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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • JUN 19, 2019
      Drug Discovery & Development
      Experimental Drug Encourages Bone Growth in Children with Dwarfism
      Experimental Drug Encourages Bone Growth in Children with Dwarfism
      An experimental drug called vosoritide, alters certain proteins that block bone growth, which allowed the average annual ...
      Written By: Nouran Amin
      1
      JUN 19, 2019
      Drug Discovery & Development
      Antidepressants May Impair Empathy
      Antidepressants May Impair Empathy
      Depression is tagged with strong impairments of social functioning. Until recently, researchers believed that acute depr ...
      Written By: Nouran Amin
      1
      JUN 18, 2019
      Drug Discovery & Development
      Drug Compound May Treat Common Genetic Kidney Disease
      Drug Compound May Treat Common Genetic Kidney Disease
      Researchers from the University of Sheffield in collaboration with Glasgow-based biotech company Mironid, have developed ...
      Written By: Nouran Amin
      2
      JUN 18, 2019
      Health & Medicine
      Scientists Identify Which Gut Bacteria Interfere With Parkinson's Treatment
      Scientists Identify Which Gut Bacteria Interfere With Parkinson's Treatment
      A new study from a team of Harvard scientists discovered one of the first distinct examples of how gut bacteria can inte ...
      Written By: Tiffany Dazet
      1
      JUN 17, 2019
      Cell & Molecular Biology
      Researchers Discover Molecule That May Cause Lyme Disease Symptoms
      Researchers Discover Molecule That May Cause Lyme Disease Symptoms
      Scientists at Virginia Tech have found a molecule that can potentially improve the diagnosis and treatment of Lyme disea ...
      Written By: Carmen Leitch
      3
      JUN 17, 2019
      Drug Discovery & Development
      Promising Hypertension Drug for Alzheimer Disease
      Promising Hypertension Drug for Alzheimer Disease
      In a study led by the American Heart Association, the blood pressure drug nilvadipine (a calcium channel blocker) was fo ...
      Written By: Nouran Amin
      2
      JUN 17, 2019
      Drug Discovery & Development
      Drug Delays Type 1 Diabetes in High Risk Individuals
      Drug Delays Type 1 Diabetes in High Risk Individuals
      An immunotherapeutic, involving anti-CD3 monoclonal antibody (teplizumab), was seen to slow down the progression to clin ...
      Written By: Nouran Amin
      1
      JUN 17, 2019
      Drug Discovery & Development
      Breakthrough Synthesis Advances Potent Anti-Cancer Agent
      Breakthrough Synthesis Advances Potent Anti-Cancer Agent
      What is now known as a "landmark in drug discovery", Harvard chemists have succeeded in synthesizing halichond ...
      Written By: Nouran Amin
      1
      JUN 16, 2019
      Health & Medicine
      Remember Joe Camel? E-cigarette cartoon ads increase the chances of vaping
      Remember Joe Camel? E-cigarette cartoon ads increase the chances of vaping
      Do you remember the infamous "Joe Camel" advertisements for cigarettes back in the 1980s and 90s? These ads su ...
      Written By: Dr. Nina Lichtenberg
      1
      JUN 16, 2019
      Microbiology
      Vulnerability in Famously Hard-to-Target Viruses is Identified
      Vulnerability in Famously Hard-to-Target Viruses is Identified
      The cold virus is famously difficult to target with drugs because it can mutate rapidly.
      Written By: Carmen Leitch
      1
      JUN 15, 2019
      Cell & Molecular Biology
      Understanding and Treating the Mechanisms That Drive Rheumatoid Arthritis
      Understanding and Treating the Mechanisms That Drive Rheumatoid Arthritis
      In RA, cells of the immune system mistakenly attack the joints, and cause the painful inflammation that is a hallmark of ...
      Written By: Carmen Leitch
      1
      JUN 14, 2019
      Drug Discovery & Development
      Attaching a removable lock to an arthritis drug
      Attaching a removable lock to an arthritis drug
      A study published in PLOS Biology suggests that attaching a removable lock to an arthritis drug can increase its effecti ...
