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    Single-Molecule

    Single-Molecule methods provide access to details of a population's characteristics that are obscured by ensemble averaging. It is a powerful method used to examine a multitude of phenomena using advanced techniques such as total internal reflection (TIRF) and superresolution imaging.

    Webinars

    • DEC 03, 2025 | 11:00 AM
      Versatility of mass photometry for the structural characterization of biomolecular assemblies present in blood
      Versatility of mass photometry for the structural characterization...
      In this webinar recent applications of mass photometry are highlighted especially focusing on higher-order protein assemblies as present in our blood. In particular, the ability of mass phot...
      Speaker: Albert Heck
      Sponsored By: Refeyn
      3
      SEP 17, 2025 | 8:00 AM
      Mass Photometry sheds light on the binding mechanism of the bispecific tetravalent anti-VEGF-PD-1 antibody Ivonescimab
      Mass Photometry sheds light on the binding mechanism of the bispecific...
      Ivonescimab is a that simultaneously targets programmed cell death protein 1 (PD-1) and vascular endothelial growth factor (VEGF), two key molecules in the tumour microenvironment. It's...
      Speaker: Dr. Nina Jajcanin Jozic
      Sponsored By: Refeyn
      9
      JUL 15, 2025 | 9:00 AM
      Investigating cell surface receptor dimerization using single-molecule super-resolution microscopy
      Investigating cell surface receptor dimerization using single-molecule...
      Explore how super-resolution microscopy reveals GPCR and RTK receptor dimerization, with a focus on D2 dopamine receptor function and disease relevance....
      Speaker: Katie Sharrocks
      Sponsored By: Thermo Fisher Scientific/Gibco
      9
      FEB 11, 2025 | 7:00 AM
      Single Molecule Light Field Microscopy, a Revolution in 3D Detection
      Single Molecule Light Field Microscopy, a Revolution in 3D Detection
      Light field microscopy (LFM) is a revolutionary technique first introduced in 2006 which can essentially capture a 3D volume in a single snapshot, complete with digital refocusing and deconv...
      Speaker: Matthew Kose-Dunn , Jeremy Graham , Prof. Steven Lee , Dr. Sam Daly
      Sponsored By: Teledyne Photometrics
      21
      DEC 10, 2024 | 9:00 AM
      Expanding Proteomic Horizons with Single-Molecule Proteome Analysis
      Expanding Proteomic Horizons with Single-Molecule Proteome Analysis
      To-date, proteomic analysis has been severely limited in scale and resolution. Analyzing protein samples using an intact, single-molecule approach holds th...
      Speaker: Parag Mallick, Ph.D.
      Sponsored By: Nautilus Biotechnology
      21
      On Demand
      C.E. CREDITS
      AI Analysis of Super-Resolution Microscopy: Novel Insight Into Subcellular Structure
      AI Analysis of Super-Resolution Microscopy: Novel Insight Into...
      Super-resolution microscopy, or nanoscopy, enables the use of fluorescent-based molecular localization tools to study molecular structure at the nanoscale level in the intact cell. Analysis...
      Speaker: Dr. Ivan Robert Nabi, PhD
      Presented at: Cell Biology Virtual Event Series 2024
      6
      AUG 29, 2024 | 10:00 AM
      Deep Dive into Spatial Biology with MERFISH Technology and the MERSCOPE Ultra Platformâ„¢
      Deep Dive into Spatial Biology with MERFISH Technology and the...
      In this presentation, Vizgen’s Instrument Product Manager will introduce you to their latest platform, the MERSCOPE® Ultra, for in situ spatial genomics powered by MERFISH technolo...
      Speaker: Rob Mathis , Manisha Ray, PhD
      Sponsored By: Vizgen
      10
      MAY 08, 2024 | 8:00 AM
      Expand your Multiomic Capabilities with RNAscopeâ„¢
      Expand your Multiomic Capabilities with RNAscopeâ„¢
      In this webinar we will provide an overview of RNAscope™ ISH technology, then discuss our new RNAscope multiomic applications coming soon. RNAscope is the gold standard for RNA ISH -pr...
      Speaker: Blake McAlpin, PhD , Paul Liu, Ph.D.
      Sponsored By: Leica Biosystems
      12
      MAR 27, 2024 | 9:00 AM
      PART 1: Utilizing the 6-base genome to investigate the dynamics of enhancer DNA methylation during cellular differentiation
      PART 1: Utilizing the 6-base genome to investigate the dynamics...
