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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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SEP 23, 2020Cell & Molecular Biology
In order to infect a cell, the SARS-CoV-2 virus has to find a way in. It can use receptors on the surface of cells that ...Written By: Carmen LeitchSEP 17, 2020Immunology
Pharmaceutical giant Pfizer, in partnership with BioNTech has reported that one of its lead vaccine candidates has shown ...Written By: Tara FernandesSEP 14, 2020Cancer
It is often unknown whether a patient will respond to a treatment until it is in full swing. New research is attempting ...Written By: Jasper CantrellSEP 13, 2020Cancer
New research published in the journal Clinical Cancer Research is questioning how we treat kidney tumors. According ...Written By: Kathryn DeMuth SullivanSEP 12, 2020Cancer
A study from City of Hope published in the journal Carcinogenesis reports that the use of the natural botanical And ...Written By: Kathryn DeMuth SullivanSEP 11, 2020Immunology
P53 is an infamous process gene at the core of the development of tumors. When P53 functional, it pau ...Written By: Amanda MikyskaSEP 11, 2020Immunology
Canadian researchers have discovered that a drug used to treat coronavirus infections in cats shows promise in helping C ...Written By: Tara FernandesSEP 04, 2020Cancer
One of the hallmarks of evolution is the oxidative phosphorylation metabolic system. Not only does it produce energy in ...Written By: Jasper CantrellSEP 03, 2020Clinical & Molecular DX
The colon, also known as the large intestine, is where the final stages of digestion happen. Here, water, salts, and rem ...Written By: Tara FernandesAUG 31, 2020Cancer
Chemoresistance is a serious problem for many cancer therapies. Solutions to this problem are harder to come by than the ...Written By: Jasper CantrellAUG 31, 2020Microbiology
Candida auris is a fungal pathogen that was initially reported in 2009. Its origins are unclear, but it has been found i ...Written By: Carmen LeitchAUG 28, 2020Cancer
Genome repair is one of the big-ticket research areas for the future of medicine. CRISPR-Cas9 systems can edit the genom ...Written By: Jasper CantrellAUG 26, 2020Cancer
The body is an amazing and complex system of pathways, all working together in harmony. However, cancer can quickly disr ...Written By: Jasper CantrellAUG 24, 2020Cancer
Once upon a time, stem cells were the talk of the town. They really are amazing, with some capable of turning into any o ...Written By: Jasper CantrellAUG 19, 2020Cancer
Drug targets often focus on one thing, inhibiting or activating some critical function in a cell. Cancer drugs are no di ...Written By: Jasper CantrellAUG 17, 2020Cancer
One of cancer’s most aggravating qualities is its ability to control the microenvironment around it. This control ...Written By: Jasper CantrellAUG 12, 2020Cancer
Since the 1940s, chemotherapy has been a primary treatment option for cancer. The late 20th century brought a new type o ...Written By: Jasper CantrellAUG 07, 2020Cancer
Are people with Down syndrome protected from developing solid tumors in some way? So suggests new research published in ...Written By: Kathryn DeMuth SullivanAUG 06, 2020Clinical & Molecular DX
In a study published in Science Advances, scientists propose a new method for diagnosing gastric cancer, the third leadi ...Written By: Tara FernandesAUG 05, 2020Cancer
Cell-free DNA (cfDNA) are small pieces of genomic DNA that have escaped into the bloodstream either through active relea ...Written By: Jasper CantrellAUG 04, 2020Space & Astronomy
Outside of the Earth's magnetic field exist many kinds of dangerous radiation. These include ultraviolet, X-rays, an ...Written By: Annie LennonJUL 31, 2020Cancer
One of the great things about research is its creativity, which can lead to interesting experiments, odd but impactful i ...Written By: Jasper CantrellJUL 20, 2020Cancer
In the never-ending search for the next treatment or cure, many researchers turn towards nature. The study of black pepp ...Written By: Jasper CantrellJUL 20, 2020Cell & Molecular Biology
The diseases cat scratch fever and trench fever are both caused by Bartonella bacteria. Animals can transmit these patho ...Written By: Carmen Leitch
SEP 23, 2020
Cell & Molecular Biology
In order to infect a cell, the SARS-CoV-2 virus has to find a way in. It can use receptors on the surface of cells that
...
