Discovery informatics encompasses a variety of technological and mathematical fields such as statistics, data programming, and machine learning. Using an interdisciplinary approach, Discovery informatics aims to generate novel ideas and technologies by integrating, analyzing, and understanding large and complex data sets.
When the human genome was sequenced almost 15 years ago, it was a milestone for the understanding of an individual’s genome. However to fully understand a disease, millions of ind...
AstraZeneca has an ambition to create a porous organisation, seamlessly collaborating with external partners. This desire has led to the establishment of the AstraZeneca-MRC UK Centre for Lea...
Complex disease phenotypes - obesity, type II diabetes, and cancer challenge simple models in both evolution and biology. Examination of molecular networks and their dynamic behavior o...
In today’s modern laboratory, resources are often stretched as laboratories struggle to manage multiple priorities, meet regulatory requirements, and contain costs. This is especially t...
Preclinical translational imaging, and specifically molecular imaging methods such as positron emission tomography (PET) or single photon emission computed tomography (SPECT) as well as magne...
Compassion fatigue, or the state of chronic stress for those caring for people or animals in distress, can affect anyone working in the lab animal sciences. This can even affect employe...
The translation gap in biomedical research can be attributed in part to differences in how outcomes are assessed in preclinical research and in the clinic. Reasons for these mismatches includ...
Analgesics are commonly employed drugs for perioperative procedures and are required for painful procedures. They include not only non-steroidal anti-inflammatory drugs (NSAIDs) but also opio...
Assessment of how changes in husbandry affect an animal can be challenging as most common methods of assessment, such as corticosterone levels, are more reliable for assessment of acute stres...
Digital technology is improving the speed and accuracy of all the world’s work processes and activities, the including the research vivarium. This presentation will address some...
Nonterminal blood collection from mice is frequently performed in biomedical research. Multiple phlebotomy sites and restraint techniques are available to investigators. Methods that minimize...
The aerodigestive tract is a combination of the respiratory tract and the upper portion of the digestive tract. As these two organ systems share many of the necessary structures used for swal...
Introduction:The cannulation of the cisterna magna in the rat is a valuable model for in-vivo sampling of cerebrospinal fluid for studying delivery of new drugs into the central nervous sys...
Compassion Fatigue can affect all those that care for and work with laboratory animals, including husbandry staff, veterinary staff, researchers, and other support staff. It is known as the &...
The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test (...
This session will explore the interpretation of multi-species scattergrams in normal and pathologic conditions. Numerous case studies will be reviewed....
Tuberculosis (TB) is the No.1 cause of death due to a single infectious agent in the world today. According to the global report from World Health Organization, one third of world population...
Conspecific aggression is a common problem amongst laboratory housed male mice. While C57BL/6 are not the most aggressive strain we house, they are exceedingly common, and dealing with...
There is a considerable interest and need for evidence-based recommendations regarding the social housing of laboratory rabbits. This presentation will review the principles surrounding the s...
Welfare First, a programme developed to recognise the importance of welfare within the life sciences sector and to meet the aims of its position statement. Animal welfare is a priority,...
The study of inherited genomic variation through genome wide association studies (GWAS) promised to provide key biologic insight into common diseases of public health significance such as obe...
DATE: April 25, 2017TIME: 10:00am PT, 1:00pm ETImmunotherapy has emerged as one of the most promising options for the future treatment of a growing number of cancers and is to...
The starting point for an interaction between a patient and a clinician is almost always a set of clinical facts (aka a phenotype). Phenotype-first medicine is the standard way in which the p...
DATE: February 9, 2017TIME: 3:00pm PT, 6:00pm ETThe presentation will very briefly cover the regulatory system for lab animals in China, as well as the regulations and guidelines a...
When the human genome was sequenced almost 15 years ago, it was a milestone for the understanding of an individual’s genome. However to fully understand a disease, millions of ind...
AstraZeneca has an ambition to create a porous organisation, seamlessly collaborating with external partners. This desire has led to the establishment of the AstraZeneca-MRC UK Centre for Lea...
Complex disease phenotypes - obesity, type II diabetes, and cancer challenge simple models in both evolution and biology. Examination of molecular networks and their dynamic behavior o...
In today’s modern laboratory, resources are often stretched as laboratories struggle to manage multiple priorities, meet regulatory requirements, and contain costs. This is especially t...
Preclinical translational imaging, and specifically molecular imaging methods such as positron emission tomography (PET) or single photon emission computed tomography (SPECT) as well as magne...
Compassion fatigue, or the state of chronic stress for those caring for people or animals in distress, can affect anyone working in the lab animal sciences. This can even affect employe...
The translation gap in biomedical research can be attributed in part to differences in how outcomes are assessed in preclinical research and in the clinic. Reasons for these mismatches includ...
Analgesics are commonly employed drugs for perioperative procedures and are required for painful procedures. They include not only non-steroidal anti-inflammatory drugs (NSAIDs) but also opio...
Assessment of how changes in husbandry affect an animal can be challenging as most common methods of assessment, such as corticosterone levels, are more reliable for assessment of acute stres...
Digital technology is improving the speed and accuracy of all the world’s work processes and activities, the including the research vivarium. This presentation will address some...
Nonterminal blood collection from mice is frequently performed in biomedical research. Multiple phlebotomy sites and restraint techniques are available to investigators. Methods that minimize...
The aerodigestive tract is a combination of the respiratory tract and the upper portion of the digestive tract. As these two organ systems share many of the necessary structures used for swal...
Introduction:The cannulation of the cisterna magna in the rat is a valuable model for in-vivo sampling of cerebrospinal fluid for studying delivery of new drugs into the central nervous sys...
Compassion Fatigue can affect all those that care for and work with laboratory animals, including husbandry staff, veterinary staff, researchers, and other support staff. It is known as the &...
The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test (...
This session will explore the interpretation of multi-species scattergrams in normal and pathologic conditions. Numerous case studies will be reviewed....
Tuberculosis (TB) is the No.1 cause of death due to a single infectious agent in the world today. According to the global report from World Health Organization, one third of world population...
Conspecific aggression is a common problem amongst laboratory housed male mice. While C57BL/6 are not the most aggressive strain we house, they are exceedingly common, and dealing with...
There is a considerable interest and need for evidence-based recommendations regarding the social housing of laboratory rabbits. This presentation will review the principles surrounding the s...
Welfare First, a programme developed to recognise the importance of welfare within the life sciences sector and to meet the aims of its position statement. Animal welfare is a priority,...
The study of inherited genomic variation through genome wide association studies (GWAS) promised to provide key biologic insight into common diseases of public health significance such as obe...
DATE: April 25, 2017TIME: 10:00am PT, 1:00pm ETImmunotherapy has emerged as one of the most promising options for the future treatment of a growing number of cancers and is to...
The starting point for an interaction between a patient and a clinician is almost always a set of clinical facts (aka a phenotype). Phenotype-first medicine is the standard way in which the p...
DATE: February 9, 2017TIME: 3:00pm PT, 6:00pm ETThe presentation will very briefly cover the regulatory system for lab animals in China, as well as the regulations and guidelines a...
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