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    Compound screening

    Compound screening in an important step in the drug discovery pipeline. Performed in a laboratory setting, compound screening identifies compounds in small molecules that have a beneficial biological impact. Once identified, compounds are held in libraries containing information and details in a searchable formal.

    Webinars

    • MAY 18, 2017 | 8:00 AM
      WEBINAR: Create Your Own Cellular Compound-Target Engagement Assay
      WEBINAR: Create Your Own Cellular Compound-Target Engagement Assay
      DATE: May 18, 2017TIME: 8:00AM PDT, 11:00AM ETIt is well established that ligand binding can protect proteins from thermal denaturation in a cellular milieu; however, the broad applicat...
      Speaker: Dana Haley-Vicente, Ph.D.
      Sponsored By: DiscoverX
      5
      MAY 16, 2017 | 9:00 AM
      WEBINAR: Disease Models
      WEBINAR: Disease Models
      EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
      Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      5 3
      MAY 09, 2017 | 7:00 AM
      WEBINAR: Advanced assays for high-throughput assessment of ion channel inhibition and cardiac toxicity
      WEBINAR: Advanced assays for high-throughput assessment of ion...
      DATE: May 9th, 2017TIME: 7:00AM PDT, 10:00AM ET, 2:00PM GMT Early detection and elimination of new chemical entities with cardiac or hERG liability could substantially improve...
      Speaker: Beiyan Zou, PhD , Oksana Sirenko, PhD
      Sponsored By: Molecular Devices
      6
      MAY 01, 2017 | 8:00 AM
      Using iPSCs and Genome Engineering to Build Disease Models
      Using iPSCs and Genome Engineering to Build Disease Models
      Developing therapies for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficaciou...
      Speaker: David Piper, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      APR 05, 2017 | 9:00 AM
      Sense and Sensitivity:  Screening and Characterization of fragment binders against WT GPCR drug targets using highly sensitive Biacore S200
      Sense and Sensitivity: Screening and Characterization of fragment...
      G protein coupled receptors (GPCRs) are the targets of 30-40% of all approved drugs. However many approaches successfully applied to drug discovery for soluble protein targets have made a lim...
      Speaker: Paul Belcher, PhD
      Presented at: Protein Research Live
      7
      FEB 24, 2017 | 8:00 AM
      WEBINAR: Validating the Routine Use of High Resolution QTOF LC-MS/MS for the Analysis of Pesticides in Baby Food
      WEBINAR: Validating the Routine Use of High Resolution QTOF LC-MS/MS...
      DATE: February 24th, 2017TIME: 8:00AM PT, 11:00AM ETPesticide residue analysis of baby food products represents a challenge for routine control laboratories as consequence of the string...
      Speaker: Amadeo Fernández-Alba
      Sponsored By: SCIEX
      6
      FEB 08, 2017 | 1:30 PM
      Characterization of Niemann Pick Type C mutant mice using automated cage monitoring systems
      Characterization of Niemann Pick Type C mutant mice using automated...
      DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETPerlara PBC, is a public benefit company committed to discovering small molecule therapeutics for rare genetic diseases. Our approach con...
      Speaker: Sangeetha Iyer, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      1
      DEC 07, 2016 | 9:00 AM
      The Interplay of Kinase Broad Profiling and Phenotypic Screening
      The Interplay of Kinase Broad Profiling and Phenotypic Screening
      DATE: December 7, 2016 TIME: 9:00 AM PT, 12:00 PM ET Kinases play important roles in many biological signaling pathways. Kinase inhibitors are therefore potentially found as actives in ty...
      Speaker: Edgar Jacoby, Ph.D.
      Sponsored By: DiscoverX, DiscoverX
      4
      SEP 08, 2016 | 1:30 PM
      The Paradigm Shift in Clinical Microbiology
      The Paradigm Shift in Clinical Microbiology
      Multi-Drug Resistant Organisms (MDROs) are becoming a bigger and bigger concern throughout the world. Antibiotic resistance forms and spreads faster than pharmaceutical companies have been ab...
      Speaker: Steven Cagas, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2016
      3
      AUG 30, 2016 | 8:00 AM
      ‘HipSci' and the ‘Stem cell hotel': innovative platforms for collaborative phenotyping
      ‘HipSci' and the ‘Stem cell hotel': innovative platforms for collaborative...
