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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • NOV 06, 2019
      Drug Discovery & Development
      Possible New Drug Targets for Glioblastoma
      Possible New Drug Targets for Glioblastoma
      Scientists at Karolinska Institutet in Sweden were able to pinpoint 10 tumor-specific potential drug targets for the fat ...
      Written By: Nouran Amin
      3
      NOV 04, 2019
      Drug Discovery & Development
      Gene Variant Could Be a Therapeutic Target For Alzheimer Disease
      Gene Variant Could Be a Therapeutic Target For Alzheimer Disease
      A variation in genetics for an individual at high-risk for Alzheimer development has defied the odds for being dementia- ...
      Written By: Nouran Amin
      2
      NOV 04, 2019
      Drug Discovery & Development
      How Fluorescent Probes Can Enhance Drug Delivery
      How Fluorescent Probes Can Enhance Drug Delivery
      Researchers at Cornell University are working on improving the trial-and-error process that is implicated in finding eff ...
      Written By: Nouran Amin
      2
      NOV 03, 2019
      Cell & Molecular Biology
      Researchers Identify New Cellular Signaling Mechanisms
      Researchers Identify New Cellular Signaling Mechanisms
      Molecules and drugs move among cells and bind to receptors on the cell surface, which can initiate a cascade of reaction ...
      Written By: Carmen Leitch
      1
      NOV 01, 2019
      Health & Medicine
      FDA Cautions Against Cannabis Use During Pregnancy
      FDA Cautions Against Cannabis Use During Pregnancy
      A recent article published by NPR addresses the rapidly growing number of females using cannabis during pregnancy. Those ...
      Written By: C Reardon
      1
      NOV 01, 2019
      Chemistry & Physics
      Cancer Therapy Agents Inspired by Solar Technology
      Cancer Therapy Agents Inspired by Solar Technology
      In a recent study, a group of biomedical researchers at Michigan State University developed a new platform for tweaking ...
      Written By: Daniel Duan
      2
      OCT 31, 2019
      Cancer
      Unpacking lactate's role in the Warburg effect
      Unpacking lactate's role in the Warburg effect
      In a recent issue of Nature, the findings of one study made a particularly big splash: how and why cancer cells use ener ...
      Written By: Kathryn DeMuth Sullivan
      1
      OCT 31, 2019
      Genetics & Genomics
      Familial Alzheimer's Gene Found to Regulate Nerve Development
      Familial Alzheimer's Gene Found to Regulate Nerve Development
      An international team of scientists has now identified a process that plays a critical role in the growth of one part of ...
      Written By: Carmen Leitch
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      OCT 30, 2019
      Cancer
      How caloric restriction mimetics might prove helpful for cancer treatments
      How caloric restriction mimetics might prove helpful for cancer treatments
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      Written By: Kathryn DeMuth Sullivan
      1
      OCT 30, 2019
      Drug Discovery & Development
      Investigating a common therapeutic in ADHD treatment
      Investigating a common therapeutic in ADHD treatment
      Attention-Deficit Hyperactivity Disorder (ADHD) is a widespread condition with variable underlying causes. A common ther ...
      Written By: Nouran Amin
      1
      OCT 30, 2019
      Drug Discovery & Development
      Can Aspirin Prevent a Brain Bleed?
      Can Aspirin Prevent a Brain Bleed?
      Can aspirin prevent a brain bleed? To answer the questions, researchers rummaged through a database system looking to se ...
      Written By: Nouran Amin
      1
      OCT 30, 2019
      Drug Discovery & Development
      Advancing Nanocontainers for Drug Delivery
      Advancing Nanocontainers for Drug Delivery
      Nanocontainers work by delivering drugs to a localized region in the body, many chemotherapeutics work in that matter. T ...
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      1
      OCT 30, 2019
      Drug Discovery & Development
      Developing Animal-Free Neurotoxin Testing
      Developing Animal-Free Neurotoxin Testing
      The need to assess a group of deadly neurotoxins without turning to animal-testing may soon be a possibility. A new anim ...
      Written By: Nouran Amin
      1
      OCT 29, 2019
      Microbiology
      Antibody Discovered That May be the Key to a Universal Flu Vaccine
      Antibody Discovered That May be the Key to a Universal Flu Vaccine
      Instead of designing a new flu vaccine every year, researchers have made a breakthrough that may lead to a single vaccin ...
      Written By: Carmen Leitch
      1
      OCT 28, 2019
      Genetics & Genomics
      Super-Resolution Microscopy Reveals How DNA Damage is Repaired
      Super-Resolution Microscopy Reveals How DNA Damage is Repaired
      People that don't carry functional copies of these proteins are more likely to get diseases that arise from unstable DNA ...
      Written By: Carmen Leitch
      1
      OCT 28, 2019
      Neuroscience
      First Drug to Slow Progression of Alzheimer's Shows Promise
      First Drug to Slow Progression of Alzheimer's Shows Promise
      An estimated 5.8 million people living in the US have Alzheimer’s disease. Currently, no cure is available and any ...
