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    Tumor development

    Tumor development, or tumorigenesis, broadly describes the process by which normal cells gain malignant properties. Tumor development includes growth functions like cellular differentiation, proliferation, and metastasis.

    Webinars

    • NOV 17, 2016 | 8:30 AM
      Simultaneous, single-cell visualization of RNA and Protein
      Simultaneous, single-cell visualization of RNA and Protein
      DATE: November 17, 2016 TIME: 8:30am PT, 11:30am ET The complex interactions between transcription, translation, and post-translational modifications are hidden from view in typ...
      Speaker: Sara Becker-Catania, PhD
      Sponsored By: eBioscience Business Unit, Thermo Fisher Scientific, eBioscience Business Unit, Thermo Fisher Scientific
      4
      NOV 16, 2016 | 8:00 AM
      The important role of lncRNAs in breast cancer
      The important role of lncRNAs in breast cancer
      DATE:  November 16, 2016 TIME:  8:00am PT, 11:00am ET  Breast cancer is the most commonly diagnosed cancer in women and is the second leading cause of cancer death among wo...
      Speaker: Rebecca DeVaux, PhD , Alfredo Hidalgo-Miranda, PhD
      Sponsored By: Affymetrix, Affymetrix
      8
      NOV 08, 2016 | 6:00 AM
      New Approaches to Antibody Validation Using Immunoprecipitation and Mass Spectrometry
      New Approaches to Antibody Validation Using Immunoprecipitation...
      Antibodies are used in a broad range of research and diagnostic applications for the enrichment, detection, and quantitation of proteins and their modifications.  Hundreds of thousands o...
      Speaker: John Rogers, PhD
      Presented at: Protein and Cell Analysis Education Series
      Sponsored By: Thermo Fisher Scientific
      9 2
      NOV 04, 2016 | 10:00 AM
      Applying a multi-omics approach to tumor biomarker discovery - case studies
      Applying a multi-omics approach to tumor biomarker discovery -...
      DATE:  November 4, 2016 TIME:  10:00am PT, 1:00pm ET How do you develop clinically relevant biomarkers? Systematic tumor profiling with multi-omics tools and rapid analytical...
      Speaker: Antonia Sepulveda, MD, PhD , Yang Yang, PhD , Tamara Lotan, MD
      Sponsored By: Affymetrix, Affymetrix
      10 1
      NOV 03, 2016 | 1:30 PM
      Development of a novel method to measure circulating 1,25-Dihydroxyvitamin D in Human Serum and plasma
      Development of a novel method to measure circulating 1,25-Dihydroxyvitamin...
      We describe a novel method to measure 1,25(OH)2D. Briefly, this method was built on four pillars:  (1) the nuclear vitamin D receptor (VDR)`s ligand binding domain (LBD) as a capture mol...
      Speaker: Fabrizio Bonelli, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      3
      NOV 03, 2016 | 12:00 PM
      Use of QIAGEN® Clinical Insight (QCI™) Interpret to Elucidate Precision in Breast Cancer Targeted Therapy
      Use of QIAGEN® Clinical Insight (QCI™) Interpret to Elucidate...
      Breast cancer is a complex heterogeneous disease, with each subtype characterized by distinct clinical features and molecular alterations. The heterogeneity of breast cancer has presented mas...
      Speaker: Julie Deschenes, MBA, PhD , Dilhan Weeraratne, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      2
      NOV 03, 2016 | 7:30 AM
      Fusion genes:  what , why and how
      Fusion genes: what , why and how
      Fusion genes are hybrid genes formed by the fusion of two separate genes. Translocation, interstitial deletion and chromosomal inversions are some of the genetic events that can lead to the f...
      Speaker: Raed Samara, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      2
      NOV 01, 2016 | 8:00 AM
      Development of selection strategies for Homologous Recombination Deficient (HRD) patients utilizing a Liquid Biopsy
      Development of selection strategies for Homologous Recombination...
      DATE: November 1, 2016 TIME: 8:00AM PT, 11:00AM ET Metastatic cancer is an evolving, heterogeneous disease that becomes more complex over time through the selection of sub-clonal tumor po...
      Speaker: Mark Landers
      Sponsored By: Epic Sciences, Epic Sciences , Epic Sciences
      4
      OCT 18, 2016 | 1:00 PM
      Human Neural Organoids: "NexGen" Predictive and Personalized Regenerative Medicine Models of Brain Diseases
      Human Neural Organoids: "NexGen" Predictive and Personalized Regenerative...
      Induced pluripotent stem cells derived from patient cells have emerged as complementary tools to study human neurological disorders.  Neurxstem Inc has generated human iPSC-derived synth...