      We work in the framework of the Human Induced Pluripotent Stem Cells Initiative (HipSci) project, funded by the Wellcome Trust and MRC. We provide a dedicated laboratory space for collaborati...
      Speaker: Davide Danovi, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      AUG 30, 2016 | 8:00 AM
      Tissue engineering with human pluripotent stem cells
      Tissue engineering with human pluripotent stem cells
      One of the ultimate goals in Regenerative Medicine is the generation of pluripotent stem cells (PSCs) directly from somatic cells obtained from patients. Although major findings in the defini...
      Speaker: Nuria Montserrat, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      MAY 25, 2016 | 8:00 AM
      Novel applications of automated electrophysiology in ion channel drug discovery
      Novel applications of automated electrophysiology in ion channel...
      DATE:  May 25, 2016 TIME:  8am Pacific time, 11am Eastern time, 4pm UK time, 5pm European time, 11pm Beijing time In this two-part webinar, we will be presenting the following t...
      Speaker: David Wei, PhD , Rok Cerne, MD, PhD
      Sponsored By: Molecular Devices, Molecular Devices
      4 1
      MAY 24, 2016 | 8:00 AM
      Implement high-throughput 3D image analysis for samples from subcellular structures to spheroids
      Implement high-throughput 3D image analysis for samples from subcellular...
      DATE:  May 24, 2016 TIME:   8am Pacific time, 11am Eastern time, 4pm BST, 5pm CEST 3D assays have been gaining popularity as researchers look for models with improved physiologi...
      Speaker: Oksana Sirenko, PhD , Steven Luke
      Sponsored By: Molecular Devices, Molecular Devices
      7 1
      DEC 02, 2015 | 8:00 AM
      WEBINAR: Novel Psychoactive Substances: challenges and choices in forensic toxicology
      WEBINAR: Novel Psychoactive Substances: challenges and choices...
      Live Webinar: December 2, 2015 8:00am PST In recent years, there has been a dramatic increase in the number of new designer drugs designed to mimic the effects of controlled substances. &n...
      Speaker: Julia Pearson, PhD, DABFT
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      8
      OCT 01, 2015 | 8:00 AM
      WEBINAR: Close your uncertainty gap with High Resolution Mass Spectrometry
      WEBINAR: Close your uncertainty gap with High Resolution Mass...
      Is your lab constantly challenged by case back log while trying to validate new methods to identify designer drugs? Your challenge is common to many forensic toxicology labs around the world....
      Speaker: Maciej Bromirski, MSc , Kristine Van Natta
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      2 1
      SEP 16, 2015 | 8:00 AM
      Diversity-Oriented Synthesis for Discovery of Novel Therapeutics
      Diversity-Oriented Synthesis for Discovery of Novel Therapeutics
      Recent evidence demonstrating the importance of structural complexity in advancing compounds to the clinic points to the need for enhancing small molecule screening collections with sp3-rich ...
      Speaker: Lisa Marcaurelle
      Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
      2
      SEP 16, 2015 | 7:00 AM
      Open Science for Rare and Neglected Diseases
      Open Science for Rare and Neglected Diseases
      As a computational scientist I have been fortunate to work with many collaborators to generate biological data to train and test my models. We are in a position with increasing amounts of dat...
      Speaker: Sean Ekins
      Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
      4
      SEP 16, 2015 | 5:00 AM
      Synthetic Chemists to Aid the Community for Open Antimicrobial Drug Discovery
      Synthetic Chemists to Aid the Community for Open Antimicrobial...
      The antibiotic pipeline is broken, with a dearth of new antibiotics, a collapse in pharmaceutical company research1, and the exhaustion of chemical diversity contained in pharma libraries. "T...
      Speaker: Mark Blaskovich
      Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
      2
      SEP 03, 2015 | 7:30 AM
      Keynote: Using New Technology to Control Healthcare Associated Disease
      Keynote: Using New Technology to Control Healthcare Associated...
      Control of infection from methicillin resistant Staphylococcus aureus (MRSA) has been a healthcare focus for more than 50 years. One of the reasons that active surveillance testing (AST) for...
