00am (EDT) Traditionally limited to a small number of phenotypes and mutations suggested to specific risk groups, the emerging field of genomics i...
      Speaker: Dr. Doron Behar, MD, PhD
      Sponsored By: Thermo Fisher Scientific
      7
      FEB 03, 2021 | 12:30 PM
      Optimizing High-Content Imaging of 3D Models for Drug Discovery
      Optimizing High-Content Imaging of 3D Models for Drug Discovery
      In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
      Speaker: Arvonn Tully , Judi Wardwell-Swanson
      Presented at: 7th Annual Conference: SBI2 High Content
      Sponsored By: SBI2, InSphero , Yokogawa
      11 10
      NOV 16, 2020 | 8:00 AM
      Targeted single-cell RNA sequencing enables genome-scale CRISPR screens
      Targeted single-cell RNA sequencing enables genome-scale CRISPR...
      Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
      Speaker: Wieland Keilholz, Ph.D. , Pawel Zajac, Ph.D. , Dr. Tilmann Buerckstuemmer
      Sponsored By: Illumina
      11
      SEP 30, 2020 | 10:30 AM
      Straightforward CRISPR knockout: Leveraging predesigned synthetic sgRNAs for highly functional and specific gene knockout
      Straightforward CRISPR knockout: Leveraging predesigned synthetic...
      CRISPR-based genome editing has accelerated biological research and holds great potential for studying and treating human diseases. The CRISPR-Cas9 system requires a Cas9 nuclease and a guid...
      Speaker: James Goldmeyer, PhD
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: Horizon Discovery
      3 1
      JUL 29, 2020 | 11:00 AM
      STAT3 phosphorylation during phagocytosis is required to activate autophagy and prevent macrophage immuno-senescence
      STAT3 phosphorylation during phagocytosis is required to activate...
      Background: Acute liver injury (ALI) is characterised by hepatocyte death and liver inflammation. Macrophages play a pivotal role in ALI by phagocytosing dead cells and producing pro-regener...
      Speaker: Lara Campana, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      2
      JUL 29, 2020 | 12:00 AM
      Phenotypic and MoA Analysis of Anti-Metastatic Molecules using 3D Tumoroid Invasion Assays, Kinetic Ligand Binding, and Cellular Microscopy
      Phenotypic and MoA Analysis of Anti-Metastatic Molecules using...
      Metastasis is the main cause of death in cancer patients and one of the most complex biological processes in human diseases (Hanahan et al., 2011). The development of therapies designed to f...
      Speaker: Brad Larson
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 02, 2020 | 1:30 PM
      Molecular Diagnosis of Genetic Diseases using CE in an era of different technologies
      Molecular Diagnosis of Genetic Diseases using CE in an era of...
      Genetic diseases are known occur due to various types of mutations in the human genome. The molecular assays to diagnose these diseases have been developed based on the type of mutation comm...
      Speaker: Ashwin Dalal, MD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      3
      JUN 30, 2020 | 9:00 AM
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
      DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
      Speaker: Jane Weitzel
      Sponsored By: Sartorius
      17 1
      JUN 30, 2020 | 8:00 AM
      Phenotyping the Tumor Microenvironment Using DNA Barcoded Multiplex Technology
      Phenotyping the Tumor Microenvironment Using DNA Barcoded Multiplex...
      DATE: June 30, 2020 TIME: 8:00am PT, 11:00am Understanding the tumor microenvironment (TME) is essential for the development of effective treatments for cancer patients. Traditional multi...
      Speaker: Chifei Sun
      Sponsored By: Leica Biosystems
      19
      JUN 03, 2020 | 8:00 AM
      Keynote Presentation: It is Time for TIME (Tumor Immune Microenvironment) in Experimental and Diagnostic Pathology
      Keynote Presentation: It is Time for TIME (Tumor Immune Microenvironment)...
      Cancer initiation and virulence depends on mechanisms to evade host immunosurveillance and suppression of early invasion and growth. Distinct phenotypes of the immune infiltrates in and arou...
      Speaker: Alexander David Borowsky, MD
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: Leica Biosystems
      1
      JUN 03, 2020 | 12:00 AM
      Microenvironment on Demand: A breakthrough technology for personalized cell therapy discoveries
      Microenvironment on Demand: A breakthrough technology for personalized...
