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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • MAY 22, 2018
      Drug Discovery & Development
      An Antibody Proven Effective in Treating Severe Asthma
      An Antibody Proven Effective in Treating Severe Asthma
      Severe asthma is a subtype of asthma where treatments usually do not have any effect on the individual. https://www.yout ...
      Written By: Nouran Amin
      2
      MAY 21, 2018
      Genetics & Genomics
      Using CRISPR for High-throughout Genetic Assessment
      Using CRISPR for High-throughout Genetic Assessment
      Researchers can now move beyond the painstaking manipulation of individual genes.
      Written By: Carmen Leitch
      2
      MAY 21, 2018
      Microbiology
      Common Antibacterial Chemical may Help Fight Lung Infections
      Common Antibacterial Chemical may Help Fight Lung Infections
      New research has found when triclosan is used with another FDA-approved drug, it can help fight deadly illness.
      Written By: Carmen Leitch
      2
      MAY 20, 2018
      Genetics & Genomics
      Gene Found to Help Prevent Brain Disease
      Gene Found to Help Prevent Brain Disease
      Researchers are learning more about the mechanisms that underlie aberrant protein buildup in neurodegeneration.
      Written By: Carmen Leitch
      2
      MAY 20, 2018
      Cell & Molecular Biology
      RNA-interfering Vaccine can Protect Plants From Pests
      RNA-interfering Vaccine can Protect Plants From Pests
      We need good solutions to pest management in agriculture to feed a growing population as the environment changes.
      Written By: Carmen Leitch
      2
      MAY 18, 2018
      Videos
      Seeing Inside of a Living Cell
      Seeing Inside of a Living Cell
      The Allen Institute for Cell Science created a powerful tool for visualizing the human cell, called the Allen Integrated ...
      Written By: Carmen Leitch
      2
      MAY 18, 2018
      Cell & Molecular Biology
      Likely Cause of Polycystic Ovarian Syndrome ID'ed
      Likely Cause of Polycystic Ovarian Syndrome ID'ed
      Polycystic ovary syndrome is a leading cause of infertility in women and can be a cause of miscarriage. Now research has ...
      Written By: Carmen Leitch
      2
      MAY 15, 2018
      Drug Discovery & Development
      Targeting Protein Kinases for Anti-Cancer Drug Development
      Targeting Protein Kinases for Anti-Cancer Drug Development
      A protein kinase, an enzyme, might be the key to developing new cancer drugs according to a research study at the Univer ...
      Written By: Nouran Amin
      2
      MAY 15, 2018
      Drug Discovery & Development
      Rett Syndrome: Possible Drug Treatment
      Rett Syndrome: Possible Drug Treatment
      A research study published in Cell Reports explains that a new drug was seen to reduce symptoms of Rett Syndrome in prec ...
      Written By: Nouran Amin
      2
      MAY 15, 2018
      Drug Discovery & Development
      A Cure for The Common Cold?
      A Cure for The Common Cold?
      Treating the common cold has never been simple and finding effective options has baffled scientists for centuries. The c ...
      Written By: Nouran Amin
      2
      MAY 14, 2018
      Drug Discovery & Development
      Gilenya: First Treatment for Pediatric MS
      Gilenya: First Treatment for Pediatric MS
         A drug known as Gilenya (fingolimod), which was first approved in 2010 for the treatment of Multiple Sclero ...
      Written By: Nouran Amin
      2
      MAY 14, 2018
      Immunology
      The Immune System's Antibodies Target Multiple Microbes
      The Immune System's Antibodies Target Multiple Microbes
      For the first time, scientists found that antibodies produced by the immune system can target multiple microbes, as oppo ...
      Written By: Kara Marker
      2
      MAY 09, 2018
      Cell & Molecular Biology
      Valuable insights into better protein expression
      Valuable insights into better protein expression
      Pharmaceutical companies, biotech, and academia all have a hand in accelerating our understanding of proteins, whether t ...
      Written By: Jennifer Ellis
      3
      MAY 08, 2018
      Drug Discovery & Development
      Developing a Drug For Genetic Obesity
      Developing a Drug For Genetic Obesity
      Researchers from the Institute for Experimental Pediatric Endocrinology of the Charité -- Universitätsmedizi ...
      Written By: Nouran Amin
      2
      MAY 08, 2018
      Drug Discovery & Development
      No More Hair Loss? Osteoporosis Drug Treats Baldness
      No More Hair Loss? Osteoporosis Drug Treats Baldness
          According to The University of Manchester's Centre for Dermatology Research, a recent developed drug c ...
      Written By: Nouran Amin
      2
      MAY 08, 2018
      Drug Discovery & Development
      Pure Form of An Illegal Euphoric Drug Treats PTSD
      Pure Form of An Illegal Euphoric Drug Treats PTSD
        Post-traumatic stress disorder (PTSD) is a psychiatric disorder where an individual has a difficult time recoveri ...