      Speaker: Rene Anand, PhD
      Presented at: SyncD³ - Where drug discovery & development meet
      0
      OCT 11, 2016 | 7:00 AM
      Two Dimensional Liquid Chromatography Applied to the Characterization of Monoclonal Antibodies and Antibody-Drug Conjugates
      Two Dimensional Liquid Chromatography Applied to the Characterization...
      DATE:  October 11, 2016 TIME:  7:00am PT, 10:00am ET Monoclonal antibodies (mAbs) have emerged as important therapeutics for the treatment of life-threatening diseases. The succ...
      Speaker: Koen Sandra, PhD
      Sponsored By: Agilent Genomics, Agilent Genomics
      5
      OCT 06, 2016 | 10:30 AM
      Precision Genomics and Precision Medicine for Immuno-Oncology
      Precision Genomics and Precision Medicine for Immuno-Oncology
      Tumors often evade immune destruction by adapting and circumventing immune checkpoints to create resistance.  This adaptive immunity can be reversed to stimulate the endogenous immune re...
      Speaker: Erin Newburn, MS, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      0
      OCT 06, 2016 | 10:30 AM
      Decoding human tumors and healthy tissue with mass cytometry
      Decoding human tumors and healthy tissue with mass cytometry
      New generations of treatments successfully target cancer cell signaling and modulate anti-cancer immunity to improve outcomes for advanced-stage malignancies. Such clinical responses are gove...
      Speaker: Jonathan Irish, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      0
      OCT 06, 2016 | 9:00 AM
      Keynote Speaker - PD-1 cancer immunotherapy
      Keynote Speaker - PD-1 cancer immunotherapy
      The immune system is capable of recognizing tumors and eliminates many early malignant cells. However, tumors evolve to evade immune attack, and the tumor microenvironment is immunosuppressiv...
      Speaker: Gordon Freeman, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      2
      OCT 06, 2016 | 7:30 AM
      Keynote Speaker: Reference Component Analysis of Single Cell Transcriptomes Reveals Cellular Heterogeneity in Colorectal Cancer
      Keynote Speaker: Reference Component Analysis of Single Cell Transcriptomes...
      Intra-tumor heterogeneity is a major obstacle to cancer treatment. Existing single-cell studies of intra-tumor heterogeneity have largely focused on DNA mutations; functional heterogeneity is...
      Speaker: Shyam Prabhakar, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      2
      OCT 05, 2016 | 12:00 PM
      Label-free FTIR imaging to distinguish malignant from non-malignant tissues
      Label-free FTIR imaging to distinguish malignant from non-malignant...
      FTIR spectroscopic imaging is an emerging tool for label-free, non-destructive characterization of tissues. The pathological annotation of tissue can be performed in an automated and objectiv...
      Speaker: Klaus Gerwert, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      1
      OCT 05, 2016 | 10:30 AM
      Comparative genetic and transcriptome analyses of Hepatocellular Carcinoma and Endometrioid Endometrial Carcinoma highlight common molecular and biological processes
      Comparative genetic and transcriptome analyses of Hepatocellular...
      Hepatocellular Carcinoma (HCC) and Endometrioid Endometrial Carcinoma (EEC) are two lethal diseases of public health importance worldwide. Understanding the mechanisms of tumor progression in...
      Speaker: Jean-Noel Billaud, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      0
      OCT 05, 2016 | 10:30 AM
      Unraveling the Complexities of Immuno-Oncology with 3D Biology™ Technology
      Unraveling the Complexities of Immuno-Oncology with 3D Biology™...
      The ability to measure changes to DNA, RNA, and protein across cell types is crucial to understanding the immune response to the environment or therapeutic treatment. NanoString Technologies...
      Speaker: Joseph Beechem, PhD , Alessandra Cesano, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      2
      OCT 05, 2016 | 7:30 AM
      Keynote Speaker: How to meet the challenge of counting and analyzing tumor cells circulating in the peripheral blood
      Keynote Speaker: How to meet the challenge of counting and analyzing...
      The talk will first report on a new patented method of counting CTCs based on the metabolism of tumor cells, that favors acidification of their near environment. In order to maintain the acid...
      Speaker: Giacinto Scoles, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      3
      SEP 28, 2016 | 9:00 AM
      Signatures of protective NK cell responses
      Signatures of protective NK cell responses
      DATE:  September 28, 2016TIME:   9:00am Pacific time, 12:00pm Eastern timeNK cells play critical roles in immune defense and reproduction but remain the most poorly under...