      NCI estimates that cancer will be the leading cause of death in 2030, worldwide. Checkpoint inhibitors and adoptive cell therapies (ACTs) cost up to ~$2 million/patient and have shown durabl...
      Speaker: Maithreyan Srinivasan
      Presented at: Immuno-Oncology Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      Comprehensive Genomic Association Data for Genetic Variant Interpretation: A Computational Approach
      Comprehensive Genomic Association Data for Genetic Variant Interpretation:...
      Design and interpretation of genome sequencing assays and data in both clinical diagnostics and research labs is complicated by an inability to identify information from the medical literatu...
      Speaker: Mark Kiel, MD, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 12, 2020 | 9:00 AM
      Analytical Quality Control for the Pharmaceutical Industry
      Analytical Quality Control for the Pharmaceutical Industry
      NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
      Speaker: Joy McElroy
      Sponsored By: Sartorius
      29 9
      APR 30, 2020 | 9:00 AM
      Tools and methods for CRISPR-Cas9 screening for functional genomics and drug discovery
      Tools and methods for CRISPR-Cas9 screening for functional genomics...
      DATE: April 30, 2020 TIME: 9:00am PT, 12:00pm ET Loss-of-function studies are an established method for uncovering a gene’s role in a biological pathway or disease state. The advent of...
      Speaker: Louise Baskin, M.S. Molecular Biology and Genetics
      Sponsored By: Thermo Fisher Scientific
      23 1
      APR 24, 2020 | 8:00 AM
      The International Council for Standardisation in Hematology (ICSH) recommendations for Hemostasis Critical Values, Tests, and Reporting - a stepwise description for the committee's decisions
      The International Council for Standardisation in Hematology (ICSH)...
      The International Council for Standardization in Haematology (ICSH) is a nonprofit organization dedicated to providing open-access guidance documents to enhance the quality of laboratory tes...
      Speaker: Bob Gosselin
      Sponsored By: Diagnostica Stago, Inc.
      10
      APR 22, 2020 | 8:00 AM
      C.E. CREDITS
      The NEW Coag Value Playbook...Embrace the Power of Local Testing
      The NEW Coag Value Playbook...Embrace the Power of Local Testing
      Discover strategies for labs to optimize coagulation testing, improve patient outcomes, and strengthen their role in clinical care teams....
      Speaker: Eleanor Herriman, MD, MBA , Oksana Volod, MD
      Presented at: Stago EdVantage Virtual University
      Sponsored By: Diagnostica Stago, Inc.
      7
    FEB 22, 2023 | 7:30 AM
    Keynote Presentation: Molecular Pharmacology Profiling: the Precursor to Preclinical Development
    Keynote Presentation: Molecular Pharmacology Profiling: the Precursor...
    In general, once a receptor drug target has been validated for the treatment of a particular condition, either a high throughput screen is carried out to identify potential hits, or existing...
    Speaker: Professor Kevin Pfleger, MA, PhD, FBPhS
    Presented at: Drug Discovery & Development Virtual Event Series 2023
    2
    DEC 08, 2022 | 10:00 AM
    Re-think High Content Screening: Part 1 - Why old technology doesn't cut it in the new world
    Re-think High Content Screening: Part 1 - Why old technology doesn't...
    Date: November 08, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) In this webinar, scientists from Araceli Biosciences examine how high content screening (HCS) needs have changed in th...
    Speaker: Dr. Maggie Vantangoli Policelli
    Sponsored By: Araceli Biosciences
    11
    APR 26, 2022 | 7:00 AM
    High-Content Phenotypic Screening - Answering Questions You Haven't Even Asked Yet
    High-Content Phenotypic Screening - Answering Questions You Haven't...
    Date: April 19, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) High-content (HC) phenotypic profiling approaches are a powerful tool to study the effect of biological, genetic, and ch...
    Speaker: Dr. Angeline Lim , Dr. Victor Wong
    Sponsored By: Molecular Devices
    5
    JAN 20, 2022 | 11:00 AM
    How to streamline your variant classification workflow with HGMD
    How to streamline your variant classification workflow with HGMD
    Date: January 20, 2022 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CEST) The Human Gene Mutation Database (HGMD) is a one-of-a-kind resource containing data for hundreds of thousands of varia...
