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    Research and Development

    Research and Development: innovative activities performed by corporations or governments for the creation, discovery and advancement of services and products.

    Webinars

    • FEB 05, 2014 | 9:00 AM
      The Manager of the Vivarium at the End of the World
      The Manager of the Vivarium at the End of the World
      The city of Valdivia is located in Chile, South America, 841 km south of its capital city Santiago. I moved to Valdivia early in 2004 to participate in the development of a new animal facilit...
      Speaker: Juan Manuel Baamonde
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      2
      FEB 01, 2014 | 8:00 AM
      Rapid, Accurate Exosome Purification and Sizing: High Performance Exosome Purification and Characterization via automated Density Gradient, Ultracentrifugation and Dynamic Light Scattering
      Rapid, Accurate Exosome Purification and Sizing: High Performance...
      Abstract: •General background, diagnostic and bio-marker implications of exosomes research •Current solutions to purifying and identifying exosomes rapidly and accurately •R...
      Speaker: Joshua Robinson
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      0
      NOV 20, 2013 | 11:00 AM
      Tools to accelerate biomarker screening for CDx
      Tools to accelerate biomarker screening for CDx
      ...
      Speaker: Dan Rhodes, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Fall
      199
      NOV 20, 2013 | 10:00 AM
      Navigating the Evolving Molecular Diagnostic Reimbursement Landscape to Optimize Coverage and Payment and Identify Opportunities
      Navigating the Evolving Molecular Diagnostic Reimbursement Landscape...
      2013 has proven to be a year of paradigmatic shifts in molecular diagnostics reimbursement policy. In this session, we will review and analyze these key policy and payment developments and di...
      Speaker: Nicole Littmann
      Presented at: Advanced Genomics in Clinical and Translational Research - Fall
      50
      NOV 20, 2013 | 8:00 AM
      A comparison of genotyping platforms for pharmacogenetic testing
      A comparison of genotyping platforms for pharmacogenetic testing
      As the scientific evidence base for pharmacogenetics continues to expand, the use of such information in clinical management and drug development will be in demand. The FDA advises that the...
      Speaker: Mark Borgman, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Fall
      210
      NOV 08, 2013 | 12:00 PM
      Childhood cancer with various genomic assay including whole genome sequencing
      Childhood cancer with various genomic assay including whole genome...
      The NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) is a comprehensive genomic characterization initiative to determine the molecular changes that drive th...
      Speaker: Jaime Guidry Auvil, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      4
      OCT 23, 2013 | 12:00 PM
      Cellular regulation of the molecular chaperone HSP90 by posttranslational modifications - impact on function and drug sensitivity
      Cellular regulation of the molecular chaperone HSP90 by posttranslational...
      Molecular chaperones help nascent polypeptides fold correctly and multimeric protein complexes assemble productively, while minimizing the danger of aggregation in the protein-rich intracellu...
      Speaker: Len Neckers, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      2
      OCT 17, 2013 | 3:00 PM
      C.E. CREDITS
      From Genomic Questions to Clinical Answers in Cancer
      From Genomic Questions to Clinical Answers in Cancer
      Although genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) associated with cancer, the contribution to risk of these variants is small, rende...
      Speaker: Kenan Onel MD, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      46
      OCT 17, 2013 | 2:00 PM
      C.E. CREDITS
      Oncoproteins K-Ras and Pim kinases as molecular targets in pancreatic cancer
      Oncoproteins K-Ras and Pim kinases as molecular targets in pancreatic...
      Pancreatic cancer is the 4th most common cause of cancer deaths in the United States. Due to the aggressive nature of this cancer and the lack of biomarkers for early detection, the incidence...
      Speaker: Antonio T. Baines, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      73
      OCT 17, 2013 | 12:00 PM
      Biomarkers & Dx test development
      Biomarkers & Dx test development
      The discovery of proteinaceous disease biomarkers and their clinical validation is critically important for the enablement of molecular diagnostics and ultimately, precision medicine. In spit...
      Speaker: Martin Latterich, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      36
      OCT 17, 2013 | 12:00 PM
      C.E. CREDITS
      Embracing the Complexity of Cancer: Seeing the Forest and the Trees
      Embracing the Complexity of Cancer: Seeing the Forest and the...
      Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      34
      OCT 17, 2013 | 11:00 AM
      C.E. CREDITS
      The Need for Critical Reassessment of Current Strategies for Cancer Therapeutics.
      The Need for Critical Reassessment of Current Strategies for Cancer...
      Curative therapy for metastatic disease in solid malignancies remains frustratingly elusive due to the long recognized problem of tumor cell heterogeneity and emergence of treatment resistant...
      Speaker: George Poste, DVM, DSc, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      42
      OCT 17, 2013 | 10:00 AM
      C.E. CREDITS
      The Molecular Mechanisms of Castration-Resistant Prostate Cancer
      The Molecular Mechanisms of Castration-Resistant Prostate Cancer
      Prostate cancer epithelial cells depend on androgens for their survival. Because of this dependence, androgen deprivation therapy is the major treatment of advanced prostate cancer. Such ther...
      Speaker: Donald Tindall, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      40
      OCT 17, 2013 | 9:00 AM
      C.E. CREDITS
      Subtyping Circulating Tumor Cells in Breast Cancer for Personalized Therapeutics
      Subtyping Circulating Tumor Cells in Breast Cancer for Personalized...
      Cancer metastases develop when tumor cells known as circulating tumor cells (CTCs) are shed from a tumor, circulate through the blood stream and colonize a distant tissue. The number of CTCs...
      Speaker: Lori M. Millner, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      86
      OCT 17, 2013 | 8:00 AM
      Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy
      Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy
      Many drugs currently used for anti-cancer therapy demonstrate significant inter-individual variability that cannot be normalized using body weight or body surface area. There is an increasing...
      Speaker: William Clarke, PhD, MBA, DABCC
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      264
      OCT 17, 2013 | 8:00 AM
      C.E. CREDITS
      Next-generation Cancer Care in the Age of Genomics, Precision Medicine, High Throughput Biology
      Next-generation Cancer Care in the Age of Genomics, Precision...
      Developments in DNA sequencing technology have provided a unique opportunity for diagnosis and discovery of genetic alterations for rare diseases. Partnering with 20 academic centers in the U...
      Speaker: C Jimmy Lin, MD, PhD, MHS
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      52
      OCT 17, 2013 | 7:00 AM
      C.E. CREDITS
      Monitoring for Chemotherapy Toxicity and Cardiac Troponin
      Monitoring for Chemotherapy Toxicity and Cardiac Troponin
      Recent data have confirmed the ability of cardiac troponin (cTn) measurements to identify those who are developing cardiotoxicity in response to potentially cardiotoxic chemotherapeutic agen...
      Speaker: Allan Jaffe, M.D.
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      32
      OCT 17, 2013 | 7:00 AM
      Noninvasive Cancer Genomics
      Noninvasive Cancer Genomics
      Whenever there is cell death, apoptotic cell free DNA fragments appear in the circulation of the host. These fragments, typically 145-160 base pairs in size, represent a minute fraction of to...
      Speaker: Charles Cantor, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      50
      OCT 17, 2013 | 7:00 AM
      Advancing Translational Cancer Research through Automated RNASeq Sample Preparation from Archival FFPE Tissue Specimens
      Advancing Translational Cancer Research through Automated RNASeq...
      RNA-Seq allows the simultaneous observation of gene expression levels, mutations in the coding sequences, splice variants and gene fusions, which are especially important in cancer studies. A...
      Speaker: Michaela Bowden, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      98
      OCT 17, 2013 | 6:00 AM
      A Bioinformatics Approach to Clinical Sequencing
      A Bioinformatics Approach to Clinical Sequencing
      The widespread adoption of precision medicine in oncology requires: a compendium of therapies targeting the genetic vulnerabilities of cancer; the diagnostic tools capable of generating a pr...
      Speaker: Dan Rhodes, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      80
      OCT 16, 2013 | 3:00 PM
      C.E. CREDITS
      Recent Developments in the treatment of Melanoma
      Recent Developments in the treatment of Melanoma
      While Melanoma is very curable and treatable when detected early, late stage melanoma has had a very poor outcome. In 2013, it is estimated that over 80,000 patients in the US will develop me...
      Speaker: Adil Daud, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      36
      OCT 16, 2013 | 2:00 PM
      C.E. CREDITS
      Novel therapies for ALK mutated cancers
      Novel therapies for ALK mutated cancers
      Non Small Cell Lung Cancer (NSCLC) is one of the most significant causes of cancer-related mortality worldwide. In about 6-7% of NSCLC, rearrangements involving the Anaplastic Lymphoma Kinase...
      Speaker: Roberto Chiarle, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      32
      OCT 16, 2013 | 1:00 PM
      C.E. CREDITS
      Investigating tissue specificity of cancer-causing germline mutations
      Investigating tissue specificity of cancer-causing germline mutations
      The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
      Speaker: Jessica C. Mar, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      68
      OCT 16, 2013 | 1:00 PM
      C.E. CREDITS
      Resistance to AR Signaling Inhibitors in Castration Resistant Prostate Cancer
      Resistance to AR Signaling Inhibitors in Castration Resistant...
      While androgen deprivation therapy (ADT) remains the primary treatment modality for patients with metastatic prostate cancer (PCa), treatment is uniformly marked by progression to castration-...
      Speaker: Elahe A Mostaghel, MD, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      80
    FEB 05, 2014 | 9:00 AM
    The Manager of the Vivarium at the End of the World
    The Manager of the Vivarium at the End of the World
    The city of Valdivia is located in Chile, South America, 841 km south of its capital city Santiago. I moved to Valdivia early in 2004 to participate in the development of a new animal facilit...
    Speaker: Juan Manuel Baamonde
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    2
    FEB 01, 2014 | 8:00 AM
    Rapid, Accurate Exosome Purification and Sizing: High Performance Exosome Purification and Characterization via automated Density Gradient, Ultracentrifugation and Dynamic Light Scattering
    Rapid, Accurate Exosome Purification and Sizing: High Performance...
    Abstract: •General background, diagnostic and bio-marker implications of exosomes research •Current solutions to purifying and identifying exosomes rapidly and accurately •R...
    Speaker: Joshua Robinson
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    0
    NOV 20, 2013 | 11:00 AM
    Tools to accelerate biomarker screening for CDx
    Tools to accelerate biomarker screening for CDx
    ...
    Speaker: Dan Rhodes, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Fall
    199
    NOV 20, 2013 | 10:00 AM
    Navigating the Evolving Molecular Diagnostic Reimbursement Landscape to Optimize Coverage and Payment and Identify Opportunities
    Navigating the Evolving Molecular Diagnostic Reimbursement Landscape...
    2013 has proven to be a year of paradigmatic shifts in molecular diagnostics reimbursement policy. In this session, we will review and analyze these key policy and payment developments and di...
    Speaker: Nicole Littmann
    Presented at: Advanced Genomics in Clinical and Translational Research - Fall
    50
    NOV 20, 2013 | 8:00 AM
    A comparison of genotyping platforms for pharmacogenetic testing
    A comparison of genotyping platforms for pharmacogenetic testing
    As the scientific evidence base for pharmacogenetics continues to expand, the use of such information in clinical management and drug development will be in demand. The FDA advises that the...
    Speaker: Mark Borgman, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Fall
    210
     
