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Drug Discovery
Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
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NOV 06, 2016Cell & Molecular Biology
Neglected diseases are those that affect the world’s poor and are usually common in tropical areas. A new discover ...Written By: Carmen LeitchNOV 01, 2016Cell & Molecular Biology
LA JOLLA, CA – November 1, 2016 – Scientists at The Scripps Research Institute (TSRI) have developed a broad ...Written By: The Scripps Research Institute (TSRI)OCT 25, 2016Neuroscience
Feeling down? It’s all in your head but now researchers know where. Depression is often associated with a stigma t ...Written By: Brenda Kelley KimOCT 24, 2016Cell & Molecular Biology
For people that suffer from diseases with no treatments, the outlook can be bleak. One such illness is Charcot-Marie-Too ...Written By: Carmen LeitchOCT 21, 2016Health & Medicine
JUPITER, FL — October 20, 2016 – In a discovery that advances the understanding of how marijuana works in th ...Written By: The Scripps Research Institute (TSRI)OCT 19, 2016Videos
In 1928, Alexander Fleming transformed the world of medicine with the discovery of the first antibiotic, penicillin. Sci ...OCT 05, 2016Cancer
A drug that’s approved for the treatment of kidney cancer could find renewed purpose against other cancer types to ...OCT 04, 2016Cell & Molecular Biology
The 2016 Nobel Prize in Physiology or Medicine has been awarded to Yoshinori Ohsumi for his influential work inves ...Written By: Carmen LeitchSEP 26, 2016Immunology
A new drug candidate for multiple sclerosis (MS) was successfully tested in mice models of the disease. The drug, called ...Written By: Kara MarkerSEP 23, 2016Cancer
Earlier this week, I reported that scientists discovered how some cancers apparently switched off their sweet tooth to b ...SEP 20, 2016Immunology
Norovirus is the most common viral cause of diarrhea worldwide, but because of an inability to grow it in a lab, scienti ...Written By: Futurity (futurity.org)SEP 16, 2016Health & Medicine
LA JOLLA, CA—September 16, 2016—Scientists at The Scripps Research Institute (TSRI) have discovered a potent ...Written By: The Scripps Research Institute (TSRI)SEP 10, 2016Cell & Molecular Biology
Heat shock proteins are known to help the body respond to stress, but new research appears to implicate one of them, Hsp ...Written By: Carmen LeitchAUG 31, 2016Immunology
Replacing faulty stem cells in the bone marrow with a transplant is one way to treat some bone cancers, but the immune r ...Written By: Kara MarkerAUG 26, 2016Immunology
When four children from Pakistani and Turkish families presented with skin rashes and inflamed joints that doctors could ...Written By: Kara MarkerAUG 22, 2016Cancer
Just because a chemotherapeutic drug exist does not mean it will work for every patient. There has been no other time wh ...AUG 19, 2016Immunology
Sometimes the immune system can react too strongly to influenza infections and cause lethal complications of pneumonia. ...Written By: Kara MarkerAUG 14, 2016Immunology
Image Credit: Guilhem Vellut/Flickr The microenvironment that supports a cancerous tumor also starves the immune cells t ...Written By: Futurity (futurity.org)AUG 13, 2016Neuroscience
Perhaps one of the best outcomes for pharmacologists is the discovery that common, pre-existing drugs could treat new co ...AUG 08, 2016Cell & Molecular Biology
In the study of cell signaling, one well established paradigm is that receptors on the surface of cells receive input fr ...Written By: Carmen LeitchJUL 31, 2016Videos
The Africa Health Research Institute has been established to fight both HIV and tuberculosis (TB) in South Africa and be ...Written By: Carmen LeitchJUL 27, 2016Immunology
Image Credit: iStockphoto A new discovery could one day improve treatments for lupus sufferers, saving thousands of ...Written By: Futurity (futurity.org)JUL 22, 2016Cancer
Nausea and vomiting are among the most common adverse side effects of chemotherapy. In fact, some drugs induce such seve ...JUL 21, 2016Neuroscience
In the field of neuroscience, and specifically research, the greatest need is arguably in the area of brain tumors. One ...Written By: Brenda Kelley Kim
NOV 06, 2016
Cell & Molecular Biology
Neglected diseases are those that affect the world’s poor and are usually common in tropical areas. A new discover
...
