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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • MAR 01, 2018
      Drug Discovery & Development
      The 24 hour Flu-Killing Drug
      The 24 hour Flu-Killing Drug
      A pharmaceutical company, Shinogi, in Japan has developed an experimental drug that may kill the flu virus in as little ...
      Written By: Nouran Amin
      2
      FEB 28, 2018
      Immunology
      New Digital Imaging Analysis Spots HIV Degradation
      New Digital Imaging Analysis Spots HIV Degradation
      A new system that tracks proteins as they come and go in the cell is predicted to help scientists identify therapeutic t ...
      Written By: Kara Marker
      2
      FEB 27, 2018
      Cell & Molecular Biology
      Venom Compound Eases Arthritis Symptoms
      Venom Compound Eases Arthritis Symptoms
      Rheumatoid arthritis is an autoimmune disorder affecting around 1.3 million people. Those patients may eventually use a ...
      Written By: Carmen Leitch
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      FEB 26, 2018
      Microbiology
      Looking to Bacteria for the Next Antibiotic
      Looking to Bacteria for the Next Antibiotic
      Bacteria can be a surprising source of antibiotics. One example is Streptomyces chartreusis, which can secrete a variety ...
      Written By: Carmen Leitch
      1
      FEB 21, 2018
      Chemistry & Physics
      Smell of Death and the New Insights of Mood Disorders
      Smell of Death and the New Insights of Mood Disorders
      Eerie and distinctive, the smell of a dead body comes mainly from small molecules known as diamines, products of degrada ...
      Written By: Daniel Duan
      2
      FEB 20, 2018
      Microbiology
      Insulin has Gone Viral
      Insulin has Gone Viral
      Our bodies need insulin to control the amount of sugar we have in our blood. Diabetes happens when that process fails, a ...
      Written By: Carmen Leitch
      1
      FEB 14, 2018
      Neuroscience
      Can Brain Damage From Alcohol Be Reversed?
      Can Brain Damage From Alcohol Be Reversed?
      Heavy consumption of alcohol over an extended period can negatively affect the brain. Neurogenesis, the ability of the b ...
      Written By: Brenda Kelley Kim
      2
      FEB 08, 2018
      Health & Medicine
      A Drug for Early Stage MS is Approved in Europe and the UK
      A Drug for Early Stage MS is Approved in Europe and the UK
      Multiple sclerosis (MS) is the most prevalent neurological disability around the globe. While onset could be at any age, ...
      Written By: Brenda Kelley Kim
      2
      FEB 07, 2018
      Immunology
      NOD2 Pathway Linked to Crohn's Disease and Multiple Sclerosis
      NOD2 Pathway Linked to Crohn's Disease and Multiple Sclerosis
      Defects in the body at the molecular level could at least partially explain why inflammatory diseases like Crohn’s ...
      Written By: Kara Marker
      2
      JAN 31, 2018
      Cell & Molecular Biology
      Getting to the Details of how Antipsychotic Drugs Work
      Getting to the Details of how Antipsychotic Drugs Work
      Around 1.6 percent of adults take antipsychotic medication, according to one study, but their mode of efficacy is not we ...
      Written By: Carmen Leitch
      2
      JAN 27, 2018
      Genetics & Genomics
      A Botulinum Toxin Jumped to a new Species of Bacteria
      A Botulinum Toxin Jumped to a new Species of Bacteria
      Research shows how a bacterial pathogen that is resistant to antibiotics could potentially gain the ability to produce a ...
      Written By: Carmen Leitch
      2
      JAN 26, 2018
      Cardiology
      Heart Cells Sense Tension and Contraction in Heart Disease
      Heart Cells Sense Tension and Contraction in Heart Disease
      After a heart attack, heart cells lose sensitivity. According to recent discoveries from Queen Mary University of London ...
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      3
      JAN 19, 2018
      Genetics & Genomics
      Amazing Images Reveal a Fundamental Process of Life
      Amazing Images Reveal a Fundamental Process of Life
      For the first time, scientists have captred images of the process by which DNA is transcribed into RNA
      Written By: Carmen Leitch
      2
      JAN 18, 2018
      Drug Discovery & Development
      Treatment of a Childhood Cancer: An Overview
      Treatment of a Childhood Cancer: An Overview
      Brief overview of Ewing sarcoma therapeutics
      Written By: Courtney Schaal
      2
      JAN 18, 2018
      Health & Medicine
      Cough Medicine, Opioids, and the FDA
      Cough Medicine, Opioids, and the FDA
      The opioid addiction epidemic is a serious health concern in the United States. Deaths from drug overdoses reached a hig ...
      Written By: Brenda Kelley Kim
      2
      JAN 14, 2018
      Drug Discovery & Development
      Treatment for Aging Hearts: Exercise.
      Treatment for Aging Hearts: Exercise.
      It is well known exercise can prevent heart-related health issues, but recently researcher show it can actually reverse ...