      Speaker: Catherine Blish, MD, PhD , Michelle Poulin, PhD
      Sponsored By: Standard BioTools, Standard BioTools
      9 1
      SEP 07, 2016 | 10:30 AM
      Diagnostic Development and Laboratory Response to Infectious Disease Outbreaks
      Diagnostic Development and Laboratory Response to Infectious Disease...
      The field of infectious disease diagnostics is ever changing with both newly identified infections such as SARS, Ebola, and Zika virus as well as yearly epidemics and potential for pandemic w...
      Speaker: Paula Revell, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2016
      3
      AUG 30, 2016 | 8:00 AM
      Challenge toward Clinical Trial for Spinal Cord Injury using iPS Cell
      Challenge toward Clinical Trial for Spinal Cord Injury using iPS...
      In our previous preclinical studies, when neural stem progenitor cells (NS/PCs)-derived from hiPSCs were transplanted into mouse or non-human primate spinal cord injury (SCI) models, long-ter...
      Speaker: Hideyuki Okano, MD, PhD
      Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
      1
      JUL 20, 2016 | 8:00 AM
      Using multiplexed IHC to effectively navigate the hidden clues of the immunological microenvironment
      Using multiplexed IHC to effectively navigate the hidden clues...
      DATE: July 20thTIME: 8AM PT, 11AM ET, 5PM CESTTherapies like ipilimumab and nivolumab  have shown the potential for approaches that direct the patient’s own immune system aga...
      Speaker: Edward Stack, PhD
      Sponsored By: Revvity
      47 1
      JUN 30, 2016 | 8:00 AM
      Surveying expression of immune checkpoint markers in the tissue microenvironment
      Surveying expression of immune checkpoint markers in the tissue...
      DATE:  June 30, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time Focusing solely on malignant cancer cells and the genes that they express is modestly just a glimpse of the...
      Speaker: Jeffrey Kim, PhD
      Sponsored By: Advanced Cell Diagnostics, Advanced Cell Diagnostics
      3 1
      JUN 15, 2016 | 8:00 AM
      Novel  PET radiochemistries: Improving understanding and detection of disease
      Novel PET radiochemistries: Improving understanding and detection...
      DATE: June 15, 2016TIME:  08:00AM PDT, 11:00AM EDT, 3:00PM GMT Positron Emission Tomography (PET) is a 3-dimensional, quantitative imaging technology that has robust clinical trans...
      Speaker: Timothy DeGrado, PhD , Roger Schibli, PhD
      Sponsored By: Revvity
      32 1
    NOV 17, 2016 | 8:30 AM
    Simultaneous, single-cell visualization of RNA and Protein
    Simultaneous, single-cell visualization of RNA and Protein
    DATE: November 17, 2016 TIME: 8:30am PT, 11:30am ET The complex interactions between transcription, translation, and post-translational modifications are hidden from view in typ...
    Speaker: Sara Becker-Catania, PhD
    Sponsored By: eBioscience Business Unit, Thermo Fisher Scientific, eBioscience Business Unit, Thermo Fisher Scientific
    4
    NOV 16, 2016 | 8:00 AM
    The important role of lncRNAs in breast cancer
    The important role of lncRNAs in breast cancer
    DATE:  November 16, 2016 TIME:  8:00am PT, 11:00am ET  Breast cancer is the most commonly diagnosed cancer in women and is the second leading cause of cancer death among wo...
    Speaker: Rebecca DeVaux, PhD , Alfredo Hidalgo-Miranda, PhD
    Sponsored By: Affymetrix, Affymetrix
    8
    NOV 08, 2016 | 6:00 AM
    New Approaches to Antibody Validation Using Immunoprecipitation and Mass Spectrometry
    New Approaches to Antibody Validation Using Immunoprecipitation...
    Antibodies are used in a broad range of research and diagnostic applications for the enrichment, detection, and quantitation of proteins and their modifications.  Hundreds of thousands o...
    Speaker: John Rogers, PhD
    Presented at: Protein and Cell Analysis Education Series
    Sponsored By: Thermo Fisher Scientific
    9 2
    NOV 04, 2016 | 10:00 AM
    Applying a multi-omics approach to tumor biomarker discovery - case studies
    Applying a multi-omics approach to tumor biomarker discovery -...
    DATE:  November 4, 2016 TIME:  10:00am PT, 1:00pm ET How do you develop clinically relevant biomarkers? Systematic tumor profiling with multi-omics tools and rapid analytical...
    Speaker: Antonia Sepulveda, MD, PhD , Yang Yang, PhD , Tamara Lotan, MD
    Sponsored By: Affymetrix, Affymetrix
    10 1
    NOV 03, 2016 | 1:30 PM
    Development of a novel method to measure circulating 1,25-Dihydroxyvitamin D in Human Serum and plasma
    Development of a novel method to measure circulating 1,25-Dihydroxyvitamin...