      Join Dr. Emily Hodges, assistant professor of biochemistry at Vanderbilt University, to learn more about how the Hodges Lab is utilizing the 6-base genome to investigate the dynamics of enha...
      Speaker: Dr. Emily Hodges
      Sponsored By: biomodal
      11
      MAR 26, 2024 | 9:00 AM
      Expanding Proteomic Horizons with Single-Molecule Proteome and Proteoform Analysis
      Expanding Proteomic Horizons with Single-Molecule Proteome and...
      The field of proteomics is undergoing a revolution to better quantify proteins and unlock the dynamic and valuable source of functional biological insight held in the proteome. Single-molecu...
      Speaker: Parag Mallick, Ph.D. , Andreas Hühmer, Ph.D.
      Sponsored By: Nautilus Biotechnology
      9
      MAR 20, 2024 | 8:00 AM
      Introducing the first dual reporter application for Luminex xMAP INTELLIFLEX DR-SE Instruments:  measurement of phosphorylated and total proteins on the same bead
      Introducing the first dual reporter application for Luminex xMAP...
      Luminex and Thermo Fisher Scientific are excited to feature two presentations highlighting the advanced features of the Invitrogen™ Luminex® xMAP® INTELLIFLEX™ DR-SE inst...
      Speaker: Sherry Dunbar, Ph.D., MBA , Sigrun Badrnya, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      11
      On Demand
      C.E. CREDITS
      Visualizing Protein Aggregates at the Single-Molecule Level
      Visualizing Protein Aggregates at the Single-Molecule Level
      Protein misfolding and aggregation are key features observed in numerous neurodegenerative conditions, such as Alzheimer's and Parkinson's disease. The oligomers formed during the ag...
      Speaker: Mathew H. Horrocks, PhD
      Presented at: Neuroscience Virtual Event Series 2024
      3
      On Demand
      C.E. CREDITS
      Picodroplets Enabling High Throughput Single Cell Screening and Isolation
      Picodroplets Enabling High Throughput Single Cell Screening and...
      The study of a single cell, the fundamental unit of our complex bodies, has become an important field in cellular biology, and researchers are using single-cell analysis to shed new light on...
      Speaker: Romina Durigon, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2024
      4
      NOV 01, 2023 | 7:30 AM
      Keynote Presentation: Microfluidics and CRISPR-Diagnostics/Therapy with Live Q&A
      Keynote Presentation: Microfluidics and CRISPR-Diagnostics/Therapy...
      Coronavirus Disease 2019 (COVID-19) has driven the use of nucleic acid testing technology in clinical testing. There is a growing need for point-of-care testing (POCT)......
      Speaker: Xingyu Jiang, PhD
      Presented at: CRISPR Virtual Event Series 2023
      1
      On Demand
      Multifaceted Community Analyses Uncover Novel Bacterial Species in the Colorectal Tumor Niche
      Multifaceted Community Analyses Uncover Novel Bacterial Species...
      The tumor-associated microbiota is an inherent component of the tumor microenvironment across various human cancer types1. Although members of tumor-associated microbiomes can be identified...
      Speaker: Martha Zepeda Rivera, PhD
      Presented at: Cancer Research & Immuno-Oncology Week Virtual Event Series 2023
      3
      SEP 12, 2023 | 8:00 AM
      Cell-based SPR Microscopy application in drug discovery
      Cell-based SPR Microscopy application in drug discovery
      SPRm (Surface Plasmon Resonance Microscopy) is a novel technology that enables label-free and real-time measurements of the binding affinity and kinetics of small molecules to G protein-coup...
      Speaker: Dr. Shijie Wu , Dr. Marie-Laure Rives
      Sponsored By: Biosensing Instrument
      12
      On-Demand
      Multifaceted Community Analyses Uncover Novel Bacterial Species in the Colorectal Tumor Niche
      Multifaceted Community Analyses Uncover Novel Bacterial Species...
      The tumor-associated microbiota is an inherent component of the tumor microenvironment across various human cancer types1. Although members of tumor-associated microbiomes can be identified t...
      Speaker: Martha Zepeda Rivera, PhD
      Presented at: Microbiology Week Virtual Event Series 2023
      2
      JUN 15, 2023 | 9:00 AM
      Empowering next-generation therapy development with electrophoresis technology and streamlined data integration
      Empowering next-generation therapy development with electrophoresis...
      Advancements in protein and gene therapy research have led to more complex modalities being developed. In addition, the desire for a deeper understanding of these molecules enhances the need...