      Written By: Courtney Schaal
      2
      JAN 12, 2018
      Cardiology
      Creating Stem Cells to See Heart Disease Like Never Before
      Creating Stem Cells to See Heart Disease Like Never Before
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      JAN 10, 2018
      Immunology
      New Treatment on the Horizon for Marburg Virus
      New Treatment on the Horizon for Marburg Virus
      For the first time, scientists have been able to gather evidence for a new antibody-based drug to treat people infected ...
      Written By: Kara Marker
      5
      JAN 09, 2018
      Drug Discovery & Development
      To fight the opioid epidemic, take drug makers to court?
      To fight the opioid epidemic, take drug makers to court?
      Litigation against drug manufacturers that produce and distribute opioids could be a promising option in the fight again ...
      Written By: The Scripps Research Institute (TSRI)
      3
      JAN 09, 2018
      Drug Discovery & Development
      Viruses could inspire nano drug-delivery device
      Viruses could inspire nano drug-delivery device
      Researchers have discovered a path toward virus-like, nanoscale devices that may be able to deliver drugs to cells by ch ...
      Written By: The Scripps Research Institute (TSRI)
      3
      JAN 08, 2018
      Cell & Molecular Biology
      Treatment Strategies for Multidrug-resistant Chronic Infections
      Treatment Strategies for Multidrug-resistant Chronic Infections
      New work reveals that the chronic infections that impact CF patients may be vulnerable to some classes of antibiotics.
      Written By: Carmen Leitch
      1
      JAN 07, 2018
      Drug Discovery & Development
      Epigenomics for Diagnostics
      Epigenomics for Diagnostics
      The use of epigenetic profiling for diagnostics and predictive therapy is on the rise, here are 5 recommendations as th ...
      Written By: Courtney Schaal
      2
      JAN 06, 2018
      Genetics & Genomics
      Gene Fusion can Increase Likelihood of Cancer
      Gene Fusion can Increase Likelihood of Cancer
      Researchers have made a discovery about the fusion of adjacent genes that is leading to new cancer therapeutics.
      Written By: Carmen Leitch
      3
      JAN 04, 2018
      Health & Medicine
      A Micro-Needle Patch for Weight Loss?
      A Micro-Needle Patch for Weight Loss?
      The battle of the bulge is a daily struggle for some. No, not the World War II battle, but rather the fight so many wage ...
      Written By: Brenda Kelley Kim
      3 2
    MAR 01, 2018
    Drug Discovery & Development
    The 24 hour Flu-Killing Drug
    The 24 hour Flu-Killing Drug
    A pharmaceutical company, Shinogi, in Japan has developed an experimental drug that may kill the flu virus in as little ...
    Written By: Nouran Amin
    2
    FEB 28, 2018
    Immunology
    New Digital Imaging Analysis Spots HIV Degradation
    New Digital Imaging Analysis Spots HIV Degradation
    A new system that tracks proteins as they come and go in the cell is predicted to help scientists identify therapeutic t ...
    Written By: Kara Marker
    2
    FEB 27, 2018
    Cell & Molecular Biology
    Venom Compound Eases Arthritis Symptoms
    Venom Compound Eases Arthritis Symptoms
    Rheumatoid arthritis is an autoimmune disorder affecting around 1.3 million people. Those patients may eventually use a ...
    Written By: Carmen Leitch
    1 1
    FEB 26, 2018
    Microbiology
    Looking to Bacteria for the Next Antibiotic
    Looking to Bacteria for the Next Antibiotic
    Bacteria can be a surprising source of antibiotics. One example is Streptomyces chartreusis, which can secrete a variety ...
    Written By: Carmen Leitch
    1
    FEB 21, 2018
    Chemistry & Physics
    Smell of Death and the New Insights of Mood Disorders
    Smell of Death and the New Insights of Mood Disorders
    Eerie and distinctive, the smell of a dead body comes mainly from small molecules known as diamines, products of degrada ...
    Written By: Daniel Duan
    2
     
     
  • FEB 20, 2018
    Microbiology
    Insulin has Gone Viral
    Insulin has Gone Viral
    Our bodies need insulin to control the amount of sugar we have in our blood. Diabetes happens when that process fails, a ...
    Written By: Carmen Leitch
    1
    FEB 14, 2018
    Neuroscience
    Can Brain Damage From Alcohol Be Reversed?
    Can Brain Damage From Alcohol Be Reversed?
    Heavy consumption of alcohol over an extended period can negatively affect the brain. Neurogenesis, the ability of the b ...
    Written By: Brenda Kelley Kim
    2
    FEB 08, 2018
    Health & Medicine
    A Drug for Early Stage MS is Approved in Europe and the UK
    A Drug for Early Stage MS is Approved in Europe and the UK
    Multiple sclerosis (MS) is the most prevalent neurological disability around the globe. While onset could be at any age, ...