Written By:
Carmen Leitch
SEP 17, 2020
Immunology
Pharmaceutical giant Pfizer, in partnership with BioNTech has reported that one of its lead vaccine candidates has shown
...
Written By:
Tara Fernandes
SEP 14, 2020
Cancer
It is often unknown whether a patient will respond to a treatment until it is in full swing. New research is attempting
...
Written By:
Jasper Cantrell
SEP 13, 2020
Cancer
New research published in the journal Clinical Cancer Research is questioning how we treat kidney tumors. According
...
Written By:
Kathryn DeMuth Sullivan
SEP 12, 2020
Cancer
A study from City of Hope published in the journal Carcinogenesis reports that the use of the natural botanical And
...
Written By:
Kathryn DeMuth Sullivan
SEP 11, 2020
Immunology
P53 is an infamous process gene at the core of the development of tumors. When P53 functional, it pau
...
Written By:
Amanda Mikyska
SEP 11, 2020
Immunology
Canadian researchers have discovered that a drug used to treat coronavirus infections in cats shows promise in helping C
...
Written By:
Tara Fernandes
SEP 04, 2020
Cancer
One of the hallmarks of evolution is the oxidative phosphorylation metabolic system. Not only does it produce energy in
...
Written By:
Jasper Cantrell
SEP 03, 2020
Clinical & Molecular DX
The colon, also known as the large intestine, is where the final stages of digestion happen. Here, water, salts, and rem
...
Written By:
Tara Fernandes
AUG 31, 2020
Cancer
Chemoresistance is a serious problem for many cancer therapies. Solutions to this problem are harder to come by than the
...
Written By:
Jasper Cantrell
AUG 31, 2020
Microbiology
Candida auris is a fungal pathogen that was initially reported in 2009. Its origins are unclear, but it has been found i
...
Written By:
Carmen Leitch
AUG 28, 2020
Cancer
Genome repair is one of the big-ticket research areas for the future of medicine. CRISPR-Cas9 systems can edit the genom
...
Written By:
Jasper Cantrell
AUG 26, 2020
Cancer
The body is an amazing and complex system of pathways, all working together in harmony. However, cancer can quickly disr
...
Written By:
Jasper Cantrell
AUG 24, 2020
Cancer
Once upon a time, stem cells were the talk of the town. They really are amazing, with some capable of turning into any o
...
Written By:
Jasper Cantrell
AUG 19, 2020
Cancer
Drug targets often focus on one thing, inhibiting or activating some critical function in a cell. Cancer drugs are no di
...
Written By:
Jasper Cantrell
AUG 17, 2020
Cancer
One of cancer’s most aggravating qualities is its ability to control the microenvironment around it. This control
...
Written By:
Jasper Cantrell
AUG 12, 2020
Cancer
Since the 1940s, chemotherapy has been a primary treatment option for cancer. The late 20th century brought a new type o
...
Written By:
Jasper Cantrell
AUG 07, 2020
Cancer
Are people with Down syndrome protected from developing solid tumors in some way? So suggests new research published in
...
Written By:
Kathryn DeMuth Sullivan
AUG 06, 2020
Clinical & Molecular DX
In a study published in Science Advances, scientists propose a new method for diagnosing gastric cancer, the third leadi
...
Written By:
Tara Fernandes
AUG 05, 2020
Cancer
Cell-free DNA (cfDNA) are small pieces of genomic DNA that have escaped into the bloodstream either through active relea
...
Written By:
Jasper Cantrell
AUG 04, 2020
Space & Astronomy
Outside of the Earth's magnetic field exist many kinds of dangerous radiation. These include ultraviolet, X-rays, an
...
Written By:
Annie Lennon
JUL 31, 2020
Cancer
One of the great things about research is its creativity, which can lead to interesting experiments, odd but impactful i
...
Written By:
Jasper Cantrell
JUL 20, 2020
Cancer
In the never-ending search for the next treatment or cure, many researchers turn towards nature. The study of black pepp
...
Written By:
Jasper Cantrell
JUL 20, 2020
Cell & Molecular Biology
The diseases cat scratch fever and trench fever are both caused by Bartonella bacteria. Animals can transmit these patho
...
Written By:
Carmen Leitch