      Speaker: Lance Peterson, MD, FASCP, FIDSA, FAAM, FSHEA
      Presented at: Microbiology Virtual Event Series 2015
      2
      SEP 02, 2015 | 12:00 PM
      Polyamines in bacterial growth and biofilm formation
      Polyamines in bacterial growth and biofilm formation
      Polyamines are small, mostly linear organic molecules found in almost all living cells, and are positively charged at physiological pH. As a consequence of their positive charge, polyamines b...
      Speaker: Anthony Michael, PhD
      Presented at: Microbiology Virtual Event Series 2015
      3
      MAY 26, 2015 | 6:00 AM
      Cell-Imaging and Luminescence Based Cytotoxicity Analysis using the EnSight Multimode Plate Reader
      Cell-Imaging and Luminescence Based Cytotoxicity Analysis using...
      Sign up here to watch this Webinar On DemandCytotoxicity remains one of the major causes of drug withdrawal and there is an urgent need for reliable and time-saving assay workflows. Cells exp...
      Speaker: Philip Gribbon , Frauke Haenel, PhD
      Sponsored By: Revvity
      24 1
      JAN 28, 2015 | 8:00 AM
      Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry
      Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry
      Drug developers are rapidly adopting three-dimensional (3D) cell cultures for drug screening since they provide a more physiologically relevant environment than two-dimensional cell cultures ...
      Speaker: Nicky Slawny, PhD , Mike Kowalski, Ph.D.
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      0
      NOV 12, 2014 | 8:00 AM
      Hallmarks of cancer - Detect and quantify cell death signatures with high content imaging
      Hallmarks of cancer - Detect and quantify cell death signatures...
      Dr. Oliver Kepp will be presenting on:Immunogenic cell death fingerprinting utilizing a high-throughput screening approachThe strategy of immunogenic cell death fingerprinting has been design...
      Speaker: Oliver Kepp, PhD and Jayne A. Hesley
      Sponsored By: Molecular Devices, Molecular Devices
      33
      SEP 24, 2014 | 3:00 PM
      Site-directed ligand discovery for cryptic sites and other challenging targets
      Site-directed ligand discovery for cryptic sites and other challenging...
      Protein-protein interactions and allosterically regulated enzymes have been challenging but important targets for probe- and drug discovery. We and others have found that fragment-based lead...
      Speaker: Michelle Arkin, PhD
      Presented at: Advances in Drug Discovery and Development
      20
    MAY 18, 2017 | 8:00 AM
    WEBINAR: Create Your Own Cellular Compound-Target Engagement Assay
    WEBINAR: Create Your Own Cellular Compound-Target Engagement Assay
    DATE: May 18, 2017TIME: 8:00AM PDT, 11:00AM ETIt is well established that ligand binding can protect proteins from thermal denaturation in a cellular milieu; however, the broad applicat...
    Speaker: Dana Haley-Vicente, Ph.D.
    Sponsored By: DiscoverX
    5
    MAY 16, 2017 | 9:00 AM
    WEBINAR: Disease Models
    WEBINAR: Disease Models
    EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series.  As a thought-leader in science our first commit...
    Speaker: David Piper, PhD , Mark Kennedy, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    5 3
    MAY 09, 2017 | 7:00 AM
    WEBINAR: Advanced assays for high-throughput assessment of ion channel inhibition and cardiac toxicity
    WEBINAR: Advanced assays for high-throughput assessment of ion...
    DATE: May 9th, 2017TIME: 7:00AM PDT, 10:00AM ET, 2:00PM GMT Early detection and elimination of new chemical entities with cardiac or hERG liability could substantially improve...
    Speaker: Beiyan Zou, PhD , Oksana Sirenko, PhD
    Sponsored By: Molecular Devices
    6
    MAY 01, 2017 | 8:00 AM
    Using iPSCs and Genome Engineering to Build Disease Models
    Using iPSCs and Genome Engineering to Build Disease Models
    Developing therapies for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficaciou...
    Speaker: David Piper, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    APR 05, 2017 | 9:00 AM
    Sense and Sensitivity:  Screening and Characterization of fragment binders against WT GPCR drug targets using highly sensitive Biacore S200
    Sense and Sensitivity: Screening and Characterization of fragment...
    G protein coupled receptors (GPCRs) are the targets of 30-40% of all approved drugs. However many approaches successfully applied to drug discovery for soluble protein targets have made a lim...
