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Drug Discovery
Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
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APR 29, 2018Genetics & Genomics
The CRISPR/Cas9 gene-editing tool was made from an immune defense system used by bacteria. Scientists have found it has ...Written By: Carmen LeitchAPR 24, 2018Drug Discovery & Development
The method of choice in drug-discovery in the past two decades has been target-based screening. Now, phenotypic screenin ...Written By: Nouran AminAPR 24, 2018Drug Discovery & Development
Investigators at University of Lincoln in the UK have developed a new technique using nanotechnology which may deliver d ...Written By: Nouran AminAPR 24, 2018Drug Discovery & Development
A new therapy known as ‘prostate artery embolization’ or PAE seeks to treat the non-cancerous enlargement of ...Written By: Nouran AminAPR 24, 2018Drug Discovery & Development
Asthma is a chronic respiratory disease. It is common and affects more than 300 million people worldwide and over 40 mil ...Written By: Nouran AminAPR 20, 2018Immunology
Memory T cells: where do they come from and how is their production controlled? Researchers from the Scripps Research In ...Written By: Kara MarkerAPR 17, 2018Cardiology
Scientists from Brazil have confirmed that listening to music in the hour following the administration of drugs designed ...Written By: Kara MarkerAPR 17, 2018Neuroscience
Who doesn't love a nice big dish of hot beets for supper? Delicious, right? OK, they may not be the darling of the v ...Written By: Brenda Kelley KimAPR 16, 2018Cell & Molecular Biology
Sepsis happens when the response to an infection gets out of control; body-wide inflammation occurs, which can be fatal.Written By: Carmen LeitchAPR 15, 2018Drug Discovery & Development
A new drug by the name of ‘ravidasvir’ is part of a hepatitis c combination treatment that may be an afforda ...Written By: Nouran AminAPR 15, 2018Drug Discovery & Development
A study published in Nature Medicine examines a monoclonal antibody isolated from the blood of individuals vaccinated fo ...Written By: Nouran AminAPR 14, 2018Drug Discovery & Development
A drug-free treatment known as Freespira® was developed by a digitalized therapeutic company, Palo Alto Health Scien ...Written By: Nouran AminAPR 14, 2018Drug Discovery & Development
Acute myeloid leukemia (AML) is a lethal cancer of the blood and bone marrow. It affects a group of white blood c ...Written By: Nouran AminAPR 11, 2018Chemistry & Physics
Mass spectrometry (MS) is a sensitive and versatile analytical technique that can detect, identify and quantify test mol ...Written By: Daniel DuanAPR 10, 2018Drug Discovery & Development
Investigators have unveiled a new class of drug that may treat cancer patients who can no longer respond to approved the ...Written By: Nouran AminAPR 10, 2018Drug Discovery & Development
Uterine serous carcinoma is rare occurring in less than 10 percent of all cancer types of the endometrium. However, this ...Written By: Nouran AminAPR 10, 2018Drug Discovery & Development
Chronic lymphocytic leukemia (CLL) is a form of cancer that that first occurs in the cells that become certain white blo ...Written By: Nouran AminAPR 10, 2018Clinical & Molecular DX
Two anti-cancer drugs are better than one, and the discovery of a new biomarker will likely help researchers identify th ...Written By: Kara MarkerAPR 09, 2018Drug Discovery & Development
Transthyretin amyloidosis (ATTR) is a slowly progressive disease characterized by the buildup of abnormal deposits of a ...Written By: Nouran AminAPR 08, 2018Microbiology
This new kind of compound acts in a unique way, and may be effective against drug-resistant bacteria.Written By: Carmen LeitchAPR 06, 2018Health & Medicine
The birth control pill was a boon to women when it was introduced because it meant that family planning could be handled ...Written By: Brenda Kelley KimAPR 03, 2018Drug Discovery & Development
According to the National Cancer Institute, lung cancer is the most common cause of cancer death for both men and women ...Written By: Nouran AminAPR 02, 2018Drug Discovery & Development
DNA-encoded chemical library (DECL), containing about 35 million different drugs, is a new screening method devel ...Written By: Nouran AminAPR 02, 2018Drug Discovery & Development
Research published in The Lancet Oncology explains how the drug Larotrectinib can treat cancer cells that ...Written By: Nouran Amin
APR 29, 2018
Genetics & Genomics
The CRISPR/Cas9 gene-editing tool was made from an immune defense system used by bacteria. Scientists have found it has
...