      Written By: Nouran Amin
      3
      MAY 08, 2018
      Drug Discovery & Development
      Promising Treatment for Alcoholism
      Promising Treatment for Alcoholism
      Investigators at the University of Texas at Austin have successfully used animal models to examine a drug believed to in ...
      Written By: Nouran Amin
      3
      MAY 08, 2018
      Genetics & Genomics
      A Genetic Assessment of a Drug-resistant Pathogen
      A Genetic Assessment of a Drug-resistant Pathogen
      Drug resistance is a growing threat to public health and is responsible for the death of around 23,000 people every year ...
      Written By: Carmen Leitch
      2
      MAY 07, 2018
      Microbiology
      West Nile Virus May Now Have a Treatment
      West Nile Virus May Now Have a Treatment
      West Nile Virus is a mosquito-borne disease with no effective treatments and no vaccine. That may be changing.
      Written By: Carmen Leitch
      2
      MAY 03, 2018
      Drug Discovery & Development
      Treating Migraines with Less Side-Effects
      Treating Migraines with Less Side-Effects
      According to a 2013 Global Burden of Disease Study and the World Health Organization (WHO), migraine makes the list as t ...
      Written By: Nouran Amin
      2
      MAY 03, 2018
      Drug Discovery & Development
      Re-Designing Treatments for Alzheimer Disease
      Re-Designing Treatments for Alzheimer Disease
      The most common form of dementia is Alzheimer which is a general term for memory loss and other cognitive abilities that ...
      Written By: Nouran Amin
      2
      MAY 03, 2018
      Drug Discovery & Development
      Developing Drugs to Combat Antibiotic Resistance
      Developing Drugs to Combat Antibiotic Resistance
      In accordance with the World Health Organization (WHO), antibiotic-resistant pathogens may soon become a public health c ...
      Written By: Nouran Amin
      3
      MAY 02, 2018
      Drug Discovery & Development
      New Kind of Sedative for Violent Patients
      New Kind of Sedative for Violent Patients
      A new drug developed in Australia by Queensland Ambulance Service (QAS) can effectively calm down violent patients. The ...
      Written By: Nouran Amin
      2
      APR 30, 2018
      Cell & Molecular Biology
      A New Mechanism of Drug Resistance is Revealed
      A New Mechanism of Drug Resistance is Revealed
      One way to combat the rise of antibiotic resistance is to find out how bacteria evade the effects of current drugs, to i ...
      Written By: Carmen Leitch
      2
    MAY 22, 2018
    Drug Discovery & Development
    An Antibody Proven Effective in Treating Severe Asthma
    An Antibody Proven Effective in Treating Severe Asthma
    Severe asthma is a subtype of asthma where treatments usually do not have any effect on the individual. https://www.yout ...
    Written By: Nouran Amin
    2
    MAY 21, 2018
    Genetics & Genomics
    Using CRISPR for High-throughout Genetic Assessment
    Using CRISPR for High-throughout Genetic Assessment
    Researchers can now move beyond the painstaking manipulation of individual genes.
    Written By: Carmen Leitch
    2
    MAY 21, 2018
    Microbiology
    Common Antibacterial Chemical may Help Fight Lung Infections
    Common Antibacterial Chemical may Help Fight Lung Infections
    New research has found when triclosan is used with another FDA-approved drug, it can help fight deadly illness.
    Written By: Carmen Leitch
    2
    MAY 20, 2018
    Genetics & Genomics
    Gene Found to Help Prevent Brain Disease
    Gene Found to Help Prevent Brain Disease
    Researchers are learning more about the mechanisms that underlie aberrant protein buildup in neurodegeneration.
    Written By: Carmen Leitch
    2
    MAY 20, 2018
    Cell & Molecular Biology
    RNA-interfering Vaccine can Protect Plants From Pests
    RNA-interfering Vaccine can Protect Plants From Pests
    We need good solutions to pest management in agriculture to feed a growing population as the environment changes.
    Written By: Carmen Leitch
    2
     
     
  • MAY 18, 2018
    Videos
    Seeing Inside of a Living Cell
    Seeing Inside of a Living Cell
    The Allen Institute for Cell Science created a powerful tool for visualizing the human cell, called the Allen Integrated ...
    Written By: Carmen Leitch
    2
    MAY 18, 2018
    Cell & Molecular Biology
    Likely Cause of Polycystic Ovarian Syndrome ID'ed
    Likely Cause of Polycystic Ovarian Syndrome ID'ed
    Polycystic ovary syndrome is a leading cause of infertility in women and can be a cause of miscarriage. Now research has ...
    Written By: Carmen Leitch
    2
    MAY 15, 2018
    Drug Discovery & Development
    Targeting Protein Kinases for Anti-Cancer Drug Development
    Targeting Protein Kinases for Anti-Cancer Drug Development
    A protein kinase, an enzyme, might be the key to developing new cancer drugs according to a research study at the Univer ...
