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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • APR 01, 2018
      Drug Discovery & Development
      'BET Inhibitors' Block the Expression of Cancer-Causing Genes
      'BET Inhibitors' Block the Expression of Cancer-Causing Genes
      Investigators at Michigan State University in East Lansing are finding new ways to treat cancer. For one, they are inter ...
      Written By: Nouran Amin
      2
      MAR 31, 2018
      Cardiology
      Dietary Supplement Mimics Calorie Restriction, Improves Blood Pressure
      Dietary Supplement Mimics Calorie Restriction, Improves Blood Pressure
      Limiting the number of calories you eat is a simple way to stay healthy, but its implementation couldn’t be harder ...
      Written By: Kara Marker
      3
      MAR 25, 2018
      Drug Discovery & Development
      The Next Step Treatment for Hookworm Infections
      The Next Step Treatment for Hookworm Infections
      Researchers have discovered a crucial step in blood digestion of hookworms that feed and infect the blood of mice. The k ...
      Written By: Nouran Amin
      2
      MAR 25, 2018
      Drug Discovery & Development
      New Drug 'Siponimod' Seeks to Treat Secondary Progressive MS
      New Drug 'Siponimod' Seeks to Treat Secondary Progressive MS
      Multiple sclerosis (MS) is an autoimmune disease of the central nervous system where the affected individual’s imm ...
      Written By: Nouran Amin
      2
      MAR 25, 2018
      Drug Discovery & Development
      'Drug Re-purposing' Shows Promising Treatment for Mesothelioma
      'Drug Re-purposing' Shows Promising Treatment for Mesothelioma
      Mesothelioma is an aggressive and deadly form of cancer that occurs in the outer linings of the internal organs, particu ...
      Written By: Nouran Amin
      2
      MAR 24, 2018
      Drug Discovery & Development
      A Modified Version of Herpes Simplex Virus-1 May Cure Advanced-Stage Liver Tumors
      A Modified Version of Herpes Simplex Virus-1 May Cure Advanced-Stage Liver Tumors
      A recent study showcased in the Society of Interventional Radiology Annual Scientific Meeting explains that liver Tumors ...
      Written By: Nouran Amin
      2
      MAR 20, 2018
      Drug Discovery & Development
      The 'Molecular Key' in Developing Tuberculosis Drugs
      The 'Molecular Key' in Developing Tuberculosis Drugs
      Tuberculosis is an ancient disease, signs of it were examined in Egyptian mummies. It is caused by the bacterium and pat ...
      Written By: Nouran Amin
      3
      MAR 20, 2018
      Drug Discovery & Development
      Treatment for Post-Surgical Nausea and Vomiting
      Treatment for Post-Surgical Nausea and Vomiting
      Amisulpride, a drug developed for the treatment of schizophrenia, was studied to be effective in preventing postoperativ ...
      Written By: Nouran Amin
      1
      MAR 20, 2018
      Chemistry & Physics
      The History of Warfarin
      The History of Warfarin
      When Professor Karl-Paul Link of University of Wisconsin was helping ranchers to solve the mystery behind dying cattle b ...
      Written By: Daniel Duan
      1
      MAR 20, 2018
      Technology
      New Orleans Ends Secretive Crime Prediction Program
      New Orleans Ends Secretive Crime Prediction Program
      New Orleans Mayor Mitch Landrieu announced on March 14, 2018 that his office would be ending the data-crime prediction p ...
      Written By: Julia Travers
      2
      MAR 19, 2018
      Drug Discovery & Development
      Menopausal Hot Flashes: Potential Treatment
      Menopausal Hot Flashes: Potential Treatment
      Menopause defined as the time in a female’s life (usually from 45 to 55 years of age) where the monthly menstrual ...
      Written By: Nouran Amin
      2
      MAR 16, 2018
      Drug Discovery & Development
      The 'Triple Pill': A New Blood Pressure Treatment
      The 'Triple Pill': A New Blood Pressure Treatment
      Even though there exists an abundance of blood pressure-lowering drugs, high blood pressure persists to be a health conc ...