    Speaker: Malaina Gaddis, PhD
    Sponsored By: QIAGEN
    14
    DEC 02, 2021 | 8:00 AM
    Early identification of target candidates for pancreatic adenocarcinoma immunotherapy
    Early identification of target candidates for pancreatic adenocarcinoma...
    Date: December 2, 2021 Time: 8:00am (PDT), 11:00am (EDT) Effective immunotherapy of pancreatic ductal adenocarcinoma (PDAC) is hampered by the lack of suitable tumor-specific antigens. To ad...
    Speaker: Olaf Hardt, PhD
    Sponsored By: Miltenyi Biotec
    5
     
     
  • OCT 26, 2021 | 9:00 AM
    Hemoglobinopathy Testing: What are the Key Points a Lab Should Consider?
    Hemoglobinopathy Testing: What are the Key Points a Lab Should...
    Date: October 26, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Capillary Electrophoresis plays an important role in the diagnosis of hemoglobinopathy carriers and patients. The general flow is the...
    Speaker: Dr. Cornelis Harteveld
    Sponsored By: Sebia, Inc.
    19
    OCT 06, 2021 | 10:30 AM
    Early Identification of Target Candidates for Pancreatic Adenocarcinoma Immunotherapy
    Early Identification of Target Candidates for Pancreatic Adenocarcinoma...
    Effective immunotherapy of pancreatic ductal adenocarcinoma (PDAC) is hampered by the lack of suitable tumor-specific antigens. To address this challenge, we have combined high-throughput fl...
    Speaker: Olaf Hardt, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2021
    Sponsored By: Miltenyi Biotec
    1
    AUG 25, 2021 | 10:30 AM
    Methods for Culturing Primary Adult CNS Neurons
    Methods for Culturing Primary Adult CNS Neurons
    In 1910, Harrison published the first report of frog embryonic sympathetic ganglia grown in hanging drops of lymph for a few days, where single neurons extended nerve fibers with complex gro...
    Speaker: Erna van Niekerk, Ph.D.
    Presented at: Neuroscience Virtual Event Series 2021
    Sponsored By: Miltenyi Biotec
    2
    JUL 29, 2021 | 9:00 AM
    Expanded Carrier Screening Research in the Genomic Era
    Expanded Carrier Screening Research in the Genomic Era
    Date: July 29, 2021 Time: 1:00am (PDT), 4:00am (EDT) Traditionally limited to a small number of phenotypes and mutations suggested to specific risk groups, the emerging field of genomics i...
    Speaker: Dr. Doron Behar, MD, PhD
    Sponsored By: Thermo Fisher Scientific
    7
    FEB 03, 2021 | 12:30 PM
    Optimizing High-Content Imaging of 3D Models for Drug Discovery
    Optimizing High-Content Imaging of 3D Models for Drug Discovery
    In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
    Speaker: Arvonn Tully , Judi Wardwell-Swanson
    Presented at: 7th Annual Conference: SBI2 High Content
    Sponsored By: SBI2, InSphero , Yokogawa
    11 10
     
     
  • NOV 16, 2020 | 8:00 AM
    Targeted single-cell RNA sequencing enables genome-scale CRISPR screens
    Targeted single-cell RNA sequencing enables genome-scale CRISPR...
    Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
    Speaker: Wieland Keilholz, Ph.D. , Pawel Zajac, Ph.D. , Dr. Tilmann Buerckstuemmer
    Sponsored By: Illumina
    11
    SEP 30, 2020 | 10:30 AM
    Straightforward CRISPR knockout: Leveraging predesigned synthetic sgRNAs for highly functional and specific gene knockout
    Straightforward CRISPR knockout: Leveraging predesigned synthetic...
    CRISPR-based genome editing has accelerated biological research and holds great potential for studying and treating human diseases. The CRISPR-Cas9 system requires a Cas9 nuclease and a guid...
    Speaker: James Goldmeyer, PhD
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: Horizon Discovery
    3 1
    JUL 29, 2020 | 11:00 AM
    STAT3 phosphorylation during phagocytosis is required to activate autophagy and prevent macrophage immuno-senescence
    STAT3 phosphorylation during phagocytosis is required to activate...
    Background: Acute liver injury (ALI) is characterised by hepatocyte death and liver inflammation. Macrophages play a pivotal role in ALI by phagocytosing dead cells and producing pro-regener...