      Written By: Nouran Amin
      1
      JUN 13, 2019
      Health & Medicine
      Formation of Habitual Cannabis Use Drives Addiction
      Formation of Habitual Cannabis Use Drives Addiction
      According to a new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier, shift ...
      Written By: C Reardon
      1
      JUN 13, 2019
      Health & Medicine
      Can CBD Be Used to Treat Anxiety?
      Can CBD Be Used to Treat Anxiety?
      A 2019 study published on the National Center for Biotechnology Information showed that Cannabidiol might benefit a ...
      Written By: C Reardon
      1 1
      JUN 13, 2019
      Cancer
      This Molecule Compound Reduces Chemo Resistance
      This Molecule Compound Reduces Chemo Resistance
      Drug resistance is a major hindrance to cancer treatment. Researchers from Duke University, MIT and the University of Rh ...
      Written By: Julia Travers
      1
      JUN 12, 2019
      Drug Discovery & Development
      Injectable Hydrogel Recruits Chemotherapeutics to Tumor Site
      Injectable Hydrogel Recruits Chemotherapeutics to Tumor Site
      Targeting tumor cells while avoiding harming healthy tissue remains a growing central challenge in the field of chemothe ...
      Written By: Nouran Amin
      1
      JUN 12, 2019
      Drug Discovery & Development
      Sustainable Production of Opiate Antidotes
      Sustainable Production of Opiate Antidotes
      According to the National Center for Health Statistics, an estimated 130 Americans die every day from an opioid overdose ...
      Written By: Nouran Amin
      1
      JUN 12, 2019
      Cell & Molecular Biology
      Scientists Discover Why Arteries Harden & Find a Potential Treatment
      Scientists Discover Why Arteries Harden & Find a Potential Treatment
      As we get older, our arteries slowly begin to stiffen and then harden, which can lead to many serious complications. Now ...
      Written By: Carmen Leitch
      1
      JUN 11, 2019
      Health & Medicine
      Dietary Supplements are Severely Harmful for Young Adults
      Dietary Supplements are Severely Harmful for Young Adults
      Young people are a target market for dietary supplements for weight loss, muscle building, energy, and more. A team of r ...
      Written By: Tiffany Dazet
      1
      JUN 10, 2019
      Drug Discovery & Development
      Tart Cherry and Pain Management in Breast Cancer Patients
      Tart Cherry and Pain Management in Breast Cancer Patients
      In patients with non-metastatic breast cancer, treated with aromatase inhibitors, tart cherry was found to reduce the mu ...
      Written By: Nouran Amin
      1
      JUN 10, 2019
      Drug Discovery & Development
      Novel Treatments for Auto-immune Disorders
      Novel Treatments for Auto-immune Disorders
      A recent research study examined a library of almost 300,000 small molecules to search for a molecule that may be a pote ...
      Written By: Nouran Amin
      1
      JUN 10, 2019
      Cancer
      New discovery sheds light for precision medicine in cancer
      New discovery sheds light for precision medicine in cancer
      A recent study published in Cancer Research highlights findings of a molecular indicator that could provide a new way fo ...
      Written By: Kathryn DeMuth Sullivan
      2
      JUN 07, 2019
      Genetics & Genomics
      Genes for a Common Enzyme Family Found in an Unusual Place
      Genes for a Common Enzyme Family Found in an Unusual Place
      Researchers have discovered viruses with massive genomes, which contain surprising genes.
      Written By: Carmen Leitch
      1
      JUN 06, 2019
      Drug Discovery & Development
      Anti-Hypertensive Drug Use and Dementia?
      Anti-Hypertensive Drug Use and Dementia?
      A soon to be published study investigated the relationship between antihypertensive drug use and dementia in older adult ...
