Viral vectors are tools commonly used by molecular biologists to deliver genetic material into cells. This process can be performed inside a living organism or in cell culture. Viruses have evolved specialized molecular mechanisms to efficiently transport their genomes inside the cells they infect.
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From Discovery to Clinic: Comprehensive CRISPR Solutions for Therapeutic Development CRISPR gene editing has revolutionized the field of molecular biology, offering precise, efficient, and v...
Mass Photometry (MP) and Macro Mass Photometry (MMP) are complementary, label-free techniques that analyze biomolecules and therapeutic vectors directly in solution with single-particle reso...
Analytical ultracentrifugation is an established method during the development of therapeutic proteins and antibodies and contributes supporting information regarding the size, oligomerizati...
Gene therapy is defined as the treatment of disease by transfer of genetic material into cells, to prevent, treat and potentially even cure a disease. Gene therapies can work by several mech...
Gene therapy holds potential for treating neurological diseases by delivering genetic information into specific cell types. However, selective and efficient targeting of cell types remains c...
Effective cellular therapies for solid tumors remain elusive. Advances in gene editing and synthetic biology offer great potential for improving the safety and functionality of engineered ce...
Adeno-associated virus (AAV) are increasingly produced as they hold tremendous potential in gene therapy. At research level, small quantities are produced for proof of concept studies. Howev...
The use of adeno-associated viruses (AAV) as gene delivery vectors has vast potential for the treatment of many severe human diseases. A small group of intensively studied AAV capsids have b...
While HSC research holds immense potential for regenerative medicine and disease treatment, the field poses significant challenges. Successful isolation and purification — and the abil...
Achieving consistent AAV quantification with the QuantStudio Absolute Q AutoRun dPCR Suite Accurate quantification of AAV vectors is crucial for quality control and timely decision-making du...
Date: April 20, 2023 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) A recent systematic review found that more than half of known infectious diseases will be aggravated by climate hazards,...
Date: April 12, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Recombinant adeno-associated viruses (AAVs), lentiviral vectors (LVV), and adenoviru...
As the use of engineered cells for the production of numerous research and clinical applications increases, the need to monitor multiple markers representing the stability and quality of the...