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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • NOV 25, 2019
      Drug Discovery & Development
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      Darobactin: Promising New Drug to Combat Antibiotic Resistance
      Every year, around 700,000 people are estimated to die from drug-resistant infections thanks to our overuse of antibioti ...
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      NOV 25, 2019
      Drug Discovery & Development
      Discovery of mechanism behind Alexander disease may lead to enhanced drug development
      Discovery of mechanism behind Alexander disease may lead to enhanced drug development
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      NOV 25, 2019
      Technology
      How artificial intelligence (AI) is improving immunotherapy
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      NOV 24, 2019
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      NOV 24, 2019
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      The Fight Against Lethal Childhood Brain Cancers
      The Fight Against Lethal Childhood Brain Cancers
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      NOV 23, 2019
      Technology
      Can artificial intelligence increase tuberculosis drug development?
      Can artificial intelligence increase tuberculosis drug development?
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      NOV 23, 2019
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      Drug Seeks To Target Treatment-Resistant Epilepsy
      Drug Seeks To Target Treatment-Resistant Epilepsy
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      NOV 22, 2019
      Health & Medicine
      Federal Government Weighs in on Marijuana and Opioid Addiction
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      NOV 19, 2019
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      NOV 19, 2019
      Drug Discovery & Development
      Experimental Cholesterol-Lowering Drug
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      NOV 19, 2019
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      Psychedelic DMT Creates Vivid Waking Dream State in Brain
      Psychedelic DMT Creates Vivid Waking Dream State in Brain
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      NOV 19, 2019
      Cannabis Sciences
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      NOV 18, 2019
      Drug Discovery & Development
      FDA Approves New Drug for Sickle Cell Disease
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      NOV 16, 2019
      Genetics & Genomics
      Understanding How Loose RNA Molecules Help Rejuvenate Skin
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      NOV 14, 2019
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      Learning More About Changes in Cancer Cell Identity
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      NOV 13, 2019
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      NOV 11, 2019
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      NOV 10, 2019
      Drug Discovery & Development
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      1
      NOV 10, 2019
      Neuroscience
      Gene Mutation Identified that Protects Agaist Dementia
      Gene Mutation Identified that Protects Agaist Dementia
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      NOV 09, 2019
      Cancer
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      NOV 08, 2019
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      Does New Chinese Alzheimer's Drug Made from Seaweed Work?
      Does New Chinese Alzheimer's Drug Made from Seaweed Work?
      It has been almost two decades since the last drug for Alzheimer’s was approved. Now, Chinese reglators have grant ...
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      1
      NOV 08, 2019
      Genetics & Genomics
      New Way to Determine What Our Genes Do
      New Way to Determine What Our Genes Do
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      NOV 06, 2019
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    NOV 25, 2019
    Drug Discovery & Development
    Darobactin: Promising New Drug to Combat Antibiotic Resistance
    Darobactin: Promising New Drug to Combat Antibiotic Resistance
    Every year, around 700,000 people are estimated to die from drug-resistant infections thanks to our overuse of antibioti ...
    Written By: Annie Lennon
    1
    NOV 25, 2019
    Drug Discovery & Development
    Discovery of mechanism behind Alexander disease may lead to enhanced drug development
    Discovery of mechanism behind Alexander disease may lead to enhanced drug development
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    Written By: Nouran Amin
    1
    NOV 25, 2019
    Technology
    How artificial intelligence (AI) is improving immunotherapy
    How artificial intelligence (AI) is improving immunotherapy
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    Written By: Nouran Amin
    1
    NOV 24, 2019
    Drug Discovery & Development
    The unlikely pain killer
    The unlikely pain killer
    Pain can be anything a sunburn, a toothache, or a leg injury to name a few. The relievers that target our pain come in m ...
    Written By: Nouran Amin
    1
    NOV 24, 2019
    Drug Discovery & Development
    The Fight Against Lethal Childhood Brain Cancers
    The Fight Against Lethal Childhood Brain Cancers
    Scientists used studies on cell and animal models to reveal insights into lethal childhood brain cancers and find promis ...
    Written By: Nouran Amin
    1
     
     
  • NOV 23, 2019
    Technology
    Can artificial intelligence increase tuberculosis drug development?
    Can artificial intelligence increase tuberculosis drug development?
    It’s no secret that there is a shortage of tuberculosis drug development. To combat this issue, researchers at the ...
    Written By: Nouran Amin
    1
    NOV 23, 2019
    Drug Discovery & Development
    Drug Seeks To Target Treatment-Resistant Epilepsy
    Drug Seeks To Target Treatment-Resistant Epilepsy
    Ever imagined a world where you cannot shower alone, drive by yourself, and even go to work in fear of having the next s ...
    Written By: Nouran Amin
    1
    NOV 22, 2019
    Health & Medicine
    Federal Government Weighs in on Marijuana and Opioid Addiction
    Federal Government Weighs in on Marijuana and Opioid Addiction
    The U.S. government is weighing in on the hot topic of whether or not medical marijuana is a successful tool in treating ...
    Written By: C Reardon
    1
    NOV 19, 2019
    Drug Discovery & Development
    Antibiotics from the Sea?
    Antibiotics from the Sea?
    Many of the clinically relevant antibiotics are sourced from natural substances, produced by bacteria. But because of th ...
    Written By: Nouran Amin
    1
    NOV 19, 2019
    Drug Discovery & Development
    Experimental Cholesterol-Lowering Drug
    Experimental Cholesterol-Lowering Drug
    A recent study shows that patients who take a maximum dose of statin drugs in addition to a twice-yearly injection of th ...
    Written By: Nouran Amin
    1
     