      Written By: Nouran Amin
      1
    JUN 19, 2019
    Drug Discovery & Development
    Experimental Drug Encourages Bone Growth in Children with Dwarfism
    Experimental Drug Encourages Bone Growth in Children with Dwarfism
    An experimental drug called vosoritide, alters certain proteins that block bone growth, which allowed the average annual ...
    Written By: Nouran Amin
    1
    JUN 19, 2019
    Drug Discovery & Development
    Antidepressants May Impair Empathy
    Antidepressants May Impair Empathy
    Depression is tagged with strong impairments of social functioning. Until recently, researchers believed that acute depr ...
    Written By: Nouran Amin
    1
    JUN 18, 2019
    Drug Discovery & Development
    Drug Compound May Treat Common Genetic Kidney Disease
    Drug Compound May Treat Common Genetic Kidney Disease
    Researchers from the University of Sheffield in collaboration with Glasgow-based biotech company Mironid, have developed ...
    Written By: Nouran Amin
    2
    JUN 18, 2019
    Health & Medicine
    Scientists Identify Which Gut Bacteria Interfere With Parkinson's Treatment
    Scientists Identify Which Gut Bacteria Interfere With Parkinson's Treatment
    A new study from a team of Harvard scientists discovered one of the first distinct examples of how gut bacteria can inte ...
    Written By: Tiffany Dazet
    1
    JUN 17, 2019
    Cell & Molecular Biology
    Researchers Discover Molecule That May Cause Lyme Disease Symptoms
    Researchers Discover Molecule That May Cause Lyme Disease Symptoms
    Scientists at Virginia Tech have found a molecule that can potentially improve the diagnosis and treatment of Lyme disea ...
    Written By: Carmen Leitch
    3
     
     
  • JUN 17, 2019
    Drug Discovery & Development
    Promising Hypertension Drug for Alzheimer Disease
    Promising Hypertension Drug for Alzheimer Disease
    In a study led by the American Heart Association, the blood pressure drug nilvadipine (a calcium channel blocker) was fo ...
    Written By: Nouran Amin
    2
    JUN 17, 2019
    Drug Discovery & Development
    Drug Delays Type 1 Diabetes in High Risk Individuals
    Drug Delays Type 1 Diabetes in High Risk Individuals
    An immunotherapeutic, involving anti-CD3 monoclonal antibody (teplizumab), was seen to slow down the progression to clin ...
    Written By: Nouran Amin
    1
    JUN 17, 2019
    Drug Discovery & Development
    Breakthrough Synthesis Advances Potent Anti-Cancer Agent
    Breakthrough Synthesis Advances Potent Anti-Cancer Agent
    What is now known as a "landmark in drug discovery", Harvard chemists have succeeded in synthesizing halichond ...
    Written By: Nouran Amin
    1
    JUN 16, 2019
    Health & Medicine
    Remember Joe Camel? E-cigarette cartoon ads increase the chances of vaping
    Remember Joe Camel? E-cigarette cartoon ads increase the chances of vaping
    Do you remember the infamous "Joe Camel" advertisements for cigarettes back in the 1980s and 90s? These ads su ...
    Written By: Dr. Nina Lichtenberg
    1
    JUN 16, 2019
    Microbiology
    Vulnerability in Famously Hard-to-Target Viruses is Identified
    Vulnerability in Famously Hard-to-Target Viruses is Identified
    The cold virus is famously difficult to target with drugs because it can mutate rapidly.
    Written By: Carmen Leitch
    1
     
     
  • JUN 15, 2019
    Cell & Molecular Biology
    Understanding and Treating the Mechanisms That Drive Rheumatoid Arthritis
    Understanding and Treating the Mechanisms That Drive Rheumatoid Arthritis
    In RA, cells of the immune system mistakenly attack the joints, and cause the painful inflammation that is a hallmark of ...
    Written By: Carmen Leitch
    1
    JUN 14, 2019
    Drug Discovery & Development
    Attaching a removable lock to an arthritis drug
    Attaching a removable lock to an arthritis drug
    A study published in PLOS Biology suggests that attaching a removable lock to an arthritis drug can increase its effecti ...
