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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • OCT 22, 2019
      Technology
      Machine-Learning and Epigenetics Drug Discovery
      Machine-Learning and Epigenetics Drug Discovery
      Machine learning is known for detecting patterns seen in complex data—such uniqueness has proven it roles in healt ...
      Written By: Nouran Amin
      1
      OCT 22, 2019
      Drug Discovery & Development
      Metformin Offers No Muscle Mass Gain for Older Adults
      Metformin Offers No Muscle Mass Gain for Older Adults
      A clinical trial initiated by Researchers at the University of Kentucky began a clinical study to address the long-held ...
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      OCT 22, 2019
      Drug Discovery & Development
      Common Therapeutic Can Treat Bleeding Associated with Traumatic Brain Injury
      Common Therapeutic Can Treat Bleeding Associated with Traumatic Brain Injury
      An inexpensive and accessible drug was found to reduce rates of mortality associated with traumatic brain injury (TBI) p ...
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      OCT 21, 2019
      Drug Discovery & Development
      Effective Vaccines for Lyme Disease?
      Effective Vaccines for Lyme Disease?
      Currently, there are no effective vaccines available for the presentation of Lyme disease. The only preventive efforts p ...
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      2
      OCT 21, 2019
      Drug Discovery & Development
      Therapeutic Targets Inflammation Associated with Genetic Heart Disease
      Therapeutic Targets Inflammation Associated with Genetic Heart Disease
      Often times when young athletes collapse during the game it is due to sudden cardiac death as a result of the inherited ...
      Written By: Nouran Amin
      1
      OCT 19, 2019
      Microbiology
      Learning More About Toxoplasmosis
      Learning More About Toxoplasmosis
      Around a third of the global population, including 40 million Americans are thought to be infected with a parasite calle ...
      Written By: Carmen Leitch
      2
      OCT 19, 2019
      Cancer
      An alternative for immunotherapy-resistant cancer patients
      An alternative for immunotherapy-resistant cancer patients
      A twist to traditional immunotherapies could help cancer patients’ immune systems better detect cancer cells, maki ...
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      OCT 18, 2019
      Genetics & Genomics
      Rare Gene Mutation Prevents Memory Problems Brought on by Sleep Deprivation
      Rare Gene Mutation Prevents Memory Problems Brought on by Sleep Deprivation
      A few rare people can get by with less sleep than the rest of us; after only four to six hours they are well-rested.
      Written By: Carmen Leitch
      1
      OCT 16, 2019
      Drug Discovery & Development
      Common Drug May Prevent Thousands Deaths from Head Injury
      Common Drug May Prevent Thousands Deaths from Head Injury
      Each year, there are over 60 million new cases of traumatic brain injury (TBI). Mostly caused by road traffic crashes an ...
      Written By: Annie Lennon
      2
      OCT 16, 2019
      Drug Discovery & Development
      Diabetes: The next-generation therapy
      Diabetes: The next-generation therapy
      A publication in Nature Communications describes a therapeutic that can avoid the side-effects of insulin in diabetic tr ...
      Written By: Nouran Amin
      1
      OCT 16, 2019
      Drug Discovery & Development
      Nanomesh Development Advances Drug Delivery's Fight Against Antibiotic-Resistance
      Nanomesh Development Advances Drug Delivery's Fight Against Antibiotic-Resistance
      As concern over medication-resistant bacteria grows, researchers at Flinders University have now fabricated nanomeshes a ...
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      1
      OCT 15, 2019
      Drug Discovery & Development
      Therapeutic To Treat The Detrimental Effects of Marijuana
      Therapeutic To Treat The Detrimental Effects of Marijuana
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      OCT 15, 2019
      Cannabis Sciences
      CBD Extract for Cannabis Addiction
      CBD Extract for Cannabis Addiction
      Some people believe the secret to curing a hangover is to drink more alcohol the morning after a night of binge drinking ...
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      OCT 15, 2019
      Microbiology
      The Antimicrobial Power of Mucus is Revealed
      The Antimicrobial Power of Mucus is Revealed
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      OCT 14, 2019
      Drug Discovery & Development
      Injectable Drug reverses symptoms of liver disease in people with HIV
      Injectable Drug reverses symptoms of liver disease in people with HIV
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      OCT 14, 2019
      Drug Discovery & Development
      Aspirin May Reduce Effects of Air Pollution on Lungs
      Aspirin May Reduce Effects of Air Pollution on Lungs
      New research findings, published in the American Journal of Respiratory and Critical Care Medicine, are the first to sug ...
      Written By: Nouran Amin
      1
      OCT 13, 2019
      Cell & Molecular Biology
      Discovery of Cell's Mechanism for Sensing Oxygen Wins Nobel
      Discovery of Cell's Mechanism for Sensing Oxygen Wins Nobel
      It may be possible to attack cancer or treat anemia or other diseases by interfering with the cells' ability to sense ox ...
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      1
      OCT 10, 2019
      Health & Medicine
      All you need to know about Orphan Drugs
      All you need to know about Orphan Drugs
      Orphan drugs are medicinal products intended for the diagnosis, prevention, or treatment of very rare life-threatening d ...