      Written By: Nouran Amin
      2
      MAR 15, 2018
      Health & Medicine
      Cannabis compound shows promise for severe epilepsy
      Cannabis compound shows promise for severe epilepsy
      For the first time, a form of medicinal cannabis has been shown to reduce—and even stop—seizures in some chi ...
      Written By: Invisiverse Puccio
      2
      MAR 15, 2018
      Cannabis Sciences
      Light controls variants of active ingredient in cannabis
      Light controls variants of active ingredient in cannabis
      Chemists have synthesized several variants of THC, the active ingredient in cannabis. The ability to alter its structure ...
      Written By: Invisiverse Puccio
      2
      MAR 12, 2018
      Microbiology
      Pond Virus Cures Patient's Antibiotic-resistant Infection
      Pond Virus Cures Patient's Antibiotic-resistant Infection
      Some viruses, called bacteriophages, can kill specific kinds of bacteria.
      Written By: Carmen Leitch
      2
      MAR 12, 2018
      Drug Discovery & Development
      Treating Hearing Loss: A Set of Inhibiting Drugs Provide Promising Results
      Treating Hearing Loss: A Set of Inhibiting Drugs Provide Promising Results
      Our inner ears contain roughly 30,000 tiny hair cells that work to detect sound waves as well as to translate these wave ...
      Written By: Nouran Amin
      3 1
      MAR 11, 2018
      Drug Discovery & Development
      New Drug for Multiple Sclerosis? Potential Therapeutic Treatment Uncovered
      New Drug for Multiple Sclerosis? Potential Therapeutic Treatment Uncovered
      Multiple sclerosis (MS) is a neurological disease that is unpredictable and often disabling in affected individuals. It ...
      Written By: Nouran Amin
      2
      MAR 11, 2018
      Drug Discovery & Development
      FDA approves 'Trogarzo' for HIV
      FDA approves 'Trogarzo' for HIV
      U.S. Food and Drug Administration approved a new treatment for patients living with multi-drug resistant HIV. The treatm ...
      Written By: Nouran Amin
      2
      MAR 10, 2018
      Drug Discovery & Development
      Treatment Intended for Osteoarthritis, Decreases Opioid Dependence
      Treatment Intended for Osteoarthritis, Decreases Opioid Dependence
      Treatment intended for osteoarthritis succeeds in decreasing symptoms of an opioid addiction.
      Written By: Nouran Amin
      2
      MAR 09, 2018
      Chemistry & Physics
      New Imaging Method Solves Molecular Structures in Motion
      New Imaging Method Solves Molecular Structures in Motion
      Researchers from The State University of New York at Buffalo (UB) announced they have developed an innovative imaging me ...
      Written By: Daniel Duan
      1
      MAR 08, 2018
      Immunology
      How does brain cancer escape the immune system?
      How does brain cancer escape the immune system?
      One of the most lethal forms of brain cancer owes most of its deadliness to its evasion of the immune system - a nasty t ...
      Written By: Kara Marker
      3
      MAR 06, 2018
      Drug Discovery & Development
      Potential Therapeutic Treatment for Bile Duct Cancer
      Potential Therapeutic Treatment for Bile Duct Cancer
      A therapeutic treatment consisting of Hsp90 inhibiting drugs have been successful at destroying bile duct cancer cells.
      Written By: Nouran Amin
      3
      MAR 05, 2018
      Drug Discovery & Development
      First Medication Claimed to Treat Symptoms of Autism Enters Clinical Trial
      First Medication Claimed to Treat Symptoms of Autism Enters Clinical Trial
      A recently developed drug may be the first medication to treat symptoms of autism and increase the ability of autistic i ...
      Written By: Nouran Amin
      2
      MAR 03, 2018
      Drug Discovery & Development
      Doubting the Wonder Drug
      Doubting the Wonder Drug
      Baclofen a drug recently used to treat alcohol use disorders. It has been re-examined at the University of Liverpool to ...