    Speaker: Lara Campana, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    2
    JUL 29, 2020 | 12:00 AM
    Phenotypic and MoA Analysis of Anti-Metastatic Molecules using 3D Tumoroid Invasion Assays, Kinetic Ligand Binding, and Cellular Microscopy
    Phenotypic and MoA Analysis of Anti-Metastatic Molecules using...
    Metastasis is the main cause of death in cancer patients and one of the most complex biological processes in human diseases (Hanahan et al., 2011). The development of therapies designed to f...
    Speaker: Brad Larson
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 02, 2020 | 1:30 PM
    Molecular Diagnosis of Genetic Diseases using CE in an era of different technologies
    Molecular Diagnosis of Genetic Diseases using CE in an era of...
    Genetic diseases are known occur due to various types of mutations in the human genome. The molecular assays to diagnose these diseases have been developed based on the type of mutation comm...
    Speaker: Ashwin Dalal, MD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    3
     
     
  • JUN 30, 2020 | 9:00 AM
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
    DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
    Speaker: Jane Weitzel
    Sponsored By: Sartorius
    17 1
    JUN 30, 2020 | 8:00 AM
    Phenotyping the Tumor Microenvironment Using DNA Barcoded Multiplex Technology
    Phenotyping the Tumor Microenvironment Using DNA Barcoded Multiplex...
    DATE: June 30, 2020 TIME: 8:00am PT, 11:00am Understanding the tumor microenvironment (TME) is essential for the development of effective treatments for cancer patients. Traditional multi...
    Speaker: Chifei Sun
    Sponsored By: Leica Biosystems
    19
    JUN 03, 2020 | 8:00 AM
    Keynote Presentation: It is Time for TIME (Tumor Immune Microenvironment) in Experimental and Diagnostic Pathology
    Keynote Presentation: It is Time for TIME (Tumor Immune Microenvironment)...
    Cancer initiation and virulence depends on mechanisms to evade host immunosurveillance and suppression of early invasion and growth. Distinct phenotypes of the immune infiltrates in and arou...
    Speaker: Alexander David Borowsky, MD
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: Leica Biosystems
    1
    JUN 03, 2020 | 12:00 AM
    Microenvironment on Demand: A breakthrough technology for personalized cell therapy discoveries
    Microenvironment on Demand: A breakthrough technology for personalized...
    NCI estimates that cancer will be the leading cause of death in 2030, worldwide. Checkpoint inhibitors and adoptive cell therapies (ACTs) cost up to ~$2 million/patient and have shown durabl...
    Speaker: Maithreyan Srinivasan
    Presented at: Immuno-Oncology Virtual Event Series 2020
    1
    MAY 20, 2020 | 12:00 AM
    Comprehensive Genomic Association Data for Genetic Variant Interpretation: A Computational Approach
    Comprehensive Genomic Association Data for Genetic Variant Interpretation:...
    Design and interpretation of genome sequencing assays and data in both clinical diagnostics and research labs is complicated by an inability to identify information from the medical literatu...
    Speaker: Mark Kiel, MD, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
     
     
  • MAY 12, 2020 | 9:00 AM
    Analytical Quality Control for the Pharmaceutical Industry
    Analytical Quality Control for the Pharmaceutical Industry
    NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
    Speaker: Joy McElroy
    Sponsored By: Sartorius
    29 9
    APR 30, 2020 | 9:00 AM
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    DATE: April 30, 2020 TIME: 9:00am PT, 12:00pm ET Loss-of-function studies are an established method for uncovering a gene’s role in a biological pathway or disease state. The advent of...
    Speaker: Louise Baskin, M.S. Molecular Biology and Genetics
    Sponsored By: Thermo Fisher Scientific
    23 1
    APR 24, 2020 | 8:00 AM
    The International Council for Standardisation in Hematology (ICSH) recommendations for Hemostasis Critical Values, Tests, and Reporting - a stepwise description for the committee's decisions
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    Speaker: Bob Gosselin
    Sponsored By: Diagnostica Stago, Inc.
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    APR 22, 2020 | 8:00 AM
    C.E. CREDITS
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    Speaker: Eleanor Herriman, MD, MBA , Oksana Volod, MD
    Presented at: Stago EdVantage Virtual University
    Sponsored By: Diagnostica Stago, Inc.
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