      Written By: Liat Ben-Senior
      1
      OCT 10, 2019
      Genetics & Genomics
      A Cancer-Promoting Mutation is Found in 'Junk' DNA
      A Cancer-Promoting Mutation is Found in 'Junk' DNA
      A huge amount of our genome does not code for protein, but it can impact physiology in other ways.
      Written By: Carmen Leitch
      1
      OCT 10, 2019
      Genetics & Genomics
      Gene-Editing Breakthrough for Cervical Cancer
      Gene-Editing Breakthrough for Cervical Cancer
      Researchers at the The Menzies Health Institute Queensland have found a way to use gene therapy CRISPR-Cas9 to treat cer ...
      Written By: Annie Lennon
      2
      OCT 09, 2019
      Drug Discovery & Development
      Tailor-made Drug for Girl with Rare Genetic Disease
      Tailor-made Drug for Girl with Rare Genetic Disease
      Researchers have used personalized medicine to develop a tailor-made genetic treatment for a girl diagnosed with a rare ...
      Written By: Annie Lennon
      2
      OCT 09, 2019
      Drug Discovery & Development
      Drug Increases Survival Rates for Heart Failure Patients
      Drug Increases Survival Rates for Heart Failure Patients
      Scientists have demonstrated in preclinical studies that a drug called ‘Aliskiren’ works by inhibiting the a ...
      Written By: Nouran Amin
      1
      OCT 08, 2019
      Microbiology
      Potential New Antibiotic Discovered in Soil-Dwelling Microbe
      Potential New Antibiotic Discovered in Soil-Dwelling Microbe
      Many of our best antibiotics have come from microbes, which have to use them to battle other microorganisms in a struggl ...
      Written By: Carmen Leitch
      1
      OCT 07, 2019
      Clinical & Molecular DX
      The Three Common Herbs Combating High Blood Pressure: Molecular Mechanism Revealed
      The Three Common Herbs Combating High Blood Pressure: Molecular Mechanism Revealed
      Hypertension is also known as high blood pressure is a serious condition. According to the Centers for Disease Cont ...
      Written By: Nupur Srivastava
      1
    OCT 22, 2019
    Technology
    Machine-Learning and Epigenetics Drug Discovery
    Machine-Learning and Epigenetics Drug Discovery
    Machine learning is known for detecting patterns seen in complex data—such uniqueness has proven it roles in healt ...
    Written By: Nouran Amin
    1
    OCT 22, 2019
    Drug Discovery & Development
    Metformin Offers No Muscle Mass Gain for Older Adults
    Metformin Offers No Muscle Mass Gain for Older Adults
    A clinical trial initiated by Researchers at the University of Kentucky began a clinical study to address the long-held ...
    Written By: Nouran Amin
    1
    OCT 22, 2019
    Drug Discovery & Development
    Common Therapeutic Can Treat Bleeding Associated with Traumatic Brain Injury
    Common Therapeutic Can Treat Bleeding Associated with Traumatic Brain Injury
    An inexpensive and accessible drug was found to reduce rates of mortality associated with traumatic brain injury (TBI) p ...
    Written By: Nouran Amin
    1
    OCT 21, 2019
    Drug Discovery & Development
    Effective Vaccines for Lyme Disease?
    Effective Vaccines for Lyme Disease?
    Currently, there are no effective vaccines available for the presentation of Lyme disease. The only preventive efforts p ...
    Written By: Nouran Amin
    2
    OCT 21, 2019
    Drug Discovery & Development
    Therapeutic Targets Inflammation Associated with Genetic Heart Disease
    Therapeutic Targets Inflammation Associated with Genetic Heart Disease
    Often times when young athletes collapse during the game it is due to sudden cardiac death as a result of the inherited ...
    Written By: Nouran Amin
    1
     
     
  • OCT 19, 2019
    Microbiology
    Learning More About Toxoplasmosis
    Learning More About Toxoplasmosis
    Around a third of the global population, including 40 million Americans are thought to be infected with a parasite calle ...
    Written By: Carmen Leitch
    2
    OCT 19, 2019
    Cancer
    An alternative for immunotherapy-resistant cancer patients
    An alternative for immunotherapy-resistant cancer patients
    A twist to traditional immunotherapies could help cancer patients’ immune systems better detect cancer cells, maki ...
    Written By: Kathryn DeMuth Sullivan
    2
    OCT 18, 2019
    Genetics & Genomics
    Rare Gene Mutation Prevents Memory Problems Brought on by Sleep Deprivation
    Rare Gene Mutation Prevents Memory Problems Brought on by Sleep Deprivation
    A few rare people can get by with less sleep than the rest of us; after only four to six hours they are well-rested.
    Written By: Carmen Leitch
    1
    OCT 16, 2019
    Drug Discovery & Development
    Common Drug May Prevent Thousands Deaths from Head Injury
    Common Drug May Prevent Thousands Deaths from Head Injury
    Each year, there are over 60 million new cases of traumatic brain injury (TBI). Mostly caused by road traffic crashes an ...