     
  • NOV 08, 2013 | 12:00 PM
    Childhood cancer with various genomic assay including whole genome sequencing
    Childhood cancer with various genomic assay including whole genome...
    The NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) is a comprehensive genomic characterization initiative to determine the molecular changes that drive th...
    Speaker: Jaime Guidry Auvil, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    4
    OCT 23, 2013 | 12:00 PM
    Cellular regulation of the molecular chaperone HSP90 by posttranslational modifications - impact on function and drug sensitivity
    Cellular regulation of the molecular chaperone HSP90 by posttranslational...
    Molecular chaperones help nascent polypeptides fold correctly and multimeric protein complexes assemble productively, while minimizing the danger of aggregation in the protein-rich intracellu...
    Speaker: Len Neckers, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    2
    OCT 17, 2013 | 3:00 PM
    C.E. CREDITS
    From Genomic Questions to Clinical Answers in Cancer
    From Genomic Questions to Clinical Answers in Cancer
    Although genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) associated with cancer, the contribution to risk of these variants is small, rende...
    Speaker: Kenan Onel MD, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    46
    OCT 17, 2013 | 2:00 PM
    C.E. CREDITS
    Oncoproteins K-Ras and Pim kinases as molecular targets in pancreatic cancer
    Oncoproteins K-Ras and Pim kinases as molecular targets in pancreatic...
    Pancreatic cancer is the 4th most common cause of cancer deaths in the United States. Due to the aggressive nature of this cancer and the lack of biomarkers for early detection, the incidence...
    Speaker: Antonio T. Baines, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    73
    OCT 17, 2013 | 12:00 PM
    Biomarkers & Dx test development
    Biomarkers & Dx test development
    The discovery of proteinaceous disease biomarkers and their clinical validation is critically important for the enablement of molecular diagnostics and ultimately, precision medicine. In spit...
    Speaker: Martin Latterich, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    36
     