     
  • NOV 19, 2019
    Drug Discovery & Development
    Psychedelic DMT Creates Vivid Waking Dream State in Brain
    Psychedelic DMT Creates Vivid Waking Dream State in Brain
    In a new study, scientists at Imperial College London investigated how powerful psychedelic dimethyltryptamine (DMT) alt ...
    Written By: Annie Lennon
    1
    NOV 19, 2019
    Cannabis Sciences
    Cannabis Can't Simply Replace Opioids for Pain Management
    Cannabis Can't Simply Replace Opioids for Pain Management
    According to the research, cannabis is not effective when it comes to treating individuals struggling with opioid use di ...
    Written By: Kara Marker
    1
    NOV 18, 2019
    Drug Discovery & Development
    FDA Approves New Drug for Sickle Cell Disease
    FDA Approves New Drug for Sickle Cell Disease
    Sickle cell disease affects approximately 100,000 Americans. Currently, the only available cure for the disease is a cos ...
    Written By: Annie Lennon
    1
    NOV 16, 2019
    Genetics & Genomics
    Understanding How Loose RNA Molecules Help Rejuvenate Skin
    Understanding How Loose RNA Molecules Help Rejuvenate Skin
    This work may help develop new treatments for skin that is aging or damaged by wounds or burns.
    Written By: Carmen Leitch
    1
    NOV 14, 2019
    Genetics & Genomics
    Learning More About Changes in Cancer Cell Identity
    Learning More About Changes in Cancer Cell Identity
    Cancer cells can change their identity and can take on new functions and characteristics, which is often rooted in epige ...
    Written By: Carmen Leitch
    1
     
     
  • NOV 13, 2019
    Drug Discovery & Development
    The Side-Effects to A Common Blood Cancer Drug
    The Side-Effects to A Common Blood Cancer Drug
    In a study published in Scientific Reports, a popular cancer drug, known as ruxolitnib, was found to cause an increased ...
    Written By: Nouran Amin
    1
    NOV 11, 2019
    Neuroscience
    Suicidal Mitochondria Responsible for ALS
    Suicidal Mitochondria Responsible for ALS
    Scientists at Northwestern University have dicovered a new mechanism in the brain that may be responsable for the early ...
    Written By: Annie Lennon
    1
    NOV 11, 2019
    Neuroscience
    The Women Who Can Smell Without Olfactory Bulbs
    The Women Who Can Smell Without Olfactory Bulbs
    Until now, it has been commonly accepted that our sense of smell depends on the transmission of olfactory information fr ...
    Written By: Annie Lennon
    2
    NOV 10, 2019
    Drug Discovery & Development
    Promising Results for New Vaccine Against Dengue Fever
    Promising Results for New Vaccine Against Dengue Fever
    Dengue fever is an illness transmitted by mosquito bites. Affecting around 390 million people per year, if left untreate ...
    Written By: Annie Lennon
    1
    NOV 10, 2019
    Neuroscience
    Gene Mutation Identified that Protects Agaist Dementia
    Gene Mutation Identified that Protects Agaist Dementia
    For over two decades, researchers have been studying an extended family of over 1,200 people from Columbia known for hav ...
    Written By: Annie Lennon
    1
     
     
  • NOV 09, 2019
    Cancer
    Using machine learning to discover new cancer treatments
    Using machine learning to discover new cancer treatments
    Flashback fifty years ago and many of the modern world’s inventions and discoveries would have been undreamed of & ...
    Written By: Kathryn DeMuth Sullivan
    2 3
    NOV 08, 2019
    Neuroscience
    Does New Chinese Alzheimer's Drug Made from Seaweed Work?
    Does New Chinese Alzheimer's Drug Made from Seaweed Work?
    It has been almost two decades since the last drug for Alzheimer’s was approved. Now, Chinese reglators have grant ...
    Written By: Annie Lennon
    1
    NOV 08, 2019
    Genetics & Genomics
    New Way to Determine What Our Genes Do
    New Way to Determine What Our Genes Do
    Geneticists at the University of Virginia (UVA) School of Medicine have developed a new way to determine what our genes ...
    Written By: Annie Lennon
    3
    NOV 06, 2019
    Drug Discovery & Development
    Cone Snail Venom Became and Pain Therapeutics
    Cone Snail Venom Became and Pain Therapeutics
    Ever heard of conotoxins? They are bioactive peptides present in the venom of the predatory marine cone snails that are ...
    Written By: Nouran Amin
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