    We describe a novel method to measure 1,25(OH)2D. Briefly, this method was built on four pillars:  (1) the nuclear vitamin D receptor (VDR)`s ligand binding domain (LBD) as a capture mol...
    Speaker: Fabrizio Bonelli, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    3
     
     
  • NOV 03, 2016 | 12:00 PM
    Use of QIAGEN® Clinical Insight (QCI™) Interpret to Elucidate Precision in Breast Cancer Targeted Therapy
    Use of QIAGEN® Clinical Insight (QCI™) Interpret to Elucidate...
    Breast cancer is a complex heterogeneous disease, with each subtype characterized by distinct clinical features and molecular alterations. The heterogeneity of breast cancer has presented mas...
    Speaker: Julie Deschenes, MBA, PhD , Dilhan Weeraratne, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    2
    NOV 03, 2016 | 7:30 AM
    Fusion genes:  what , why and how
    Fusion genes: what , why and how
    Fusion genes are hybrid genes formed by the fusion of two separate genes. Translocation, interstitial deletion and chromosomal inversions are some of the genetic events that can lead to the f...
    Speaker: Raed Samara, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    2
    NOV 01, 2016 | 8:00 AM
    Development of selection strategies for Homologous Recombination Deficient (HRD) patients utilizing a Liquid Biopsy
    Development of selection strategies for Homologous Recombination...
    DATE: November 1, 2016 TIME: 8:00AM PT, 11:00AM ET Metastatic cancer is an evolving, heterogeneous disease that becomes more complex over time through the selection of sub-clonal tumor po...
    Speaker: Mark Landers
    Sponsored By: Epic Sciences, Epic Sciences , Epic Sciences
    4
    OCT 18, 2016 | 1:00 PM
    Human Neural Organoids: "NexGen" Predictive and Personalized Regenerative Medicine Models of Brain Diseases
    Human Neural Organoids: "NexGen" Predictive and Personalized Regenerative...
    Induced pluripotent stem cells derived from patient cells have emerged as complementary tools to study human neurological disorders.  Neurxstem Inc has generated human iPSC-derived synth...
    Speaker: Rene Anand, PhD
    Presented at: SyncD³ - Where drug discovery & development meet
    0
    OCT 11, 2016 | 7:00 AM
    Two Dimensional Liquid Chromatography Applied to the Characterization of Monoclonal Antibodies and Antibody-Drug Conjugates
    Two Dimensional Liquid Chromatography Applied to the Characterization...
    DATE:  October 11, 2016 TIME:  7:00am PT, 10:00am ET Monoclonal antibodies (mAbs) have emerged as important therapeutics for the treatment of life-threatening diseases. The succ...
    Speaker: Koen Sandra, PhD
    Sponsored By: Agilent Genomics, Agilent Genomics
    5
     
     
  • OCT 06, 2016 | 10:30 AM
    Precision Genomics and Precision Medicine for Immuno-Oncology
    Precision Genomics and Precision Medicine for Immuno-Oncology
    Tumors often evade immune destruction by adapting and circumventing immune checkpoints to create resistance.  This adaptive immunity can be reversed to stimulate the endogenous immune re...
    Speaker: Erin Newburn, MS, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    0
    OCT 06, 2016 | 10:30 AM
    Decoding human tumors and healthy tissue with mass cytometry
    Decoding human tumors and healthy tissue with mass cytometry
    New generations of treatments successfully target cancer cell signaling and modulate anti-cancer immunity to improve outcomes for advanced-stage malignancies. Such clinical responses are gove...
    Speaker: Jonathan Irish, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    0
    OCT 06, 2016 | 9:00 AM
    Keynote Speaker - PD-1 cancer immunotherapy
    Keynote Speaker - PD-1 cancer immunotherapy
    The immune system is capable of recognizing tumors and eliminates many early malignant cells. However, tumors evolve to evade immune attack, and the tumor microenvironment is immunosuppressiv...
    Speaker: Gordon Freeman, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    2
    OCT 06, 2016 | 7:30 AM
    Keynote Speaker: Reference Component Analysis of Single Cell Transcriptomes Reveals Cellular Heterogeneity in Colorectal Cancer
    Keynote Speaker: Reference Component Analysis of Single Cell Transcriptomes...
    Intra-tumor heterogeneity is a major obstacle to cancer treatment. Existing single-cell studies of intra-tumor heterogeneity have largely focused on DNA mutations; functional heterogeneity is...