Written By:
Carmen Leitch
APR 24, 2018
Drug Discovery & Development
The method of choice in drug-discovery in the past two decades has been target-based screening. Now, phenotypic screenin
...
Written By:
Nouran Amin
APR 24, 2018
Drug Discovery & Development
Investigators at University of Lincoln in the UK have developed a new technique using nanotechnology which may deliver d
...
Written By:
Nouran Amin
APR 24, 2018
Drug Discovery & Development
A new therapy known as ‘prostate artery embolization’ or PAE seeks to treat the non-cancerous enlargement of
...
Written By:
Nouran Amin
APR 24, 2018
Drug Discovery & Development
Asthma is a chronic respiratory disease. It is common and affects more than 300 million people worldwide and over 40 mil
...
Written By:
Nouran Amin
APR 20, 2018
Immunology
Memory T cells: where do they come from and how is their production controlled? Researchers from the Scripps Research In
...
Written By:
Kara Marker
APR 17, 2018
Cardiology
Scientists from Brazil have confirmed that listening to music in the hour following the administration of drugs designed
...
Written By:
Kara Marker
APR 17, 2018
Neuroscience
Who doesn't love a nice big dish of hot beets for supper? Delicious, right? OK, they may not be the darling of the v
...
Written By:
Brenda Kelley Kim
APR 16, 2018
Cell & Molecular Biology
Sepsis happens when the response to an infection gets out of control; body-wide inflammation occurs, which can be fatal.
Written By:
Carmen Leitch
APR 15, 2018
Drug Discovery & Development
A new drug by the name of ‘ravidasvir’ is part of a hepatitis c combination treatment that may be an afforda
...
Written By:
Nouran Amin
APR 15, 2018
Drug Discovery & Development
A study published in Nature Medicine examines a monoclonal antibody isolated from the blood of individuals vaccinated fo
...
Written By:
Nouran Amin
APR 14, 2018
Drug Discovery & Development
A drug-free treatment known as Freespira® was developed by a digitalized therapeutic company, Palo Alto Health Scien
...
Written By:
Nouran Amin
APR 14, 2018
Drug Discovery & Development
Acute myeloid leukemia (AML) is a lethal cancer of the blood and bone marrow. It affects a group of white blood c
...
Written By:
Nouran Amin
APR 11, 2018
Chemistry & Physics
Mass spectrometry (MS) is a sensitive and versatile analytical technique that can detect, identify and quantify test mol
...
Written By:
Daniel Duan
APR 10, 2018
Drug Discovery & Development
Investigators have unveiled a new class of drug that may treat cancer patients who can no longer respond to approved the
...
Written By:
Nouran Amin
APR 10, 2018
Drug Discovery & Development
Uterine serous carcinoma is rare occurring in less than 10 percent of all cancer types of the endometrium. However, this
...
Written By:
Nouran Amin
APR 10, 2018
Drug Discovery & Development
Chronic lymphocytic leukemia (CLL) is a form of cancer that that first occurs in the cells that become certain white blo
...
Written By:
Nouran Amin
APR 10, 2018
Clinical & Molecular DX
Two anti-cancer drugs are better than one, and the discovery of a new biomarker will likely help researchers identify th
...
Written By:
Kara Marker
APR 09, 2018
Drug Discovery & Development
Transthyretin amyloidosis (ATTR) is a slowly progressive disease characterized by the buildup of abnormal deposits of a
...
Written By:
Nouran Amin
APR 08, 2018
Microbiology
This new kind of compound acts in a unique way, and may be effective against drug-resistant bacteria.
Written By:
Carmen Leitch
APR 06, 2018
Health & Medicine
The birth control pill was a boon to women when it was introduced because it meant that family planning could be handled
...
Written By:
Brenda Kelley Kim
APR 03, 2018
Drug Discovery & Development
According to the National Cancer Institute, lung cancer is the most common cause of cancer death for both men and women
...
Written By:
Nouran Amin
APR 02, 2018
Drug Discovery & Development
DNA-encoded chemical library (DECL), containing about 35 million different drugs, is a new screening method devel
...
Written By:
Nouran Amin
APR 02, 2018
Drug Discovery & Development
Research published in The Lancet Oncology explains how the drug Larotrectinib can treat cancer cells that
...
Written By:
Nouran Amin