    Written By: Nouran Amin
    1
    JUN 13, 2019
    Health & Medicine
    Formation of Habitual Cannabis Use Drives Addiction
    Formation of Habitual Cannabis Use Drives Addiction
    According to a new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier, shift ...
    Written By: C Reardon
    1
    JUN 13, 2019
    Health & Medicine
    Can CBD Be Used to Treat Anxiety?
    Can CBD Be Used to Treat Anxiety?
    A 2019 study published on the National Center for Biotechnology Information showed that Cannabidiol might benefit a ...
    Written By: C Reardon
    1 1
    JUN 13, 2019
    Cancer
    This Molecule Compound Reduces Chemo Resistance
    This Molecule Compound Reduces Chemo Resistance
    Drug resistance is a major hindrance to cancer treatment. Researchers from Duke University, MIT and the University of Rh ...
    Written By: Julia Travers
    1
     
     
  • JUN 12, 2019
    Drug Discovery & Development
    Injectable Hydrogel Recruits Chemotherapeutics to Tumor Site
    Injectable Hydrogel Recruits Chemotherapeutics to Tumor Site
    Targeting tumor cells while avoiding harming healthy tissue remains a growing central challenge in the field of chemothe ...
    Written By: Nouran Amin
    1
    JUN 12, 2019
    Drug Discovery & Development
    Sustainable Production of Opiate Antidotes
    Sustainable Production of Opiate Antidotes
    According to the National Center for Health Statistics, an estimated 130 Americans die every day from an opioid overdose ...
    Written By: Nouran Amin
    1
    JUN 12, 2019
    Cell & Molecular Biology
    Scientists Discover Why Arteries Harden & Find a Potential Treatment
    Scientists Discover Why Arteries Harden & Find a Potential Treatment
    As we get older, our arteries slowly begin to stiffen and then harden, which can lead to many serious complications. Now ...
    Written By: Carmen Leitch
    1
    JUN 11, 2019
    Health & Medicine
    Dietary Supplements are Severely Harmful for Young Adults
    Dietary Supplements are Severely Harmful for Young Adults
    Young people are a target market for dietary supplements for weight loss, muscle building, energy, and more. A team of r ...
    Written By: Tiffany Dazet
    1
    JUN 10, 2019
    Drug Discovery & Development
    Tart Cherry and Pain Management in Breast Cancer Patients
    Tart Cherry and Pain Management in Breast Cancer Patients
    In patients with non-metastatic breast cancer, treated with aromatase inhibitors, tart cherry was found to reduce the mu ...
    Written By: Nouran Amin
    1
     
     
  • JUN 10, 2019
    Drug Discovery & Development
    Novel Treatments for Auto-immune Disorders
    Novel Treatments for Auto-immune Disorders
    A recent research study examined a library of almost 300,000 small molecules to search for a molecule that may be a pote ...
    Written By: Nouran Amin
    1
    JUN 10, 2019
    Cancer
    New discovery sheds light for precision medicine in cancer
    New discovery sheds light for precision medicine in cancer
    A recent study published in Cancer Research highlights findings of a molecular indicator that could provide a new way fo ...
    Written By: Kathryn DeMuth Sullivan
    2
    JUN 07, 2019
    Genetics & Genomics
    Genes for a Common Enzyme Family Found in an Unusual Place
    Genes for a Common Enzyme Family Found in an Unusual Place
    Researchers have discovered viruses with massive genomes, which contain surprising genes.
    Written By: Carmen Leitch
    1
    JUN 06, 2019
    Drug Discovery & Development
    Anti-Hypertensive Drug Use and Dementia?
    Anti-Hypertensive Drug Use and Dementia?
    A soon to be published study investigated the relationship between antihypertensive drug use and dementia in older adult ...
    Written By: Nouran Amin
    1
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