      Speaker: Philip Hoang
      Sponsored By: SCIEX
      12
      MAY 16, 2023 | 8:00 AM
      Multivalent RNA CAR-T cell for malignant glioma
      Multivalent RNA CAR-T cell for malignant glioma
      The therapeutic use of chimeric antigen receptor T cells has achieved significant success in the treatment of B cells malignancies. Despite promising results in mouse tumor models, a similar...
      Speaker: Prof. Denis Migliorini
      Sponsored By: MaxCyte®
      13
      MAY 16, 2023 | 5:30 AM
      Sequencing Single-Strand Mismatch and Damage Patterns by Long-Read Sequencing
      Sequencing Single-Strand Mismatch and Damage Patterns by Long-Read...
      Mutations accumulate in the genome of every cell of the body throughout life, causing cancer and other genetic diseases....
      Speaker: Gilad Evrony, MD, PhD
      Presented at: Genetics Week Virtual Event Series 2023
      2
      MAR 16, 2023 | 8:00 AM
      Studying protein polymerization with mass photometry
      Studying protein polymerization with mass photometry
      Date: March 16, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Protein polymerization underpins major biological processes, such as cell division and intracellular transport, while und...
      Speaker: Nikolas Hundt
      Sponsored By: Refeyn
      20
      FEB 22, 2023 | 10:30 AM
      Using Single B Technology to Develop Lead Antibody Molecules on GPCR Targets with Live Q&A
      Using Single B Technology to Develop Lead Antibody Molecules on...
      Immunogens with native conformation and a high-throughput IgG cloning platform are two of the most important key components for high quality lead antibody molecules discovery. DIMABIO’...
      Speaker: Donghui Ma, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2023
      Sponsored By: DIMA Biotech
      3
      FEB 22, 2023 | 5:30 AM
      Novel Bioassays in Picodroplets for Single-Cell Analysis
      Novel Bioassays in Picodroplets for Single-Cell Analysis
      Many current technologies used in drug discovery and preclinical development programmes typically involve multi-step operations, extensive hands-on time, and lengthy liquid handling processe...
      Speaker: Romina Durigon, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2023
      2
      FEB 15, 2023 | 7:00 AM
      Scattering Microscopy: Label-Free Imaging Approaches
      Scattering Microscopy: Label-Free Imaging Approaches
      Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
      Speaker: Philipp Kukura , Francesco Reina , Matthew Kose-Dunn , Phil Allen
      Sponsored By: Teledyne Photometrics
      28
    DEC 03, 2025 | 11:00 AM
    Versatility of mass photometry for the structural characterization of biomolecular assemblies present in blood
    Versatility of mass photometry for the structural characterization...
    In this webinar recent applications of mass photometry are highlighted especially focusing on higher-order protein assemblies as present in our blood. In particular, the ability of mass phot...
    Speaker: Albert Heck
    Sponsored By: Refeyn
    3
    SEP 17, 2025 | 8:00 AM
    Mass Photometry sheds light on the binding mechanism of the bispecific tetravalent anti-VEGF-PD-1 antibody Ivonescimab
    Mass Photometry sheds light on the binding mechanism of the bispecific...
    Ivonescimab is a that simultaneously targets programmed cell death protein 1 (PD-1) and vascular endothelial growth factor (VEGF), two key molecules in the tumour microenvironment. It's...
    Speaker: Dr. Nina Jajcanin Jozic
    Sponsored By: Refeyn
    9
    JUL 15, 2025 | 9:00 AM
    Investigating cell surface receptor dimerization using single-molecule super-resolution microscopy
    Investigating cell surface receptor dimerization using single-molecule...
    Explore how super-resolution microscopy reveals GPCR and RTK receptor dimerization, with a focus on D2 dopamine receptor function and disease relevance....
    Speaker: Katie Sharrocks
    Sponsored By: Thermo Fisher Scientific/Gibco
    9
    FEB 11, 2025 | 7:00 AM
    Single Molecule Light Field Microscopy, a Revolution in 3D Detection
    Single Molecule Light Field Microscopy, a Revolution in 3D Detection
    Light field microscopy (LFM) is a revolutionary technique first introduced in 2006 which can essentially capture a 3D volume in a single snapshot, complete with digital refocusing and deconv...
    Speaker: Matthew Kose-Dunn , Jeremy Graham , Prof. Steven Lee , Dr. Sam Daly
    Sponsored By: Teledyne Photometrics
    21
    DEC 10, 2024 | 9:00 AM
    Expanding Proteomic Horizons with Single-Molecule Proteome Analysis
    Expanding Proteomic Horizons with Single-Molecule Proteome Analysis
    To-date, proteomic analysis has been severely limited in scale and resolution. Analyzing protein samples using an intact, single-molecule approach holds th...