      Written By: Nouran Amin
      1
    APR 01, 2018
    Drug Discovery & Development
    'BET Inhibitors' Block the Expression of Cancer-Causing Genes
    'BET Inhibitors' Block the Expression of Cancer-Causing Genes
    Investigators at Michigan State University in East Lansing are finding new ways to treat cancer. For one, they are inter ...
    Written By: Nouran Amin
    2
    MAR 31, 2018
    Cardiology
    Dietary Supplement Mimics Calorie Restriction, Improves Blood Pressure
    Dietary Supplement Mimics Calorie Restriction, Improves Blood Pressure
    Limiting the number of calories you eat is a simple way to stay healthy, but its implementation couldn’t be harder ...
    Written By: Kara Marker
    3
    MAR 25, 2018
    Drug Discovery & Development
    The Next Step Treatment for Hookworm Infections
    The Next Step Treatment for Hookworm Infections
    Researchers have discovered a crucial step in blood digestion of hookworms that feed and infect the blood of mice. The k ...
    Written By: Nouran Amin
    2
    MAR 25, 2018
    Drug Discovery & Development
    New Drug 'Siponimod' Seeks to Treat Secondary Progressive MS
    New Drug 'Siponimod' Seeks to Treat Secondary Progressive MS
    Multiple sclerosis (MS) is an autoimmune disease of the central nervous system where the affected individual’s imm ...
    Written By: Nouran Amin
    2
    MAR 25, 2018
    Drug Discovery & Development
    'Drug Re-purposing' Shows Promising Treatment for Mesothelioma
    'Drug Re-purposing' Shows Promising Treatment for Mesothelioma
    Mesothelioma is an aggressive and deadly form of cancer that occurs in the outer linings of the internal organs, particu ...
    Written By: Nouran Amin
    2
     
     
  • MAR 24, 2018
    Drug Discovery & Development
    A Modified Version of Herpes Simplex Virus-1 May Cure Advanced-Stage Liver Tumors
    A Modified Version of Herpes Simplex Virus-1 May Cure Advanced-Stage Liver Tumors
    A recent study showcased in the Society of Interventional Radiology Annual Scientific Meeting explains that liver Tumors ...
    Written By: Nouran Amin
    2
    MAR 20, 2018
    Drug Discovery & Development
    The 'Molecular Key' in Developing Tuberculosis Drugs
    The 'Molecular Key' in Developing Tuberculosis Drugs
    Tuberculosis is an ancient disease, signs of it were examined in Egyptian mummies. It is caused by the bacterium and pat ...
    Written By: Nouran Amin
    3
    MAR 20, 2018
    Drug Discovery & Development
    Treatment for Post-Surgical Nausea and Vomiting
    Treatment for Post-Surgical Nausea and Vomiting
    Amisulpride, a drug developed for the treatment of schizophrenia, was studied to be effective in preventing postoperativ ...
    Written By: Nouran Amin
    1
    MAR 20, 2018
    Chemistry & Physics
    The History of Warfarin
    The History of Warfarin
    When Professor Karl-Paul Link of University of Wisconsin was helping ranchers to solve the mystery behind dying cattle b ...
    Written By: Daniel Duan
    1
    MAR 20, 2018
    Technology
    New Orleans Ends Secretive Crime Prediction Program
    New Orleans Ends Secretive Crime Prediction Program
    New Orleans Mayor Mitch Landrieu announced on March 14, 2018 that his office would be ending the data-crime prediction p ...
    Written By: Julia Travers
    2
     
     
  • MAR 19, 2018
    Drug Discovery & Development
    Menopausal Hot Flashes: Potential Treatment
    Menopausal Hot Flashes: Potential Treatment
    Menopause defined as the time in a female’s life (usually from 45 to 55 years of age) where the monthly menstrual ...
    Written By: Nouran Amin
    2
    MAR 16, 2018
    Drug Discovery & Development
    The 'Triple Pill': A New Blood Pressure Treatment
    The 'Triple Pill': A New Blood Pressure Treatment
    Even though there exists an abundance of blood pressure-lowering drugs, high blood pressure persists to be a health conc ...