Written By:
Carmen Leitch
NOV 01, 2016
Cell & Molecular Biology
LA JOLLA, CA – November 1, 2016 – Scientists at The Scripps Research Institute (TSRI) have developed a broad
...
Written By:
The Scripps Research Institute (TSRI)
OCT 25, 2016
Neuroscience
Feeling down? It’s all in your head but now researchers know where. Depression is often associated with a stigma t
...
Written By:
Brenda Kelley Kim
OCT 24, 2016
Cell & Molecular Biology
For people that suffer from diseases with no treatments, the outlook can be bleak. One such illness is Charcot-Marie-Too
...
Written By:
Carmen Leitch
OCT 21, 2016
Health & Medicine
JUPITER, FL — October 20, 2016 – In a discovery that advances the understanding of how marijuana works in th
...
Written By:
The Scripps Research Institute (TSRI)
OCT 19, 2016
Videos
In 1928, Alexander Fleming transformed the world of medicine with the discovery of the first antibiotic, penicillin. Sci
...
OCT 05, 2016
Cancer
A drug that’s approved for the treatment of kidney cancer could find renewed purpose against other cancer types to
...
OCT 04, 2016
Cell & Molecular Biology
The 2016 Nobel Prize in Physiology or Medicine has been awarded to Yoshinori Ohsumi for his influential work inves
...
Written By:
Carmen Leitch
SEP 26, 2016
Immunology
A new drug candidate for multiple sclerosis (MS) was successfully tested in mice models of the disease. The drug, called
...
Written By:
Kara Marker
SEP 23, 2016
Cancer
Earlier this week, I reported that scientists discovered how some cancers apparently switched off their sweet tooth to b
...
SEP 20, 2016
Immunology
Norovirus is the most common viral cause of diarrhea worldwide, but because of an inability to grow it in a lab, scienti
...
Written By:
Futurity (futurity.org)
SEP 16, 2016
Health & Medicine
LA JOLLA, CA—September 16, 2016—Scientists at The Scripps Research Institute (TSRI) have discovered a potent
...
Written By:
The Scripps Research Institute (TSRI)
SEP 10, 2016
Cell & Molecular Biology
Heat shock proteins are known to help the body respond to stress, but new research appears to implicate one of them, Hsp
...
Written By:
Carmen Leitch
AUG 31, 2016
Immunology
Replacing faulty stem cells in the bone marrow with a transplant is one way to treat some bone cancers, but the immune r
...
Written By:
Kara Marker
AUG 26, 2016
Immunology
When four children from Pakistani and Turkish families presented with skin rashes and inflamed joints that doctors could
...
Written By:
Kara Marker
AUG 22, 2016
Cancer
Just because a chemotherapeutic drug exist does not mean it will work for every patient. There has been no other time wh
...
AUG 19, 2016
Immunology
Sometimes the immune system can react too strongly to influenza infections and cause lethal complications of pneumonia.
...
Written By:
Kara Marker
AUG 14, 2016
Immunology
Image Credit: Guilhem Vellut/Flickr The microenvironment that supports a cancerous tumor also starves the immune cells t
...
Written By:
Futurity (futurity.org)
AUG 13, 2016
Neuroscience
Perhaps one of the best outcomes for pharmacologists is the discovery that common, pre-existing drugs could treat new co
...
AUG 08, 2016
Cell & Molecular Biology
In the study of cell signaling, one well established paradigm is that receptors on the surface of cells receive input fr
...
Written By:
Carmen Leitch
JUL 31, 2016
Videos
The Africa Health Research Institute has been established to fight both HIV and tuberculosis (TB) in South Africa and be
...
Written By:
Carmen Leitch
JUL 27, 2016
Immunology
Image Credit: iStockphoto A new discovery could one day improve treatments for lupus sufferers, saving thousands of
...
Written By:
Futurity (futurity.org)
JUL 22, 2016
Cancer
Nausea and vomiting are among the most common adverse side effects of chemotherapy. In fact, some drugs induce such seve
...
JUL 21, 2016
Neuroscience
In the field of neuroscience, and specifically research, the greatest need is arguably in the area of brain tumors. One
...
Written By:
Brenda Kelley Kim