    Written By: Nouran Amin
    2
    MAY 15, 2018
    Drug Discovery & Development
    Rett Syndrome: Possible Drug Treatment
    Rett Syndrome: Possible Drug Treatment
    A research study published in Cell Reports explains that a new drug was seen to reduce symptoms of Rett Syndrome in prec ...
    Written By: Nouran Amin
    2
    MAY 15, 2018
    Drug Discovery & Development
    A Cure for The Common Cold?
    A Cure for The Common Cold?
    Treating the common cold has never been simple and finding effective options has baffled scientists for centuries. The c ...
    Written By: Nouran Amin
    2
     
     
  • MAY 14, 2018
    Drug Discovery & Development
    Gilenya: First Treatment for Pediatric MS
    Gilenya: First Treatment for Pediatric MS
       A drug known as Gilenya (fingolimod), which was first approved in 2010 for the treatment of Multiple Sclero ...
    Written By: Nouran Amin
    2
    MAY 14, 2018
    Immunology
    The Immune System's Antibodies Target Multiple Microbes
    The Immune System's Antibodies Target Multiple Microbes
    For the first time, scientists found that antibodies produced by the immune system can target multiple microbes, as oppo ...
    Written By: Kara Marker
    2
    MAY 09, 2018
    Cell & Molecular Biology
    Valuable insights into better protein expression
    Valuable insights into better protein expression
    Pharmaceutical companies, biotech, and academia all have a hand in accelerating our understanding of proteins, whether t ...
    Written By: Jennifer Ellis
    3
    MAY 08, 2018
    Drug Discovery & Development
    Developing a Drug For Genetic Obesity
    Developing a Drug For Genetic Obesity
    Researchers from the Institute for Experimental Pediatric Endocrinology of the Charité -- Universitätsmedizi ...
    Written By: Nouran Amin
    2
    MAY 08, 2018
    Drug Discovery & Development
    No More Hair Loss? Osteoporosis Drug Treats Baldness
    No More Hair Loss? Osteoporosis Drug Treats Baldness
        According to The University of Manchester's Centre for Dermatology Research, a recent developed drug c ...
    Written By: Nouran Amin
    2
     
     
  • MAY 08, 2018
    Drug Discovery & Development
    Pure Form of An Illegal Euphoric Drug Treats PTSD
    Pure Form of An Illegal Euphoric Drug Treats PTSD
      Post-traumatic stress disorder (PTSD) is a psychiatric disorder where an individual has a difficult time recoveri ...
    Written By: Nouran Amin
    3
    MAY 08, 2018
    Drug Discovery & Development
    Promising Treatment for Alcoholism
    Promising Treatment for Alcoholism
    Investigators at the University of Texas at Austin have successfully used animal models to examine a drug believed to in ...
    Written By: Nouran Amin
    3
    MAY 08, 2018
    Genetics & Genomics
    A Genetic Assessment of a Drug-resistant Pathogen
    A Genetic Assessment of a Drug-resistant Pathogen
    Drug resistance is a growing threat to public health and is responsible for the death of around 23,000 people every year ...
    Written By: Carmen Leitch
    2
    MAY 07, 2018
    Microbiology
    West Nile Virus May Now Have a Treatment
    West Nile Virus May Now Have a Treatment
    West Nile Virus is a mosquito-borne disease with no effective treatments and no vaccine. That may be changing.
    Written By: Carmen Leitch
    2
    MAY 03, 2018
    Drug Discovery & Development
    Treating Migraines with Less Side-Effects
    Treating Migraines with Less Side-Effects
    According to a 2013 Global Burden of Disease Study and the World Health Organization (WHO), migraine makes the list as t ...
    Written By: Nouran Amin
    2
     
     
  • MAY 03, 2018
    Drug Discovery & Development
    Re-Designing Treatments for Alzheimer Disease
    Re-Designing Treatments for Alzheimer Disease
    The most common form of dementia is Alzheimer which is a general term for memory loss and other cognitive abilities that ...
    Written By: Nouran Amin
    2
    MAY 03, 2018
    Drug Discovery & Development
    Developing Drugs to Combat Antibiotic Resistance
    Developing Drugs to Combat Antibiotic Resistance
    In accordance with the World Health Organization (WHO), antibiotic-resistant pathogens may soon become a public health c ...
    Written By: Nouran Amin
    3
    MAY 02, 2018
    Drug Discovery & Development
    New Kind of Sedative for Violent Patients
    New Kind of Sedative for Violent Patients
    A new drug developed in Australia by Queensland Ambulance Service (QAS) can effectively calm down violent patients. The ...
    Written By: Nouran Amin
    2
    APR 30, 2018
    Cell & Molecular Biology
    A New Mechanism of Drug Resistance is Revealed
    A New Mechanism of Drug Resistance is Revealed
    One way to combat the rise of antibiotic resistance is to find out how bacteria evade the effects of current drugs, to i ...
    Written By: Carmen Leitch
    2
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