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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • JUN 06, 2019
      Drug Discovery & Development
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      Drug Regimen Improves Clinical Outcomes for Kidney Transplant Patients
      Recent preliminary clinical trial results indicate the immunosuppressive drug belatacept can safely and effectively trea ...
      Written By: Nouran Amin
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      JUN 05, 2019
      Genetics & Genomics
      Clinical Trials Aim to Improve Therapeutics with Genomic Data
      Clinical Trials Aim to Improve Therapeutics with Genomic Data
      Scientists now have access to vast amounts of human genetic data. Now the NIH wants to put that data to use.
      Written By: Carmen Leitch
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      JUN 05, 2019
      Drug Discovery & Development
      Novel Strategy for Drug Discovery and Development
      Novel Strategy for Drug Discovery and Development
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      JUN 05, 2019
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      Anti-Diabetic Drug Reduces Anxiety-Like Symptoms
      Anti-Diabetic Drug Reduces Anxiety-Like Symptoms
      In a study published in the Journal of Neuroscience, an antidiabetic drug called metformin was found to alleviate anxiet ...
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      JUN 03, 2019
      Microbiology
      Manuka Honey Kills Cystic Fibrosis Pathogens in Culture
      Manuka Honey Kills Cystic Fibrosis Pathogens in Culture
      Manuka honey is recognized as a natural antimicrobial agent, and has been used in folk medicines for thousands of years.
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      JUN 02, 2019
      Drug Discovery & Development
      Drug Treatment for Social Anxiety Proves Insufficient
      Drug Treatment for Social Anxiety Proves Insufficient
      In a Japanese study published in the journal Psychotherapy and Psychosomatics, antidepressant drugs targeted for treatin ...
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      MAY 24, 2019
      Drug Discovery & Development
      First Anticoagulant Approved for Pediatric Patients to Treat Potentially Life-Threatening Blood Clots
      First Anticoagulant Approved for Pediatric Patients to Treat Potentially Life-Threatening Blood Clots
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      MAY 24, 2019
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      MAY 24, 2019
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      First PI3K Inhibitor for Breast Cancer
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      MAY 24, 2019
      Drug Discovery & Development
      Potential Drug Target for Anxiety
      Potential Drug Target for Anxiety
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      MAY 24, 2019
      Drug Discovery & Development
      New Therapeutic Target for Depression
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      MAY 23, 2019
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      MAY 23, 2019
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      Long-Lasting Worms Inspires Anti-Aging Drugs
      Long-Lasting Worms Inspires Anti-Aging Drugs
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      MAY 23, 2019
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      MAY 23, 2019
      Drug Discovery & Development
      Repurposing Cancer Drug for Treating Brain Aneurysms
      Repurposing Cancer Drug for Treating Brain Aneurysms
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      MAY 23, 2019
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      MAY 22, 2019
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      MAY 21, 2019
      Drug Discovery & Development
      New Viable Drug Target for Prostate Cancer
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      MAY 21, 2019
      Drug Discovery & Development
      A New Class Of Depression Medication
      A New Class Of Depression Medication
      The National Institutes of Health (NIH) estimate that over 17 million adults in the US have had at least one major depre ...
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      1
      MAY 21, 2019
      Drug Discovery & Development
      Benralizumab not effective reducing exacerbations of COPD
      Benralizumab not effective reducing exacerbations of COPD
      According to the American Lung Association, chronic obstructive pulmonary disease (COPD) is the third leading cause of d ...
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      MAY 18, 2019
      Drug Discovery & Development
      How a Cancer Drug Inhibits DNA Repair in Cancer Cells
      How a Cancer Drug Inhibits DNA Repair in Cancer Cells
      In a study published in the journal Science Translational Medicine, combing a certain cancer drug with other agents coul ...
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      MAY 12, 2019
      Drug Discovery & Development
      Potential of Statins to Treat Multiple Sclerosis
      Potential of Statins to Treat Multiple Sclerosis
      A widely used therapeutic statin, simvastatin, which is intended to treat cholesterol was found to be medically benefici ...