    Written By: Nouran Amin
    2
    MAR 15, 2018
    Health & Medicine
    Cannabis compound shows promise for severe epilepsy
    Cannabis compound shows promise for severe epilepsy
    For the first time, a form of medicinal cannabis has been shown to reduce—and even stop—seizures in some chi ...
    Written By: Invisiverse Puccio
    2
    MAR 15, 2018
    Cannabis Sciences
    Light controls variants of active ingredient in cannabis
    Light controls variants of active ingredient in cannabis
    Chemists have synthesized several variants of THC, the active ingredient in cannabis. The ability to alter its structure ...
    Written By: Invisiverse Puccio
    2
    MAR 12, 2018
    Microbiology
    Pond Virus Cures Patient's Antibiotic-resistant Infection
    Pond Virus Cures Patient's Antibiotic-resistant Infection
    Some viruses, called bacteriophages, can kill specific kinds of bacteria.
    Written By: Carmen Leitch
    2
     
     
  • MAR 12, 2018
    Drug Discovery & Development
    Treating Hearing Loss: A Set of Inhibiting Drugs Provide Promising Results
    Treating Hearing Loss: A Set of Inhibiting Drugs Provide Promising Results
    Our inner ears contain roughly 30,000 tiny hair cells that work to detect sound waves as well as to translate these wave ...
    Written By: Nouran Amin
    3 1
    MAR 11, 2018
    Drug Discovery & Development
    New Drug for Multiple Sclerosis? Potential Therapeutic Treatment Uncovered
    New Drug for Multiple Sclerosis? Potential Therapeutic Treatment Uncovered
    Multiple sclerosis (MS) is a neurological disease that is unpredictable and often disabling in affected individuals. It ...
    Written By: Nouran Amin
    2
    MAR 11, 2018
    Drug Discovery & Development
    FDA approves 'Trogarzo' for HIV
    FDA approves 'Trogarzo' for HIV
    U.S. Food and Drug Administration approved a new treatment for patients living with multi-drug resistant HIV. The treatm ...
    Written By: Nouran Amin
    2
    MAR 10, 2018
    Drug Discovery & Development
    Treatment Intended for Osteoarthritis, Decreases Opioid Dependence
    Treatment Intended for Osteoarthritis, Decreases Opioid Dependence
    Treatment intended for osteoarthritis succeeds in decreasing symptoms of an opioid addiction.
    Written By: Nouran Amin
    2
    MAR 09, 2018
    Chemistry & Physics
    New Imaging Method Solves Molecular Structures in Motion
    New Imaging Method Solves Molecular Structures in Motion
    Researchers from The State University of New York at Buffalo (UB) announced they have developed an innovative imaging me ...
    Written By: Daniel Duan
    1
     
     
  • MAR 08, 2018
    Immunology
    How does brain cancer escape the immune system?
    How does brain cancer escape the immune system?
    One of the most lethal forms of brain cancer owes most of its deadliness to its evasion of the immune system - a nasty t ...
    Written By: Kara Marker
    3
    MAR 06, 2018
    Drug Discovery & Development
    Potential Therapeutic Treatment for Bile Duct Cancer
    Potential Therapeutic Treatment for Bile Duct Cancer
    A therapeutic treatment consisting of Hsp90 inhibiting drugs have been successful at destroying bile duct cancer cells.
    Written By: Nouran Amin
    3
    MAR 05, 2018
    Drug Discovery & Development
    First Medication Claimed to Treat Symptoms of Autism Enters Clinical Trial
    First Medication Claimed to Treat Symptoms of Autism Enters Clinical Trial
    A recently developed drug may be the first medication to treat symptoms of autism and increase the ability of autistic i ...
    Written By: Nouran Amin
    2
    MAR 03, 2018
    Drug Discovery & Development
    Doubting the Wonder Drug
    Doubting the Wonder Drug
    Baclofen a drug recently used to treat alcohol use disorders. It has been re-examined at the University of Liverpool to ...
    Written By: Nouran Amin
    1
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