    Written By: Brenda Kelley Kim
    2
    FEB 07, 2018
    Immunology
    NOD2 Pathway Linked to Crohn's Disease and Multiple Sclerosis
    NOD2 Pathway Linked to Crohn's Disease and Multiple Sclerosis
    Defects in the body at the molecular level could at least partially explain why inflammatory diseases like Crohn’s ...
    Written By: Kara Marker
    2
    JAN 31, 2018
    Cell & Molecular Biology
    Getting to the Details of how Antipsychotic Drugs Work
    Getting to the Details of how Antipsychotic Drugs Work
    Around 1.6 percent of adults take antipsychotic medication, according to one study, but their mode of efficacy is not we ...
    Written By: Carmen Leitch
    2
     
     
  • JAN 27, 2018
    Genetics & Genomics
    A Botulinum Toxin Jumped to a new Species of Bacteria
    A Botulinum Toxin Jumped to a new Species of Bacteria
    Research shows how a bacterial pathogen that is resistant to antibiotics could potentially gain the ability to produce a ...
    Written By: Carmen Leitch
    2
    JAN 26, 2018
    Cardiology
    Heart Cells Sense Tension and Contraction in Heart Disease
    Heart Cells Sense Tension and Contraction in Heart Disease
    After a heart attack, heart cells lose sensitivity. According to recent discoveries from Queen Mary University of London ...
    Written By: Kara Marker
    3
    JAN 19, 2018
    Genetics & Genomics
    Amazing Images Reveal a Fundamental Process of Life
    Amazing Images Reveal a Fundamental Process of Life
    For the first time, scientists have captred images of the process by which DNA is transcribed into RNA
    Written By: Carmen Leitch
    2
    JAN 18, 2018
    Drug Discovery & Development
    Treatment of a Childhood Cancer: An Overview
    Treatment of a Childhood Cancer: An Overview
    Brief overview of Ewing sarcoma therapeutics
    Written By: Courtney Schaal
    2
    JAN 18, 2018
    Health & Medicine
    Cough Medicine, Opioids, and the FDA
    Cough Medicine, Opioids, and the FDA
    The opioid addiction epidemic is a serious health concern in the United States. Deaths from drug overdoses reached a hig ...
    Written By: Brenda Kelley Kim
    2
     
     
  • JAN 14, 2018
    Drug Discovery & Development
    Treatment for Aging Hearts: Exercise.
    Treatment for Aging Hearts: Exercise.
    It is well known exercise can prevent heart-related health issues, but recently researcher show it can actually reverse ...
    Written By: Courtney Schaal
    2
    JAN 12, 2018
    Cardiology
    Creating Stem Cells to See Heart Disease Like Never Before
    Creating Stem Cells to See Heart Disease Like Never Before
    A discovery arose from growing human arterial endothelial cells in the lab, and scientists from the Morgridge Institute ...
    Written By: Kara Marker
    3 1
    JAN 10, 2018
    Immunology
    New Treatment on the Horizon for Marburg Virus
    New Treatment on the Horizon for Marburg Virus
    For the first time, scientists have been able to gather evidence for a new antibody-based drug to treat people infected ...
    Written By: Kara Marker
    5
    JAN 09, 2018
    Drug Discovery & Development
    To fight the opioid epidemic, take drug makers to court?
    To fight the opioid epidemic, take drug makers to court?
    Litigation against drug manufacturers that produce and distribute opioids could be a promising option in the fight again ...
    Written By: The Scripps Research Institute (TSRI)
    3
    JAN 09, 2018
    Drug Discovery & Development
    Viruses could inspire nano drug-delivery device
    Viruses could inspire nano drug-delivery device
    Researchers have discovered a path toward virus-like, nanoscale devices that may be able to deliver drugs to cells by ch ...
    Written By: The Scripps Research Institute (TSRI)
    3
     
     
  • JAN 08, 2018
    Cell & Molecular Biology
    Treatment Strategies for Multidrug-resistant Chronic Infections
    Treatment Strategies for Multidrug-resistant Chronic Infections
    New work reveals that the chronic infections that impact CF patients may be vulnerable to some classes of antibiotics.
    Written By: Carmen Leitch
    1
    JAN 07, 2018
    Drug Discovery & Development
    Epigenomics for Diagnostics
    Epigenomics for Diagnostics
    The use of epigenetic profiling for diagnostics and predictive therapy is on the rise, here are 5 recommendations as th ...
    Written By: Courtney Schaal
    2
    JAN 06, 2018
    Genetics & Genomics
    Gene Fusion can Increase Likelihood of Cancer
    Gene Fusion can Increase Likelihood of Cancer
    Researchers have made a discovery about the fusion of adjacent genes that is leading to new cancer therapeutics.
    Written By: Carmen Leitch
    3
    JAN 04, 2018
    Health & Medicine
    A Micro-Needle Patch for Weight Loss?
    A Micro-Needle Patch for Weight Loss?
    The battle of the bulge is a daily struggle for some. No, not the World War II battle, but rather the fight so many wage ...
    Written By: Brenda Kelley Kim
    3 2
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