    Speaker: Paul Belcher, PhD
    Presented at: Protein Research Live
    7
     
     
  • FEB 24, 2017 | 8:00 AM
    WEBINAR: Validating the Routine Use of High Resolution QTOF LC-MS/MS for the Analysis of Pesticides in Baby Food
    WEBINAR: Validating the Routine Use of High Resolution QTOF LC-MS/MS...
    DATE: February 24th, 2017TIME: 8:00AM PT, 11:00AM ETPesticide residue analysis of baby food products represents a challenge for routine control laboratories as consequence of the string...
    Speaker: Amadeo Fernández-Alba
    Sponsored By: SCIEX
    6
    FEB 08, 2017 | 1:30 PM
    Characterization of Niemann Pick Type C mutant mice using automated cage monitoring systems
    Characterization of Niemann Pick Type C mutant mice using automated...
    DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETPerlara PBC, is a public benefit company committed to discovering small molecule therapeutics for rare genetic diseases. Our approach con...
    Speaker: Sangeetha Iyer, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    1
    DEC 07, 2016 | 9:00 AM
    The Interplay of Kinase Broad Profiling and Phenotypic Screening
    The Interplay of Kinase Broad Profiling and Phenotypic Screening
    DATE: December 7, 2016 TIME: 9:00 AM PT, 12:00 PM ET Kinases play important roles in many biological signaling pathways. Kinase inhibitors are therefore potentially found as actives in ty...
    Speaker: Edgar Jacoby, Ph.D.
    Sponsored By: DiscoverX, DiscoverX
    4
    SEP 08, 2016 | 1:30 PM
    The Paradigm Shift in Clinical Microbiology
    The Paradigm Shift in Clinical Microbiology
    Multi-Drug Resistant Organisms (MDROs) are becoming a bigger and bigger concern throughout the world. Antibiotic resistance forms and spreads faster than pharmaceutical companies have been ab...
    Speaker: Steven Cagas, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2016
    3
    AUG 30, 2016 | 8:00 AM
    ‘HipSci' and the ‘Stem cell hotel': innovative platforms for collaborative phenotyping
    ‘HipSci' and the ‘Stem cell hotel': innovative platforms for collaborative...
    We work in the framework of the Human Induced Pluripotent Stem Cells Initiative (HipSci) project, funded by the Wellcome Trust and MRC. We provide a dedicated laboratory space for collaborati...
    Speaker: Davide Danovi, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
     
     
  • AUG 30, 2016 | 8:00 AM
    Tissue engineering with human pluripotent stem cells
    Tissue engineering with human pluripotent stem cells
    One of the ultimate goals in Regenerative Medicine is the generation of pluripotent stem cells (PSCs) directly from somatic cells obtained from patients. Although major findings in the defini...
    Speaker: Nuria Montserrat, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    MAY 25, 2016 | 8:00 AM
    Novel applications of automated electrophysiology in ion channel drug discovery
    Novel applications of automated electrophysiology in ion channel...
    DATE:  May 25, 2016 TIME:  8am Pacific time, 11am Eastern time, 4pm UK time, 5pm European time, 11pm Beijing time In this two-part webinar, we will be presenting the following t...
    Speaker: David Wei, PhD , Rok Cerne, MD, PhD
    Sponsored By: Molecular Devices, Molecular Devices
    4 1
    MAY 24, 2016 | 8:00 AM
    Implement high-throughput 3D image analysis for samples from subcellular structures to spheroids
    Implement high-throughput 3D image analysis for samples from subcellular...
    DATE:  May 24, 2016 TIME:   8am Pacific time, 11am Eastern time, 4pm BST, 5pm CEST 3D assays have been gaining popularity as researchers look for models with improved physiologi...
    Speaker: Oksana Sirenko, PhD , Steven Luke
    Sponsored By: Molecular Devices, Molecular Devices
    7 1
    DEC 02, 2015 | 8:00 AM
    WEBINAR: Novel Psychoactive Substances: challenges and choices in forensic toxicology
    WEBINAR: Novel Psychoactive Substances: challenges and choices...
    Live Webinar: December 2, 2015 8:00am PST In recent years, there has been a dramatic increase in the number of new designer drugs designed to mimic the effects of controlled substances. &n...
    Speaker: Julia Pearson, PhD, DABFT
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    8
    OCT 01, 2015 | 8:00 AM
    WEBINAR: Close your uncertainty gap with High Resolution Mass Spectrometry
    WEBINAR: Close your uncertainty gap with High Resolution Mass...