    Speaker: Parag Mallick, Ph.D.
    Sponsored By: Nautilus Biotechnology
    21
     
     
  • On Demand
    C.E. CREDITS
    AI Analysis of Super-Resolution Microscopy: Novel Insight Into Subcellular Structure
    AI Analysis of Super-Resolution Microscopy: Novel Insight Into...
    Super-resolution microscopy, or nanoscopy, enables the use of fluorescent-based molecular localization tools to study molecular structure at the nanoscale level in the intact cell. Analysis...
    Speaker: Dr. Ivan Robert Nabi, PhD
    Presented at: Cell Biology Virtual Event Series 2024
    6
    AUG 29, 2024 | 10:00 AM
    Deep Dive into Spatial Biology with MERFISH Technology and the MERSCOPE Ultra Platformâ„¢
    Deep Dive into Spatial Biology with MERFISH Technology and the...
    In this presentation, Vizgen’s Instrument Product Manager will introduce you to their latest platform, the MERSCOPE® Ultra, for in situ spatial genomics powered by MERFISH technolo...
    Speaker: Rob Mathis , Manisha Ray, PhD
    Sponsored By: Vizgen
    10
    MAY 08, 2024 | 8:00 AM
    Expand your Multiomic Capabilities with RNAscopeâ„¢
    Expand your Multiomic Capabilities with RNAscopeâ„¢
    In this webinar we will provide an overview of RNAscope™ ISH technology, then discuss our new RNAscope multiomic applications coming soon. RNAscope is the gold standard for RNA ISH -pr...
    Speaker: Blake McAlpin, PhD , Paul Liu, Ph.D.
    Sponsored By: Leica Biosystems
    12
    MAR 27, 2024 | 9:00 AM
    PART 1: Utilizing the 6-base genome to investigate the dynamics of enhancer DNA methylation during cellular differentiation
    PART 1: Utilizing the 6-base genome to investigate the dynamics...
    Join Dr. Emily Hodges, assistant professor of biochemistry at Vanderbilt University, to learn more about how the Hodges Lab is utilizing the 6-base genome to investigate the dynamics of enha...
    Speaker: Dr. Emily Hodges
    Sponsored By: biomodal
    11
    MAR 26, 2024 | 9:00 AM
    Expanding Proteomic Horizons with Single-Molecule Proteome and Proteoform Analysis
    Expanding Proteomic Horizons with Single-Molecule Proteome and...
    The field of proteomics is undergoing a revolution to better quantify proteins and unlock the dynamic and valuable source of functional biological insight held in the proteome. Single-molecu...
    Speaker: Parag Mallick, Ph.D. , Andreas Hühmer, Ph.D.
    Sponsored By: Nautilus Biotechnology
    9
     
     
  • MAR 20, 2024 | 8:00 AM
    Introducing the first dual reporter application for Luminex xMAP INTELLIFLEX DR-SE Instruments:  measurement of phosphorylated and total proteins on the same bead
    Introducing the first dual reporter application for Luminex xMAP...
    Luminex and Thermo Fisher Scientific are excited to feature two presentations highlighting the advanced features of the Invitrogen™ Luminex® xMAP® INTELLIFLEX™ DR-SE inst...
    Speaker: Sherry Dunbar, Ph.D., MBA , Sigrun Badrnya, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    11
    On Demand
    C.E. CREDITS
    Visualizing Protein Aggregates at the Single-Molecule Level
    Visualizing Protein Aggregates at the Single-Molecule Level
    Protein misfolding and aggregation are key features observed in numerous neurodegenerative conditions, such as Alzheimer's and Parkinson's disease. The oligomers formed during the ag...
    Speaker: Mathew H. Horrocks, PhD
    Presented at: Neuroscience Virtual Event Series 2024
    3
    On Demand
    C.E. CREDITS
    Picodroplets Enabling High Throughput Single Cell Screening and Isolation
    Picodroplets Enabling High Throughput Single Cell Screening and...
    The study of a single cell, the fundamental unit of our complex bodies, has become an important field in cellular biology, and researchers are using single-cell analysis to shed new light on...
    Speaker: Romina Durigon, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2024
    4
    NOV 01, 2023 | 7:30 AM
    Keynote Presentation: Microfluidics and CRISPR-Diagnostics/Therapy with Live Q&A
    Keynote Presentation: Microfluidics and CRISPR-Diagnostics/Therapy...