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      MAY 08, 2019
      Drug Discovery & Development
      Drug for Huntington Disease Successfully Lowers Culprit Protein
      Drug for Huntington Disease Successfully Lowers Culprit Protein
      In a study published in the New England Journal of Medicine, a drug for the first time was shown to successfully lower t ...
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      MAY 08, 2019
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      Promising treatment for severe dry eye disease
      Promising treatment for severe dry eye disease
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    JUN 06, 2019
    Drug Discovery & Development
    Drug Regimen Improves Clinical Outcomes for Kidney Transplant Patients
    Drug Regimen Improves Clinical Outcomes for Kidney Transplant Patients
    Recent preliminary clinical trial results indicate the immunosuppressive drug belatacept can safely and effectively trea ...
    Written By: Nouran Amin
    1
    JUN 05, 2019
    Genetics & Genomics
    Clinical Trials Aim to Improve Therapeutics with Genomic Data
    Clinical Trials Aim to Improve Therapeutics with Genomic Data
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    Written By: Carmen Leitch
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    JUN 05, 2019
    Drug Discovery & Development
    Novel Strategy for Drug Discovery and Development
    Novel Strategy for Drug Discovery and Development
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    Written By: Nouran Amin
    1
    JUN 05, 2019
    Drug Discovery & Development
    Anti-Diabetic Drug Reduces Anxiety-Like Symptoms
    Anti-Diabetic Drug Reduces Anxiety-Like Symptoms
    In a study published in the Journal of Neuroscience, an antidiabetic drug called metformin was found to alleviate anxiet ...
    Written By: Nouran Amin
    1
    JUN 03, 2019
    Microbiology
    Manuka Honey Kills Cystic Fibrosis Pathogens in Culture
    Manuka Honey Kills Cystic Fibrosis Pathogens in Culture
    Manuka honey is recognized as a natural antimicrobial agent, and has been used in folk medicines for thousands of years.
    Written By: Carmen Leitch
    1
     
     
  • JUN 02, 2019
    Drug Discovery & Development
    Drug Treatment for Social Anxiety Proves Insufficient
    Drug Treatment for Social Anxiety Proves Insufficient
    In a Japanese study published in the journal Psychotherapy and Psychosomatics, antidepressant drugs targeted for treatin ...
    Written By: Nouran Amin
    2
    MAY 24, 2019
    Drug Discovery & Development
    First Anticoagulant Approved for Pediatric Patients to Treat Potentially Life-Threatening Blood Clots
    First Anticoagulant Approved for Pediatric Patients to Treat Potentially Life-Threatening Blood Clots
    The approval of the drug Fragmin, an anti-coagulant subcutaneous use, will seek to reduce the recurrence of symptomatic ...
    Written By: Nouran Amin
    2
    MAY 24, 2019
    Cardiology
    Hallucinogens As Mental Health Treatments
    Hallucinogens As Mental Health Treatments
    In a time when once-demonized substances are being recognized for their potential health benefits, what role should psyc ...
    Written By: Abbie Arce
    1
    MAY 24, 2019
    Drug Discovery & Development
    First PI3K Inhibitor for Breast Cancer
    First PI3K Inhibitor for Breast Cancer
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    Written By: Nouran Amin
    1
    MAY 24, 2019
    Drug Discovery & Development
    Potential Drug Target for Anxiety
    Potential Drug Target for Anxiety
    In a study published in JAMA Psychiatry, researchers have identified new genetic contributors to anxiety and stress-rela ...
    Written By: Nouran Amin
    1
     
     
  • MAY 24, 2019
    Drug Discovery & Development
    New Therapeutic Target for Depression
    New Therapeutic Target for Depression
    In a study published in the Journal of Psychopharmacology, a new drug target for the treatment of depression has been id ...
    Written By: Nouran Amin
    1
    MAY 23, 2019
    Drug Discovery & Development
    Rapamycin and Anti-Aging
    Rapamycin and Anti-Aging
    Rapamycin was considered a wonder drug upon its discovery three decades ago when it was isolated from soil bacteria. It ...