     
  • OCT 17, 2013 | 12:00 PM
    C.E. CREDITS
    Embracing the Complexity of Cancer: Seeing the Forest and the Trees
    Embracing the Complexity of Cancer: Seeing the Forest and the...
    Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    34
    OCT 17, 2013 | 11:00 AM
    C.E. CREDITS
    The Need for Critical Reassessment of Current Strategies for Cancer Therapeutics.
    The Need for Critical Reassessment of Current Strategies for Cancer...
    Curative therapy for metastatic disease in solid malignancies remains frustratingly elusive due to the long recognized problem of tumor cell heterogeneity and emergence of treatment resistant...
    Speaker: George Poste, DVM, DSc, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    42
    OCT 17, 2013 | 10:00 AM
    C.E. CREDITS
    The Molecular Mechanisms of Castration-Resistant Prostate Cancer
    The Molecular Mechanisms of Castration-Resistant Prostate Cancer
    Prostate cancer epithelial cells depend on androgens for their survival. Because of this dependence, androgen deprivation therapy is the major treatment of advanced prostate cancer. Such ther...
    Speaker: Donald Tindall, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    40
    OCT 17, 2013 | 9:00 AM
    C.E. CREDITS
    Subtyping Circulating Tumor Cells in Breast Cancer for Personalized Therapeutics
    Subtyping Circulating Tumor Cells in Breast Cancer for Personalized...
    Cancer metastases develop when tumor cells known as circulating tumor cells (CTCs) are shed from a tumor, circulate through the blood stream and colonize a distant tissue. The number of CTCs...
    Speaker: Lori M. Millner, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    86
    OCT 17, 2013 | 8:00 AM
    Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy
    Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy
    Many drugs currently used for anti-cancer therapy demonstrate significant inter-individual variability that cannot be normalized using body weight or body surface area. There is an increasing...
    Speaker: William Clarke, PhD, MBA, DABCC
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    264
     
     
  • OCT 17, 2013 | 8:00 AM
    C.E. CREDITS
    Next-generation Cancer Care in the Age of Genomics, Precision Medicine, High Throughput Biology
    Next-generation Cancer Care in the Age of Genomics, Precision...
    Developments in DNA sequencing technology have provided a unique opportunity for diagnosis and discovery of genetic alterations for rare diseases. Partnering with 20 academic centers in the U...
    Speaker: C Jimmy Lin, MD, PhD, MHS
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    52
    OCT 17, 2013 | 7:00 AM
    C.E. CREDITS
    Monitoring for Chemotherapy Toxicity and Cardiac Troponin
    Monitoring for Chemotherapy Toxicity and Cardiac Troponin
    Recent data have confirmed the ability of cardiac troponin (cTn) measurements to identify those who are developing cardiotoxicity in response to potentially cardiotoxic chemotherapeutic agen...
    Speaker: Allan Jaffe, M.D.
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    32
    OCT 17, 2013 | 7:00 AM
    Noninvasive Cancer Genomics
    Noninvasive Cancer Genomics
    Whenever there is cell death, apoptotic cell free DNA fragments appear in the circulation of the host. These fragments, typically 145-160 base pairs in size, represent a minute fraction of to...
    Speaker: Charles Cantor, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    50
    OCT 17, 2013 | 7:00 AM
    Advancing Translational Cancer Research through Automated RNASeq Sample Preparation from Archival FFPE Tissue Specimens
    Advancing Translational Cancer Research through Automated RNASeq...
    RNA-Seq allows the simultaneous observation of gene expression levels, mutations in the coding sequences, splice variants and gene fusions, which are especially important in cancer studies. A...
    Speaker: Michaela Bowden, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    98
    OCT 17, 2013 | 6:00 AM
    A Bioinformatics Approach to Clinical Sequencing
    A Bioinformatics Approach to Clinical Sequencing
    The widespread adoption of precision medicine in oncology requires: a compendium of therapies targeting the genetic vulnerabilities of cancer; the diagnostic tools capable of generating a pr...
    Speaker: Dan Rhodes, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    80
     
     
  • OCT 16, 2013 | 3:00 PM
    C.E. CREDITS
    Recent Developments in the treatment of Melanoma
    Recent Developments in the treatment of Melanoma
    While Melanoma is very curable and treatable when detected early, late stage melanoma has had a very poor outcome. In 2013, it is estimated that over 80,000 patients in the US will develop me...
    Speaker: Adil Daud, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    36
    OCT 16, 2013 | 2:00 PM
    C.E. CREDITS
    Novel therapies for ALK mutated cancers
    Novel therapies for ALK mutated cancers
    Non Small Cell Lung Cancer (NSCLC) is one of the most significant causes of cancer-related mortality worldwide. In about 6-7% of NSCLC, rearrangements involving the Anaplastic Lymphoma Kinase...
    Speaker: Roberto Chiarle, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    32
    OCT 16, 2013 | 1:00 PM
    C.E. CREDITS
    Investigating tissue specificity of cancer-causing germline mutations
    Investigating tissue specificity of cancer-causing germline mutations
    The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
    Speaker: Jessica C. Mar, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    68
    OCT 16, 2013 | 1:00 PM
    C.E. CREDITS
    Resistance to AR Signaling Inhibitors in Castration Resistant Prostate Cancer
    Resistance to AR Signaling Inhibitors in Castration Resistant...
    While androgen deprivation therapy (ADT) remains the primary treatment modality for patients with metastatic prostate cancer (PCa), treatment is uniformly marked by progression to castration-...
    Speaker: Elahe A Mostaghel, MD, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    80
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