    Speaker: Shyam Prabhakar, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    2
    OCT 05, 2016 | 12:00 PM
    Label-free FTIR imaging to distinguish malignant from non-malignant tissues
    Label-free FTIR imaging to distinguish malignant from non-malignant...
    FTIR spectroscopic imaging is an emerging tool for label-free, non-destructive characterization of tissues. The pathological annotation of tissue can be performed in an automated and objectiv...
    Speaker: Klaus Gerwert, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    1
     
     
  • OCT 05, 2016 | 10:30 AM
    Comparative genetic and transcriptome analyses of Hepatocellular Carcinoma and Endometrioid Endometrial Carcinoma highlight common molecular and biological processes
    Comparative genetic and transcriptome analyses of Hepatocellular...
    Hepatocellular Carcinoma (HCC) and Endometrioid Endometrial Carcinoma (EEC) are two lethal diseases of public health importance worldwide. Understanding the mechanisms of tumor progression in...
    Speaker: Jean-Noel Billaud, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    0
    OCT 05, 2016 | 10:30 AM
    Unraveling the Complexities of Immuno-Oncology with 3D Biology™ Technology
    Unraveling the Complexities of Immuno-Oncology with 3D Biology™...
    The ability to measure changes to DNA, RNA, and protein across cell types is crucial to understanding the immune response to the environment or therapeutic treatment. NanoString Technologies...
    Speaker: Joseph Beechem, PhD , Alessandra Cesano, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    2
    OCT 05, 2016 | 7:30 AM
    Keynote Speaker: How to meet the challenge of counting and analyzing tumor cells circulating in the peripheral blood
    Keynote Speaker: How to meet the challenge of counting and analyzing...
    The talk will first report on a new patented method of counting CTCs based on the metabolism of tumor cells, that favors acidification of their near environment. In order to maintain the acid...
    Speaker: Giacinto Scoles, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    3
    SEP 28, 2016 | 9:00 AM
    Signatures of protective NK cell responses
    Signatures of protective NK cell responses
    DATE:  September 28, 2016TIME:   9:00am Pacific time, 12:00pm Eastern timeNK cells play critical roles in immune defense and reproduction but remain the most poorly under...
    Speaker: Catherine Blish, MD, PhD , Michelle Poulin, PhD
    Sponsored By: Standard BioTools, Standard BioTools
    9 1
    SEP 07, 2016 | 10:30 AM
    Diagnostic Development and Laboratory Response to Infectious Disease Outbreaks
    Diagnostic Development and Laboratory Response to Infectious Disease...
    The field of infectious disease diagnostics is ever changing with both newly identified infections such as SARS, Ebola, and Zika virus as well as yearly epidemics and potential for pandemic w...
    Speaker: Paula Revell, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2016
    3
     
     
  • AUG 30, 2016 | 8:00 AM
    Challenge toward Clinical Trial for Spinal Cord Injury using iPS Cell
    Challenge toward Clinical Trial for Spinal Cord Injury using iPS...
    In our previous preclinical studies, when neural stem progenitor cells (NS/PCs)-derived from hiPSCs were transplanted into mouse or non-human primate spinal cord injury (SCI) models, long-ter...
    Speaker: Hideyuki Okano, MD, PhD
    Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
    1
    JUL 20, 2016 | 8:00 AM
    Using multiplexed IHC to effectively navigate the hidden clues of the immunological microenvironment
    Using multiplexed IHC to effectively navigate the hidden clues...
    DATE: July 20thTIME: 8AM PT, 11AM ET, 5PM CESTTherapies like ipilimumab and nivolumab  have shown the potential for approaches that direct the patient’s own immune system aga...
    Speaker: Edward Stack, PhD
    Sponsored By: Revvity
    47 1
    JUN 30, 2016 | 8:00 AM
    Surveying expression of immune checkpoint markers in the tissue microenvironment
    Surveying expression of immune checkpoint markers in the tissue...
    DATE:  June 30, 2016 TIME:  8:00am Pacific time, 11:00am Eastern time Focusing solely on malignant cancer cells and the genes that they express is modestly just a glimpse of the...
    Speaker: Jeffrey Kim, PhD
    Sponsored By: Advanced Cell Diagnostics, Advanced Cell Diagnostics
    3 1
    JUN 15, 2016 | 8:00 AM
    Novel  PET radiochemistries: Improving understanding and detection of disease
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    DATE: June 15, 2016TIME:  08:00AM PDT, 11:00AM EDT, 3:00PM GMT Positron Emission Tomography (PET) is a 3-dimensional, quantitative imaging technology that has robust clinical trans...
    Speaker: Timothy DeGrado, PhD , Roger Schibli, PhD
    Sponsored By: Revvity
    32 1
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