    Written By: Nouran Amin
    2
    MAY 23, 2019
    Drug Discovery & Development
    Long-Lasting Worms Inspires Anti-Aging Drugs
    Long-Lasting Worms Inspires Anti-Aging Drugs
    Researchers have recently discovered that aging in nematodes may be partially controlled and can be therapeutically reve ...
    Written By: Nouran Amin
    1
    MAY 23, 2019
    Drug Discovery & Development
    Miracle Drug for Rare Genetic Disease Causes Price Concerns
    Miracle Drug for Rare Genetic Disease Causes Price Concerns
    A newly approved “miracle drug” called Zolgensma will be used to treat children with spinal muscular atrophy ...
    Written By: Nouran Amin
    1
    MAY 23, 2019
    Drug Discovery & Development
    Repurposing Cancer Drug for Treating Brain Aneurysms
    Repurposing Cancer Drug for Treating Brain Aneurysms
    Brain aneurysms is a result of a bulging blood vessel due to a weakness in the blood vessel wall. When the blood passes ...
    Written By: Nouran Amin
    1
     
     
  • MAY 23, 2019
    Microbiology
    Civil War Folk Remedies are Effective Against Drug-resistant Pathogens
    Civil War Folk Remedies are Effective Against Drug-resistant Pathogens
    Extracts from three plants were active against some of today's worst drug-resistant bacterial pathogens that infect woun ...
    Written By: Carmen Leitch
    2
    MAY 22, 2019
    Drug Discovery & Development
    Potential Drug Target for Stroke Patients
    Potential Drug Target for Stroke Patients
    In a study published in Science, a proton-activated chloride channel (PAC) may serve as a drug target to protect against ...
    Written By: Nouran Amin
    1
    MAY 21, 2019
    Drug Discovery & Development
    New Viable Drug Target for Prostate Cancer
    New Viable Drug Target for Prostate Cancer
    In the research community, MYC is historically known to be a difficult oncogene to target in cancer therapy. However, a ...
    Written By: Nouran Amin
    1
    MAY 21, 2019
    Drug Discovery & Development
    A New Class Of Depression Medication
    A New Class Of Depression Medication
    The National Institutes of Health (NIH) estimate that over 17 million adults in the US have had at least one major depre ...
    Written By: Abbie Arce
    1
    MAY 21, 2019
    Drug Discovery & Development
    Benralizumab not effective reducing exacerbations of COPD
    Benralizumab not effective reducing exacerbations of COPD
    According to the American Lung Association, chronic obstructive pulmonary disease (COPD) is the third leading cause of d ...
    Written By: Nouran Amin
    1
     
     
  • MAY 18, 2019
    Drug Discovery & Development
    How a Cancer Drug Inhibits DNA Repair in Cancer Cells
    How a Cancer Drug Inhibits DNA Repair in Cancer Cells
    In a study published in the journal Science Translational Medicine, combing a certain cancer drug with other agents coul ...
    Written By: Nouran Amin
    1
    MAY 12, 2019
    Drug Discovery & Development
    Potential of Statins to Treat Multiple Sclerosis
    Potential of Statins to Treat Multiple Sclerosis
    A widely used therapeutic statin, simvastatin, which is intended to treat cholesterol was found to be medically benefici ...
    Written By: Nouran Amin
    1
    MAY 08, 2019
    Drug Discovery & Development
    Drug for Huntington Disease Successfully Lowers Culprit Protein
    Drug for Huntington Disease Successfully Lowers Culprit Protein
    In a study published in the New England Journal of Medicine, a drug for the first time was shown to successfully lower t ...
    Written By: Nouran Amin
    1
    MAY 08, 2019
    Drug Discovery & Development
    Promising treatment for severe dry eye disease
    Promising treatment for severe dry eye disease
    In a study published in Translational Vision Science and Technology, a phase I/II clinical trial involving a novel enzym ...
    Written By: Nouran Amin
    1
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