    Is your lab constantly challenged by case back log while trying to validate new methods to identify designer drugs? Your challenge is common to many forensic toxicology labs around the world....
    Speaker: Maciej Bromirski, MSc , Kristine Van Natta
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    2 1
     
     
  • SEP 16, 2015 | 8:00 AM
    Diversity-Oriented Synthesis for Discovery of Novel Therapeutics
    Diversity-Oriented Synthesis for Discovery of Novel Therapeutics
    Recent evidence demonstrating the importance of structural complexity in advancing compounds to the clinic points to the need for enhancing small molecule screening collections with sp3-rich ...
    Speaker: Lisa Marcaurelle
    Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
    2
    SEP 16, 2015 | 7:00 AM
    Open Science for Rare and Neglected Diseases
    Open Science for Rare and Neglected Diseases
    As a computational scientist I have been fortunate to work with many collaborators to generate biological data to train and test my models. We are in a position with increasing amounts of dat...
    Speaker: Sean Ekins
    Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
    4
    SEP 16, 2015 | 5:00 AM
    Synthetic Chemists to Aid the Community for Open Antimicrobial Drug Discovery
    Synthetic Chemists to Aid the Community for Open Antimicrobial...
    The antibiotic pipeline is broken, with a dearth of new antibiotics, a collapse in pharmaceutical company research1, and the exhaustion of chemical diversity contained in pharma libraries. "T...
    Speaker: Mark Blaskovich
    Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
    2
    SEP 03, 2015 | 7:30 AM
    Keynote: Using New Technology to Control Healthcare Associated Disease
    Keynote: Using New Technology to Control Healthcare Associated...
    Control of infection from methicillin resistant Staphylococcus aureus (MRSA) has been a healthcare focus for more than 50 years. One of the reasons that active surveillance testing (AST) for...
    Speaker: Lance Peterson, MD, FASCP, FIDSA, FAAM, FSHEA
    Presented at: Microbiology Virtual Event Series 2015
    2
    SEP 02, 2015 | 12:00 PM
    Polyamines in bacterial growth and biofilm formation
    Polyamines in bacterial growth and biofilm formation
    Polyamines are small, mostly linear organic molecules found in almost all living cells, and are positively charged at physiological pH. As a consequence of their positive charge, polyamines b...
    Speaker: Anthony Michael, PhD
    Presented at: Microbiology Virtual Event Series 2015
    3
     
     
  • MAY 26, 2015 | 6:00 AM
    Cell-Imaging and Luminescence Based Cytotoxicity Analysis using the EnSight Multimode Plate Reader
    Cell-Imaging and Luminescence Based Cytotoxicity Analysis using...
    Sign up here to watch this Webinar On DemandCytotoxicity remains one of the major causes of drug withdrawal and there is an urgent need for reliable and time-saving assay workflows. Cells exp...
    Speaker: Philip Gribbon , Frauke Haenel, PhD
    Sponsored By: Revvity
    24 1
    JAN 28, 2015 | 8:00 AM
    Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry
    Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry
    Drug developers are rapidly adopting three-dimensional (3D) cell cultures for drug screening since they provide a more physiologically relevant environment than two-dimensional cell cultures ...
    Speaker: Nicky Slawny, PhD , Mike Kowalski, Ph.D.
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    0
    NOV 12, 2014 | 8:00 AM
    Hallmarks of cancer - Detect and quantify cell death signatures with high content imaging
    Hallmarks of cancer - Detect and quantify cell death signatures...
    Dr. Oliver Kepp will be presenting on:Immunogenic cell death fingerprinting utilizing a high-throughput screening approachThe strategy of immunogenic cell death fingerprinting has been design...
    Speaker: Oliver Kepp, PhD and Jayne A. Hesley
    Sponsored By: Molecular Devices, Molecular Devices
    33
    SEP 24, 2014 | 3:00 PM
    Site-directed ligand discovery for cryptic sites and other challenging targets
    Site-directed ligand discovery for cryptic sites and other challenging...
    Protein-protein interactions and allosterically regulated enzymes have been challenging but important targets for probe- and drug discovery. We and others have found that fragment-based lead...
    Speaker: Michelle Arkin, PhD
    Presented at: Advances in Drug Discovery and Development
    20
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