      Written By: Annie Lennon
      1
      OCT 26, 2019
      Genetics & Genomics
      Gates Foundation and NIH Pledge $200 Million for Gene Therapies in Africa
      Gates Foundation and NIH Pledge $200 Million for Gene Therapies in Africa
      Over the next four years, the National Institutes of Health and the Bill and Melinda Gates Foundation plan to each inves ...
      Written By: Annie Lennon
      2
      OCT 25, 2019
      Drug Discovery & Development
      Fecal Transplants Could Treat Irritable Bowel Syndrome
      Fecal Transplants Could Treat Irritable Bowel Syndrome
      According to the American College of Gastroenterology, between 10 and 15% of Americans have Irritable Bowel Syndrome (IB ...
      Written By: Annie Lennon
      1
      OCT 25, 2019
      Drug Discovery & Development
      Novel Therapeutic For Eradicating The Flu Virus
      Novel Therapeutic For Eradicating The Flu Virus
      Public Health officials have long warned about pandemic pathogens flying fast around the world. One virus already spread ...
      Written By: Nouran Amin
      1
      OCT 24, 2019
      Drug Discovery & Development
      Converting Wood into Pharmaceutical Compounds
      Converting Wood into Pharmaceutical Compounds
      Producing toxic byproducts during the making of pharmaceuticals remains a challenge in the drug manufacturing industry. ...
      Written By: Nouran Amin
      1
      OCT 23, 2019
      Drug Discovery & Development
      Treating Gulf-War Illness with Anti-Viral Drugs
      Treating Gulf-War Illness with Anti-Viral Drugs
      Researchers at the University of South Carolina's Arnold School of Public Health have reported that repurposing exis ...
      Written By: Nouran Amin
      1
      OCT 23, 2019
      Immunology
      Treating Celiac Disease May Be Possible
      Treating Celiac Disease May Be Possible
      Delivering gluten to the body in a friendly, harmless package may be the way for people with celiac disease to finally h ...
      Written By: Kara Marker
      1
      OCT 22, 2019
      Cancer
      Using senolytics to treat cancer
      Using senolytics to treat cancer
      New research published in Nature Metabolism proposes using an already existing drug – a cardiac glycoside called o ...
      Written By: Kathryn DeMuth Sullivan
      2
      OCT 22, 2019
      Technology
      New Encapsulation Technology
      New Encapsulation Technology
      Research at the University of Waterloo has concluded new encapsulation technology that can offer an inexpensive, and eff ...
      Written By: Nouran Amin
      1
    NOV 06, 2019
    Drug Discovery & Development
    Possible New Drug Targets for Glioblastoma
    Possible New Drug Targets for Glioblastoma
    Scientists at Karolinska Institutet in Sweden were able to pinpoint 10 tumor-specific potential drug targets for the fat ...
    Written By: Nouran Amin
    3
    NOV 04, 2019
    Drug Discovery & Development
    Gene Variant Could Be a Therapeutic Target For Alzheimer Disease
    Gene Variant Could Be a Therapeutic Target For Alzheimer Disease
    A variation in genetics for an individual at high-risk for Alzheimer development has defied the odds for being dementia- ...
    Written By: Nouran Amin
    2
    NOV 04, 2019
    Drug Discovery & Development
    How Fluorescent Probes Can Enhance Drug Delivery
    How Fluorescent Probes Can Enhance Drug Delivery
    Researchers at Cornell University are working on improving the trial-and-error process that is implicated in finding eff ...
    Written By: Nouran Amin
    2
    NOV 03, 2019
    Cell & Molecular Biology
    Researchers Identify New Cellular Signaling Mechanisms
    Researchers Identify New Cellular Signaling Mechanisms
    Molecules and drugs move among cells and bind to receptors on the cell surface, which can initiate a cascade of reaction ...
    Written By: Carmen Leitch
    1
    NOV 01, 2019
    Health & Medicine
    FDA Cautions Against Cannabis Use During Pregnancy
    FDA Cautions Against Cannabis Use During Pregnancy
    A recent article published by NPR addresses the rapidly growing number of females using cannabis during pregnancy. Those ...
    Written By: C Reardon
    1
     
     
  • NOV 01, 2019
    Chemistry & Physics
    Cancer Therapy Agents Inspired by Solar Technology
    Cancer Therapy Agents Inspired by Solar Technology
    In a recent study, a group of biomedical researchers at Michigan State University developed a new platform for tweaking ...
    Written By: Daniel Duan
    2
    OCT 31, 2019
    Cancer
    Unpacking lactate's role in the Warburg effect
    Unpacking lactate's role in the Warburg effect
    In a recent issue of Nature, the findings of one study made a particularly big splash: how and why cancer cells use ener ...
    Written By: Kathryn DeMuth Sullivan
    1
    OCT 31, 2019
    Genetics & Genomics
    Familial Alzheimer's Gene Found to Regulate Nerve Development
    Familial Alzheimer's Gene Found to Regulate Nerve Development
    An international team of scientists has now identified a process that plays a critical role in the growth of one part of ...