    Written By: Annie Lennon
    2
    OCT 16, 2019
    Drug Discovery & Development
    Diabetes: The next-generation therapy
    Diabetes: The next-generation therapy
    A publication in Nature Communications describes a therapeutic that can avoid the side-effects of insulin in diabetic tr ...
    Written By: Nouran Amin
    1
     
     
  • OCT 16, 2019
    Drug Discovery & Development
    Nanomesh Development Advances Drug Delivery's Fight Against Antibiotic-Resistance
    Nanomesh Development Advances Drug Delivery's Fight Against Antibiotic-Resistance
    As concern over medication-resistant bacteria grows, researchers at Flinders University have now fabricated nanomeshes a ...
    Written By: Nouran Amin
    1
    OCT 15, 2019
    Drug Discovery & Development
    Therapeutic To Treat The Detrimental Effects of Marijuana
    Therapeutic To Treat The Detrimental Effects of Marijuana
    As U.S. states continue to legalize the use of marijuana, so is the number of American women using cannabis before becom ...
    Written By: Nouran Amin
    1
    OCT 15, 2019
    Cannabis Sciences
    CBD Extract for Cannabis Addiction
    CBD Extract for Cannabis Addiction
    Some people believe the secret to curing a hangover is to drink more alcohol the morning after a night of binge drinking ...
    Written By: Kara Marker
    1
    OCT 15, 2019
    Microbiology
    The Antimicrobial Power of Mucus is Revealed
    The Antimicrobial Power of Mucus is Revealed
    We produce several liters of mucus every day to cover more than 200 square meters in the human body.
    Written By: Carmen Leitch
    2
    OCT 14, 2019
    Drug Discovery & Development
    Injectable Drug reverses symptoms of liver disease in people with HIV
    Injectable Drug reverses symptoms of liver disease in people with HIV
    In a study conducted by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Cancer Instit ...
    Written By: Nouran Amin
    1
     
     
  • OCT 14, 2019
    Drug Discovery & Development
    Aspirin May Reduce Effects of Air Pollution on Lungs
    Aspirin May Reduce Effects of Air Pollution on Lungs
    New research findings, published in the American Journal of Respiratory and Critical Care Medicine, are the first to sug ...
    Written By: Nouran Amin
    1
    OCT 13, 2019
    Cell & Molecular Biology
    Discovery of Cell's Mechanism for Sensing Oxygen Wins Nobel
    Discovery of Cell's Mechanism for Sensing Oxygen Wins Nobel
    It may be possible to attack cancer or treat anemia or other diseases by interfering with the cells' ability to sense ox ...
    Written By: Carmen Leitch
    1
    OCT 10, 2019
    Health & Medicine
    All you need to know about Orphan Drugs
    All you need to know about Orphan Drugs
    Orphan drugs are medicinal products intended for the diagnosis, prevention, or treatment of very rare life-threatening d ...
    Written By: Liat Ben-Senior
    1
    OCT 10, 2019
    Genetics & Genomics
    A Cancer-Promoting Mutation is Found in 'Junk' DNA
    A Cancer-Promoting Mutation is Found in 'Junk' DNA
    A huge amount of our genome does not code for protein, but it can impact physiology in other ways.
    Written By: Carmen Leitch
    1
    OCT 10, 2019
    Genetics & Genomics
    Gene-Editing Breakthrough for Cervical Cancer
    Gene-Editing Breakthrough for Cervical Cancer
    Researchers at the The Menzies Health Institute Queensland have found a way to use gene therapy CRISPR-Cas9 to treat cer ...
    Written By: Annie Lennon
    2
     
     
  • OCT 09, 2019
    Drug Discovery & Development
    Tailor-made Drug for Girl with Rare Genetic Disease
    Tailor-made Drug for Girl with Rare Genetic Disease
    Researchers have used personalized medicine to develop a tailor-made genetic treatment for a girl diagnosed with a rare ...
    Written By: Annie Lennon
    2
    OCT 09, 2019
    Drug Discovery & Development
    Drug Increases Survival Rates for Heart Failure Patients
    Drug Increases Survival Rates for Heart Failure Patients
    Scientists have demonstrated in preclinical studies that a drug called ‘Aliskiren’ works by inhibiting the a ...
    Written By: Nouran Amin
    1
    OCT 08, 2019
    Microbiology
    Potential New Antibiotic Discovered in Soil-Dwelling Microbe
    Potential New Antibiotic Discovered in Soil-Dwelling Microbe
    Many of our best antibiotics have come from microbes, which have to use them to battle other microorganisms in a struggl ...
    Written By: Carmen Leitch
    1
    OCT 07, 2019
    Clinical & Molecular DX
    The Three Common Herbs Combating High Blood Pressure: Molecular Mechanism Revealed
    The Three Common Herbs Combating High Blood Pressure: Molecular Mechanism Revealed
    Hypertension is also known as high blood pressure is a serious condition. According to the Centers for Disease Cont ...
    Written By: Nupur Srivastava
    1
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