    Coronavirus Disease 2019 (COVID-19) has driven the use of nucleic acid testing technology in clinical testing. There is a growing need for point-of-care testing (POCT)......
    Speaker: Xingyu Jiang, PhD
    Presented at: CRISPR Virtual Event Series 2023
    1
    On Demand
    Multifaceted Community Analyses Uncover Novel Bacterial Species in the Colorectal Tumor Niche
    Multifaceted Community Analyses Uncover Novel Bacterial Species...
    The tumor-associated microbiota is an inherent component of the tumor microenvironment across various human cancer types1. Although members of tumor-associated microbiomes can be identified...
    Speaker: Martha Zepeda Rivera, PhD
    Presented at: Cancer Research & Immuno-Oncology Week Virtual Event Series 2023
    3
     
     
  • SEP 12, 2023 | 8:00 AM
    Cell-based SPR Microscopy application in drug discovery
    Cell-based SPR Microscopy application in drug discovery
    SPRm (Surface Plasmon Resonance Microscopy) is a novel technology that enables label-free and real-time measurements of the binding affinity and kinetics of small molecules to G protein-coup...
    Speaker: Dr. Shijie Wu , Dr. Marie-Laure Rives
    Sponsored By: Biosensing Instrument
    12
    On-Demand
    Multifaceted Community Analyses Uncover Novel Bacterial Species in the Colorectal Tumor Niche
    Multifaceted Community Analyses Uncover Novel Bacterial Species...
    The tumor-associated microbiota is an inherent component of the tumor microenvironment across various human cancer types1. Although members of tumor-associated microbiomes can be identified t...
    Speaker: Martha Zepeda Rivera, PhD
    Presented at: Microbiology Week Virtual Event Series 2023
    2
    JUN 15, 2023 | 9:00 AM
    Empowering next-generation therapy development with electrophoresis technology and streamlined data integration
    Empowering next-generation therapy development with electrophoresis...
    Advancements in protein and gene therapy research have led to more complex modalities being developed. In addition, the desire for a deeper understanding of these molecules enhances the need...
    Speaker: Philip Hoang
    Sponsored By: SCIEX
    12
    MAY 16, 2023 | 8:00 AM
    Multivalent RNA CAR-T cell for malignant glioma
    Multivalent RNA CAR-T cell for malignant glioma
    The therapeutic use of chimeric antigen receptor T cells has achieved significant success in the treatment of B cells malignancies. Despite promising results in mouse tumor models, a similar...
    Speaker: Prof. Denis Migliorini
    Sponsored By: MaxCyte®
    13
    MAY 16, 2023 | 5:30 AM
    Sequencing Single-Strand Mismatch and Damage Patterns by Long-Read Sequencing
    Sequencing Single-Strand Mismatch and Damage Patterns by Long-Read...
    Mutations accumulate in the genome of every cell of the body throughout life, causing cancer and other genetic diseases....
    Speaker: Gilad Evrony, MD, PhD
    Presented at: Genetics Week Virtual Event Series 2023
    2
     
     
  • MAR 16, 2023 | 8:00 AM
    Studying protein polymerization with mass photometry
    Studying protein polymerization with mass photometry
    Date: March 16, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Protein polymerization underpins major biological processes, such as cell division and intracellular transport, while und...
    Speaker: Nikolas Hundt
    Sponsored By: Refeyn
    20
    FEB 22, 2023 | 10:30 AM
    Using Single B Technology to Develop Lead Antibody Molecules on GPCR Targets with Live Q&A
    Using Single B Technology to Develop Lead Antibody Molecules on...
    Immunogens with native conformation and a high-throughput IgG cloning platform are two of the most important key components for high quality lead antibody molecules discovery. DIMABIO’...
    Speaker: Donghui Ma, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2023
    Sponsored By: DIMA Biotech
    3
    FEB 22, 2023 | 5:30 AM
    Novel Bioassays in Picodroplets for Single-Cell Analysis
    Novel Bioassays in Picodroplets for Single-Cell Analysis
    Many current technologies used in drug discovery and preclinical development programmes typically involve multi-step operations, extensive hands-on time, and lengthy liquid handling processe...
    Speaker: Romina Durigon, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2023
    2
    FEB 15, 2023 | 7:00 AM
    Scattering Microscopy: Label-Free Imaging Approaches
    Scattering Microscopy: Label-Free Imaging Approaches
    Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
    Speaker: Philipp Kukura , Francesco Reina , Matthew Kose-Dunn , Phil Allen
    Sponsored By: Teledyne Photometrics
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