    Written By: Carmen Leitch
    1
    OCT 30, 2019
    Cancer
    How caloric restriction mimetics might prove helpful for cancer treatments
    How caloric restriction mimetics might prove helpful for cancer treatments
    The benefits of fasting have been known to scientists and medical professionals for some time now, however for many, the ...
    Written By: Kathryn DeMuth Sullivan
    1
    OCT 30, 2019
    Drug Discovery & Development
    Investigating a common therapeutic in ADHD treatment
    Investigating a common therapeutic in ADHD treatment
    Attention-Deficit Hyperactivity Disorder (ADHD) is a widespread condition with variable underlying causes. A common ther ...
    Written By: Nouran Amin
    1
     
     
  • OCT 30, 2019
    Drug Discovery & Development
    Can Aspirin Prevent a Brain Bleed?
    Can Aspirin Prevent a Brain Bleed?
    Can aspirin prevent a brain bleed? To answer the questions, researchers rummaged through a database system looking to se ...
    Written By: Nouran Amin
    1
    OCT 30, 2019
    Drug Discovery & Development
    Advancing Nanocontainers for Drug Delivery
    Advancing Nanocontainers for Drug Delivery
    Nanocontainers work by delivering drugs to a localized region in the body, many chemotherapeutics work in that matter. T ...
    Written By: Nouran Amin
    1
    OCT 30, 2019
    Drug Discovery & Development
    Developing Animal-Free Neurotoxin Testing
    Developing Animal-Free Neurotoxin Testing
    The need to assess a group of deadly neurotoxins without turning to animal-testing may soon be a possibility. A new anim ...
    Written By: Nouran Amin
    1
    OCT 29, 2019
    Microbiology
    Antibody Discovered That May be the Key to a Universal Flu Vaccine
    Antibody Discovered That May be the Key to a Universal Flu Vaccine
    Instead of designing a new flu vaccine every year, researchers have made a breakthrough that may lead to a single vaccin ...
    Written By: Carmen Leitch
    1
    OCT 28, 2019
    Genetics & Genomics
    Super-Resolution Microscopy Reveals How DNA Damage is Repaired
    Super-Resolution Microscopy Reveals How DNA Damage is Repaired
    People that don't carry functional copies of these proteins are more likely to get diseases that arise from unstable DNA ...
    Written By: Carmen Leitch
    1
     
     
  • OCT 28, 2019
    Neuroscience
    First Drug to Slow Progression of Alzheimer's Shows Promise
    First Drug to Slow Progression of Alzheimer's Shows Promise
    An estimated 5.8 million people living in the US have Alzheimer’s disease. Currently, no cure is available and any ...
    Written By: Annie Lennon
    1
    OCT 26, 2019
    Genetics & Genomics
    Gates Foundation and NIH Pledge $200 Million for Gene Therapies in Africa
    Gates Foundation and NIH Pledge $200 Million for Gene Therapies in Africa
    Over the next four years, the National Institutes of Health and the Bill and Melinda Gates Foundation plan to each inves ...
    Written By: Annie Lennon
    2
    OCT 25, 2019
    Drug Discovery & Development
    Fecal Transplants Could Treat Irritable Bowel Syndrome
    Fecal Transplants Could Treat Irritable Bowel Syndrome
    According to the American College of Gastroenterology, between 10 and 15% of Americans have Irritable Bowel Syndrome (IB ...
    Written By: Annie Lennon
    1
    OCT 25, 2019
    Drug Discovery & Development
    Novel Therapeutic For Eradicating The Flu Virus
    Novel Therapeutic For Eradicating The Flu Virus
    Public Health officials have long warned about pandemic pathogens flying fast around the world. One virus already spread ...
    Written By: Nouran Amin
    1
    OCT 24, 2019
    Drug Discovery & Development
    Converting Wood into Pharmaceutical Compounds
    Converting Wood into Pharmaceutical Compounds
    Producing toxic byproducts during the making of pharmaceuticals remains a challenge in the drug manufacturing industry. ...
    Written By: Nouran Amin
    1
     
     
  • OCT 23, 2019
    Drug Discovery & Development
    Treating Gulf-War Illness with Anti-Viral Drugs
    Treating Gulf-War Illness with Anti-Viral Drugs
    Researchers at the University of South Carolina's Arnold School of Public Health have reported that repurposing exis ...
    Written By: Nouran Amin
    1
    OCT 23, 2019
    Immunology
    Treating Celiac Disease May Be Possible
    Treating Celiac Disease May Be Possible
    Delivering gluten to the body in a friendly, harmless package may be the way for people with celiac disease to finally h ...
    Written By: Kara Marker
    1
    OCT 22, 2019
    Cancer
    Using senolytics to treat cancer
    Using senolytics to treat cancer
    New research published in Nature Metabolism proposes using an already existing drug – a cardiac glycoside called o ...
    Written By: Kathryn DeMuth Sullivan
    2
    OCT 22, 2019
    Technology
    New Encapsulation Technology
    New Encapsulation Technology
    Research at the University of Waterloo has concluded new encapsulation technology that can offer an inexpensive, and eff ...
    Written By: Nouran Amin
    1
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